Published in Oncogene on January 12, 2009
MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer (2009) 2.45
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev (2010) 2.37
MicroRNAs and their isomiRs function cooperatively to target common biological pathways. Genome Biol (2011) 2.15
MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer. BMC Cancer (2010) 2.10
Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis. Cancer Res (2010) 1.88
miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice. PLoS One (2009) 1.84
A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. EMBO J (2012) 1.82
MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression. Mol Ther (2011) 1.77
Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer. Mol Syst Biol (2012) 1.69
MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. Oncogene (2012) 1.63
Implication of microRNAs in drug resistance for designing novel cancer therapy. Drug Resist Updat (2010) 1.61
Epigenetics of colorectal cancer. Gastroenterology (2012) 1.60
Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT. PLoS One (2011) 1.55
MicroRNA-145 regulates chondrogenic differentiation of mesenchymal stem cells by targeting Sox9. PLoS One (2011) 1.47
miR-135b Promotes Cancer Progression by Targeting Transforming Growth Factor Beta Receptor II (TGFBR2) in Colorectal Cancer. PLoS One (2015) 1.46
MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma. Oncotarget (2014) 1.44
An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell (2014) 1.44
The role of microRNAs in colorectal cancer. Cancer J (2012) 1.44
MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1). J Biol Chem (2013) 1.43
MicroRNA signature analysis in colorectal cancer: identification of expression profiles in stage II tumors associated with aggressive disease. Int J Colorectal Dis (2011) 1.43
Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma. Cancer Res (2011) 1.40
Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research. Pharm Res (2010) 1.40
Identification and evaluation of plasma microRNAs for early detection of colorectal cancer. PLoS One (2013) 1.39
MicroRNA Involvement in Osteosarcoma. Sarcoma (2012) 1.38
Novel classes of non-coding RNAs and cancer. J Transl Med (2012) 1.35
Identifying microRNA-mRNA regulatory network in colorectal cancer by a combination of expression profile and bioinformatics analysis. BMC Syst Biol (2012) 1.35
Lessons from miR-143/145: the importance of cell-type localization of miRNAs. Nucleic Acids Res (2014) 1.34
Downregulation of six microRNAs is associated with advanced stage, lymph node metastasis and poor prognosis in small cell carcinoma of the cervix. PLoS One (2012) 1.31
MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer. Mol Cancer (2012) 1.30
MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors. PLoS One (2012) 1.27
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. PLoS One (2013) 1.22
miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation. PLoS One (2011) 1.21
miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes. Inflamm Bowel Dis (2011) 1.20
Novel allosteric sites on Ras for lead generation. PLoS One (2011) 1.20
The impact of microRNAs on colorectal cancer. Virchows Arch (2009) 1.20
The regulation of Toll-like receptor 2 by miR-143 suppresses the invasion and migration of a subset of human colorectal carcinoma cells. Mol Cancer (2013) 1.19
Alterations of microRNAs contribute to colon carcinogenesis. Semin Oncol (2011) 1.19
EGFR signals downregulate tumor suppressors miR-143 and miR-145 in Western diet-promoted murine colon cancer: role of G1 regulators. Mol Cancer Res (2011) 1.18
miR-143 and miR-145 synergistically regulate ERBB3 to suppress cell proliferation and invasion in breast cancer. Mol Cancer (2014) 1.17
miRNA expressions in rectal cancer as predictors of response to neoadjuvant chemoradiation therapy. Int J Colorectal Dis (2012) 1.16
MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells. BMC Cancer (2012) 1.16
Differential expression of microRNAs in tumors from chronically inflamed or genetic (APC(Min/+)) models of colon cancer. PLoS One (2011) 1.16
Serum microRNA panel as biomarkers for early diagnosis of colorectal adenocarcinoma. Br J Cancer (2014) 1.13
MicroRNA-143 inhibits migration and invasion of human non-small-cell lung cancer and its relative mechanism. Int J Biol Sci (2013) 1.13
Recent insights into the pathogenesis of colorectal cancer. Curr Opin Gastroenterol (2010) 1.13
Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met. Oncotarget (2015) 1.13
Microprocessor of microRNAs: regulation and potential for therapeutic intervention. Mol Cancer (2010) 1.11
Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene. PLoS One (2012) 1.10
The role of microRNAs in ovarian cancer initiation and progression. J Cell Mol Med (2010) 1.08
Changes in microRNA expression in the MG-63 osteosarcoma cell line compared with osteoblasts. Oncol Lett (2012) 1.08
MicroRNA-143 suppresses gastric cancer cell growth and induces apoptosis by targeting COX-2. World J Gastroenterol (2013) 1.07
Prognostic and predictive roles of KRAS mutation in colorectal cancer. Int J Mol Sci (2012) 1.07
Identification of novel and differentially expressed MicroRNAs of dairy goat mammary gland tissues using solexa sequencing and bioinformatics. PLoS One (2012) 1.06
Reprogramming of the microRNA transcriptome mediates resistance to rapamycin. J Biol Chem (2013) 1.06
The Diagnostic and Prognostic Role of microRNA in Colorectal Cancer - a Comprehensive review. J Cancer (2013) 1.05
Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer. Br J Cancer (2012) 1.04
Effects of the miR-143/-145 microRNA cluster on the colon cancer proteome and transcriptome. J Proteome Res (2012) 1.03
Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells. BMC Cancer (2012) 1.02
Expression profile of microRNAs in Epstein-Barr virus-infected AGS gastric carcinoma cells. J Virol (2013) 1.02
Role of microRNAs in the immune system, inflammation and cancer. World J Gastroenterol (2013) 1.02
Exosome can prevent RNase from degrading microRNA in feces. J Gastrointest Oncol (2011) 1.01
MicroRNAs in colorectal carcinoma - from pathogenesis to therapy. J Exp Clin Cancer Res (2016) 1.00
Discovery of MicroRNAs associated with myogenesis by deep sequencing of serial developmental skeletal muscles in pigs. PLoS One (2012) 1.00
Regulation of senescence by microRNA biogenesis factors. Ageing Res Rev (2012) 0.99
MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. PLoS One (2014) 0.99
Cardio-miRNAs and onco-miRNAs: circulating miRNA-based diagnostics for non-cancerous and cancerous diseases. Front Cell Dev Biol (2014) 0.99
MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma. Oncotarget (2014) 0.98
miR-203 suppresses the proliferation and migration and promotes the apoptosis of lung cancer cells by targeting SRC. PLoS One (2014) 0.98
Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development. Cancer Discov (2015) 0.97
MicroRNAs in pancreatic cancer metabolism. Nat Rev Gastroenterol Hepatol (2012) 0.97
Overexpressed let-7a inhibits glioma cell malignancy by directly targeting K-ras, independently of PTEN. Neuro Oncol (2013) 0.96
Identification of non-coding RNAs embracing microRNA-143/145 cluster. Mol Cancer (2010) 0.96
Mechanistic aspects of COX-2 expression in colorectal neoplasia. Recent Results Cancer Res (2013) 0.95
MicroRNAs, development of Barrett's esophagus, and progression to esophageal adenocarcinoma. World J Gastroenterol (2010) 0.95
miRNAs versus oncogenes: the power of social networking. Mol Syst Biol (2012) 0.95
MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer. Oncotarget (2016) 0.94
miR-193a-3p functions as a tumor suppressor in lung cancer by down-regulating ERBB4. J Biol Chem (2014) 0.93
miR-143 decreases COX-2 mRNA stability and expression in pancreatic cancer cells. Biochem Biophys Res Commun (2013) 0.93
The proto-oncogene KRAS is targeted by miR-200c. Oncotarget (2014) 0.93
Gene dysregulations driven by somatic copy number aberrations-biological and clinical implications in colon tumors: a paper from the 2009 William Beaumont Hospital Symposium on Molecular Pathology. J Mol Diagn (2010) 0.93
miR-20a and miR-290, multi-faceted players with a role in tumourigenesis and senescence. J Cell Mol Med (2010) 0.93
MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer. World J Gastroenterol (2014) 0.93
Beyond KRAS mutation status: influence of KRAS copy number status and microRNAs on clinical outcome to cetuximab in metastatic colorectal cancer patients. BMC Cancer (2012) 0.92
MicroRNAs as Novel Biomarkers in Colorectal Cancer. Front Genet (2012) 0.92
Tumor suppressors miR-143 and miR-145 and predicted target proteins API5, ERK5, K-RAS, and IRS-1 are differentially expressed in proximal and distal colon. Am J Physiol Gastrointest Liver Physiol (2014) 0.92
MicroRNAs targeting EGFR signalling pathway in colorectal cancer. J Cancer Res Clin Oncol (2013) 0.91
MicroRNA-143 regulates collagen type III expression in stromal fibroblasts of scirrhous type gastric cancer. Cancer Sci (2014) 0.91
MicroRNAs: promising biomarkers for diagnosis and therapeutic targets in human colorectal cancer metastasis. BMB Rep (2015) 0.91
MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms. Br J Cancer (2015) 0.90
miR-134 functions as a tumor suppressor in cell proliferation and epithelial-to-mesenchymal Transition by targeting KRAS in renal cell carcinoma cells. DNA Cell Biol (2015) 0.90
Glycolysis in Panc-1 human pancreatic cancer cells is inhibited by everolimus. Exp Ther Med (2012) 0.90
microRNAs in cancer cell response to ionizing radiation. Antioxid Redox Signal (2014) 0.90
miRNAs as biomarkers in colorectal cancer diagnosis and prognosis. Bioanalysis (2010) 0.89
MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1. Protein Cell (2014) 0.89
Regulation of Aerobic Glycolysis by microRNAs in Cancer. Mol Cell Pharmacol (2011) 0.89
MicroRNAs: Clinical Relevance in Colorectal Cancer. Int J Mol Sci (2015) 0.89
Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. Oncotarget (2015) 0.89
MicroRNAs in colorectal cancer: role in metastasis and clinical perspectives. World J Gastroenterol (2014) 0.89
MicroRNA manipulation in colorectal cancer cells: from laboratory to clinical application. J Transl Med (2012) 0.88
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