Published in Proc Natl Acad Sci U S A on August 01, 1965
Structure-independent nucleotide sequence analysis. Proc Natl Acad Sci U S A (1979) 8.65
Characteristics and purification of PRR1, an RNA phage specific for the broad host range Pseudomonas R1822 drug resistance plasmid. J Virol (1973) 4.51
An extracellular Darwinian experiment with a self-duplicating nucleic acid molecule. Proc Natl Acad Sci U S A (1967) 3.99
The synthesis of a self-propagating and infectious nucleic acid with a purified enzyme. Proc Natl Acad Sci U S A (1965) 3.71
Translation of the genetic message: factors involved in the initiation of protein synthesis. Proc Natl Acad Sci U S A (1966) 3.54
Isolation and mapping of polynucleotide phosphorylase mutants of Escherichia coli. J Bacteriol (1969) 3.03
RNA sequencing with radioactive chain-terminating ribonucleotides. Proc Natl Acad Sci U S A (1978) 2.67
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus. J Virol (2000) 2.65
Recognition of size and sequence by an RNA replicase. Proc Natl Acad Sci U S A (1965) 2.59
Comparison of two serologically distinct ribonucleic acid bacteriophages. I. Properties of the viral particles. J Bacteriol (1966) 2.52
Messenger selection by bacterial ribosomes. Proc Natl Acad Sci U S A (1973) 2.09
Further extracellular Darwinian experiments with replicating RNA molecules: diverse variants isolated under different selective conditions. Proc Natl Acad Sci U S A (1969) 1.89
Advances in nucleic acid-based detection methods. Clin Microbiol Rev (1992) 1.84
An analysis by gel electrophoresis of Q-beta-RNA complexes formed during the latent period of an in vitro synthesis. Proc Natl Acad Sci U S A (1967) 1.67
Grouping of RNA phages based on the template specificity of their RNA replicases. Proc Natl Acad Sci U S A (1971) 1.62
Replication of viral RNA. XI. Synthesis of viral "minus" strands in vitro. Proc Natl Acad Sci U S A (1966) 1.60
The kinetics of product appearance and template involvement in the in vitro replication of viral RNA. Proc Natl Acad Sci U S A (1967) 1.59
A replicating RNA molecule suitable for a detailed analysis of extracellular evolution and replication. Proc Natl Acad Sci U S A (1972) 1.55
Replication of viral RNA. 13. The early product of phage RNA synthesis in vitro. Proc Natl Acad Sci U S A (1967) 1.49
Comparison of two serologically distinct ribonucleic acid bacteriophages. II. Properties of the nucleic acids and coat proteins. J Bacteriol (1966) 1.44
A search for an intermediate involving a complement during synchronous synthesis by a purified RNA replicase. Proc Natl Acad Sci U S A (1966) 1.43
Translation of the genome of a ribonucleic acid bacteriophage. Bacteriol Rev (1972) 1.40
Replication of plant RNA virus genomes in a cell-free extract of evacuolated plant protoplasts. Proc Natl Acad Sci U S A (2004) 1.39
Symposium on replication of viral nucleic acids. 3. Replication of mengovirus ribonucleic acid. Bacteriol Rev (1966) 1.39
The dissociation of Q-beta-replicase and the relation of one of the components to a poly-C-dependent poly-G-polymerase. Proc Natl Acad Sci U S A (1967) 1.37
Symposium on replication of viral nucleic acids. I. Formation and properties of a replicative intermediate in the biosynthesis of viral ribonucleic acid. Bacteriol Rev (1966) 1.36
Secondary structure formation during RNA synthesis. Nucleic Acids Res (1981) 1.33
The nucleotide sequence at the 5'-terminus of the Q RNA minus trand. Proc Natl Acad Sci U S A (1970) 1.28
Replication of viral RNA. XIV. Single-stranded minus strands as template for the synthesis of viral plus strands in vitro. Proc Natl Acad Sci U S A (1967) 1.26
The cloning of a self-replicating RNA molecule. Proc Natl Acad Sci U S A (1968) 1.22
Ribonucleic acid synthesis by Escherichia coli C 3000/L after infection by the ribonucleic acid coliphage ZIK/1, and properties of the coliphage-induced double-stranged ribonucleic acid. Biochem J (1966) 1.17
Replication of viral RNA, XVI. Enzymatic synthesis of infectious virual RNA with noninfectious Q-beta minus strands as template. Proc Natl Acad Sci U S A (1968) 1.17
Functions of the two particles of tobacco rattle virus. J Virol (1969) 1.15
Synthesis of complementary strands of heterologous RNAs with Qbeta replicase. Proc Natl Acad Sci U S A (1974) 1.13
Q beta replicase template specificity: different templates require different GTP concentrations for initiation. Proc Natl Acad Sci U S A (1980) 1.12
Direct participation of a host protein in the replication of viral RNA in vitro. Proc Natl Acad Sci U S A (1968) 1.11
Replication of RNA viruses. V. Template activity of synthetic ribopolymers in the Q-beta RNA polymerase reaction. Proc Natl Acad Sci U S A (1967) 1.11
Isolation and subunit structure of polycytidylate-dependent RNA polymerase of encephalomyocarditis virus. Proc Natl Acad Sci U S A (1972) 1.11
The mechanism of replication: a novel polarity reversal in the in vitro synthesis of Q-beta-RNA and its complement. Proc Natl Acad Sci U S A (1967) 1.10
Synthesis of DNA complements of natural RNAs: a general approach. Proc Natl Acad Sci U S A (1971) 1.09
Characterization of the initial peptide of Q-beta RNA polymerase and control of its synthesis. Proc Natl Acad Sci U S A (1971) 1.08
Replication of RNA viruses, IV. Initiation of RNA synthesis by the q-beta RNA polymerase. Proc Natl Acad Sci U S A (1967) 1.08
Chain extension of ribonucleic acid by enzymes from rat liver cytoplasm. Biochem J (1968) 1.06
Examination of the Qbeta-replicase reaction by sucrose gradient and gel electrophoresis. J Virol (1967) 1.05
Evidence for de novo production of self-replicating and environmentally adapted RNA structures by bacteriophage Qbeta replicase. Proc Natl Acad Sci U S A (1975) 1.01
Specific cleavage of Qbeta-RNA and identification of the fragment carrying the 3'-OH terminus. Proc Natl Acad Sci U S A (1967) 1.01
Effect of bacteriophage R17 infection on host-directed synthesis of ribosomal ribonucleates. J Virol (1967) 1.01
On the chemical nature of transfer factor. Proc Natl Acad Sci U S A (1974) 0.98
Physical properties of single- and double-stranded coliphage ribonucleic acid. Biochem J (1966) 0.95
Selective interference with viral RNA formation in vitro by specific inhibition with synthetic polyribonucleotides. Proc Natl Acad Sci U S A (1966) 0.95
Q-beta-replicase and E. coli transcriptase: requirements for substrate selection as revealed by a study of base analogs. Proc Natl Acad Sci U S A (1970) 0.94
A rationale for an analysis of RNA replication. Proc Natl Acad Sci U S A (1966) 0.90
Amplifiable messenger RNA. Proc Natl Acad Sci U S A (1992) 0.88
Nucleotide sequence of microvariant RNA: another small replicating molecule. Proc Natl Acad Sci U S A (1975) 0.87
Symposium on replication of viral nucleic acids. II. Ribonucleic acid virus replication. Bacteriol Rev (1966) 0.85
The immediate precursor of viral RNA in the Q-beta-repicase reaction. Proc Natl Acad Sci U S A (1968) 0.84
Minimal requirements for template recognition by bacteriophage Qbeta replicase: approach to general RNA-dependent RNA synthesis. Proc Natl Acad Sci U S A (1975) 0.83
DNA aptamers against the Lup an 1 food allergen. PLoS One (2012) 0.82
The mechanism and direction of RNA synthesis templated by free minus strands of a "little" variant of Q-beta RNA. Proc Natl Acad Sci U S A (1968) 0.80
Isolation and properties of RNA replicases induced by SP and FI phages. Proc Natl Acad Sci U S A (1971) 0.79
Comparison of pausing during transcription and replication. Nucleic Acids Res (1985) 0.77
Structures and functions of Qβ replicase: translation factors beyond protein synthesis. Int J Mol Sci (2014) 0.77
Synthesis of chloroplast DNA in isolated chloroplasts. J Cell Biol (1968) 0.75
Problems of an RNA Genome Operating in a DNA-Dominated Biological Universe. J Gen Physiol (1966) 0.75
Identification of guanosine triphosphate as the 5'-terminus of RNA from bacteriophage Q-beta and R23. Proc Natl Acad Sci U S A (1968) 0.75
AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES. Proc Natl Acad Sci U S A (1963) 5.61
REPLICATION OF VIRAL RNA, III. DOUBLE-STRANDED REPLICATIVE FORM OF MSW PHAGE RNA. Proc Natl Acad Sci U S A (1964) 4.24
Preliminary data on a virus-specific enzyme system responsible for the synthesis of viral RNA. Biochem Biophys Res Commun (1962) 3.00
Induction by an RNA phage of an enzyme catalyzing incorporation of ribonucleotides into ribonucleic acid. Proc Natl Acad Sci U S A (1963) 2.99
Ribonucleic acid-dependent ribonucleotide incorporation. I. Purification and properties of the enzyme. J Biol Chem (1962) 2.62
Ribonucleic acid polymerase of Azotobacter vinelandii. I. Priming by polyribonucleotides. Proc Natl Acad Sci U S A (1963) 2.61
Conservation of a viral RNA genome during replication and translation. Proc Natl Acad Sci U S A (1963) 2.61
The biosynthesis of RNA: printing by polyribonucleotides. Proc Natl Acad Sci U S A (1962) 2.24
REPLICATION OF RNA VIRUSES I. CHARACTERIZATION OF A VIRAL RNA-DEPENDENT RNA POLYMERASE. J Mol Biol (1965) 1.83
THE SATELLITE TOBACCO NECROSIS VIRUS: A SINGLE PROTEIN AND ITS GENETIC CODE. Proc Natl Acad Sci U S A (1964) 1.59
REPLICATION OF RNA VIRUSES. II. THE RNA PRODUCT OF A REACTION CATALYZED BY A VIRAL RNA-DEPENDENT RNA POLYMERASE. J Mol Biol (1965) 1.42
The preparation of labeled uridine 5-triphosphate by the action of mono- and diphosphouridine kinases from Escherichia coli. Biochim Biophys Acta (1962) 1.35
A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane. J Mol Biol (1965) 32.99
Electrophoretic separation of viral nucleic acids on polyacrylamide gels. J Mol Biol (1967) 13.29
Purification of the DNA polymerase of avian myeloblastosis virus. Biochim Biophys Acta (1971) 6.64
A molecular explanation of the bobbed mutants of Drosophila as partial deficiencies of "ribosomal" DNA. Genetics (1966) 5.94
Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses. Nature (1970) 5.23
DNA-directed DNA polymerase activity in oncogenic RNA viruses. Nature (1970) 4.81
ENZYME FORMATION IN PROTOPLASTS OF BACILLUS MEGATERIUM. Proc Natl Acad Sci U S A (1955) 4.29
Mendelian Inheritance of Adaptive Enzymes. Proc Natl Acad Sci U S A (1944) 3.99
An extracellular Darwinian experiment with a self-duplicating nucleic acid molecule. Proc Natl Acad Sci U S A (1967) 3.99
Synthetic DNA-RNA hybrids and RNA-RNA duplexes as templates for the polymerases of the oncogenic RNA viruses. Nature (1970) 3.98
The synthesis of a self-propagating and infectious nucleic acid with a purified enzyme. Proc Natl Acad Sci U S A (1965) 3.71
Simultaneous detection of reverse transcriptase and high molecular weight RNA unique to oncogenic RNA viruses. Science (1971) 3.68
Sodium pyrophosphate inhibition of RNA.DNA hybrid degradation by reverse transcriptase. Proc Natl Acad Sci U S A (1978) 3.43
Genes and Nucleoproteins in the Synthesis of Enzymes. Science (1946) 3.18
Distinguishing reverse transcriptase of an RNA tumor virus from other known DNA polymerases. Proc Natl Acad Sci U S A (1971) 2.74
Recognition of size and sequence by an RNA replicase. Proc Natl Acad Sci U S A (1965) 2.59
RNA in human leukemic cells related to the RNA of a mouse leukemia virus (leukocytes-RNA-DNA hybridization-rauscher virus-polysomal RNA). Proc Natl Acad Sci U S A (1972) 2.55
Comparison of two serologically distinct ribonucleic acid bacteriophages. I. Properties of the viral particles. J Bacteriol (1966) 2.52
Human leukaemic cells contain reverse transcriptase associated with a high molecular weight virus-related RNA. Nat New Biol (1972) 2.40
Synthesis of full-length DNA copies of avian myeloblastosis virus RNA in high yields. Proc Natl Acad Sci U S A (1977) 2.37
On the chromosomal distribution of DNA complementary to ribosomal and soluble RNA. Natl Cancer Inst Monogr (1966) 2.32
Presence in human breast cancer of RNA homologous to mouse mammary tumour virus RNA. Nature (1972) 2.31
In vitro synthesis of an infectious mutant RNA with a normal RNA replicase. Science (1966) 2.30
SEPARATION OF THE RNA MESSAGE TRANSCRIBED IN RESPONSE TO A SPECIFIC INDUCER. Proc Natl Acad Sci U S A (1963) 2.28
The synthesis of infectious RNA with a replicase purified according to its size and density. Proc Natl Acad Sci U S A (1966) 2.27
On the redundancy of DNA complementary to amino acid tranfer RNA and its absence from the nucleolar organizer region of Drosophila melanogaster. Genetics (1966) 2.21
Autocatalytic synthesis of a viral RNA in vitro. Science (1965) 2.10
The in vitro synthesis of a noninfectious complex containing biologically active viral RNA. Proc Natl Acad Sci U S A (1966) 2.10
Conditions for the selective synthesis of DNA complementary to template RNA. Biochim Biophys Acta (1973) 2.08
Decreased globin messenger RNA in thalassemia detected by molecular hybridization. Proc Natl Acad Sci U S A (1973) 2.07
Particles containing RNA-instructed DNA polymerase and virus-related RNA in human breast cancers. Proc Natl Acad Sci U S A (1972) 2.02
Human sarcomas contain RNA related to the RNA of a mouse leukemia virus. Science (1972) 1.98
Viral-related RNA in Hodgkins' disease and other human lymphomas. Proc Natl Acad Sci U S A (1972) 1.98
Further extracellular Darwinian experiments with replicating RNA molecules: diverse variants isolated under different selective conditions. Proc Natl Acad Sci U S A (1969) 1.89
Purification and detection of reverse transcriptase in viruses and cells. Methods Enzymol (1974) 1.89
The mechanism of RNA replication. Cold Spring Harb Symp Quant Biol (1968) 1.80
Complete nucleotide sequence of a replicating RNA molecule. Science (1973) 1.78
Evidence for translation of viral-specific RNA in cells of a mouse mammary carcinoma. Proc Natl Acad Sci U S A (1972) 1.76
Serological analysis of the deoxyribonucleic acid polymerase of avian oncornaviruses. II. Comparison of avian deoxyribonucleic acid polymerases. J Virol (1972) 1.75
Detection of RNA-instructed DNA polymerase and high molecular weight RNA in malignant tissue. Proc Natl Acad Sci U S A (1972) 1.73
Use of micrococcal nuclease to monitor hybridization reactions with DNA. Anal Biochem (1974) 1.71
DNA polymerase activities in varions of visna virus, a causative agent of a "slow" neurological disease. Proc Natl Acad Sci U S A (1971) 1.67
An analysis by gel electrophoresis of Q-beta-RNA complexes formed during the latent period of an in vitro synthesis. Proc Natl Acad Sci U S A (1967) 1.67
RNA-dependent DNA polymerase activity in virus-like particles isolated from human milk. Nature (1971) 1.63
Grouping of RNA phages based on the template specificity of their RNA replicases. Proc Natl Acad Sci U S A (1971) 1.62
The kinetics of product appearance and template involvement in the in vitro replication of viral RNA. Proc Natl Acad Sci U S A (1967) 1.59
DNA polymerase activities and nucleic acid components of virions isolated from a spontaneous mammary carcinoma from a rhesus monkey. Proc Natl Acad Sci U S A (1971) 1.57
A replicating RNA molecule suitable for a detailed analysis of extracellular evolution and replication. Proc Natl Acad Sci U S A (1972) 1.55
An estimation of genetic messages in the unfertilized echinoid egg. Proc Natl Acad Sci U S A (1966) 1.52
Detection in human breast carcinomas of an antigen immunologically related to a group-specific antigen of mouse mammary tumor virus. Proc Natl Acad Sci U S A (1978) 1.51
Evolution in vitro: sequence and phenotype of a mutant RNA resistant to ethidium bromide. J Mol Biol (1974) 1.51
Properties of retrovirus-like particles produced by a human breast carcinoma cell line: immunological relationship with mouse mammary tumor virus proteins. Proc Natl Acad Sci U S A (1984) 1.50
Absence of polymerase protein in virions of alpha-type rous sarcoma virus. Science (1972) 1.46
Burkitt's tumors contain particles encapsulating RNA-instructed DNA polymerase and high molecular weight virus-related RNA. Proc Natl Acad Sci U S A (1973) 1.44
Comparison of two serologically distinct ribonucleic acid bacteriophages. II. Properties of the nucleic acids and coat proteins. J Bacteriol (1966) 1.44
A search for an intermediate involving a complement during synchronous synthesis by a purified RNA replicase. Proc Natl Acad Sci U S A (1966) 1.43
Determination of natural host taxonomy of RNA tumor viruses by molecular hybridization: application to RD-114, a candidate human virus. Proc Natl Acad Sci U S A (1973) 1.40
The purification of a gs antigen of the murine mammary tumor virus and its quantitation by radioimmunoassay. Virology (1976) 1.39
The sequence at the 5' terminus of a self-replicating variant of viral Q-beta ribonucleic acid. Biochemistry (1968) 1.39
RNA primer used in synthesis of anticomplementary DNA by reverse transcriptase of avian myeloblastosis virus. Proc Natl Acad Sci U S A (1980) 1.37
The dissociation of Q-beta-replicase and the relation of one of the components to a poly-C-dependent poly-G-polymerase. Proc Natl Acad Sci U S A (1967) 1.37
Virus-related RNA in human and mouse mammary tumors. J Natl Cancer Inst (1972) 1.34
Plasma levels of a viral protein as a diagnostic signal for the presence of tumor : the murine mammary tumor model. Proc Natl Acad Sci U S A (1976) 1.33
Nuclear DNA sequences present in human leukemic cells and absent in normal leukocytes. Proc Natl Acad Sci U S A (1972) 1.32
Deoxyribonucleic acid polymerase of Rous sarcoma virus: reaction conditions and analysis of the reaction product nucleic acids. J Virol (1971) 1.29
Detection of high-molecular-weight RNA in particles from human milk. Science (1972) 1.27
Human breast carcinoma antigen is immunologically related to the polypeptide of the group-specific glycoprotein of mouse mammary tumor virus. Proc Natl Acad Sci U S A (1979) 1.26
RNA related to that of a murine leukemia virus in Burkitt's tumors and nasopharyngeal carcinomas. Proc Natl Acad Sci U S A (1973) 1.23
The in vitro translation of a monocistronic message. Proc Natl Acad Sci U S A (1965) 1.22
The cloning of a self-replicating RNA molecule. Proc Natl Acad Sci U S A (1968) 1.22
Quantitation of RNA tumor viruses and viruslike particles in human milk by hybridization to polyadenylic acid sequences. Science (1973) 1.21
In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide. J Mol Biol (1970) 1.19
A comparative study of the biologic and molecular basis of murine mammary carcinoma: a model for human breast cancer. J Natl Cancer Inst (1973) 1.19
The presence of unique DNA sequences after viral induction of leukemia in mice. (RNA tumor virus-nucleic acid hybridization-insertion of viral DNA). Proc Natl Acad Sci U S A (1974) 1.19
Evidence for RNA tumor viruses in human lymphomas including Burkitt's disease. Cancer Res (1973) 1.19
Studies in the replication of viral RNA. J Cell Physiol (1967) 1.14
Direct participation of a host protein in the replication of viral RNA in vitro. Proc Natl Acad Sci U S A (1968) 1.11
Exhaustive hybridization and its application to an analysis of the ribonucleic acid synthesized in T4-infected cells. Biochemistry (1968) 1.11
Reverse transcriptase and high molecular weight RNA in particles from mouse and human milk. J Natl Cancer Inst (1972) 1.10
The mechanism of replication: a novel polarity reversal in the in vitro synthesis of Q-beta-RNA and its complement. Proc Natl Acad Sci U S A (1967) 1.10
Synthesis of DNA complements of natural RNAs: a general approach. Proc Natl Acad Sci U S A (1971) 1.09
Plasma levels of a viral protein as a diagnostic signal for the presence of mammary tumor: the effect of tumor removal. J Exp Med (1977) 1.09
Detection of viral proteins in mouse mammary tumors by immunoperoxidase staining of paraffin sections. Proc Natl Acad Sci U S A (1978) 1.09
Leukemia-specific DNA sequences in leukocytes of the leukemic member of identical twins. Proc Natl Acad Sci U S A (1973) 1.08
A simple purification of avian myeloblastosis virus reverse transcriptase for full-length transcription of 35 S RNA. Anal Biochem (1980) 1.08
High-dose 5-fluorouracil with delayed uridine "rescue" in mice. Cancer Res (1982) 1.06
The mechanism of Q replication: sequence at the 5' terminus of a 6-S RNA template. Biochim Biophys Acta (1971) 1.05
A chemical and physical characterization of echinoid RNA during early embryogenesis. Biophys J (2008) 1.05
Examination of the Qbeta-replicase reaction by sucrose gradient and gel electrophoresis. J Virol (1967) 1.05
Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation. Proc Natl Acad Sci U S A (1980) 1.05
Poly(U) polymerase in rat brain. Nature (1975) 1.04
Particles with RNA of high molecular weight and RNA-directed DNA polymerase in human brain tumors. Proc Natl Acad Sci U S A (1973) 1.03
Biochemical characterization of putative subviral particulates from human malignant breast tumors. Cancer Res (1975) 1.02
Characterisation of a virus (HL23V) isolated from cultured acute myelogenous leukaemic cells. Nature (1976) 1.01