Published in Cell Host Microbe on January 22, 2009
Helicobacter pylori: gastric cancer and beyond. Nat Rev Cancer (2010) 4.64
Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev (2010) 3.41
Mechanisms of disease: Helicobacter pylori virulence factors. Nat Rev Gastroenterol Hepatol (2010) 2.56
Helicobacter pylori from Peruvian amerindians: traces of human migrations in strains from remote Amazon, and genome sequence of an Amerind strain. PLoS One (2010) 1.48
Vibrio cholerae T3SS effector VopE modulates mitochondrial dynamics and innate immune signaling by targeting Miro GTPases. Cell Host Microbe (2014) 1.47
Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells. Gastroenterology (2010) 1.45
Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells. PLoS Pathog (2009) 1.40
Association between Helicobacter pylori virulence factors and gastroduodenal diseases in Okinawa, Japan. J Clin Microbiol (2011) 1.37
BabA-mediated adherence is a potentiator of the Helicobacter pylori type IV secretion system activity. J Biol Chem (2011) 1.33
Biochemical and functional characterization of Helicobacter pylori vesicles. Mol Microbiol (2010) 1.18
Pathobiology of Helicobacter pylori-Induced Gastric Cancer. Gastroenterology (2015) 1.13
Helicobacter pylori in gastric carcinogenesis: mechanisms. Gastroenterol Clin North Am (2013) 1.11
Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review. World J Exp Med (2015) 1.10
Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses. J Bacteriol (2010) 1.10
β-Catenin and p120 mediate PPARδ-dependent proliferation induced by Helicobacter pylori in human and rodent epithelia. Gastroenterology (2011) 1.08
Attenuated CagA oncoprotein in Helicobacter pylori from Amerindians in Peruvian Amazon. J Biol Chem (2011) 1.06
Role of the Helicobacter pylori-induced inflammatory response in the development of gastric cancer. J Cell Biochem (2013) 1.02
Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection. Nat Commun (2014) 1.01
A Tale of Two Toxins: Helicobacter Pylori CagA and VacA Modulate Host Pathways that Impact Disease. Front Microbiol (2010) 1.00
How Helicobacter pylori infection controls gastric acid secretion. J Gastroenterol (2012) 0.99
Evolution of cagA oncogene of Helicobacter pylori through recombination. PLoS One (2011) 0.98
Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled. Mol Cancer (2010) 0.97
CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation. PLoS Pathog (2015) 0.96
Helicobacter, Inflammation, and Gastric Cancer. Curr Pathobiol Rep (2013) 0.94
Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation. Oncogene (2012) 0.93
Gastric microbiome and gastric cancer. Cancer J (2014) 0.93
Variations in Helicobacter pylori cytotoxin-associated genes and their influence in progression to gastric cancer: implications for prevention. PLoS One (2012) 0.92
Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathways. Cell Commun Signal (2015) 0.92
"Targeted disruption of the epithelial-barrier by Helicobacter pylori". Cell Commun Signal (2011) 0.92
Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine. Front Immunol (2013) 0.91
A novel inhibitory domain of Helicobacter pylori protein CagA reduces CagA effects on host cell biology. J Biol Chem (2011) 0.91
DNA methylation in gastric cancer, related to Helicobacter pylori and Epstein-Barr virus. World J Gastroenterol (2014) 0.91
H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model. Dis Model Mech (2013) 0.90
J-Western forms of Helicobacter pylori cagA constitute a distinct phylogenetic group with a widespread geographic distribution. J Bacteriol (2012) 0.90
Helicobacter pylori--a seasoned pathogen by any other name. Gut Pathog (2009) 0.90
Helicobacter pylori colonization ameliorates glucose homeostasis in mice through a PPAR γ-dependent mechanism. PLoS One (2012) 0.90
Molecular cross-talk between Helicobacter pylori and human gastric mucosa. World J Gastroenterol (2011) 0.90
Wnt/β-catenin, an oncogenic pathway targeted by H. pylori in gastric carcinogenesis. Oncotarget (2015) 0.89
Polymorphism in the Helicobacter pylori CagA and VacA toxins and disease. Gut Microbes (2013) 0.89
Signal transduction of Helicobacter pylori during interaction with host cell protein receptors of epithelial and immune cells. Gut Microbes (2013) 0.89
A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions. PLoS Pathog (2015) 0.88
Helicobacter pylori Diversity and Gastric Cancer Risk. MBio (2016) 0.88
Disruption of nitric oxide signaling by Helicobacter pylori results in enhanced inflammation by inhibition of heme oxygenase-1. J Immunol (2011) 0.87
Enteric bacteria and cancer stem cells. Cancers (Basel) (2010) 0.87
Study of the cytoxin-associated gene a (CagA gene) in Helicobacter pylori using gastric biopsies of Iraqi patients. Saudi J Gastroenterol (2013) 0.86
Factors that mediate colonization of the human stomach by Helicobacter pylori. World J Gastroenterol (2014) 0.86
The Helicobacter pylori cag Pathogenicity Island. Methods Mol Biol (2012) 0.86
SNP interactions of Helicobacter pylori-related host genes PGC, PTPN11, IL1B, and TLR4 in susceptibility to gastric carcinogenesis. Oncotarget (2015) 0.85
Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori. Proc Natl Acad Sci U S A (2009) 0.84
Haem oxygenase-1 inhibits phosphorylation of the Helicobacter pylori oncoprotein CagA in gastric epithelial cells. Cell Microbiol (2012) 0.84
Gastrokine 1 inhibits the carcinogenic potentials of Helicobacter pylori CagA. Carcinogenesis (2014) 0.83
Microbiome, inflammation, and cancer. Cancer J (2014) 0.82
Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer. Nat Rev Microbiol (2017) 0.81
The ferric uptake regulator of Helicobacter pylori: a critical player in the battle for iron and colonization of the stomach. Future Microbiol (2013) 0.81
Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway. Oncotarget (2015) 0.80
Human gastrin mRNA expression up-regulated by Helicobacter pylori CagA through MEK/ERK and JAK2-signaling pathways in gastric cancer cells. Gastric Cancer (2011) 0.80
Conformational analysis of isolated domains of Helicobacter pylori CagA. PLoS One (2013) 0.80
Gene expression profiling in gastric mucosa from Helicobacter pylori-infected and uninfected patients undergoing chronic superficial gastritis. PLoS One (2012) 0.80
p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis? Oncotarget (2016) 0.79
Potential of known and short prokaryotic protein motifs as a basis for novel peptide-based antibacterial therapeutics: a computational survey. Front Microbiol (2014) 0.79
The EPIYA-ABCC motif pattern in CagA of Helicobacter pylori is associated with peptic ulcer and gastric cancer in Mexican population. BMC Gastroenterol (2014) 0.79
Helicobacter pylori induces NF-kappaB independent of CagA. EMBO Rep (2010) 0.79
Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein. Sci Rep (2015) 0.79
Effect of Helicobacter pylori Infection on the Composition of Gastric Microbiota in the Development of Gastric Cancer. Gastrointest Tumors (2015) 0.78
Dynamic Expansion and Contraction of cagA Copy Number in Helicobacter pylori Impact Development of Gastric Disease. MBio (2017) 0.78
Helicobacter pylori protein JHP0290 exhibits proliferative and anti-apoptotic effects in gastric epithelial cells. PLoS One (2015) 0.78
Presence of terminal EPIYA phosphorylation motifs in Helicobacter pylori CagA contributes to IL-8 secretion, irrespective of the number of repeats. PLoS One (2013) 0.78
Helicobacter pylori CagA: a critical destroyer of the gastric epithelial barrier. Dig Dis Sci (2013) 0.78
Crosstalks between cytokines and Sonic Hedgehog in Helicobacter pylori infection: a mathematical model. PLoS One (2014) 0.77
Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise. Free Radic Biol Med (2016) 0.76
Helicobacter pylori CagA Suppresses Apoptosis through Activation of AKT in a Nontransformed Epithelial Cell Model of Glandular Acini Formation. Biomed Res Int (2015) 0.76
Impact of Helicobacter pylori on the healing process of the gastric barrier. World J Gastroenterol (2016) 0.76
Helicobacter pylori and microRNAs: Relation with innate immunity and progression of preneoplastic conditions. World J Clin Oncol (2015) 0.75
Molecular mechanisms of gastric cancer initiation and progression by Helicobacter pylori. Curr Opin Infect Dis (2016) 0.75
Helicobacter pylori CagA induced interleukin-8 secretion in gastric epithelial cells. Gastroenterol Hepatol Bed Bench (2016) 0.75
Initiation and Maintenance of Gastric Cancer: A Focus on CD44 Variant Isoforms and Cancer Stem Cells. Cell Mol Gastroenterol Hepatol (2017) 0.75
Association of smoking, alcohol and NSAIDs use with expression of cag A and cag T genes of Helicobacter pylori in salivary samples of asymptomatic subjects. Asian Pac J Trop Biomed (2012) 0.75
Human and Helicobacter pylori Interactions Determine the Outcome of Gastric Diseases. Curr Top Microbiol Immunol (2017) 0.75
Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1α to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells. Front Cell Infect Microbiol (2017) 0.75
The Role of H. pylori CagA in Regulating Hormones of Functional Dyspepsia Patients. Gastroenterol Res Pract (2016) 0.75
MET4 Expression Predicts Poor Prognosis of Gastric Cancers with Helicobacter pylori Infection. Cancer Sci (2016) 0.75
Association of CagA EPIYA-D or EPIYA-C phosphorylation sites with peptic ulcer and gastric cancer risks: A meta-analysis. Medicine (Baltimore) (2017) 0.75
Helicobacter pylori inhibits the cleavage of TRAF1 via a CagA-dependent mechanism. World J Gastroenterol (2016) 0.75
Lactobacillus paracasei strain 06TCa19 suppresses inflammatory chemokine induced by Helicobacter pylori in human gastric epithelial cells. Hum Cell (2017) 0.75
Helicobacter pylori CagA Protein Negatively Regulates Autophagy and Promotes Inflammatory Response via c-Met-PI3K/Akt-mTOR Signaling Pathway. Front Cell Infect Microbiol (2017) 0.75
Structure and function of Helicobacter pylori CagA, the first-identified bacterial protein involved in human cancer. Proc Jpn Acad Ser B Phys Biol Sci (2017) 0.75
Binding of the Helicobacter pylori OipA causes apoptosis of host cells via modulation of Bax/Bcl-2 levels. Sci Rep (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis (2003) 15.02
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature (2003) 9.79
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature (2009) 9.71
Microscopic-observation drug-susceptibility assay for the diagnosis of TB. N Engl J Med (2006) 8.39
Innate lymphoid cells--a proposal for uniform nomenclature. Nat Rev Immunol (2013) 7.94
Escape of intracellular Shigella from autophagy. Science (2004) 6.64
A promoter-level mammalian expression atlas. Nature (2014) 6.25
Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity (2009) 6.24
Taenia solium cysticercosis. Lancet (2003) 5.89
A trial of antiparasitic treatment to reduce the rate of seizures due to cerebral cysticercosis. N Engl J Med (2004) 5.75
Evaluation and treatment of chagas disease in the United States: a systematic review. JAMA (2007) 5.22
Human brucellosis. Lancet Infect Dis (2007) 4.92
Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study. Lancet (2002) 4.90
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog (2007) 4.73
Multi-country analysis of the effects of diarrhoea on childhood stunting. Int J Epidemiol (2008) 4.46
Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation. Science (2002) 4.38
Effect of water and sanitation on childhood health in a poor Peruvian peri-urban community. Lancet (2004) 4.36
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat Immunol (2005) 4.32
Natural ventilation for the prevention of airborne contagion. PLoS Med (2007) 3.73
The effect of deforestation on the human-biting rate of Anopheles darlingi, the primary vector of Falciparum malaria in the Peruvian Amazon. Am J Trop Med Hyg (2006) 3.72
PI3K and negative regulation of TLR signaling. Trends Immunol (2003) 3.70
Prevention and control of cystic echinococcosis. Lancet Infect Dis (2007) 3.64
PI3K-mediated negative feedback regulation of IL-12 production in DCs. Nat Immunol (2002) 3.37
Current consensus guidelines for treatment of neurocysticercosis. Clin Microbiol Rev (2002) 3.37
An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling. Cell (2007) 3.34
Microscopic observation drug susceptibility assay, a rapid, reliable diagnostic test for multidrug-resistant tuberculosis suitable for use in resource-poor settings. J Clin Microbiol (2004) 3.27
Mutation discovery in bacterial genomes: metronidazole resistance in Helicobacter pylori. Nat Methods (2005) 3.19
Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science (2004) 3.06
Listeria monocytogenes ActA-mediated escape from autophagic recognition. Nat Cell Biol (2009) 3.05
Perilesional brain oedema and seizure activity in patients with calcified neurocysticercosis: a prospective cohort and nested case-control study. Lancet Neurol (2008) 3.04
Grb2 is a key mediator of helicobacter pylori CagA protein activities. Mol Cell (2002) 2.80
Clinical spectrum of pulmonary involvement in leptospirosis in a region of endemicity, with quantification of leptospiral burden. Clin Infect Dis (2005) 2.75
Intestinal villous M cells: an antigen entry site in the mucosal epithelium. Proc Natl Acad Sci U S A (2004) 2.75
Diagnostic approaches for paediatric tuberculosis by use of different specimen types, culture methods, and PCR: a prospective case-control study. Lancet Infect Dis (2010) 2.69
Linking deforestation to malaria in the Amazon: characterization of the breeding habitat of the principal malaria vector, Anopheles darlingi. Am J Trop Med Hyg (2009) 2.64
Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells. Blood (2008) 2.53
Triosephosphate isomerase gene characterization and potential zoonotic transmission of Giardia duodenalis. Emerg Infect Dis (2003) 2.46
Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis. Proc Natl Acad Sci U S A (2007) 2.44
Endemic malaria in the Peruvian Amazon region of Iquitos. Am J Trop Med Hyg (2003) 2.43
Species identification after treatment for human taeniasis. Lancet (2004) 2.43
Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach. Cell Host Microbe (2007) 2.41
Multiple norovirus infections in a birth cohort in a Peruvian Periurban community. Clin Infect Dis (2013) 2.37
Shigella targets epithelial tricellular junctions and uses a noncanonical clathrin-dependent endocytic pathway to spread between cells. Cell Host Microbe (2012) 2.30
The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model. Clin Infect Dis (2007) 2.28
Prolonged infectiousness of tuberculosis patients in a directly observed therapy short-course program with standardized therapy. Clin Infect Dis (2010) 2.11
Neurocysticercosis: A natural human model of epileptogenesis. Epilepsia (2014) 2.11
New concepts in the diagnosis and management of neurocysticercosis (Taenia solium). Am J Trop Med Hyg (2005) 2.10
The infectiousness of tuberculosis patients coinfected with HIV. PLoS Med (2008) 2.08
Detection of Taenia solium antigens and anti-T. solium antibodies in paired serum and cerebrospinal fluid samples from patients with intraparenchymal or extraparenchymal neurocysticercosis. J Infect Dis (2009) 2.06
Tuberculosis mortality, drug resistance, and infectiousness in patients with and without HIV infection in Peru. Am J Trop Med Hyg (2006) 2.05
Can the power of mobile phones be used to improve tuberculosis diagnosis in developing countries? Trans R Soc Trop Med Hyg (2008) 2.01
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response. Nature (2012) 1.99
Cryptosporidium species and subtypes and clinical manifestations in children, Peru. Emerg Infect Dis (2008) 1.96
Environmental exposure and leptospirosis, Peru. Emerg Infect Dis (2004) 1.96
Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes. Circ Res (2003) 1.96
Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice. Nat Immunol (2002) 1.92
Determining risk for severe leptospirosis by molecular analysis of environmental surface waters for pathogenic Leptospira. PLoS Med (2006) 1.92
Effects of acute diarrhea on linear growth in Peruvian children. Am J Epidemiol (2003) 1.90
IL-15 regulates CD8+ T cell contraction during primary infection. J Immunol (2006) 1.88
Human leptospirosis caused by a new, antigenically unique Leptospira associated with a Rattus species reservoir in the Peruvian Amazon. PLoS Negl Trop Dis (2008) 1.87
Periurban Trypanosoma cruzi-infected Triatoma infestans, Arequipa, Peru. Emerg Infect Dis (2006) 1.85
Microtubule-severing activity of Shigella is pivotal for intercellular spreading. Science (2006) 1.85
Enzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori. Antimicrob Agents Chemother (2002) 1.84
Congenital Trypanosoma cruzi transmission in Santa Cruz, Bolivia. Clin Infect Dis (2009) 1.81
Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. J Immunol (2003) 1.80
Improved recovery of Mycobacterium tuberculosis from children using the microscopic observation drug susceptibility method. Pediatrics (2006) 1.74
Fecal contamination of drinking water within peri-urban households, Lima, Peru. Am J Trop Med Hyg (2007) 1.72
Metastability of Helicobacter pylori bab adhesin genes and dynamics in Lewis b antigen binding. Proc Natl Acad Sci U S A (2004) 1.71
Cell death and infection: a double-edged sword for host and pathogen survival. J Cell Biol (2011) 1.69
PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ. Cell Rep (2012) 1.67
Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis. Proc Natl Acad Sci U S A (2010) 1.67
Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion. J Exp Med (2005) 1.66
Inducible expression of microRNA-194 is regulated by HNF-1alpha during intestinal epithelial cell differentiation. RNA (2008) 1.66
Epilepsy and neurocysticercosis in Atahualpa: a door-to-door survey in rural coastal Ecuador. Epilepsia (2005) 1.65
Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery. Nat Cell Biol (2006) 1.64
Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmission. PLoS Med (2009) 1.64
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1. EMBO J (2004) 1.64
Transposable element ISHp608 of Helicobacter pylori: nonrandom geographic distribution, functional organization, and insertion specificity. J Bacteriol (2002) 1.60