Published in J Org Chem on March 06, 2009
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Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet (2007) 15.46
Hypothalamic regulation of sleep and circadian rhythms. Nature (2005) 8.23
Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet (2009) 6.35
Altered microRNA expression in human heart disease. Physiol Genomics (2007) 5.64
Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev (2009) 5.21
Sleep state switching. Neuron (2010) 4.94
From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid Redox Signal (2007) 3.49
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology (2003) 3.19
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A (2008) 3.13
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A (2008) 3.10
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc Natl Acad Sci U S A (2007) 3.00
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General acid catalysis by the hepatitis delta virus ribozyme. Nat Chem Biol (2005) 2.88
Pathway level analysis of gene expression using singular value decomposition. BMC Bioinformatics (2005) 2.78
A broad role for melanopsin in nonvisual photoreception. J Neurosci (2003) 2.78
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The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models. Inflamm Bowel Dis (2014) 2.46
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev (2009) 2.41
Differential rescue of light- and food-entrainable circadian rhythms. Science (2008) 2.20
MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol (2009) 2.18
Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci (2003) 2.15
Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization. Blood (2009) 2.11
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The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity (2010) 2.02
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New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes. Genesis (2002) 1.80
Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus. Chem Biol (2011) 1.80
Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics. Sci Transl Med (2012) 1.80
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The relationship between PTH and 25-hydroxy vitamin D early in pregnancy. Clin Endocrinol (Oxf) (2011) 1.56
Human multipotent stromal cells from bone marrow and microRNA: regulation of differentiation and leukemia inhibitory factor expression. Proc Natl Acad Sci U S A (2008) 1.54
Structural inference of native and partially folded RNA by high-throughput contact mapping. Proc Natl Acad Sci U S A (2008) 1.54
New strategies for exploring RNA's 2'-OH expose the importance of solvent during group II intron catalysis. Chem Biol (2004) 1.53
Synthetic antibodies for specific recognition and crystallization of structured RNA. Proc Natl Acad Sci U S A (2007) 1.51
SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression. Cancer Res (2012) 1.50
A hierarchical model for estimating response time distributions. Psychon Bull Rev (2005) 1.50
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nat Commun (2012) 1.49
The effect of repeated etomidate anesthesia on adrenocortical function during a course of electroconvulsive therapy. J ECT (2011) 1.49
Exogenous surfactant may improve oxygenation but not mortality in adult patients with acute lung injury/acute respiratory distress syndrome: a meta-analysis of 9 clinical trials. J Cardiothorac Vasc Anesth (2012) 1.47
Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity. J Biol Chem (2008) 1.45
Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. Ann Thorac Surg (2007) 1.44
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat Commun (2013) 1.43
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An introduction to Bayesian hierarchical models with an application in the theory of signal detection. Psychon Bull Rev (2005) 1.42
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Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis. PLoS One (2011) 1.41
Structure and function of the interacting domains of Spire and Fmn-family formins. Proc Natl Acad Sci U S A (2011) 1.36
Intensity-modulated radiation therapy in the salvage of locally recurrent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys (2011) 1.33
Chemical enhancement of torsinA function in cell and animal models of torsion dystonia. Dis Model Mech (2010) 1.33
Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest (2010) 1.33
Basal ganglia control of sleep-wake behavior and cortical activation. Eur J Neurosci (2010) 1.32
Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. Cell (2010) 1.31
A second divalent metal ion in the group II intron reaction center. Chem Biol (2007) 1.29
Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science (2009) 1.27
The electrostatic character of the ribosomal surface enables extraordinarily rapid target location by ribotoxins. Nat Struct Mol Biol (2006) 1.26
HDAC inhibitors: a potential new category of anti-tumor agents. Cell Mol Immunol (2007) 1.25
The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Mol Cell Biol (2006) 1.25
Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. Eur Heart J (2012) 1.24
The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing. Mol Cell (2010) 1.23
FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells. Breast Cancer Res Treat (2011) 1.22
SOX7, down-regulated in colorectal cancer, induces apoptosis and inhibits proliferation of colorectal cancer cells. Cancer Lett (2008) 1.22
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NMR analysis of the closed conformation of syntaxin-1. J Biomol NMR (2008) 1.19
NEDD9 is a positive regulator of epithelial-mesenchymal transition and promotes invasion in aggressive breast cancer. PLoS One (2011) 1.19
A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination. Nat Struct Mol Biol (2010) 1.18
Identification of catalytic metal ion ligands in ribozymes. Methods (2009) 1.18
Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme. Proc Natl Acad Sci U S A (2010) 1.18
A cocrystal strategy to tune the luminescent properties of stilbene-type organic solid-state materials. Angew Chem Int Ed Engl (2011) 1.18
Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells. BMC Cancer (2012) 1.17
Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific. Mol Pharmacol (2002) 1.16
Role of gut-brain axis in persistent abnormal feeding behavior in mice following eradication of Helicobacter pylori infection. Am J Physiol Regul Integr Comp Physiol (2009) 1.15
Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression. Proc Natl Acad Sci U S A (2006) 1.14
Electrophysiology of human cardiac atrial and ventricular telocytes. J Cell Mol Med (2014) 1.14
Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors. J Exp Biol (2005) 1.14
Unfolding the pathophysiological role of bioactive lysophospholipids. Curr Drug Targets Immune Endocr Metabol Disord (2003) 1.13
MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells. PLoS One (2011) 1.12
Role of Basal Ganglia in sleep-wake regulation: neural circuitry and clinical significance. Front Neuroanat (2010) 1.12