Published in Cell Metab on March 01, 2009
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Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nat Med (2010) 2.65
Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators. Immunity (2005) 2.56
PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Invest (2004) 2.56
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med (2012) 2.51
Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proc Natl Acad Sci U S A (2008) 2.49
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature (2009) 2.48
Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance. Cell Metab (2006) 2.37
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Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. J Clin Invest (2007) 2.23
Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes. J Clin Invest (2007) 2.17
SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nat Med (2007) 2.17
Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent manner. Hepatology (2012) 2.12
The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metab (2008) 2.09
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The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med (2008) 1.87
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Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity. Cell Metab (2006) 1.76
Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metab (2005) 1.73
Adipocyte CREB promotes insulin resistance in obesity. Cell Metab (2009) 1.72
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PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis. Proc Natl Acad Sci U S A (2009) 1.67
Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proc Natl Acad Sci U S A (2010) 1.60
CRTC3 links catecholamine signalling to energy balance. Nature (2010) 1.55
Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling. Cell Metab (2005) 1.43
Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature (2012) 1.42
Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency. Cell Metab (2010) 1.42
Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction. J Biol Chem (2006) 1.32
Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Mol Cell Biol (2002) 1.31
Induction of apoptosis by sphingoid long-chain bases in Aspergillus nidulans. Mol Cell Biol (2003) 1.28
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Korean red ginseng (Panax ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushima fatty rats. Metabolism (2009) 1.22
Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance. Hepatology (2011) 1.21
Reducing plasma membrane sphingomyelin increases insulin sensitivity. Mol Cell Biol (2011) 1.20
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Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is key regulator of hepatic gluconeogenesis. J Biol Chem (2012) 1.18
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Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling. Cell Metab (2006) 1.15
mTOR links incretin signaling to HIF induction in pancreatic beta cells. Proc Natl Acad Sci U S A (2011) 1.14
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A new grading system of lumbar central canal stenosis on MRI: an easy and reliable method. Skeletal Radiol (2011) 1.09
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