Published in Am J Physiol Endocrinol Metab on March 10, 2009
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity. J Clin Invest (2011) 2.34
Retracted Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in tissues of DIO rats. Diabetes (2011) 1.50
Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise. Arthritis Rheum (2012) 1.29
Physical activity and inflammatory markers over 10 years: follow-up in men and women from the Whitehall II cohort study. Circulation (2012) 1.25
Exercise induced adipokine changes and the metabolic syndrome. J Diabetes Res (2014) 1.12
Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats. J Appl Physiol (1985) (2012) 1.08
Exercise, inflammation and aging. Aging Dis (2011) 1.02
Forced treadmill exercise training exacerbates inflammation and causes mortality while voluntary wheel training is protective in a mouse model of colitis. Brain Behav Immun (2013) 1.01
Exercise training effects on inflammatory gene expression in white adipose tissue of young mice. Mediators Inflamm (2012) 1.00
The effects of exercise modalities on adiposity in obese rats. Clinics (Sao Paulo) (2012) 0.97
Differential effect of weight loss with low-fat diet or high-fat diet restriction on inflammation in the liver and adipose tissue of mice with diet-induced obesity. Atherosclerosis (2011) 0.95
Adipose tissue and vascular phenotypic modulation by voluntary physical activity and dietary restriction in obese insulin-resistant OLETF rats. Am J Physiol Regul Integr Comp Physiol (2014) 0.95
Moderate exercise training provides modest protection against adipose tissue inflammatory gene expression in response to high-fat feeding. Physiol Rep (2014) 0.94
Galantamine alleviates inflammation and other obesity-associated complications in high-fat diet-fed mice. Mol Med (2011) 0.94
Exercise and gut immune function: evidence of alterations in colon immune cell homeostasis and microbiome characteristics with exercise training. Immunol Cell Biol (2015) 0.93
Lipidomics analysis reveals efficient storage of hepatic triacylglycerides enriched in unsaturated fatty acids after one bout of exercise in mice. PLoS One (2010) 0.93
Benefits of exercise training on breast cancer progression and inflammation in C3(1)SV40Tag mice. Cytokine (2011) 0.93
Exercise training protects against an acute inflammatory insult in mouse epididymal adipose tissue. J Appl Physiol (1985) (2014) 0.92
Calorie restriction and endurance exercise share potent anti-inflammatory function in adipose tissues in ameliorating diet-induced obesity and insulin resistance in mice. Nutr Metab (Lond) (2010) 0.91
The effects of exercise training on obesity-induced dysregulated expression of adipokines in white adipose tissue. Int J Endocrinol (2013) 0.90
Differential effects of calorie restriction and exercise on the adipose transcriptome in diet-induced obese mice. J Obes (2011) 0.88
Effects of voluntary wheel running on LPS-induced sickness behavior in aged mice. Brain Behav Immun (2012) 0.86
Retracted Hepatic glucagon action is essential for exercise-induced reversal of mouse fatty liver. Diabetes (2011) 0.85
Prolonged exposure to GH impairs insulin signaling in the heart. J Mol Endocrinol (2011) 0.83
Overnutrition stimulates intestinal epithelium proliferation through β-catenin signaling in obese mice. Diabetes (2013) 0.82
Targeting adipose tissue inflammation to treat the underlying basis of the metabolic complications of obesity. Nestle Nutr Inst Workshop Ser (2012) 0.81
Retention of sedentary obese visceral white adipose tissue phenotype with intermittent physical activity despite reduced adiposity. Am J Physiol Regul Integr Comp Physiol (2015) 0.81
Putative factors that may modulate the effect of exercise on liver fat: insights from animal studies. J Nutr Metab (2011) 0.80
Physical training prevents body weight gain but does not modify adipose tissue gene expression. Braz J Med Biol Res (2012) 0.79
Prior exercise training blunts short-term high-fat diet-induced weight gain. Am J Physiol Regul Integr Comp Physiol (2016) 0.79
Ultraviolet B irradiation reduces the expression of adiponectin in ovarial adipose tissues through endocrine actions of calcitonin gene-related peptide-induced serum amyloid A. PLoS One (2014) 0.79
Childhood obesity: immune response and nutritional approaches. Front Immunol (2015) 0.79
Effect of endurance training on retinol-binding protein 4 gene expression and its protein level in adipose tissue and the liver in diabetic rats induced by a high-fat diet and streptozotocin. J Diabetes Investig (2014) 0.78
Endurance interval training in obese mice reduces muscle inflammation and macrophage content independently of weight loss. Physiol Rep (2014) 0.78
Endurance and Resistance Training Affect High Fat Diet-Induced Increase of Ceramides, Inflammasome Expression, and Systemic Inflammation in Mice. J Diabetes Res (2015) 0.78
Mitochondrial biogenesis in adipose tissue: can exercise make fat cells 'fit'? J Physiol (2009) 0.77
High intensity interval training improves liver and adipose tissue insulin sensitivity. Mol Metab (2015) 0.77
Exercise training attenuates neutrophil infiltration and elastase expression in adipose tissue of high-fat-diet-induced obese mice. Physiol Rep (2015) 0.77
Effects of exercise and diet composition on expression of MCP-1 and oxidative stress-related mRNA of adipose tissue in diet-induced obese mice. J Exerc Nutrition Biochem (2013) 0.77
Comparison of Diet versus Exercise on Metabolic Function and Gut Microbiota in Obese Rats. Med Sci Sports Exerc (2016) 0.77
Moderate exercise training is more effective than resveratrol supplementation for ameliorating lipid metabolic complication in skeletal muscle of high fat diet-induced obese mice. J Exerc Nutrition Biochem (2015) 0.76
Exercise and Estrogen Make Fat Cells "Fit". Exerc Sport Sci Rev (2015) 0.76
Preventive and improvement effects of exercise training and supplement intake in white adipose tissues on obesity and lifestyle-related diseases. Environ Health Prev Med (2012) 0.76
Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging. Physiol Rep (2016) 0.76
Moderate intensity exercise inhibits macrophage infiltration and attenuates adipocyte inflammation in ovariectomized rats. J Exerc Nutrition Biochem (2014) 0.76
Head to Head Comparison of Short-Term Treatment with the NAD(+) Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice. Front Pharmacol (2016) 0.75
Diet affects arctic ground squirrel gut microbial metatranscriptome independent of community structure. Environ Microbiol (2017) 0.75
Impact of Exercise on Innate Immunity in Multiple Sclerosis Progression and Symptomatology. Front Physiol (2016) 0.75
Physical training improves body weight and energy balance but does not protect against hepatic steatosis in obese mice. Int J Clin Exp Med (2015) 0.75
Exercise Training Attenuates the Dysregulated Expression of Adipokines and Oxidative Stress in White Adipose Tissue. Oxid Med Cell Longev (2017) 0.75
The Potential Role of Aerobic Exercise-Induced Pentraxin 3 on Obesity-Related Inflammation and Metabolic Dysregulation. Mediators Inflamm (2017) 0.75
Anti-inflammatory effects of exercise training in adipose tissue do not require FGF21. J Endocrinol (2017) 0.75
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia (1985) 109.13
Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest (2007) 20.19
The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology (2005) 15.74
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest (2006) 12.32
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab (2008) 5.10
Emerging role of adipose tissue hypoxia in obesity and insulin resistance. Int J Obes (Lond) (2008) 3.17
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J Clin Invest (1994) 3.16
Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia (2006) 2.88
Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects. Am J Physiol Endocrinol Metab (2005) 2.77
The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. Clin Chem (2008) 2.72
Visceral fat: a key mediator of steatohepatitis in metabolic liver disease. Hepatology (2008) 2.70
Metabolic obesity: the paradox between visceral and subcutaneous fat. Curr Diabetes Rev (2006) 2.53
Blood glucose area under the curve. Methodological aspects. Diabetes Care (1990) 2.46
Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice. Am J Physiol Endocrinol Metab (2008) 1.96
The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control. Essays Biochem (2006) 1.86
Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS Med (2006) 1.81
Systemic low-grade inflammation is related to both circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women. Int J Obes Relat Metab Disord (2004) 1.76
Inducible Toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue. Obesity (Silver Spring) (2008) 1.63
Peroxisome proliferator-activated receptor alpha protects against obesity-induced hepatic inflammation. Endocrinology (2007) 1.54
Oxygen consumption in adult and AGED C57BL/6J mice during acute treadmill exercise of different intensity. Exp Gerontol (1998) 1.53
Comparative evaluation of simple indices of insulin resistance. Metabolism (2004) 1.42
Modulation of C-reactive protein, tumor necrosis factor-alpha, and adiponectin by diet, exercise, and weight loss. J Nutr (2008) 1.29
Concurrent exercise prevents high-fat-diet-induced macrovesicular hepatic steatosis. J Appl Physiol (1985) (2003) 1.29
Association of 1-y changes in diet pattern with cardiovascular disease risk factors and adipokines: results from the 1-y randomized Oslo Diet and Exercise Study. Am J Clin Nutr (2008) 1.20
Exercise, inflammation, and innate immunity. Neurol Clin (2006) 1.14
Physical activity guidelines for Americans. Okla Nurse (2008) 1.09
Effects of chronic exercise on cytokine production in white adipose tissue and skeletal muscle of rats. Cytokine (2007) 1.07
Exercise training decreases expression of inflammation-related adipokines through reduction of oxidative stress in rat white adipose tissue. Biochem Biophys Res Commun (2009) 1.06
Elevated sialic acid, but not CRP, predicts features of the metabolic syndrome independently of BMI in women. Int J Obes Relat Metab Disord (2004) 0.96
Reduction in trunk fat predicts cardiovascular exercise training-related reductions in C-reactive protein. Brain Behav Immun (2009) 0.92
Hepatic steatosis and plasma dyslipidemia induced by a high-sucrose diet are corrected by an acute leptin infusion. J Appl Physiol (1985) (2007) 0.92
Improved fibrinolytic activity during exercise may be an effect of the adipocyte-derived hormones leptin and adiponectin. Thromb Res (2008) 0.91
Dieting is more effective in reducing weight but exercise is more effective in reducing fat during the early phase of a weight-reducing program in healthy humans. J Nutr Biochem (2003) 0.89
The effects of moderate physical exercise on cardiac hypertrophy in interleukin 6 deficient mice. Adv Med Sci (2007) 0.88
Carbohydrate versus energy restriction: effects on weight loss, body composition and metabolism. Ann Nutr Metab (2007) 0.88
[Adiponectin: a new link between obesity, insulin resistance and cardiovascular disease]. Med Clin (Barc) (2005) 0.86
Nutrition in pathophysiology and treatment of nonalcoholic fatty liver disease. Curr Opin Clin Nutr Metab Care (2008) 0.82
Cognitive and behavioral approaches in the treatment of obesity. Endocrinol Metab Clin North Am (2008) 0.81
Vigorous physical activity and cytokines in adolescents. Eur J Appl Physiol (2008) 0.79
Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A (2011) 9.57
Position statement. Part one: Immune function and exercise. Exerc Immunol Rev (2011) 3.69
Brain-derived neurotrophic factor is associated with age-related decline in hippocampal volume. J Neurosci (2010) 1.90
A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells. Am J Physiol Cell Physiol (2012) 1.62
Postexercise hypotension in an endurance-trained population of men and women following high-intensity interval and steady-state cycling. Am J Hypertens (2010) 1.52
Exercise and respiratory tract viral infections. Exerc Sport Sci Rev (2009) 1.49
Adiposity, activity, fitness, and C-reactive protein in children. Med Sci Sports Exerc (2010) 1.49
Effects of diet and/or exercise on the adipocytokine and inflammatory cytokine levels of postmenopausal women with type 2 diabetes. Metabolism (2005) 1.46
Reduced work capacity in individuals with Down syndrome: a consequence of autonomic dysfunction? Exerc Sport Sci Rev (2013) 1.46
Endurance exercise training raises high-density lipoprotein cholesterol and lowers small low-density lipoprotein and very low-density lipoprotein independent of body fat phenotypes in older men and women. Metabolism (2007) 1.44
Exergaming and older adult cognition: a cluster randomized clinical trial. Am J Prev Med (2012) 1.42
Angiotensinogen M235T polymorphism associates with exercise hemodynamics in postmenopausal women. Physiol Genomics (2002) 1.40
Racial differences in central blood pressure and vascular function in young men. Am J Physiol Heart Circ Physiol (2008) 1.35
Neurobiological markers of exercise-related brain plasticity in older adults. Brain Behav Immun (2012) 1.31
Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior. Brain Behav Immun (2008) 1.30
Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue. J Lipid Res (2012) 1.26
High-density lipoprotein-cholesterol, its subfractions, and responses to exercise training are dependent on endothelial lipase genotype. Metabolism (2003) 1.19
Resistance exercise training reduces central blood pressure and improves microvascular function in African American and white men. Atherosclerosis (2009) 1.18
Endurance training improves post-exercise cardiac autonomic modulation in obese women with and without type 2 diabetes. Eur J Appl Physiol (2007) 1.15
The phytoestrogen genistein induces thymic and immune changes: a human health concern? Proc Natl Acad Sci U S A (2002) 1.14
Effects of diet and exercise on metabolic disturbances in high-fat diet-fed mice. Cytokine (2009) 1.12
Muscle quality, aerobic fitness and fat mass predict lower-extremity physical function in community-dwelling older adults. Gerontology (2007) 1.09
Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition. Mol Neurodegener (2014) 1.08
Exercise accelerates cutaneous wound healing and decreases wound inflammation in aged mice. Am J Physiol Regul Integr Comp Physiol (2007) 1.08
Exercise, inflammation and aging. Aging Dis (2011) 1.02
C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men. Am J Physiol Regul Integr Comp Physiol (2009) 1.01
Forced treadmill exercise training exacerbates inflammation and causes mortality while voluntary wheel training is protective in a mouse model of colitis. Brain Behav Immun (2013) 1.01
Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis. J Mol Endocrinol (2006) 1.01
Exercise training effects on inflammatory gene expression in white adipose tissue of young mice. Mediators Inflamm (2012) 1.00
Mouse testing methods in psychoneuroimmunology: an overview of how to measure sickness, depressive/anxietal, cognitive, and physical activity behaviors. Methods Mol Biol (2012) 0.95
Moderate exercise protects mice from death due to influenza virus. Brain Behav Immun (2005) 0.95
Moderate exercise early after influenza virus infection reduces the Th1 inflammatory response in lungs of mice. Exerc Immunol Rev (2006) 0.95
Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults. Metabolism (2008) 0.94
Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice. Psychoneuroendocrinology (2013) 0.94
Sex differences in the relationship between obesity, C-reactive protein, physical activity, depression, sleep quality and fatigue in older adults. Brain Behav Immun (2008) 0.94
Efficacy of β-hydroxy-β-methylbutyrate supplementation in elderly and clinical populations. Nutrition (2012) 0.93
Lower extremity muscle quality and gait variability in older adults. Age Ageing (2012) 0.93
Higher antibody, but not cell-mediated, responses to vaccination in high physically fit elderly. J Appl Physiol (1985) (2006) 0.93
Impaired vagal modulation of heart rate in individuals with Down syndrome. Clin Auton Res (2005) 0.92
Stronger relationship between central adiposity and C-reactive protein in older women than men. Menopause (2009) 0.92
Catecholamine response to maximal exercise in persons with Down syndrome. Am J Cardiol (2008) 0.88
Effects of a Taiji and Qigong intervention on the antibody response to influenza vaccine in older adults. Am J Chin Med (2007) 0.87
Exercise delays allogeneic tumor growth and reduces intratumoral inflammation and vascularization. J Appl Physiol (1985) (2004) 0.87
Sex impacts the relation between body composition and physical function in older adults. Menopause (2009) 0.87
Effects of voluntary wheel running on LPS-induced sickness behavior in aged mice. Brain Behav Immun (2012) 0.86
The effect of progressive resistance training on leg strength, aerobic capacity and functional tasks of daily living in persons with Down syndrome. Disabil Rehabil (2011) 0.86
The effect of acute fish-oil supplementation on endothelial function and arterial stiffness following a high-fat meal. Appl Physiol Nutr Metab (2010) 0.86
Independent relationship between heart rate recovery and C-reactive protein in older adults. J Am Geriatr Soc (2007) 0.85
Adiposity and aerobic fitness are associated with metabolic disease risk in children. Appl Physiol Nutr Metab (2011) 0.85
Autonomic responses to physiological stressors in women with type 2 diabetes. Clin Auton Res (2008) 0.85
Blunted heart rate response to upright tilt in people with Down syndrome. Arch Phys Med Rehabil (2005) 0.84
Beta2- and beta3-adrenergic receptor polymorphisms and exercise hemodynamics in postmenopausal women. J Appl Physiol (1985) (2004) 0.84
Physical fitness predicts functional tasks in individuals with Down syndrome. Med Sci Sports Exerc (2010) 0.84
Macrophages from alpha 7 nicotinic acetylcholine receptor knockout mice demonstrate increased cholesterol accumulation and decreased cellular paraoxonase expression: a possible link between the nervous system and atherosclerosis development. Biochem Biophys Res Commun (2009) 0.83
Association of pro12Ala polymorphism in the peroxisome proliferative-activated receptor gamma2 gene with obesity and hypertension in Korean women. J Nutr Sci Vitaminol (Tokyo) (2007) 0.83
Vascular dysfunction and physical activity in multiple sclerosis. Med Sci Sports Exerc (2012) 0.83
The associations of adiposity, physical activity and inflammation with fatigue in older adults. Brain Behav Immun (2011) 0.83
Effects of protein intake and gender on body composition changes: a randomized clinical weight loss trial. Nutr Metab (Lond) (2012) 0.83
Exercise training improves cardiovascular autonomic modulation in response to glucose ingestion in obese adults with and without type 2 diabetes mellitus. Metabolism (2009) 0.83
ACE insertion/deletion polymorphism and submaximal exercise hemodynamics in postmenopausal women. J Appl Physiol (1985) (2002) 0.83
Autonomic response to upright tilt in people with and without Down syndrome. Res Dev Disabil (2010) 0.83
Hemodynamic and arterial stiffness differences between African-Americans and Caucasians after maximal exercise. Am J Physiol Heart Circ Physiol (2013) 0.82
Exercise speeds cutaneous wound healing in high-fat diet-induced obese mice. Med Sci Sports Exerc (2012) 0.82
Baroreflex sensitivity during static exercise in individuals with Down Syndrome. Med Sci Sports Exerc (2005) 0.82
Case study: Natural bodybuilding contest preparation. Int J Sport Nutr Exerc Metab (2014) 0.81
Relation of heart rate recovery after exercise to C-reactive protein and white blood cell count. Am J Cardiol (2007) 0.81
NK-cells have an impaired response to acute exercise and a lower expression of the inhibitory receptors KLRG1 and CD158a in humans with latent cytomegalovirus infection. Brain Behav Immun (2011) 0.81
The effects of a glucose load and sympathetic challenge on autonomic function in obese women with and without type 2 diabetes mellitus. Metabolism (2007) 0.81
Complexity of force output during static exercise in individuals with Down syndrome. J Appl Physiol (1985) (2009) 0.81
Impact of training modality on strength and physical function in older adults. Gerontology (2009) 0.81
An exploratory study of cardiac function and oxygen uptake during cycle ergometry in overweight children. Obesity (Silver Spring) (2007) 0.81
Validity of predicting left ventricular end systolic pressure changes following an acute bout of exercise. J Sci Med Sport (2012) 0.80
Impaired postexercise cardiovascular autonomic modulation in middle-aged women with type 2 diabetes. Eur J Cardiovasc Prev Rehabil (2007) 0.80
Voluntary wheel running does not affect lipopolysaccharide-induced depressive-like behavior in young adult and aged mice. Neuroimmunomodulation (2013) 0.80
Resting metabolic rate is not reduced in obese adults with Down syndrome. Ment Retard (2005) 0.79
Breast tumors induced by N-methyl-N-nitrosourea are damaging to bone strength, structure, and mineralization in the absence of metastasis in rats. J Bone Miner Res (2011) 0.79
Intestinal and systemic immune development and response to vaccination are unaffected by dietary (1,3/1,6)-β-D-glucan supplementation in neonatal piglets. Clin Vaccine Immunol (2012) 0.79
Influence of arterial wave reflection on carotid blood pressure and intima-media thickness in older endurance trained men and women with pre-hypertension. Clin Physiol Funct Imaging (2009) 0.79
Effects of a traditional Taiji/Qigong curriculum on older adults' immune response to influenza vaccine. Med Sport Sci (2008) 0.79
Heart rate complexity in response to upright tilt in persons with Down syndrome. Res Dev Disabil (2011) 0.79
Normal HR with tilt, yet autonomic dysfunction in persons with Down syndrome. Med Sci Sports Exerc (2015) 0.78
Exercise training improves hemodynamic recovery to isometric exercise in obese men with type 2 diabetes but not in obese women. Metabolism (2012) 0.78
Microvascular function and ageing L-arginine, tetrahydrobiopterin and the search for the fountain of vascular youth. J Physiol (2008) 0.78
Resveratrol supplementation reduces aortic atherosclerosis and calcification and attenuates loss of aerobic capacity in a mouse model of uremia. J Med Food (2014) 0.78
Dietary whole glucan particles do not affect antibody or cell-mediated immune responses to influenza virus vaccination in mice. Immunol Invest (2011) 0.78
Using reactive hyperemia to assess the efficacy of local cooling on reducing sacral skin ischemia under surface pressure in people with spinal cord injury: a preliminary report. Arch Phys Med Rehabil (2013) 0.78
Cardiac autonomic control in individuals with Down syndrome. Am J Ment Retard (2006) 0.78