Published in Trends Cell Biol on August 31, 2010
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc Natl Acad Sci U S A (2011) 5.45
Distinct DNA methylomes of newborns and centenarians. Proc Natl Acad Sci U S A (2012) 4.26
DNA demethylation dynamics. Cell (2011) 3.82
Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell (2012) 3.65
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol Cell (2011) 2.77
Direct lineage conversions: unnatural but useful? Nat Biotechnol (2011) 2.69
DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell (2012) 2.45
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Calcific aortic valve stenosis: methods, models, and mechanisms. Circ Res (2011) 1.70
Epigenetic disruption of the PIWI pathway in human spermatogenic disorders. PLoS One (2012) 1.64
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes. Proc Natl Acad Sci U S A (2011) 1.51
EpiExplorer: live exploration and global analysis of large epigenomic datasets. Genome Biol (2012) 1.40
Global DNA methylation remodeling accompanies CD8 T cell effector function. J Immunol (2013) 1.27
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier. Philos Trans R Soc Lond B Biol Sci (2013) 1.26
Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer. Am J Pathol (2012) 1.20
DNA synthesis is required for reprogramming mediated by stem cell fusion. Cell (2013) 1.14
Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter. Nucleic Acids Res (2013) 1.10
DNA methylation program during development. Front Biol (Beijing) (2012) 1.07
Interplay between Epigenetics and Genetics in Cancer. Genomics Inform (2013) 1.03
Structural and functional coordination of DNA and histone methylation. Cold Spring Harb Perspect Biol (2014) 0.98
Active DNA demethylation in post-mitotic neurons: a reason for optimism. Neuropharmacology (2013) 0.94
Epigenetic modifications by dietary phytochemicals: implications for personalized nutrition. Pharmacol Ther (2012) 0.92
Epigenomics of cancer - emerging new concepts. Biochimie (2012) 0.90
Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol (2016) 0.90
Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation. Nucleic Acids Res (2011) 0.90
Influence of toxicologically relevant metals on human epigenetic regulation. Toxicol Res (2015) 0.89
Epigenetic control on cell fate choice in neural stem cells. Protein Cell (2012) 0.87
Hsa-miR-520d induces hepatoma cells to form normal liver tissues via a stemness-mediated process. Sci Rep (2014) 0.87
Cellular reprogramming and hepatocellular carcinoma development. World J Gastroenterol (2013) 0.86
Epigenetic reprogramming modulates malignant properties of human liver cancer. Hepatology (2014) 0.86
Non-viral expression of mouse Oct4, Sox2, and Klf4 transcription factors efficiently reprograms tadpole muscle fibers in vivo. J Biol Chem (2012) 0.85
Environmental alterations of epigenetics prior to the birth. Int Rev Neurobiol (2014) 0.85
Conserved Epigenetic Mechanisms Could Play a Key Role in Regulation of Photosynthesis and Development-Related Genes during Needle Development of Pinus radiata. PLoS One (2015) 0.83
Changes in DNA methylation are associated with the development of drug resistance in cervical cancer cells. Cancer Cell Int (2015) 0.82
Orchestrating the Tumor Microenvironment to Improve Survival for Patients With Pancreatic Cancer: Normalization, Not Destruction. Cancer J (2015) 0.81
Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth. Mol Cancer (2011) 0.80
Gender-specific DNA methylome analysis of a Han Chinese longevity population. Biomed Res Int (2014) 0.79
Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors. Cell Regen (Lond) (2014) 0.79
PD-L1 promoter methylation is a prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients following radical prostatectomy. Oncotarget (2016) 0.79
Epigenetic management of major psychosis. Clin Epigenetics (2011) 0.79
DNA methyltransferase inhibition accelerates the immunomodulation and migration of human mesenchymal stem cells. Sci Rep (2015) 0.78
Higher methylation in genomic DNA indicates incomplete reprogramming in induced pluripotent stem cells. Cell Reprogram (2013) 0.78
Epigenetic regulation of sox30 is associated with testis development in mice. PLoS One (2014) 0.78
Emulsion electrospun nanofibers as substrates for cardiomyogenic differentiation of mesenchymal stem cells. J Mater Sci Mater Med (2013) 0.78
Emerging technologies for studying DNA methylation for the molecular diagnosis of cancer. Expert Rev Mol Diagn (2015) 0.77
Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison. Sci Rep (2015) 0.77
Epigenetic modifications of caveolae associated proteins in health and disease. BMC Genet (2015) 0.77
Delayed self-regulation and time-dependent chemical drive leads to novel states in epigenetic landscapes. J R Soc Interface (2014) 0.77
Cell-based therapies of liver diseases: age-related challenges. Clin Interv Aging (2015) 0.77
Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells. Oncotarget (2015) 0.76
Hsa-miR-520d converts fibroblasts into CD105+ populations. Drugs R D (2014) 0.76
Gadd45b and N-methyl-D-aspartate induced DNA demethylation in postmitotic neurons. Epigenomics (2015) 0.76
DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract. PLoS One (2016) 0.76
Uncovering Driver DNA Methylation Events in Nonsmoking Early Stage Lung Adenocarcinoma. Biomed Res Int (2016) 0.75
Retracted Regulatory factors of induced pluripotency: current status. Stem Cell Investig (2014) 0.75
DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells. Stem Cells Int (2014) 0.75
Cytogenetic effect of 5-azacytidine in patients with hematological malignancies. Rev Bras Hematol Hemoter (2011) 0.75
Anticancer Natural Compounds as Epigenetic Modulators of Gene Expression. Curr Genomics (2017) 0.75
Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells. Genes Dev (2017) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (2009) 32.97
Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77
The epigenomics of cancer. Cell (2007) 30.91
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature (2007) 28.24
Viable offspring derived from fetal and adult mammalian cells. Nature (1997) 22.46
Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell (1987) 22.17
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol (2007) 21.93
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell (2007) 21.58
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature (2010) 18.63
Dissecting direct reprogramming through integrative genomic analysis. Nature (2008) 16.47
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature (2008) 16.21
Generation of mouse induced pluripotent stem cells without viral vectors. Science (2008) 15.25
Epigenetic memory in induced pluripotent stem cells. Nature (2010) 14.31
Induced pluripotent stem cells generated without viral integration. Science (2008) 13.38
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell (2008) 12.45
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (2007) 12.41
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell (2009) 11.65
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol (2008) 10.97
Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet (2010) 10.71
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell (2008) 10.68
Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol (2008) 10.63
Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science (2008) 10.55
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
Histone demethylation by a family of JmjC domain-containing proteins. Nature (2005) 10.36
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature (2009) 9.75
Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature (2009) 9.29
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol (2007) 9.04
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature (2010) 8.84
Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature (2009) 8.70
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell (2008) 8.62
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
The colorful history of active DNA demethylation. Cell (2008) 8.50
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature (2009) 7.96
A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol (2008) 7.95
Stepwise reprogramming of B cells into macrophages. Cell (2004) 7.68
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci U S A (2008) 7.52
The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature (2009) 7.39
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature (2008) 7.07
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature (2010) 7.05
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature (2009) 6.85
JmjC-domain-containing proteins and histone demethylation. Nat Rev Genet (2006) 6.65
Oct4-induced pluripotency in adult neural stem cells. Cell (2009) 6.50
Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature (2010) 6.20
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res (2010) 6.03
A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell (2008) 5.90
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell (2009) 5.49
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature (2009) 5.37
Nuclear reprogramming to a pluripotent state by three approaches. Nature (2010) 5.26
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol (2006) 5.16
Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet (2007) 5.16
Epigenetic reprogramming and induced pluripotency. Development (2009) 4.90
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem (2004) 4.86
Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression. Stem Cells (2008) 4.67
A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell (2009) 4.64
Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc Natl Acad Sci U S A (2008) 4.48
Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell (2009) 4.38
Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science (2010) 4.32
Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Nat Genet (2009) 4.28
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc Natl Acad Sci U S A (2008) 4.20
Rethinking how DNA methylation patterns are maintained. Nat Rev Genet (2009) 4.03
DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei. Nat Cell Biol (2004) 3.89
Active DNA demethylation mediated by DNA glycosylases. Annu Rev Genet (2009) 3.66
Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells (2010) 3.53
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes. Nat Struct Mol Biol (2008) 3.33
Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell (2008) 3.31
Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev (2004) 2.75
Induced pluripotent stem cells: current progress and potential for regenerative medicine. Trends Mol Med (2009) 2.57
Moving AHEAD with an international human epigenome project. Nature (2008) 2.38
Defined factors induce reprogramming of gastrointestinal cancer cells. Proc Natl Acad Sci U S A (2009) 2.11
Balancing AID and DNA repair during somatic hypermutation. Trends Immunol (2009) 1.86
Periodic activation of Wnt/beta-catenin signaling enhances somatic cell reprogramming mediated by cell fusion. Cell Stem Cell (2008) 1.78
A coming-of-age story: activation-induced cytidine deaminase turns 10. Nat Immunol (2009) 1.68
Reprogramming cell differentiation in the absence of DNA synthesis. Cell (1984) 1.66
5-Azacytidine permits gene activation in a previously noninducible cell type. Cell (1985) 1.64
Resetting the epigenome beyond pluripotency in the germline. Cell Stem Cell (2009) 1.35
Nuclear reprogramming in heterokaryons is rapid, extensive, and bidirectional. FASEB J (2009) 1.31
Human iPS cell-based therapy: considerations before clinical applications. Cell Cycle (2010) 1.29
Aberrant epigenetic silencing of tumor suppressor genes is reversed by direct reprogramming. Stem Cells (2010) 0.89
Direct generation of ES-like cells from unmodified mouse embryonic fibroblasts by Oct4/Sox2/Myc/Klf4. Cell Res (2007) 0.87
Therapeutic cloning in the mouse. Proc Natl Acad Sci U S A (2003) 0.86
Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A (2002) 12.33
Epigenetics in human disease and prospects for epigenetic therapy. Nature (2004) 11.46
A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer (2011) 11.33
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell (2006) 8.46
Epigenetics in cancer. Carcinogenesis (2009) 7.49
Epigenetic therapy of cancer: past, present and future. Nat Rev Drug Discov (2006) 6.39
Cancer epigenetics: modifications, screening, and therapy. Annu Rev Med (2008) 4.41
Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome. Proc Natl Acad Sci U S A (2004) 4.39
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc Natl Acad Sci U S A (2008) 4.20
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. Blood (2002) 3.89
Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell (2012) 3.65
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol (2002) 3.61
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Mol Cancer Ther (2009) 3.56
The CpG island searcher: a new WWW resource. In Silico Biol (2003) 3.42
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen. Cancer Res (2004) 3.23
Epigenetic modifications as therapeutic targets. Nat Biotechnol (2010) 3.16
Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island. Cancer Cell (2007) 3.15
DNA methylation and breast carcinogenesis. Oncogene (2002) 3.03
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. Cancer Res (2002) 3.02
DNA methylation: the nuts and bolts of repression. J Cell Physiol (2007) 3.00
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res (2009) 2.83
Epigenetics and microRNAs. Pediatr Res (2007) 2.52
DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell (2012) 2.45
Preferential response of cancer cells to zebularine. Cancer Cell (2004) 2.39
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol Cell Biol (2009) 2.34
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. PLoS Genet (2010) 2.27
Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proc Natl Acad Sci U S A (2006) 2.25
Inhibition of DNA methylation and reactivation of silenced genes by zebularine. J Natl Cancer Inst (2003) 2.22
Polycomb-repressed genes have permissive enhancers that initiate reprogramming. Cell (2011) 2.14
p53 gene and protein status: the role of p53 alterations in predicting outcome in patients with bladder cancer. J Clin Oncol (2007) 2.14
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prev Res (Phila) (2008) 2.04
Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Cell Cycle (2006) 1.98
Epigenetic changes in cancer. APMIS (2007) 1.96
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules. Genome Res (2012) 1.95
Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level. Nucleic Acids Res (2005) 1.94
H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes. Mol Cell (2010) 1.85
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. Mol Cancer Ther (2005) 1.85
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter. Hum Mol Genet (2011) 1.83
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. Cancer Res (2002) 1.71
Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients. Clin Cancer Res (2004) 1.69
Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation. Mol Cancer Res (2004) 1.68
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Mol Cell Biol (2004) 1.68
Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Res (2003) 1.62
Targeting DNA methylation for epigenetic therapy. Trends Pharmacol Sci (2010) 1.61
Preoperative sentinel node identification with ultrasound using microbubbles in patients with breast cancer. AJR Am J Roentgenol (2011) 1.58
Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. PLoS Genet (2011) 1.56
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes. Proc Natl Acad Sci U S A (2011) 1.51
Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting. PLoS Genet (2006) 1.48
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers. Oncotarget (2014) 1.47
Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue. Cancer Res (2010) 1.47
Locus-wide chromatin remodeling and enhanced androgen receptor-mediated transcription in recurrent prostate tumor cells. Mol Cell Biol (2006) 1.46
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine. Oncotarget (2013) 1.44
MicroRNAs: critical mediators of differentiation, development and disease. Swiss Med Wkly (2009) 1.43
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight. Nucleic Acids Res (2008) 1.42
Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer. Nat Clin Pract Urol (2005) 1.41
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer Res (2007) 1.40
Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment. Cancer Res (2007) 1.40
Emergency Department utilisation: a natural experiment. N Z Med J (2009) 1.39
Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells. Mol Cell Biol (2011) 1.34
Cell division is required for de novo methylation of CpG islands in bladder cancer cells. Cancer Res (2002) 1.32
DNA methylation and cancer. Prog Drug Res (2011) 1.24
Chromatin, cancer and drug therapies. Mutat Res (2008) 1.21
Origins of bidirectional promoters: computational analyses of intergenic distance in the human genome. Mol Biol Evol (2003) 1.20
Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma. Eur J Cancer (2005) 1.18
Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML. Blood (2011) 1.17
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Res (2013) 1.12
Discovery of epigenetically masked tumor suppressor genes in endometrial cancer. Mol Cancer Res (2005) 1.12
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. Ann N Y Acad Sci (2005) 1.11
Functional DNA demethylation is accompanied by chromatin accessibility. Nucleic Acids Res (2013) 1.09
Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions. PLoS Genet (2012) 1.07
Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome. PLoS One (2010) 1.07
Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF. Nucleic Acids Res (2009) 1.07
Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms-SNuPE). Methods (2002) 1.06
Identification of DNA methylation differences during tumorigenesis by methylation-sensitive arbitrarily primed polymerase chain reaction. Methods (2002) 1.06
RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking. Cancer Res (2008) 1.05
Identification and characterization of alternatively spliced variants of DNA methyltransferase 3a in mammalian cells. Gene (2002) 1.04
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology. Nucleosides Nucleotides Nucleic Acids (2005) 0.99
A panel of three markers hyper- and hypomethylated in urine sediments accurately predicts bladder cancer recurrence. Clin Cancer Res (2014) 0.99
The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer. Cell Cycle (2009) 0.94
S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. Mol Cancer Ther (2010) 0.94
Hyperphosphorylation of pRb: a mechanism for RB tumour suppressor pathway inactivation in bladder cancer. J Pathol (2004) 0.94
At the tipping point for epigenetic therapies in cancer. J Clin Invest (2014) 0.94
Preoperative needle biopsy of sentinel lymph nodes using intradermal microbubbles and contrast-enhanced ultrasound in patients with breast cancer. AJR Am J Roentgenol (2012) 0.93
Methylation-sensitive single-molecule analysis of chromatin structure. Curr Protoc Mol Biol (2010) 0.93
Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation. Transl Oncol (2009) 0.91
Diagnostic markers of urothelial cancer based on DNA methylation analysis. BMC Cancer (2013) 0.90
Reversine increases the plasticity of lineage-committed cells toward neuroectodermal lineage. J Biol Chem (2008) 0.87
SNF5 is an essential executor of epigenetic regulation during differentiation. PLoS Genet (2013) 0.87
A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. Cancer Res (2012) 0.87
Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. Epigenetics (2011) 0.86
Meddling with methylation. Nat Cell Biol (2003) 0.86
Radiopaque coil insertion into breast cancers prior to neoadjuvant chemotherapy. Breast (2005) 0.86
Patch clamp recording from enteric neurons in situ. Nat Protoc (2011) 0.82
Reprogramming of the human intestinal epigenome by surgical tissue transposition. Genome Res (2014) 0.80
Epigenetic activation of the Foxa2 gene is required for maintaining the potential of neural precursor cells to differentiate into dopaminergic neurons after expansion. Stem Cells Dev (2014) 0.79