Published in Int J Biochem Cell Biol on June 22, 2010
Differential Gene Expression and Infection Profiles of Cutaneous and Mucosal Leishmania braziliensis Isolates from the Same Patient. PLoS Negl Trop Dis (2015) 0.84
Genome-wide analysis of peptidase content and expression in a virulent and attenuated Babesia bovis strain pair. Mol Biochem Parasitol (2011) 0.80
The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64
Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet (2007) 4.58
Leishmaniasis: drugs in the clinic, resistance and new developments. Drug Resist Updat (2004) 1.96
Developmental regulation of gene expression in trypanosomatid parasitic protozoa. Curr Opin Microbiol (2007) 1.80
Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals. Proc Natl Acad Sci U S A (2010) 1.72
The Salmonella kinase SteC targets the MAP kinase MEK to regulate the host actin cytoskeleton. Cell Host Microbe (2012) 1.66
Prefractionation by digitonin extraction increases representation of the cytosolic and intracellular proteome of Leishmania infantum. J Proteome Res (2006) 1.65
Members of a large retroposon family are determinants of post-transcriptional gene expression in Leishmania. PLoS Pathog (2007) 1.59
A common mechanism of stage-regulated gene expression in Leishmania mediated by a conserved 3'-untranslated region element. J Biol Chem (2002) 1.48
Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species. BMC Genomics (2008) 1.47
Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy. Genome Biol (2008) 1.38
Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Hum Mol Genet (2011) 1.32
Characterization and developmental gene regulation of a large gene family encoding amastin surface proteins in Leishmania spp. Mol Biochem Parasitol (2005) 1.30
SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy. Hum Mol Genet (2010) 1.30
Whole-genome comparative RNA expression profiling of axenic and intracellular amastigote forms of Leishmania infantum. Mol Biochem Parasitol (2009) 1.28
A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum. Proteomics (2006) 1.24
Distinct 3'-untranslated region elements regulate stage-specific mRNA accumulation and translation in Leishmania. J Biol Chem (2005) 1.24
Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathway. Sci Signal (2011) 1.24
Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes. Antimicrob Agents Chemother (2005) 1.24
Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species. Nucleic Acids Res (2011) 1.23
Coordinated gene expression by post-transcriptional regulons in African trypanosomes. J Biol (2009) 1.17
Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays. Nucleic Acids Res (2003) 1.16
Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry. Biochemistry (2002) 1.16
Novel membrane-bound eIF2alpha kinase in the flagellar pocket of Trypanosoma brucei. Eukaryot Cell (2007) 1.16
Trypanosome prereplication machinery contains a single functional orc1/cdc6 protein, which is typical of archaea. Eukaryot Cell (2009) 1.14
Comparative analysis of the excretory-secretory proteome of the muscle larva of Trichinella pseudospiralis and Trichinella spiralis. Int J Parasitol (2006) 1.13
Post-translational modifications of Trypanosoma cruzi histone H4. Mol Biochem Parasitol (2006) 1.12
Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis. Infect Immun (2005) 1.11
Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania. Nucleic Acids Res (2005) 1.11
Organization of satellite DNA in the genome of Trypanosoma cruzi. Mol Biochem Parasitol (2003) 1.10
Comparative genomics: from genotype to disease phenotype in the leishmaniases. Int J Parasitol (2007) 1.09
Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites. Eukaryot Cell (2006) 1.09
Asparagine deamidation perturbs antigen presentation on class II major histocompatibility complex molecules. J Biol Chem (2005) 1.08
Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. J Clin Invest (2014) 1.08
Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi. Eukaryot Cell (2005) 1.06
Expression of trypomastigote trans-sialidase in metacyclic forms of Trypanosoma cruzi increases parasite escape from its parasitophorous vacuole. Cell Microbiol (2006) 1.06
Promastigote to amastigote differentiation of Leishmania is markedly delayed in the absence of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation. Cell Microbiol (2011) 1.06
Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei. J Biol Chem (2010) 1.05
Morphological events during the Trypanosoma cruzi cell cycle. Protist (2006) 1.05
In vivo phosphorylation site mapping and functional characterization of Arabidopsis phototropin 1. Mol Plant (2007) 1.04
Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo. PLoS Genet (2012) 1.04
Organization and evolution of two SIDER retroposon subfamilies and their impact on the Leishmania genome. BMC Genomics (2009) 1.04
Trypanosoma cruzi histone H1 is phosphorylated in a typical cyclin dependent kinase site accordingly to the cell cycle. Mol Biochem Parasitol (2005) 1.02
Co-ordinated expression of lymphoid and myeloid specific transcription factors during B-1b cell differentiation into mononuclear phagocytes in vitro. Immunology (2008) 0.99
A novel class of developmentally regulated noncoding RNAs in Leishmania. Eukaryot Cell (2006) 0.98
Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice. Clin Vaccine Immunol (2011) 0.98
A proteomic analysis of penicillin resistance in Streptococcus pneumoniae reveals a novel role for PstS, a subunit of the phosphate ABC transporter. Mol Microbiol (2005) 0.97
Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms. PLoS One (2011) 0.97
Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas' disease after drug treatment. Clin Diagn Lab Immunol (2003) 0.96
Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae family. PLoS One (2013) 0.95
Leishmania infantum enhances human immunodeficiency virus type-1 replication in primary human macrophages through a complex cytokine network. Clin Immunol (2004) 0.95
Partial structure of glutamic acid and alanine-rich protein, a major surface glycoprotein of the insect stages of Trypanosoma congolense. J Biol Chem (2002) 0.95
Chromosome localization changes in the Trypanosoma cruzi nucleus. Eukaryot Cell (2002) 0.94
Role of transposable elements in trypanosomatids. Microbes Infect (2008) 0.93
Recombinant Leishmania tarentolae expressing the A2 virulence gene as a novel candidate vaccine against visceral leishmaniasis. Vaccine (2009) 0.93
In vitro and in vivo trypanocidal effects of the cyclopalladated compound 7a, a drug candidate for treatment of Chagas' disease. Antimicrob Agents Chemother (2010) 0.93
Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries. Org Biomol Chem (2011) 0.93
Comparative analysis of genomic sequences suggests that Trypanosoma cruzi CL Brener contains two sets of non-intercalated repeats of satellite DNA that correspond to T. cruzi I and T. cruzi II types. Mol Biochem Parasitol (2005) 0.92
Deadenylation-independent stage-specific mRNA degradation in Leishmania. Nucleic Acids Res (2008) 0.92
Recombinant Leishmania major secreting biologically active granulocyte-macrophage colony-stimulating factor survives poorly in macrophages in vitro and delays disease development in mice. Infect Immun (2003) 0.92
Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC. Anal Chem (2014) 0.92
Analysis of stage-specific expression of basic proteins in Leishmania infantum. J Proteome Res (2010) 0.91
Small-subunit rRNA processome proteins are translationally regulated during differentiation of Trypanosoma cruzi. Eukaryot Cell (2006) 0.90
Genetic diversity of Leishmania amazonensis strains isolated in northeastern Brazil as revealed by DNA sequencing, PCR-based analyses and molecular karyotyping. Kinetoplastid Biol Dis (2007) 0.90
Translational control through eIF2alpha phosphorylation during the Leishmania differentiation process. PLoS One (2012) 0.90
A survey of Leishmania braziliensis genome by shotgun sequencing. Mol Biochem Parasitol (2004) 0.90
T rypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas' disease. Cell Microbiol (2012) 0.90
Leishmania infantum promotes replication of HIV type 1 in human lymphoid tissue cultured ex vivo by inducing secretion of the proinflammatory cytokines TNF-alpha and IL-1 alpha. J Immunol (2004) 0.89
Development of novel prime-boost strategies based on a tri-gene fusion recombinant L. tarentolae vaccine against experimental murine visceral leishmaniasis. PLoS Negl Trop Dis (2013) 0.89
Rapid decay of unstable Leishmania mRNAs bearing a conserved retroposon signature 3'-UTR motif is initiated by a site-specific endonucleolytic cleavage without prior deadenylation. Nucleic Acids Res (2010) 0.89
The ribosomal RNA gene promoter and adjacent cis-acting DNA sequences govern plasmid DNA partitioning and stable inheritance in the parasitic protozoan Leishmania. Nucleic Acids Res (2004) 0.88
Amastin peptide-binding antibodies as biomarkers of active human visceral leishmaniasis. Clin Vaccine Immunol (2006) 0.88
Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection. PLoS One (2011) 0.87
Trialysin, a novel pore-forming protein from saliva of hematophagous insects activated by limited proteolysis. J Biol Chem (2001) 0.86
A proteomic approach to identify developmentally regulated proteins in Leishmania infantum. Proteomics (2002) 0.86
Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania. BMC Bioinformatics (2008) 0.85
The bacterium endosymbiont of Crithidia deanei undergoes coordinated division with the host cell nucleus. PLoS One (2010) 0.85
In primary human monocyte-derived macrophages exposed to Human immunodeficiency virus type 1, does the increased intracellular growth of Leishmania infantum rely on its enhanced uptake? J Gen Virol (2006) 0.85
RNA polymerase I-mediated transcription of a reporter gene integrated into different loci of Leishmania. Mol Biochem Parasitol (2002) 0.84
'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase. Bioorg Med Chem (2010) 0.84
DC-SIGN-mediated transfer of HIV-1 is compromised by the ability of Leishmania infantum to exploit DC-SIGN as a ligand. J Infect Dis (2005) 0.84
Subproteomic analysis of soluble proteins of the microsomal fraction from two Leishmania species. Comp Biochem Physiol Part D Genomics Proteomics (2006) 0.83
A protein of the leucine-rich repeats (LRRs) superfamily is implicated in antimony resistance in Leishmania infantum amastigotes. Mol Biochem Parasitol (2007) 0.83
Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells. Biochem J (2013) 0.83
Selective inactivation of SIDER2 retroposon-mediated mRNA decay contributes to stage- and species-specific gene expression in Leishmania. Mol Microbiol (2010) 0.83
Trypanosoma cruzi bromodomain factor 2 (BDF2) binds to acetylated histones and is accumulated after UV irradiation. Int J Parasitol (2008) 0.83
Active transcription and ultrastructural changes during Trypanosoma cruzi metacyclogenesis. An Acad Bras Cienc (2008) 0.82
Characterization of hibernating ribosomes in mammalian cells. Cell Cycle (2011) 0.82
Mycoleptones A-C and polyketides from the endophyte Mycoleptodiscus indicus. J Nat Prod (2014) 0.82
Lytic activity and structural differences of amphipathic peptides derived from trialysin. Biochemistry (2006) 0.82
Novel features of a PIWI-like protein homolog in the parasitic protozoan Leishmania. PLoS One (2012) 0.82
An Alba-domain protein contributes to the stage-regulated stability of amastin transcripts in Leishmania. Mol Microbiol (2013) 0.81
Label-free quantitative proteomic profiling identifies disruption of ubiquitin homeostasis as a key driver of Schwann cell defects in spinal muscular atrophy. J Proteome Res (2014) 0.81