Published in Biol Psychiatry on February 28, 2009
The brain reward circuitry in mood disorders. Nat Rev Neurosci (2013) 3.08
Linking molecules to mood: new insight into the biology of depression. Am J Psychiatry (2010) 2.54
Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. J Neurosci (2009) 2.18
Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci U S A (2010) 2.17
IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity. J Neurosci (2011) 2.15
Neurobiology of resilience. Nat Neurosci (2012) 2.13
Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior. Biol Psychiatry (2010) 1.61
Behavioral and structural responses to chronic cocaine require a feedforward loop involving ΔFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell. J Neurosci (2013) 1.35
Animal models of depression: molecular perspectives. Curr Top Behav Neurosci (2011) 1.31
Structural and synaptic plasticity in stress-related disorders. Rev Neurosci (2011) 1.26
Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress. J Neurosci (2015) 1.10
Stress responses and the mesolimbic dopamine system: social contexts and sex differences. Horm Behav (2011) 1.06
Effects of inhibitor of κB kinase activity in the nucleus accumbens on emotional behavior. Neuropsychopharmacology (2012) 1.00
Sex, stress, and epigenetics: regulation of behavior in animal models of mood disorders. Biol Sex Differ (2013) 0.94
Sex differences in stress-induced social withdrawal: role of brain derived neurotrophic factor in the bed nucleus of the stria terminalis. Front Behav Neurosci (2014) 0.93
Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety-related behavior. Eur J Neurosci (2012) 0.93
Dendritic Spines in Depression: What We Learned from Animal Models. Neural Plast (2016) 0.92
Estrogen protects against the detrimental effects of repeated stress on glutamatergic transmission and cognition. Mol Psychiatry (2013) 0.91
Effects of estradiol on learned helplessness and associated remodeling of hippocampal spine synapses in female rats. Biol Psychiatry (2010) 0.89
Sex differences in mood disorders: perspectives from humans and rodent models. Biol Sex Differ (2014) 0.84
Peripheral and Central Mechanisms of Stress Resilience. Neurobiol Stress (2015) 0.84
Chronic unpredictable stress (CUS)-induced anxiety and related mood disorders in a zebrafish model: altered brain proteome profile implicates mitochondrial dysfunction. PLoS One (2013) 0.84
Pathogenesis of depression: Insights from human and rodent studies. Neuroscience (2015) 0.82
Role of the Brain's Reward Circuitry in Depression: Transcriptional Mechanisms. Int Rev Neurobiol (2015) 0.80
Sex differences in the neuro-immune consequences of stress: Focus on depression and anxiety. Brain Behav Immun (2017) 0.79
Integrative Analysis of Sex-Specific microRNA Networks Following Stress in Mouse Nucleus Accumbens. Front Mol Neurosci (2016) 0.75
Understanding the epigenetic basis of sex differences in depression. J Neurosci Res (2017) 0.75
Emerging Role for Nucleus Accumbens Medium Spiny Neuron Subtypes in Depression. Biol Psychiatry (2016) 0.75
Stress, sex, and motivated behaviors. J Neurosci Res (2017) 0.75
Establishment of a repeated social defeat stress model in female mice. Sci Rep (2017) 0.75
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nat Genet (2017) 0.75
Sex-specific transcriptional signatures in human depression. Nat Med (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation. Science (1997) 11.89
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science (2006) 9.31
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell (2007) 8.99
The mesolimbic dopamine reward circuit in depression. Biol Psychiatry (2006) 7.62
The many faces of CREB. Trends Neurosci (2005) 5.58
Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci (2002) 5.17
Rat toxicogenomic study reveals analytical consistency across microarray platforms. Nat Biotechnol (2006) 5.14
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron (2007) 4.96
Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology (Berl) (1997) 4.07
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci U S A (2002) 3.32
Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. J Neurosci (2001) 3.09
Chronic mild stress-induced anhedonia: a realistic animal model of depression. Neurosci Biobehav Rev (1992) 2.79
IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex. Mol Cell Biol (1999) 2.68
The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nat Neurosci (2008) 2.64
Statistical implications of pooling RNA samples for microarray experiments. BMC Bioinformatics (2003) 2.52
Sex differences and opposite effects of stress on dendritic spine density in the male versus female hippocampus. J Neurosci (2001) 2.37
Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biol Psychiatry (2006) 2.36
Gonadal steroid hormone receptors and sex differences in the hypothalamo-pituitary-adrenal axis. Horm Behav (1994) 2.29
Induction of deltaFosB in reward-related brain structures after chronic stress. J Neurosci (2004) 2.27
Constitutive nuclear factor-kappa B activity is required for central neuron survival. J Neurosci (2002) 1.95
A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior. Neuropsychopharmacology (2006) 1.90
Major depressive disorder. Neuron (2000) 1.79
Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression. Biol Psychiatry (2003) 1.78
Orexin signaling mediates the antidepressant-like effect of calorie restriction. J Neurosci (2008) 1.76
DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction. J Neurosci (2007) 1.74
Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect. Biol Psychiatry (2001) 1.53
Sex differences in the conditioned rewarding effects of cocaine. Brain Res (2003) 1.38
Effects of chronic restraint stress and estradiol on open field activity, spatial memory, and monoaminergic neurotransmitters in ovariectomized rats. Neuroscience (2002) 1.38
Overexpression of 5-HT1B receptor in dorsal raphe nucleus using Herpes Simplex Virus gene transfer increases anxiety behavior after inescapable stress. J Neurosci (2002) 1.32
Antianxiety and antidepressive behavior produced by physiological estradiol regimen may be modulated by hypothalamic-pituitary-adrenal axis activity. Neuropsychopharmacology (2005) 1.32
Gonadal hormones differentially modulate cocaine-induced conditioned place preference in male and female rats. Neuroscience (2003) 1.31
Gender and endogenous levels of estradiol do not influence adult hippocampal neurogenesis in mice. Hippocampus (2007) 1.30
Estradiol alleviates depressive-like symptoms in a novel animal model of post-partum depression. Behav Brain Res (2001) 1.30
Chronic stress and neural function: accounting for sex and age. J Neuroendocrinol (2007) 1.29
Sexually dimorphic effects of prenatal stress on cognition, hormonal responses, and central neurotransmitters. Endocrinology (2004) 1.27
Administration of estrogen receptor beta-specific selective estrogen receptor modulators to the hippocampus decrease anxiety and depressive behavior of ovariectomized rats. Pharmacol Biochem Behav (2006) 1.27
Sex differences in cocaine-stimulated motor behavior: disparate effects of gonadectomy. Neuropsychopharmacology (2001) 1.23
Stress and disease: is being female a predisposing factor? J Neurosci (2007) 1.18
From menarche to menopause: exploring the underlying biology of depression in women experiencing hormonal changes. Psychoneuroendocrinology (2007) 1.12
Estrogen alters behavior and forebrain c-fos expression in ovariectomized rats subjected to the forced swim test. Proc Natl Acad Sci U S A (1998) 1.11
Aged rats: sex differences and responses to chronic stress. Brain Res (2006) 1.03
Cognition, mood disorders, and sex hormones. ILAR J (2004) 1.02
Sex differences in the effects of two stress paradigms on dopaminergic neurotransmission. Physiol Behav (2007) 0.98
Sex differences and stress response of WKY rats. Physiol Behav (1993) 0.98
Stressor-induced anhedonia in the mesocorticolimbic system. Neurosci Biobehav Rev (1991) 0.98
Effect of neonatal handling and sex on basal and chronic stress-induced corticosterone and leptin secretion. Neuroendocrinology (2004) 0.90
Antidepressant-like actions of pregnancy, and progesterone in Wistar rats forced to swim. Psychoneuroendocrinology (2001) 0.87
Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility. Pharmacol Biochem Behav (2007) 0.84
Factors producing a menopausal depressive-like state in mice following ovariectomy. Psychopharmacology (Berl) (2006) 0.84
Nuclear factor kappa B in the dorsal raphe of macaques: an anatomical link for steroids, cytokines and serotonin. J Psychiatry Neurosci (2006) 0.84
Gene x environment effects: stress and memory dysfunctions caused by stress and gonadal factor irregularities during puberty in control and TGF-alpha hypomorphic mice. Neuropsychopharmacology (2007) 0.84
Psychiatric epidemiology--a historic review. Soc Psychiatry Psychiatr Epidemiol (1990) 0.82
Participation of the lateral septal nuclei (LSN) in the antidepressant-like actions of progesterone in the forced swimming test (FST). Behav Brain Res (2002) 0.81
Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci (2006) 12.37
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science (2006) 9.31
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell (2007) 8.99
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci (2006) 8.24
The molecular neurobiology of depression. Nature (2008) 6.51
Epigenetic regulation in psychiatric disorders. Nat Rev Neurosci (2007) 6.00
The many faces of CREB. Trends Neurosci (2005) 5.58
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (2010) 5.48
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron (2005) 5.09
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron (2007) 4.96
New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci (2006) 4.62
Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine. Science (2013) 4.60
Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nat Neurosci (2003) 4.60
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science (2010) 3.97
Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci U S A (2007) 3.92
Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory. Nat Neurosci (2007) 3.82
Psychobiology and molecular genetics of resilience. Nat Rev Neurosci (2009) 3.71
Transcriptional and epigenetic mechanisms of addiction. Nat Rev Neurosci (2011) 3.69
Neuronal competition and selection during memory formation. Science (2007) 3.48
DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses. Nat Neurosci (2010) 3.47
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci (2010) 3.41
Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc Natl Acad Sci U S A (2004) 3.37
Selective erasure of a fear memory. Science (2009) 3.34
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci U S A (2002) 3.32
Decoding the epigenetic language of neuronal plasticity. Neuron (2008) 3.23
Antidepressant actions of histone deacetylase inhibitors. J Neurosci (2009) 3.17
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature (2012) 3.15
The brain reward circuitry in mood disorders. Nat Rev Neurosci (2013) 3.08
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends Neurosci (2010) 3.02
Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron (2008) 3.01
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron (2009) 2.97
CREB modulates excitability of nucleus accumbens neurons. Nat Neurosci (2006) 2.95
Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc Natl Acad Sci U S A (2005) 2.95
Early life programming and neurodevelopmental disorders. Biol Psychiatry (2010) 2.93
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron (2008) 2.88
Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour. Nature (2003) 2.86
Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. J Neurosci (2010) 2.84
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. J Neurosci (2006) 2.75
IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nat Neurosci (2006) 2.71
DeltaFosB: a molecular switch for long-term adaptation in the brain. Brain Res Mol Brain Res (2004) 2.67
The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nat Neurosci (2008) 2.64
RGS9 modulates dopamine signaling in the basal ganglia. Neuron (2003) 2.61
A standardized protocol for repeated social defeat stress in mice. Nat Protoc (2011) 2.57
Linking molecules to mood: new insight into the biology of depression. Am J Psychiatry (2010) 2.54
Dysregulation of protein kinase a signaling in the aged prefrontal cortex: new strategy for treating age-related cognitive decline. Neuron (2003) 2.41
Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud. Dev Biol (2004) 2.39
Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood. Biol Psychiatry (2003) 2.37
Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biol Psychiatry (2006) 2.36