Published in Science on November 12, 1999
Physiological functions of the HECT family of ubiquitin ligases. Nat Rev Mol Cell Biol (2009) 5.43
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature (2005) 4.63
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature (2011) 3.40
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5. Nat Struct Mol Biol (2006) 2.85
Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase. Mol Cell Biol (2000) 2.79
Angelman syndrome: a review of the clinical and genetic aspects. J Med Genet (2003) 2.69
Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases. Proc Natl Acad Sci U S A (2005) 2.60
Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex. Mol Cell (2009) 2.58
Identification, analysis, and prediction of protein ubiquitination sites. Proteins (2010) 2.53
Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages. Nat Rev Mol Cell Biol (2012) 2.53
Structure and functional interactions of the Tsg101 UEV domain. EMBO J (2002) 2.40
A conserved catalytic residue in the ubiquitin-conjugating enzyme family. EMBO J (2003) 2.37
HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway. J Cell Biol (2004) 2.34
The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity. EMBO J (2006) 2.21
The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev (2001) 2.18
Polyubiquitination by HECT E3s and the determinants of chain type specificity. Mol Cell Biol (2009) 2.17
Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. Mol Cell (2012) 2.07
Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor. Am J Hum Genet (2007) 2.07
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell (2009) 2.04
Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex. EMBO J (2002) 1.98
HECT and RING finger families of E3 ubiquitin ligases at a glance. J Cell Sci (2012) 1.95
Getting into position: the catalytic mechanisms of protein ubiquitylation. Biochem J (2004) 1.83
New insights into ubiquitin E3 ligase mechanism. Nat Struct Mol Biol (2014) 1.82
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions. Cell Death Differ (2010) 1.77
Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways. Curr Opin Struct Biol (2007) 1.76
The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics (2012) 1.73
Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol Biol Cell (2003) 1.72
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. Nat Struct Mol Biol (2004) 1.72
E2s: structurally economical and functionally replete. Biochem J (2011) 1.64
Control of biochemical reactions through supramolecular RING domain self-assembly. Proc Natl Acad Sci U S A (2002) 1.63
Molecular basis for the association of human E4B U box ubiquitin ligase with E2-conjugating enzymes UbcH5c and Ubc4. Structure (2010) 1.58
Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis. EMBO J (2005) 1.56
Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation. EMBO Rep (2011) 1.55
UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis. Cell Rep (2015) 1.52
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat Commun (2013) 1.51
System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol Cell (2016) 1.49
Structure-based protocol for identifying mutations that enhance protein-protein binding affinities. J Mol Biol (2007) 1.48
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism. Structure (2013) 1.48
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. Mol Syst Biol (2009) 1.43
Regulation of catalytic activities of HECT ubiquitin ligases. Biochem Biophys Res Commun (2007) 1.42
Regulation of the RSP5 ubiquitin ligase by an intrinsic ubiquitin-binding site. J Biol Chem (2009) 1.42
Structure and function of a HECT domain ubiquitin-binding site. EMBO Rep (2011) 1.35
Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase. J Virol (2000) 1.34
Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway. Mol Cell Biol (2001) 1.34
Comparative analysis of protein structure alignments. BMC Struct Biol (2007) 1.28
Molecular and Clinical Aspects of Angelman Syndrome. Mol Syndromol (2011) 1.27
Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3. Elife (2013) 1.27
The papillomavirus E7 oncoprotein is ubiquitinated by UbcH7 and Cullin 1- and Skp2-containing E3 ligase. J Virol (2004) 1.25
Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases. Curr Opin Microbiol (2009) 1.23
The role of the selective adaptor p62 and ubiquitin-like proteins in autophagy. Biomed Res Int (2014) 1.21
A Drosophila model for Angelman syndrome. Proc Natl Acad Sci U S A (2008) 1.21
Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase. Proc Natl Acad Sci U S A (2010) 1.20
Molecular mechanisms of ubiquitin-dependent membrane traffic. Annu Rev Biophys (2011) 1.19
Sequence determinants of E2-E6AP binding affinity and specificity. J Mol Biol (2007) 1.19
Bi-directional SIFT predicts a subset of activating mutations. PLoS One (2009) 1.19
HECT E3s and human disease. BMC Biochem (2007) 1.19
The basis for selective E1-E2 interactions in the ISG15 conjugation system. J Biol Chem (2008) 1.17
Polyreactivity and autoreactivity among HIV-1 antibodies. J Virol (2014) 1.15
The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance. Semin Immunol (2007) 1.13
RBR E3 ubiquitin ligases: new structures, new insights, new questions. Biochem J (2014) 1.13
Perilous journey: a tour of the ubiquitin-proteasome system. Trends Cell Biol (2014) 1.11
E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1). Proc Natl Acad Sci U S A (2005) 1.11
Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p. EMBO Rep (2003) 1.09
HPV E6, E6AP and cervical cancer. BMC Biochem (2008) 1.08
Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection. Structure (2014) 1.08
G2E3 is a dual function ubiquitin ligase required for early embryonic development. J Biol Chem (2008) 1.08
Pressure-induced differential regulation of the two tryptophan permeases Tat1 and Tat2 by ubiquitin ligase Rsp5 and its binding proteins, Bul1 and Bul2. Mol Cell Biol (2003) 1.08
The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors. Mol Cell Biol (2004) 1.08
Method for targeting protein destruction by using a ubiquitin-independent, proteasome-mediated degradation pathway. Proc Natl Acad Sci U S A (2005) 1.07
Structural and functional insights to ubiquitin-like protein conjugation. Annu Rev Biophys (2014) 1.07
Ubiquitin in the immune system. EMBO Rep (2013) 1.06
Human proteome-scale structural modeling of E2-E3 interactions exploiting interface motifs. J Proteome Res (2012) 1.05
Computational design of second-site suppressor mutations at protein-protein interfaces. Proteins (2010) 1.04
E6-associated protein (E6-AP) is a dual function coactivator of steroid hormone receptors. Nucl Recept Signal (2008) 1.04
Engineering a protein-protein interface using a computationally designed library. Proc Natl Acad Sci U S A (2010) 1.03
Tumor viruses and cell signaling pathways: deubiquitination versus ubiquitination. Mol Cell Biol (2004) 1.02
Peptide and small molecule inhibitors of HECT-type ubiquitin ligases. Proc Natl Acad Sci U S A (2014) 1.02
Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. Biochemistry (2012) 1.02
The Arabidopsis KAKTUS gene encodes a HECT protein and controls the number of endoreduplication cycles. Mol Genet Genomics (2003) 1.01
A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase. Proc Natl Acad Sci U S A (2007) 1.01
HACE1: A novel repressor of RAR transcriptional activity. J Cell Biochem (2009) 1.00
A pathogen type III effector with a novel E3 ubiquitin ligase architecture. PLoS Pathog (2013) 0.99
SUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavage. J Biol Chem (2008) 0.99
Novel control of S phase of the cell cycle by ubiquitin-conjugating enzyme H7. Mol Biol Cell (2008) 0.98
Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2. J Biol Chem (2011) 0.98
Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions. Proc Natl Acad Sci U S A (2012) 0.98
Participation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel. Mol Cell Biol (2004) 0.97
SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1. EMBO J (2011) 0.97
E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP. J Biol Chem (2011) 0.97
E1-E2 interactions in ubiquitin and Nedd8 ligation pathways. J Biol Chem (2011) 0.96
Biochemical and structural studies of a HECT-like ubiquitin ligase from Escherichia coli O157:H7. J Biol Chem (2010) 0.96
The proinflammatory role of HECTD2 in innate immunity and experimental lung injury. Sci Transl Med (2015) 0.96
The HECT domain of the ubiquitin ligase Rsp5 contributes to substrate recognition. J Biol Chem (2009) 0.95
Macromolecular juggling by ubiquitylation enzymes. BMC Biol (2013) 0.95
Human papillomavirus 16 E6 is associated with the nuclear matrix of esophageal carcinoma cells. World J Gastroenterol (2001) 0.94
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7). Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.94
The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates. J Biol Chem (2013) 0.93
The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling. Proc Natl Acad Sci U S A (2014) 0.93
E6AP/UBE3A ubiquitin ligase harbors two E2~ubiquitin binding sites. J Biol Chem (2013) 0.92
A structural element within the HUWE1 HECT domain modulates self-ubiquitination and substrate ubiquitination activities. J Biol Chem (2009) 0.92
The sequence of the human genome. Science (2001) 101.55
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell (1990) 20.60
Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science (1996) 19.48
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (1989) 16.54
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science (1994) 13.51
Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (1990) 12.88
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell (1993) 12.41
Highly pathogenic H5N1 influenza virus infection in migratory birds. Science (2005) 9.64
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science (1996) 9.48
Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc Natl Acad Sci U S A (1981) 9.27
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature (1995) 9.03
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J Virol (1989) 8.68
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell (2000) 7.82
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J (1989) 7.69
Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product. Cell (1985) 7.56
Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature (1999) 7.47
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell (1998) 7.01
Bovine papillomavirus contains multiple transforming genes. Proc Natl Acad Sci U S A (1985) 6.73
In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA. Nature (1980) 6.67
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature (1996) 6.67
Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J Virol (1987) 6.65
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell (1999) 6.59
The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell (1988) 6.28
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am J Pathol (1985) 6.18
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature (1995) 5.89
A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell (1987) 5.75
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell (1997) 5.73
Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function. Science (1999) 5.72
A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J (1991) 5.39
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci U S A (1995) 5.37
A rapid method for detecting and mapping homology between heterologous DNAs. Evaluation of polyomavirus genomes. J Biol Chem (1979) 5.32
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc Natl Acad Sci U S A (1991) 5.31
A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding. Proc Natl Acad Sci U S A (2000) 5.30
Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria. Proc Natl Acad Sci U S A (1982) 5.22
Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses. Proc Natl Acad Sci U S A (1986) 4.89
Localization and analysis of bovine papillomavirus type 1 transforming functions. J Virol (1984) 4.77
Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Mol Cell Biol (1981) 4.75
Virus-specific transcription in bovine papillomavirus-transformed mouse cells. Virology (1982) 4.52
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature (2000) 4.52
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Proc Natl Acad Sci U S A (1997) 4.38
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes Dev (1998) 4.06
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol Cell Biol (1993) 4.04
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. Cell (1998) 3.86
Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat Struct Biol (1996) 3.81
Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissues. EMBO J (1987) 3.77
Structures of the native and swollen forms of cowpea chlorotic mottle virus determined by X-ray crystallography and cryo-electron microscopy. Structure (1995) 3.76
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science (1995) 3.69
Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region. J Virol (1987) 3.66
Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene (2009) 3.64
Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1. Nature (1986) 3.63
Multiplex PCR for detection of genes for Staphylococcus aureus enterotoxins, exfoliative toxins, toxic shock syndrome toxin 1, and methicillin resistance. J Clin Microbiol (2000) 3.59
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell (1990) 3.55
In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res (1996) 3.50
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell (2000) 3.39
In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J Cell Biol (1998) 3.38
Cloning of human papilloma virus genomic DNAs and analysis of homologous polynucleotide sequences. J Virol (1980) 3.34
Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun (1996) 3.33
A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature (1997) 3.29
p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell (1998) 3.27
The papillomavirus E2 regulatory proteins. J Biol Chem (1991) 3.27
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product. J Virol (1987) 3.24
The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity. EMBO J (1988) 3.20
E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc Natl Acad Sci U S A (1989) 3.18
Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells. J Biol Chem (1999) 3.17
Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol Cell (1998) 3.12
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc Natl Acad Sci U S A (1994) 3.12
Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7. Nature (1998) 3.01
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J (1992) 2.97
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol Cell Biol (1993) 2.91
Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J Virol (1990) 2.90
A novel type of human papillomavirus associated with genital neoplasias. Nature (1986) 2.89
Factors affecting reliability and reproducibility of amplification-based DNA fingerprinting of representative bacterial pathogens. J Clin Microbiol (1997) 2.87
Transcriptional organization of bovine papillomavirus type 1. J Virol (1983) 2.84
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol (2001) 2.81
Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase. Mol Cell Biol (2000) 2.79
Identification of verotoxin type 2 variant B subunit genes in Escherichia coli by the polymerase chain reaction and restriction fragment length polymorphism analysis. J Clin Microbiol (1991) 2.78
Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice. J Virol (1994) 2.73
Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev (1999) 2.73
Comparative analysis of the human type 1a and bovine type 1 papillomavirus genomes. J Virol (1983) 2.69
Rhabdoviruses and the cellular ubiquitin-proteasome system: a budding interaction. J Virol (2001) 2.66
Bovine papillomavirus type 1 3' early region transformation and plasmid maintenance functions. J Virol (1986) 2.62
The health effects of swimming in ocean water contaminated by storm drain runoff. Epidemiology (1999) 2.58
Role of the F-box protein Skp2 in lymphomagenesis. Proc Natl Acad Sci U S A (2001) 2.55
Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer. Oncogene (2000) 2.55
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature (1998) 2.52
A clinical and immunologic evaluation of women with silicone breast implants and symptoms of rheumatic disease. Ann Intern Med (1993) 2.50
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B. J Biol Chem (2001) 2.50
Case study of the effects of atmospheric aerosols and regional haze on agriculture: an opportunity to enhance crop yields in China through emission controls? Proc Natl Acad Sci U S A (1999) 2.44
Transient replication of human papillomavirus DNAs. J Virol (1992) 2.43
Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain. J Neurosci (2001) 2.41