Published in Biophys J on December 31, 2008
Separation of bacterial ribosomal ribonucleic acid from its macromolecular precursors by polyacrylamide gel electrophoresis. J Bacteriol (1968) 1.86
A study on the transcription of the polyoma viral genome. Proc Natl Acad Sci U S A (1970) 1.67
Cytoplasmic adenylylation and processing of maternal RNA. Proc Natl Acad Sci U S A (1973) 1.26
Transcription of spontaneously released bacterial deoxyribonucleic acid in frog auricles. J Bacteriol (1973) 0.75
Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. J Mol Biol (1962) 41.99
Determination of the base composition of deoxyribonucleic acid from its buoyant density in CsCl. J Mol Biol (1962) 36.74
The selective synthesis of informational RNA in bacteria. Proc Natl Acad Sci U S A (1961) 9.38
ABSENCE OF RIBOSOMAL RNA SYNTHESIS IN THE ANUCLEOLATE MUTANT OF XENOPUS LAEVIS. Proc Natl Acad Sci U S A (1964) 5.67
Purine and pyrimidine contents of some desoxypentose nucleic acids. J Gen Physiol (1950) 4.11
IDENTITY OF DNA AND DIVERSITY OF MESSENGER RNA MOLECULES IN NORMAL MOUSE TISSUES. Proc Natl Acad Sci U S A (1964) 3.18
A NEW METHOD FOR THE DETERMINATION OF THE BASE COMPOSITION OF RIBONUCLEIC ACID. J Biol Chem (1963) 2.84
Effects of actinomycin D on macromolecule synthesis and early development in sea urchin eggs. Biochem Biophys Res Commun (1963) 2.09
KINETICS OF INCORPORATION OF URIDINE-C14 INTO L CELL RNA. Biophys J (1964) 1.96
Activation of ribosomes in sea urchin eggs in response to fertilization. Exp Cell Res (1961) 1.91
The nucleic acids of the sea-urchin during embryonic development. J Biol Chem (1954) 1.80
The isolation of DNA-like RNA and ribosomal RNA from the nucleolo-chromosomal apparatus of mammalian cells. Biochim Biophys Acta (1962) 1.79
Activation of protein biosynthesis in non-nucleate fragments of sea urchin eggs. Biochem Biophys Res Commun (1964) 1.62
In vitro incorporation of amino acids into proteins stimulated by RNA from unfertilized sea urchin eggs. Biochem Biophys Res Commun (1964) 1.53
CHROMATOGRAPHIC SEPARATION OF ANNEALED AND ENZYMATICALLY SYNTHESIZED RNA-DNA HYBRIDS. Biophys J (1965) 1.50
Messenger RNA in early sea-urchin embryos: cytoplasmic particles. Science (1965) 1.49
OLD AND NEW RNA IN THE EMBRYOGENESIS OF THE PURPLE SEA URCHIN. Proc Natl Acad Sci U S A (1963) 1.46
Experimentally induced activation of the ribosomes of the unfertilized sea urchin egg. Proc Natl Acad Sci U S A (1965) 1.45
RIBONUCLEIC ACID METABOLISM FOLLOWING FERTILIZATION IN SEA URCHIN EGGS. Proc Natl Acad Sci U S A (1964) 1.35
BASE COMPOSITION OF RNA SYNTHESIZED DURING CLEAVAGE OF THE SEA URCHIN EMBRYO. Biochem Biophys Res Commun (1965) 1.15
PRELIMINARY STUDIES ON THE DEGRADATION AND SYSTHESIS OF RNA COMPONENTS DURING SEA URCHIN DEVELOPMENT. Exp Cell Res (1964) 0.96
METYLATION OF NUCLEIC ACIDS DURING SEA URCHIN EMBRYO DEVELOPMENT. J Mol Biol (1965) 0.95
Messenger RNA in early sea-urchin embryos: size classes. Science (1965) 0.94
Sedimentation characteristics of template RNA from rabbit reticulocytes and rat liver. Biochim Biophys Acta (1965) 0.83
Purification and some properties of sheep thyroid and rat liver messenger RNAs. Biochem Biophys Res Commun (1965) 0.80
FRACTIONS WITH DIFFERING BASE COMPOSITION IN RNA FROM MALIGNANT CELLS OF MOUSE. J Mol Biol (1963) 0.78
The caval sphincter in Phoca vitulina L. Nature (1954) 0.78
A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane. J Mol Biol (1965) 32.99
Electrophoretic separation of viral nucleic acids on polyacrylamide gels. J Mol Biol (1967) 13.29
Purification of the DNA polymerase of avian myeloblastosis virus. Biochim Biophys Acta (1971) 6.64
A molecular explanation of the bobbed mutants of Drosophila as partial deficiencies of "ribosomal" DNA. Genetics (1966) 5.94
Specific template requirments of RNA replicases. Proc Natl Acad Sci U S A (1965) 5.90
Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses. Nature (1970) 5.23
DNA-directed DNA polymerase activity in oncogenic RNA viruses. Nature (1970) 4.81
ENZYME FORMATION IN PROTOPLASTS OF BACILLUS MEGATERIUM. Proc Natl Acad Sci U S A (1955) 4.29
Mendelian Inheritance of Adaptive Enzymes. Proc Natl Acad Sci U S A (1944) 3.99
An extracellular Darwinian experiment with a self-duplicating nucleic acid molecule. Proc Natl Acad Sci U S A (1967) 3.99
Synthetic DNA-RNA hybrids and RNA-RNA duplexes as templates for the polymerases of the oncogenic RNA viruses. Nature (1970) 3.98
The synthesis of a self-propagating and infectious nucleic acid with a purified enzyme. Proc Natl Acad Sci U S A (1965) 3.71
Simultaneous detection of reverse transcriptase and high molecular weight RNA unique to oncogenic RNA viruses. Science (1971) 3.68
Sodium pyrophosphate inhibition of RNA.DNA hybrid degradation by reverse transcriptase. Proc Natl Acad Sci U S A (1978) 3.43
Genes and Nucleoproteins in the Synthesis of Enzymes. Science (1946) 3.18
Distinguishing reverse transcriptase of an RNA tumor virus from other known DNA polymerases. Proc Natl Acad Sci U S A (1971) 2.74
Recognition of size and sequence by an RNA replicase. Proc Natl Acad Sci U S A (1965) 2.59
RNA in human leukemic cells related to the RNA of a mouse leukemia virus (leukocytes-RNA-DNA hybridization-rauscher virus-polysomal RNA). Proc Natl Acad Sci U S A (1972) 2.55
Comparison of two serologically distinct ribonucleic acid bacteriophages. I. Properties of the viral particles. J Bacteriol (1966) 2.52
Human leukaemic cells contain reverse transcriptase associated with a high molecular weight virus-related RNA. Nat New Biol (1972) 2.40
Synthesis of full-length DNA copies of avian myeloblastosis virus RNA in high yields. Proc Natl Acad Sci U S A (1977) 2.37
On the chromosomal distribution of DNA complementary to ribosomal and soluble RNA. Natl Cancer Inst Monogr (1966) 2.32
Presence in human breast cancer of RNA homologous to mouse mammary tumour virus RNA. Nature (1972) 2.31
In vitro synthesis of an infectious mutant RNA with a normal RNA replicase. Science (1966) 2.30
SEPARATION OF THE RNA MESSAGE TRANSCRIBED IN RESPONSE TO A SPECIFIC INDUCER. Proc Natl Acad Sci U S A (1963) 2.28
The synthesis of infectious RNA with a replicase purified according to its size and density. Proc Natl Acad Sci U S A (1966) 2.27
On the redundancy of DNA complementary to amino acid tranfer RNA and its absence from the nucleolar organizer region of Drosophila melanogaster. Genetics (1966) 2.21
Autocatalytic synthesis of a viral RNA in vitro. Science (1965) 2.10
The in vitro synthesis of a noninfectious complex containing biologically active viral RNA. Proc Natl Acad Sci U S A (1966) 2.10
Conditions for the selective synthesis of DNA complementary to template RNA. Biochim Biophys Acta (1973) 2.08
Decreased globin messenger RNA in thalassemia detected by molecular hybridization. Proc Natl Acad Sci U S A (1973) 2.07
Particles containing RNA-instructed DNA polymerase and virus-related RNA in human breast cancers. Proc Natl Acad Sci U S A (1972) 2.02
Human sarcomas contain RNA related to the RNA of a mouse leukemia virus. Science (1972) 1.98
Viral-related RNA in Hodgkins' disease and other human lymphomas. Proc Natl Acad Sci U S A (1972) 1.98
Further extracellular Darwinian experiments with replicating RNA molecules: diverse variants isolated under different selective conditions. Proc Natl Acad Sci U S A (1969) 1.89
Purification and detection of reverse transcriptase in viruses and cells. Methods Enzymol (1974) 1.89
The mechanism of RNA replication. Cold Spring Harb Symp Quant Biol (1968) 1.80
Complete nucleotide sequence of a replicating RNA molecule. Science (1973) 1.78
Evidence for translation of viral-specific RNA in cells of a mouse mammary carcinoma. Proc Natl Acad Sci U S A (1972) 1.76
Serological analysis of the deoxyribonucleic acid polymerase of avian oncornaviruses. II. Comparison of avian deoxyribonucleic acid polymerases. J Virol (1972) 1.75
Detection of RNA-instructed DNA polymerase and high molecular weight RNA in malignant tissue. Proc Natl Acad Sci U S A (1972) 1.73
Use of micrococcal nuclease to monitor hybridization reactions with DNA. Anal Biochem (1974) 1.71
An analysis by gel electrophoresis of Q-beta-RNA complexes formed during the latent period of an in vitro synthesis. Proc Natl Acad Sci U S A (1967) 1.67
DNA polymerase activities in varions of visna virus, a causative agent of a "slow" neurological disease. Proc Natl Acad Sci U S A (1971) 1.67
RNA-dependent DNA polymerase activity in virus-like particles isolated from human milk. Nature (1971) 1.63
The kinetics of product appearance and template involvement in the in vitro replication of viral RNA. Proc Natl Acad Sci U S A (1967) 1.59
DNA polymerase activities and nucleic acid components of virions isolated from a spontaneous mammary carcinoma from a rhesus monkey. Proc Natl Acad Sci U S A (1971) 1.57
A replicating RNA molecule suitable for a detailed analysis of extracellular evolution and replication. Proc Natl Acad Sci U S A (1972) 1.55
An estimation of genetic messages in the unfertilized echinoid egg. Proc Natl Acad Sci U S A (1966) 1.52
Detection in human breast carcinomas of an antigen immunologically related to a group-specific antigen of mouse mammary tumor virus. Proc Natl Acad Sci U S A (1978) 1.51
Evolution in vitro: sequence and phenotype of a mutant RNA resistant to ethidium bromide. J Mol Biol (1974) 1.51
Properties of retrovirus-like particles produced by a human breast carcinoma cell line: immunological relationship with mouse mammary tumor virus proteins. Proc Natl Acad Sci U S A (1984) 1.50
Absence of polymerase protein in virions of alpha-type rous sarcoma virus. Science (1972) 1.46
Burkitt's tumors contain particles encapsulating RNA-instructed DNA polymerase and high molecular weight virus-related RNA. Proc Natl Acad Sci U S A (1973) 1.44
Comparison of two serologically distinct ribonucleic acid bacteriophages. II. Properties of the nucleic acids and coat proteins. J Bacteriol (1966) 1.44
A search for an intermediate involving a complement during synchronous synthesis by a purified RNA replicase. Proc Natl Acad Sci U S A (1966) 1.43
Determination of natural host taxonomy of RNA tumor viruses by molecular hybridization: application to RD-114, a candidate human virus. Proc Natl Acad Sci U S A (1973) 1.40
The purification of a gs antigen of the murine mammary tumor virus and its quantitation by radioimmunoassay. Virology (1976) 1.39
The sequence at the 5' terminus of a self-replicating variant of viral Q-beta ribonucleic acid. Biochemistry (1968) 1.39
RNA primer used in synthesis of anticomplementary DNA by reverse transcriptase of avian myeloblastosis virus. Proc Natl Acad Sci U S A (1980) 1.37
The dissociation of Q-beta-replicase and the relation of one of the components to a poly-C-dependent poly-G-polymerase. Proc Natl Acad Sci U S A (1967) 1.37
Virus-related RNA in human and mouse mammary tumors. J Natl Cancer Inst (1972) 1.34
Plasma levels of a viral protein as a diagnostic signal for the presence of tumor : the murine mammary tumor model. Proc Natl Acad Sci U S A (1976) 1.33
Nuclear DNA sequences present in human leukemic cells and absent in normal leukocytes. Proc Natl Acad Sci U S A (1972) 1.32
Deoxyribonucleic acid polymerase of Rous sarcoma virus: reaction conditions and analysis of the reaction product nucleic acids. J Virol (1971) 1.29
Detection of high-molecular-weight RNA in particles from human milk. Science (1972) 1.27
Human breast carcinoma antigen is immunologically related to the polypeptide of the group-specific glycoprotein of mouse mammary tumor virus. Proc Natl Acad Sci U S A (1979) 1.26
RNA related to that of a murine leukemia virus in Burkitt's tumors and nasopharyngeal carcinomas. Proc Natl Acad Sci U S A (1973) 1.23
The in vitro translation of a monocistronic message. Proc Natl Acad Sci U S A (1965) 1.22
The cloning of a self-replicating RNA molecule. Proc Natl Acad Sci U S A (1968) 1.22
Quantitation of RNA tumor viruses and viruslike particles in human milk by hybridization to polyadenylic acid sequences. Science (1973) 1.21
In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide. J Mol Biol (1970) 1.19
A comparative study of the biologic and molecular basis of murine mammary carcinoma: a model for human breast cancer. J Natl Cancer Inst (1973) 1.19
The presence of unique DNA sequences after viral induction of leukemia in mice. (RNA tumor virus-nucleic acid hybridization-insertion of viral DNA). Proc Natl Acad Sci U S A (1974) 1.19
Evidence for RNA tumor viruses in human lymphomas including Burkitt's disease. Cancer Res (1973) 1.19
Studies in the replication of viral RNA. J Cell Physiol (1967) 1.14
Direct participation of a host protein in the replication of viral RNA in vitro. Proc Natl Acad Sci U S A (1968) 1.11
Exhaustive hybridization and its application to an analysis of the ribonucleic acid synthesized in T4-infected cells. Biochemistry (1968) 1.11
Reverse transcriptase and high molecular weight RNA in particles from mouse and human milk. J Natl Cancer Inst (1972) 1.10
The mechanism of replication: a novel polarity reversal in the in vitro synthesis of Q-beta-RNA and its complement. Proc Natl Acad Sci U S A (1967) 1.10
Synthesis of DNA complements of natural RNAs: a general approach. Proc Natl Acad Sci U S A (1971) 1.09
Plasma levels of a viral protein as a diagnostic signal for the presence of mammary tumor: the effect of tumor removal. J Exp Med (1977) 1.09
Detection of viral proteins in mouse mammary tumors by immunoperoxidase staining of paraffin sections. Proc Natl Acad Sci U S A (1978) 1.09
Leukemia-specific DNA sequences in leukocytes of the leukemic member of identical twins. Proc Natl Acad Sci U S A (1973) 1.08
A simple purification of avian myeloblastosis virus reverse transcriptase for full-length transcription of 35 S RNA. Anal Biochem (1980) 1.08
High-dose 5-fluorouracil with delayed uridine "rescue" in mice. Cancer Res (1982) 1.06
The mechanism of Q replication: sequence at the 5' terminus of a 6-S RNA template. Biochim Biophys Acta (1971) 1.05
Examination of the Qbeta-replicase reaction by sucrose gradient and gel electrophoresis. J Virol (1967) 1.05
Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation. Proc Natl Acad Sci U S A (1980) 1.05
Particles with RNA of high molecular weight and RNA-directed DNA polymerase in human brain tumors. Proc Natl Acad Sci U S A (1973) 1.03
Biochemical characterization of putative subviral particulates from human malignant breast tumors. Cancer Res (1975) 1.02
Characterisation of a virus (HL23V) isolated from cultured acute myelogenous leukaemic cells. Nature (1976) 1.01
Specific cleavage of Qbeta-RNA and identification of the fragment carrying the 3'-OH terminus. Proc Natl Acad Sci U S A (1967) 1.01
Potentiation of the anti-tumor activity of 5FU by thymidine and its correlation with the formation of (5FU)RNA. Cancer (1980) 1.01
Purification of RNA-instructed DNA polymerase from human leukemic spleens. Proc Natl Acad Sci U S A (1975) 1.01
Sequence homology between the RNA of Mason-Pfizer monkey virus and the RNA of human malignant breast tumors. Proc Natl Acad Sci U S A (1974) 0.99
Serological analysis of reverse transcriptase of the Mason-Pfizer monkey virus. Virology (1974) 0.96
Purification and characterization of the DNA polymerase of human breast cancer particles. Proc Natl Acad Sci U S A (1977) 0.95
RNA replication: required intermediates and the dissociation of template, product, and Q beta replicase. Biochemistry (1979) 0.95