Published in J Invest Dermatol on March 05, 2009
Microbial symbiosis with the innate immune defense system of the skin. J Invest Dermatol (2011) 1.45
Antimicrobial peptides: old molecules with new ideas. J Invest Dermatol (2011) 1.34
RNase 7 contributes to the cutaneous defense against Enterococcus faecium. PLoS One (2009) 1.06
Interplay between Candida albicans and the antimicrobial peptide armory. Eukaryot Cell (2014) 0.92
Antimicrobial RNases of human skin. J Invest Dermatol (2009) 0.87
An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract. Kidney Int (2013) 0.86
DNase 2 is the main DNA-degrading enzyme of the stratum corneum. PLoS One (2011) 0.85
The Ribonuclease A Superfamily in Humans: Canonical RNases as the Buttress of Innate Immunity. Int J Mol Sci (2016) 0.80
Amplifying renal immunity: the role of antimicrobial peptides in pyelonephritis. Nat Rev Nephrol (2015) 0.80
RNase 7 in Cutaneous Defense. Int J Mol Sci (2016) 0.78
The Human Host Defense Ribonucleases 1, 3 and 7 Are Elevated in Patients with Sepsis after Major Surgery-A Pilot Study. Int J Mol Sci (2016) 0.76
A Review of Ribonuclease 7's Structure, Regulation, and Contributions to Host Defense. Int J Mol Sci (2016) 0.76
Exploring the mechanisms of action of human secretory RNase 3 and RNase 7 against Candida albicans. Microbiologyopen (2016) 0.76
Human Skin RNases Offer Dual Protection against Invading Bacteria. Front Microbiol (2017) 0.75
Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells. Sci Rep (2016) 0.75
Abundance of RNase4 and RNase5 mRNA and protein in host defence related tissues and secretions in cattle. Biochem Biophys Rep (2016) 0.75
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature (2007) 8.88
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection. Nat Immunol (2004) 3.19
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature (2005) 3.09
NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium. Infect Immun (2004) 2.47
miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging. Aging Cell (2010) 2.31
Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells. J Immunol (2008) 2.13
Human caspase 12 has acquired deleterious mutations. Biochem Biophys Res Commun (2002) 2.09
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. J Biol Chem (2005) 2.06
Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury. J Invest Dermatol (2010) 1.89
Increased sensitivity of histidinemic mice to UVB radiation suggests a crucial role of endogenous urocanic acid in photoprotection. J Invest Dermatol (2010) 1.78
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med (2011) 1.74
RNase 7 protects healthy skin from Staphylococcus aureus colonization. J Invest Dermatol (2010) 1.69
Epidermal EGFR controls cutaneous host defense and prevents inflammation. Sci Transl Med (2013) 1.69
Psoriasis: what we have learned from mouse models. Nat Rev Rheumatol (2010) 1.61
Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model. J Invest Dermatol (2010) 1.59
Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence. Dev Comp Immunol (2008) 1.55
Production of endogenous antibiotics in articular cartilage. Arthritis Rheum (2004) 1.55
Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease. Arthritis Res Ther (2008) 1.54
Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse. J Virol (2003) 1.48
Recombinant allergens promote expression of CD203c on basophils in sensitized individuals. J Allergy Clin Immunol (2002) 1.47
Organization and formation of the tight junction system in human epidermis and cultured keratinocytes. Eur J Cell Biol (2002) 1.45
Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am J Pathol (2002) 1.42
Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function. Am J Pathol (2011) 1.41
Cell death by cornification. Biochim Biophys Acta (2013) 1.40
Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid. J Invest Dermatol (2004) 1.35
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J Allergy Clin Immunol (2009) 1.31
Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair. Proc Natl Acad Sci U S A (2008) 1.29
Burkholderia is highly resistant to human Beta-defensin 3. Antimicrob Agents Chemother (2003) 1.29
Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins. J Leukoc Biol (2005) 1.26
Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract. Kidney Int (2011) 1.25
Fos and jun proteins are specifically expressed during differentiation of human keratinocytes. J Invest Dermatol (2005) 1.23
Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation. Cancer Res (2004) 1.23
Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection. BMC Infect Dis (2002) 1.20
Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2. Am J Pathol (2007) 1.20
The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption. J Invest Dermatol (2008) 1.18
Psoriasin (S100A7) is significantly up-regulated in human epithelial skin tumours. J Cancer Res Clin Oncol (2006) 1.15
Antimicrobial peptides in human skin. Chem Immunol Allergy (2005) 1.15
Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner. J Invest Dermatol (2002) 1.14
NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells. FASEB J (2009) 1.13
Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines. Eur Urol (2006) 1.12
Intravenous and intramyocardial injection of apoptotic white blood cell suspensions prevents ventricular remodelling by increasing elastin expression in cardiac scar tissue after myocardial infarction. Basic Res Cardiol (2011) 1.12
Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family. PLoS One (2009) 1.12
DNase1L2 degrades nuclear DNA during corneocyte formation. J Invest Dermatol (2006) 1.11
Primary sources and immunological prerequisites for sST2 secretion in humans. Cardiovasc Res (2010) 1.10
Relative contribution of intrinsic vs extrinsic factors to skin aging as determined by a validated skin age score. Arch Dermatol (2002) 1.09
Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells. Am J Pathol (2008) 1.09
Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. EMBO Mol Med (2014) 1.08
Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire. Mol Biol Evol (2008) 1.07
Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis. J Neuropathol Exp Neurol (2008) 1.07
Mouse beta-defensin-14, an antimicrobial ortholog of human beta-defensin-3. Antimicrob Agents Chemother (2008) 1.07
Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails. J Invest Dermatol (2011) 1.07
C5a stimulates production of plasminogen activator inhibitor-1 in human mast cells and basophils. Blood (2002) 1.06
RNase 7 contributes to the cutaneous defense against Enterococcus faecium. PLoS One (2009) 1.06
Pseudomonas aeruginosa- and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1. J Invest Dermatol (2006) 1.03
Flagellin is the principal inducer of the antimicrobial peptide S100A7c (psoriasin) in human epidermal keratinocytes exposed to Escherichia coli. FASEB J (2008) 1.03
Ultrasound affects distribution of plasminogen and tissue-type plasminogen activator in whole blood clots in vitro. Thromb Haemost (2004) 1.02
Human antimicrobial proteins effectors of innate immunity. J Endotoxin Res (2007) 1.02
High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan. Aging Cell (2013) 1.02
The skin surface as antimicrobial barrier: present concepts and future outlooks. Exp Dermatol (2012) 1.01
Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14. J Invest Dermatol (2010) 0.99
Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification? J Invest Dermatol (2010) 0.99
Interferon-alpha prevents apoptosis of endothelial cells after short-term exposure but induces replicative senescence after continuous stimulation. Lab Invest (2006) 0.99
Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study. Basic Res Cardiol (2011) 0.99
Epidermal proteases in the pathogenesis of rosacea. J Investig Dermatol Symp Proc (2011) 0.98
Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells. BMC Urol (2008) 0.98
Targeting miR-21 to treat psoriasis. Sci Transl Med (2014) 0.97
Gene silencing in a human organotypic skin model. Biochem Biophys Res Commun (2006) 0.96
Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function. FASEB J (2007) 0.96
Highly complex peptide aggregates of the S100 fused-type protein hornerin are present in human skin. J Invest Dermatol (2008) 0.95
Photooxidation generates biologically active phospholipids that induce heme oxygenase-1 in skin cells. J Biol Chem (2007) 0.95