Published in Eur J Immunol on March 01, 2009
Understanding latent tuberculosis: a moving target. J Immunol (2010) 2.95
Vaccines against tuberculosis: where are we and where do we need to go? PLoS Pathog (2012) 2.87
Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns. Am J Respir Crit Care Med (2010) 2.64
Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells. Eur J Immunol (2010) 2.25
Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load. J Immunol (2011) 2.07
Tuberculin-specific T cells are reduced in active pulmonary tuberculosis compared to LTBI or status post BCG vaccination. J Infect Dis (2010) 1.58
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset. PLoS Pathog (2013) 1.54
Early dynamics of T helper cell cytokines and T regulatory cells in response to treatment of active Mycobacterium tuberculosis infection. Clin Exp Immunol (2015) 1.46
Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis. PLoS One (2010) 1.45
Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment. PLoS One (2010) 1.44
Latent tuberculosis: what the host "sees"? Immunol Res (2011) 1.35
Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis. Front Immunol (2014) 1.28
Whole-blood flow-cytometric analysis of antigen-specific CD4 T-cell cytokine profiles distinguishes active tuberculosis from non-active states. PLoS One (2011) 1.24
T cells in mycobacterial infection and disease. Curr Opin Immunol (2009) 1.22
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. PLoS Pathog (2015) 1.21
Distinct effector memory CD4+ T cell signatures in latent Mycobacterium tuberculosis infection, BCG vaccination and clinically resolved tuberculosis. PLoS One (2012) 1.19
Complex cytokine profiles induced by BCG vaccination in UK infants. Vaccine (2009) 1.09
Production of TNF-alpha, IL-12(p40) and IL-17 can discriminate between active TB disease and latent infection in a West African cohort. PLoS One (2010) 1.09
Systemic BCG immunization induces persistent lung mucosal multifunctional CD4 T(EM) cells which expand following virulent mycobacterial challenge. PLoS One (2011) 1.08
Simian immunodeficiency virus-induced changes in T cell cytokine responses in cynomolgus macaques with latent Mycobacterium tuberculosis infection are associated with timing of reactivation. J Immunol (2011) 1.06
Cutting edge: Direct recognition of infected cells by CD4 T cells is required for control of intracellular Mycobacterium tuberculosis in vivo. J Immunol (2013) 1.02
Immunodiagnosis of tuberculosis: a dynamic view of biomarker discovery. Clin Microbiol Rev (2011) 1.01
Identification of probable early-onset biomarkers for tuberculosis disease progression. PLoS One (2011) 1.00
Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines. PLoS Pathog (2010) 0.99
HIV-1 and the immune response to TB. Future Virol (2013) 0.97
HIV-1 infection alters CD4+ memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis. Eur J Immunol (2012) 0.97
Identification of immunological biomarkers which may differentiate latent tuberculosis from exposure to environmental nontuberculous mycobacteria in children. Clin Vaccine Immunol (2013) 0.96
T cell susceptibility to HIV influences outcome of opportunistic infections. Cell (2013) 0.95
Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. PLoS One (2013) 0.94
Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area. PLoS One (2012) 0.94
Identification and differentiation of clinically relevant mycobacterium species directly from acid-fast bacillus-positive culture broth. J Clin Microbiol (2009) 0.93
Multifunctional CD4 T cell responses in patients with active tuberculosis. Sci Rep (2012) 0.91
Development of an antibody to bovine IL-2 reveals multifunctional CD4 T(EM) cells in cattle naturally infected with bovine tuberculosis. PLoS One (2011) 0.91
Signatures of T cells as correlates of immunity to Francisella tularensis. PLoS One (2012) 0.90
A comparative analysis of polyfunctional T cells and secreted cytokines induced by Bacille Calmette-Guérin immunisation in children and adults. PLoS One (2012) 0.89
In vitro culture medium influences the vaccine efficacy of Mycobacterium bovis BCG. Vaccine (2011) 0.88
Multifunctional Analysis of CD4+ T-Cell Response as Immune-Based Model for Tuberculosis Detection. J Immunol Res (2015) 0.88
The glycosylated Rv1860 protein of Mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG. PLoS Pathog (2014) 0.88
Expansion of pathogen-specific mono- and multifunctional Th1 and Th17 cells in multi-focal tuberculous lymphadenitis. PLoS One (2013) 0.87
Diagnosing latent tuberculosis in high-risk individuals: rising to the challenge in high-burden areas. J Infect Dis (2011) 0.87
Combination of cytokine responses indicative of latent TB and active TB in Malawian adults. PLoS One (2013) 0.87
Immune responses to ESAT-6 and CFP-10 by FASCIA and multiplex technology for diagnosis of M. tuberculosis infection; IP-10 is a promising marker. PLoS One (2012) 0.86
Mycobacterium tuberculosis culture filtrate proteins plus CpG Oligodeoxynucleotides confer protection to Mycobacterium bovis BCG-primed mice by inhibiting interleukin-4 secretion. Infect Immun (2009) 0.86
Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort. PLoS One (2014) 0.86
Definition of CD4 Immunosignatures Associated with MTB. Front Immunol (2014) 0.85
Heparin-binding hemagglutinin induces IFN-γ(+) IL-2(+) IL-17(+) multifunctional CD4(+) T cells during latent but not active tuberculosis disease. Clin Vaccine Immunol (2012) 0.85
Immune subdominant antigens as vaccine candidates against Mycobacterium tuberculosis. J Immunol (2014) 0.84
Synthetic Long Peptide Derived from Mycobacterium tuberculosis Latency Antigen Rv1733c Protects against Tuberculosis. Clin Vaccine Immunol (2015) 0.83
Peripheral T cell cytokine responses for diagnosis of active tuberculosis. PLoS One (2012) 0.82
Comparing adjuvanted H28 and modified vaccinia virus ankara expressingH28 in a mouse and a non-human primate tuberculosis model. PLoS One (2013) 0.82
Protection against Mycobacterium tuberculosis infection offered by a new multistage subunit vaccine correlates with increased number of IFN-γ+ IL-2+ CD4+ and IFN-γ+ CD8+ T cells. PLoS One (2015) 0.82
A novel vaccine p846 encoding Rv3615c, Mtb10.4, and Rv2660c elicits robust immune response and alleviates lung injury induced by Mycobacterium infection. Hum Vaccin Immunother (2013) 0.81
CD4+ T cell polyfunctional profile in HIV-TB coinfection are similar between individuals with latent and active TB infection. Tuberculosis (Edinb) (2015) 0.81
Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study. BMC Infect Dis (2015) 0.80
Immunogenicity of BCG in HIV-exposed and non-exposed infants following routine birth or delayed vaccination. Int J Tuberc Lung Dis (2015) 0.80
Immune response to mycobacterial infection: lessons from flow cytometry. Clin Dev Immunol (2013) 0.79
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection. PLoS Pathog (2016) 0.77
Increased risk of incident osteoporosis and osteoporotic fracture in tuberculosis patients: a population-based study in a tuberculosis-endemic area. Osteoporos Int (2017) 0.77
Humanized NOG mice as a model for tuberculosis vaccine-induced immunity: a comparative analysis with the mouse and guinea pig models of tuberculosis. Immunology (2017) 0.76
Broad adaptive immune responses to M. tuberculosis antigens precede TST conversion in tuberculosis exposed household contacts in a TB-endemic setting. PLoS One (2014) 0.76
Treatment of latent tuberculosis infection induces changes in multifunctional Mycobacterium tuberculosis-specific CD4(+) T cells. Med Microbiol Immunol (2015) 0.76
Tuberculosis Therapy Modifies the Cytokine Profile, Maturation State, and Expression of Inhibitory Molecules on Mycobacterium tuberculosis-Specific CD4+ T-Cells. PLoS One (2016) 0.75
Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations. Tuberculosis (Edinb) (2016) 0.75
Multifunctional T Cell Response to DosR and Rpf Antigens Is Associated with Protection in Long-Term Mycobacterium tuberculosis-Infected Individuals in Colombia. Clin Vaccine Immunol (2016) 0.75
Heterologous boosting with recombinant VSV-846 in BCG-primed mice confers improved protection against Mycobacterium infection. Hum Vaccin Immunother (2016) 0.75
Combined antigen-specific interferon-γ and interleukin-2 release assay (FluoroSpot) for the diagnosis of Mycobacterium tuberculosis infection. PLoS One (2015) 0.75
DNA-Launched Alphavirus Replicons Encoding a Fusion of Mycobacterial Antigens Acr and Ag85B Are Immunogenic and Protective in a Murine Model of TB Infection. PLoS One (2015) 0.75
Analysis of Mycobacterium ulcerans-specific T-cell cytokines for diagnosis of Buruli ulcer disease and as potential indicator for disease progression. PLoS Negl Trop Dis (2017) 0.75
The Secreted Protein Rv1860 of Mycobacterium tuberculosis Stimulates Human Polyfunctional CD8+ T Cells. Clin Vaccine Immunol (2016) 0.75
Modulation of the immune response to Mycobacterium tuberculosis during malaria/M. tuberculosis co-infection. Clin Exp Immunol (2016) 0.75
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study. Lancet (2013) 14.06
Progression to active tuberculosis, but not transmission, varies by Mycobacterium tuberculosis lineage in The Gambia. J Infect Dis (2008) 3.15
Effectiveness of an early supplementation scheme of high-dose vitamin A versus standard WHO protocol in Gambian mothers and infants: a randomised controlled trial. Lancet (2007) 3.01
Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum. PLoS Med (2008) 3.01
Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian villagers. Clin Infect Dis (2006) 2.96
Immunogenicity and safety of a meningococcal A conjugate vaccine in Africans. N Engl J Med (2011) 2.72
The Global Enteric Multicenter Study (GEMS) of diarrheal disease in infants and young children in developing countries: epidemiologic and clinical methods of the case/control study. Clin Infect Dis (2012) 2.70
Large-scale evaluation of enzyme-linked immunospot assay and skin test for diagnosis of Mycobacterium tuberculosis infection against a gradient of exposure in The Gambia. Clin Infect Dis (2004) 2.62
Identifying recent adaptations in large-scale genomic data. Cell (2013) 2.57
Pneumococcal vaccination in developing countries. Lancet (2006) 2.45
Longitudinal assessment of an ELISPOT test for Mycobacterium tuberculosis infection. PLoS Med (2007) 2.36
How access to health care relates to under-five mortality in sub-Saharan Africa: systematic review. Trop Med Int Health (2010) 2.27
Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian infants: a longitudinal study. Clin Infect Dis (2008) 2.14
Reversion of the ELISPOT test after treatment in Gambian tuberculosis cases. BMC Infect Dis (2006) 2.12
Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clin Vaccine Immunol (2006) 1.99
Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum. Microbiology (2002) 1.97
Immunogenicity of the tuberculosis vaccine MVA85A is reduced by coadministration with EPI vaccines in a randomized controlled trial in Gambian infants. Sci Transl Med (2011) 1.94
Access to health care and mortality of children under 5 years of age in the Gambia: a case-control study. Bull World Health Organ (2009) 1.81
Incidence of tuberculosis and the predictive value of ELISPOT and Mantoux tests in Gambian case contacts. PLoS One (2008) 1.79
Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis. PLoS One (2011) 1.73
Bacteraemia in patients admitted to an urban hospital in West Africa. BMC Infect Dis (2007) 1.73
A decline in the incidence of invasive non-typhoidal Salmonella infection in The Gambia temporally associated with a decline in malaria infection. PLoS One (2010) 1.72
Quantitative T cell assay reflects infectious load of Mycobacterium tuberculosis in an endemic case contact model. Clin Infect Dis (2004) 1.71
Effect of micronutrient sprinkles on reducing anemia: a cluster-randomized effectiveness trial. Arch Pediatr Adolesc Med (2012) 1.68
Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa. Clin Vaccine Immunol (2009) 1.67
Serotype and antimicrobial susceptibility patterns of isolates of Streptococcus pneumoniae causing invasive disease in The Gambia 1996-2003. Trop Med Int Health (2006) 1.61
Comparison of enzyme-linked immunospot assay and tuberculin skin test in healthy children exposed to Mycobacterium tuberculosis. Pediatrics (2006) 1.56
Mycobacterium africanum elicits an attenuated T cell response to early secreted antigenic target, 6 kDa, in patients with tuberculosis and their household contacts. J Infect Dis (2006) 1.56
Risk factors for pulmonary tuberculosis: a clinic-based case control study in The Gambia. BMC Public Health (2006) 1.55
Effects of community-wide vaccination with PCV-7 on pneumococcal nasopharyngeal carriage in the Gambia: a cluster-randomized trial. PLoS Med (2011) 1.54
Transmission of Streptococcus pneumoniae in rural Gambian villages: a longitudinal study. Clin Infect Dis (2010) 1.52
Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian children who participated in a 9-valent pneumococcal conjugate vaccine trial and in their younger siblings. Pediatr Infect Dis J (2009) 1.52
Common variants at 11p13 are associated with susceptibility to tuberculosis. Nat Genet (2012) 1.52
Comparison of two interferon gamma release assays in the diagnosis of Mycobacterium tuberculosis infection and disease in The Gambia. BMC Infect Dis (2007) 1.48
The long-term natural history of trachomatous trichiasis in the Gambia. Invest Ophthalmol Vis Sci (2006) 1.46
Polyfunctional CD4(+) and CD8(+) T cell responses to tuberculosis antigens in HIV-1-infected patients before and after anti-retroviral treatment. J Immunol (2010) 1.45
Using ELISPOT to expose false positive skin test conversion in tuberculosis contacts. PLoS One (2007) 1.45
Infection with Helicobacter pylori is associated with protection against tuberculosis. PLoS One (2010) 1.45
Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment. PLoS One (2010) 1.44
Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent pneumococcal conjugate vaccine. BMC Infect Dis (2008) 1.43
Use of spoligotyping and large sequence polymorphisms to study the population structure of the Mycobacterium tuberculosis complex in a cohort study of consecutive smear-positive tuberculosis cases in The Gambia. J Clin Microbiol (2009) 1.41
Leprosy and the adaptation of human toll-like receptor 1. PLoS Pathog (2010) 1.41
A telemedicine service for HIV/AIDS physicians working in developing countries. J Telemed Telecare (2010) 1.38
Pre-vaccination nasopharyngeal pneumococcal carriage in a Nigerian population: epidemiology and population biology. PLoS One (2012) 1.37
Seasonality and outbreak of a predominant Streptococcus pneumoniae serotype 1 clone from The Gambia: expansion of ST217 hypervirulent clonal complex in West Africa. BMC Microbiol (2008) 1.35
Early acquisition and high nasopharyngeal co-colonisation by Streptococcus pneumoniae and three respiratory pathogens amongst Gambian new-borns and infants. BMC Infect Dis (2011) 1.31
Beyond good intentions: lessons on equipment donation from an African hospital. Bull World Health Organ (2008) 1.31
Incidence of tuberculosis and survival after its diagnosis in patients infected with HIV-1 and HIV-2. AIDS (2004) 1.26
Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa. PLoS One (2008) 1.25
Molecular epidemiology of community-acquired invasive non-typhoidal Salmonella among children aged 2 29 months in rural Gambia and discovery of a new serovar, Salmonella enterica Dingiri. J Med Microbiol (2007) 1.22
Evaluation of sequential multiplex PCR for direct detection of multiple serotypes of Streptococcus pneumoniae from nasopharyngeal secretions. J Med Microbiol (2009) 1.22
Screening for tuberculosis among 2381 household contacts of sputum-smear-positive cases in The Gambia. Trans R Soc Trop Med Hyg (2007) 1.22
Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design. Infect Immun (2004) 1.21
The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex. PLoS Negl Trop Dis (2012) 1.20
Early clinical trials with a new tuberculosis vaccine, MVA85A, in tuberculosis-endemic countries: issues in study design. Lancet Infect Dis (2006) 1.20
Bacterial infection and trachoma in the gambia: a case control study. Invest Ophthalmol Vis Sci (2007) 1.18
Conjunctival expression of matrix metalloproteinase and proinflammatory cytokine genes after trichiasis surgery. Invest Ophthalmol Vis Sci (2010) 1.16
Household concentrations and exposure of children to particulate matter from biomass fuels in The Gambia. Environ Sci Technol (2012) 1.14
The impact of vaccines on pneumonia: key lessons from Haemophilus influenzae type b conjugate vaccines. Vaccine (2008) 1.14
Mycobacterium africanum: a new opportunistic pathogen in HIV infection? AIDS (2005) 1.13
Commercial interferon gamma release assays compared to the tuberculin skin test for diagnosis of latent Mycobacterium tuberculosis infection in childhood contacts in the Gambia. Pediatr Infect Dis J (2010) 1.11
Impact, challenges, and future projections of vaccine trials in Africa. Am J Trop Med Hyg (2013) 1.10
Monitoring the introduction of pneumococcal conjugate vaccines into West Africa: design and implementation of a population-based surveillance system. PLoS Med (2012) 1.09
Production of TNF-alpha, IL-12(p40) and IL-17 can discriminate between active TB disease and latent infection in a West African cohort. PLoS One (2010) 1.09
Bacterial infections--a major cause of death among children in Africa. N Engl J Med (2005) 1.09
Tuberculosis case-contact research in endemic tropical settings: design, conduct, and relevance to other infectious diseases. Lancet Infect Dis (2010) 1.08
T cell memory response to pneumococcal protein antigens in an area of high pneumococcal carriage and disease. J Infect Dis (2009) 1.08
High granulocyte/lymphocyte ratio and paucity of NKT cells defines TB disease in a TB-endemic setting. Tuberculosis (Edinb) (2009) 1.07
ESAT-6/CFP-10 fusion protein and peptides for optimal diagnosis of mycobacterium tuberculosis infection by ex vivo enzyme-linked immunospot assay in the Gambia. J Clin Microbiol (2005) 1.05
Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection. Clin Vaccine Immunol (2007) 1.04
Predominant influence of environmental determinants on the persistence and avidity maturation of antibody responses to vaccines in infants. J Infect Dis (2006) 1.04
Adherence to isoniazid preventive therapy in Indonesian children: A quantitative and qualitative investigation. BMC Res Notes (2012) 1.02
C-reactive protein and procalcitonin in the evaluation of the efficacy of a pneumococcal conjugate vaccine in Gambian children. Trop Med Int Health (2008) 1.00