Published in FASEB J on January 13, 2009
Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature (2010) 6.20
Forcing cells to change lineages. Nature (2009) 5.99
Nuclear reprogramming to a pluripotent state by three approaches. Nature (2010) 5.26
DNA methylation and cellular reprogramming. Trends Cell Biol (2010) 1.77
Molecular roadblocks for cellular reprogramming. Mol Cell (2012) 1.74
Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming. Cancer Res (2011) 1.73
Maintaining differentiated cellular identity. Nat Rev Genet (2012) 1.32
The problem of colliding networks and its relation to cell fusion and cancer. Biophys J (2012) 1.00
Zfp296 is a novel, pluripotent-specific reprogramming factor. PLoS One (2012) 1.00
Efficiencies and mechanisms of nuclear reprogramming. Cold Spring Harb Symp Quant Biol (2010) 0.92
Electrofusion of mesenchymal stem cells and islet cells for diabetes therapy: a rat model. PLoS One (2013) 0.87
Using heterokaryons to understand pluripotency and reprogramming. Philos Trans R Soc Lond B Biol Sci (2011) 0.87
Cell fusion reprogramming leads to a specific hepatic expression pattern during mouse bone marrow derived hepatocyte formation in vivo. PLoS One (2012) 0.85
Targeted cell fusion facilitates stable heterokaryon generation in vitro and in vivo. PLoS One (2011) 0.80
Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells. Cell Cycle (2015) 0.80
Intra-hematopoietic cell fusion as a source of somatic variation in the hematopoietic system. J Cell Sci (2012) 0.79
In-vivo fusion of human cancer and hamster stromal cells permanently transduces and transcribes human DNA. PLoS One (2014) 0.79
Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells. Genome Res (2013) 0.79
Single-cell RNA-seq reveals activation of unique gene groups as a consequence of stem cell-parenchymal cell fusion. Sci Rep (2016) 0.78
AID hits the jackpot when missing the target. Curr Opin Immunol (2016) 0.78
Phenotypic changes in growth-arrested T cell hybrids: a possible avenue to produce functional T cell hybridoma. Front Immunol (2014) 0.77
The shock of being united and symphiliosis. Another lesson from plants? Cell Cycle (2014) 0.77
Incomplete reprogramming after fusion of human multipotent stromal cells and bronchial epithelial cells. FASEB J (2010) 0.77
Viral-mediated fusion of mesenchymal stem cells with cells of the infarcted heart hinders healing via decreased vascularization and immune modulation. Sci Rep (2016) 0.75
Mesenchymal stem cells generate distinct functional hybrids in vitro via cell fusion or entosis. Sci Rep (2016) 0.75
β-MSCs: successful fusion of MSCs with β-cells results in a β-cell like phenotype. Oncotarget (2016) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77
Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc Natl Acad Sci U S A (1989) 7.19
Plasticity of the differentiated state. Science (1985) 6.19
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science (2005) 6.14
Reverse transcriptase template switching: a SMART approach for full-length cDNA library construction. Biotechniques (2001) 5.92
Cytoplasmic activation of human nuclear genes in stable heterocaryons. Cell (1983) 5.71
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol (2001) 5.42
Nanog promotes transfer of pluripotency after cell fusion. Nature (2006) 4.38
Rapid reprogramming of globin gene expression in transient heterokaryons. Cell (1986) 2.90
Differentiation requires continuous regulation. J Cell Biol (1991) 2.56
Expression of differentiated functions in hepatoma cell hybrids: induction of mouse albumin production in rat hepatoma-mouse fibroblast hybrids. Proc Natl Acad Sci U S A (1972) 1.90
Detection of mutations by cleavage of DNA heteroduplexes with bacteriophage resolvases. Nat Genet (1995) 1.79
Microarray-based analysis of gene expression in very large gene families: the cytochrome P450 gene superfamily of Arabidopsis thaliana. Gene (2001) 1.67
A method for cross-species gene expression analysis with high-density oligonucleotide arrays. Nucleic Acids Res (2004) 1.51
Differentiation requires continuous active control. Annu Rev Biochem (1992) 1.41
Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons. Proc Natl Acad Sci U S A (2007) 1.40
In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip technology. BMC Genomics (2005) 1.39
Induction of muscle genes in neural cells. J Cell Biol (1984) 1.36
Human serum albumin phenotype activation in mouse hepatoma--human leukocyte cell hybrids. Science (1974) 1.33
Role of alpha-fetoprotein regulatory elements in transcriptional activation in transient heterokaryons. Mol Cell Biol (1990) 1.30
Cell-type-specific transcriptomics in chimeric models using transcriptome-based masks. Nucleic Acids Res (2005) 1.27
Expression of differentiated functions in heterokaryons between skeletal myocytes, adrenal cells, fibroblasts and glial cells. Exp Cell Res (1984) 1.24
Expression of muscle genes in heterokaryons depends on gene dosage. J Cell Biol (1986) 1.21
Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming. J Cell Sci (2006) 1.19
Genome-wide reprogramming in hybrids of somatic cells and embryonic stem cells. Stem Cells (2007) 1.16
Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays. BMC Genomics (2004) 1.16
Phenotypic exclusion in mouse melanoma-rat hepatoma hybrid cells: pigment and albumin production are not reexpressed simultaneously. Cell (1978) 1.13
Malignancy of somatic cell hybrids. Nature (1969) 0.98
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature (2010) 14.62
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat Cell Biol (2005) 7.69
Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature (2010) 6.20
Self-renewal and expansion of single transplanted muscle stem cells. Nature (2008) 5.57
Nuclear reprogramming to a pluripotent state by three approaches. Nature (2010) 5.26
A public genome-scale lentiviral expression library of human ORFs. Nat Methods (2011) 4.98
Designing materials to direct stem-cell fate. Nature (2009) 4.86
Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury. Cell (2002) 3.87
DNA demethylation dynamics. Cell (2011) 3.82
Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis. J Clin Invest (2004) 3.53
Stable reprogrammed heterokaryons form spontaneously in Purkinje neurons after bone marrow transplant. Nat Cell Biol (2003) 3.03
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat Chem Biol (2007) 2.80
The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism. Proc Natl Acad Sci U S A (2005) 2.47
Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice. Cell (2010) 2.43
Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation. Nat Cell Biol (2008) 2.30
Contribution of hematopoietic stem cells to skeletal muscle. Nat Med (2003) 2.18
Contribution of transplanted bone marrow cells to Purkinje neurons in human adult brains. Proc Natl Acad Sci U S A (2003) 1.99
Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle. Cell Stem Cell (2010) 1.89
Protein-protein interactions monitored in mammalian cells via complementation of beta -lactamase enzyme fragments. Proc Natl Acad Sci U S A (2002) 1.89
Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium. Arterioscler Thromb Vasc Biol (2008) 1.88
Optimizing techniques for tracking transplanted stem cells in vivo. Stem Cells (2005) 1.80
Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. Circulation (2006) 1.75
Perturbation of single hematopoietic stem cell fates in artificial niches. Integr Biol (Camb) (2008) 1.57
Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation. J Biol Chem (2007) 1.55
Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia. FASEB J (2006) 1.54
Myoblasts and macrophages share molecular components that contribute to cell-cell fusion. J Cell Biol (2008) 1.52
Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons. Proc Natl Acad Sci U S A (2007) 1.40
Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nat Methods (2006) 1.40
Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat Genet (2004) 1.40
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation (2005) 1.35
A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches. Differentiation (2009) 1.29
Significant differences among skeletal muscles in the incorporation of bone marrow-derived cells. Dev Biol (2003) 1.29
Nuclear reprogramming: a key to stem cell function in regenerative medicine. Nat Cell Biol (2004) 1.26
Bone marrow contribution to skeletal muscle: a physiological response to stress. Dev Biol (2005) 1.24
Adenoviral human BCL-2 transgene expression attenuates early donor cell death after cardiomyoblast transplantation into ischemic rat hearts. Circulation (2006) 1.20
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions. Nat Methods (2010) 1.20
A brief history of RNAi: the silence of the genes. FASEB J (2006) 1.19
Gene delivery to muscle. Curr Protoc Hum Genet (2002) 1.19
MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Res (2011) 1.17
Localized arteriole formation directly adjacent to the site of VEGF-induced angiogenesis in muscle. Mol Ther (2003) 1.17
Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. Mol Ther (2013) 1.16
CD34 is a specific marker of mature murine mast cells. Exp Hematol (2002) 1.16
Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class I antigen presentation. J Immunol (2006) 1.14
IGF-I increases bone marrow contribution to adult skeletal muscle and enhances the fusion of myelomonocytic precursors. J Cell Biol (2005) 1.14
Artificial stem cell niches. Adv Mater (2009) 1.11
Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors. Proc Natl Acad Sci U S A (2004) 1.11
Critical role of microenvironmental factors in angiogenesis. Curr Atheroscler Rep (2005) 1.09
Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins. J Immunol (2004) 1.08
Suture techniques for the nasal tip. Aesthet Surg J (2008) 1.07
Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy. Nat Cell Biol (2013) 1.07
Engineering a stem cell house into a home. Stem Cell Res Ther (2011) 1.04
Enzymatic detection of protein translocation. Nat Methods (2005) 1.03
Structure-function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism. Proc Natl Acad Sci U S A (2011) 1.03
Reprogramming to a muscle fate by fusion recapitulates differentiation. J Cell Sci (2009) 0.99
The ANK3 bipolar disorder gene regulates psychiatric-related behaviors that are modulated by lithium and stress. Biol Psychiatry (2012) 0.98
Therapeutic angiogenesis due to balanced single-vector delivery of VEGF and PDGF-BB. FASEB J (2012) 0.96
Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity. Cancer Immunol Immunother (2012) 0.95
Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations. J Cell Sci (2004) 0.95
A twist of fate. Nature (2002) 0.95
Myoblast-mediated gene transfer for therapeutic angiogenesis. Methods Enzymol (2002) 0.95
Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis. Gene Ther (2004) 0.95
eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides. Mol Ther (2005) 0.94
A global increase in 5-hydroxymethylcytosine levels marks osteoarthritic chondrocytes. Arthritis Rheumatol (2014) 0.93
skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. Proc Natl Acad Sci U S A (2010) 0.92
A universal technology for monitoring G-protein-coupled receptor activation in vitro and noninvasively in live animals. FASEB J (2007) 0.92
An immunoreceptor tyrosine-based inhibition motif in varicella-zoster virus glycoprotein B regulates cell fusion and skin pathogenesis. Proc Natl Acad Sci U S A (2013) 0.91
VEGF gene delivery for treatment of ischemic cardiovascular disease. Trends Cardiovasc Med (2002) 0.91
A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells. FASEB J (2012) 0.90
Transient production of alpha-smooth muscle actin by skeletal myoblasts during differentiation in culture and following intramuscular implantation. Cell Motil Cytoskeleton (2002) 0.90
RIP2, a checkpoint in myogenic differentiation. Mol Cell Biol (2002) 0.89
Tumor suppressors: enhancers or suppressors of regeneration? Development (2013) 0.87
A novel enzyme complementation-based assay for monitoring G-protein-coupled receptor internalization. FASEB J (2007) 0.87
Increased host neuronal survival and motor function in BMT Parkinsonian mice: involvement of immunosuppression. J Comp Neurol (2007) 0.87
Comparative potential of juvenile and adult human articular chondrocytes for cartilage tissue formation in three-dimensional biomimetic hydrogels. Tissue Eng Part A (2014) 0.86
Global linking of cell tracks using the viterbi algorithm. IEEE Trans Med Imaging (2014) 0.85
Myoblast-mediated gene transfer for therapeutic angiogenesis and arteriogenesis. Br J Pharmacol (2003) 0.85
Protein-engineered biomaterials to generate human skeletal muscle mimics. Adv Healthc Mater (2012) 0.85
Early role for IL-6 signalling during generation of induced pluripotent stem cells revealed by heterokaryon RNA-Seq. Nat Cell Biol (2013) 0.84
In vivo optical bioluminescence imaging of collagen-supported cardiac cell grafts. J Heart Lung Transplant (2007) 0.83
Localization of vascular response to VEGF is not dependent on heparin binding. FASEB J (2007) 0.83
Collagen VI enhances cartilage tissue generation by stimulating chondrocyte proliferation. Tissue Eng Part A (2014) 0.83
Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation. Proc Natl Acad Sci U S A (2014) 0.81
A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. Integr Biol (Camb) (2012) 0.80
Hepatic parenchymal replacement in mice by transplanted allogeneic hepatocytes is facilitated by bone marrow transplantation and mediated by CD4 cells. Hepatology (2008) 0.79
Imaging beta-galactosidase activity in vivo using sequential reporter-enzyme luminescence. Methods Mol Biol (2009) 0.79
Avian models to study the transcriptional control of hematopoietic lineage commitment and to identify lineage-specific genes. Cells Tissues Organs (2002) 0.79
mRNA translation is not a prerequisite for small interfering RNA-mediated mRNA cleavage. Differentiation (2005) 0.78