Published in Cell Microbiol on March 12, 2009
Non-toxigenic Clostridium sordellii: clinical and microbiological features of a case of cholangitis-associated bacteremia. Anaerobe (2011) 0.93
Serine-71 phosphorylation of Rac1 modulates downstream signaling. PLoS One (2012) 0.84
Comparative analysis of the extracellular proteomes of two Clostridium sordellii strains exhibiting contrasting virulence. Anaerobe (2010) 0.81
Role of p38alpha/beta MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B. Toxins (Basel) (2016) 0.75
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol (2009) 3.66
Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins. Microbiol Mol Biol Rev (2004) 2.60
Genotyping and phenotyping of beta2-toxigenic Clostridium perfringens fecal isolates associated with gastrointestinal diseases in piglets. J Clin Microbiol (2003) 1.32
Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol (2005) 1.28
Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism. J Biol Chem (2011) 1.27
The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cells. PLoS Pathog (2009) 1.26
Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors. Mol Cell Biol (2003) 1.22
Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes. Mol Biol Cell (2003) 1.18
Organization and regulation of the neurotoxin genes in Clostridium botulinum and Clostridium tetani. Anaerobe (2004) 1.16
Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors. J Cell Biol (2006) 1.11
Receptor-mediated transcytosis of botulinum neurotoxin A through intestinal cell monolayers. Cell Microbiol (2007) 1.10
Rho GTPases link cytoskeletal rearrangements and activation processes induced via the tetraspanin CD82 in T lymphocytes. J Cell Sci (2002) 1.09
Cyclic AMP induces morphological changes of vascular smooth muscle cells by inhibiting a Rac-dependent signaling pathway. J Cell Physiol (2005) 1.09
Expression of botulinum neurotoxins A and E, and associated non-toxin genes, during the transition phase and stability at high temperature: analysis by quantitative reverse transcription-PCR. Microbiology (2006) 1.09
Clostridium perfringens epsilon toxin: a malevolent molecule for animals and man? Toxins (Basel) (2013) 1.08
Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies. FEBS Lett (2004) 1.07
Interaction of Clostridium perfringens iota-toxin with lipid bilayer membranes. Demonstration of channel formation by the activated binding component Ib and channel block by the enzyme component Ia. J Biol Chem (2001) 1.07
Expression of cnf1 by Escherichia coli J96 involves a large upstream DNA region including the hlyCABD operon, and is regulated by the RfaH protein. Mol Microbiol (2003) 1.06
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability. Am J Pathol (2007) 1.06
BotR/A and TetR are alternative RNA polymerase sigma factors controlling the expression of the neurotoxin and associated protein genes in Clostridium botulinum type A and Clostridium tetani. Mol Microbiol (2005) 1.06
Detection by PCR-enzyme-linked immunosorbent assay of Clostridium botulinum in fish and environmental samples from a coastal area in northern France. Appl Environ Microbiol (2002) 1.05
Bacterial protein toxins and lipids: pore formation or toxin entry into cells. Biol Cell (2006) 1.03
Regulation of toxin and bacteriocin gene expression in Clostridium by interchangeable RNA polymerase sigma factors. Mol Microbiol (2006) 1.02
A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity. J Biol Chem (2004) 1.02
Clostridium difficile toxin B causes apoptosis in epithelial cells by thrilling mitochondria. Involvement of ATP-sensitive mitochondrial potassium channels. J Biol Chem (2007) 1.02
Clostridium perfringens epsilon toxin rapidly decreases membrane barrier permeability of polarized MDCK cells. Cell Microbiol (2003) 1.01
Clostridium perfringens delta toxin is sequence related to beta toxin, NetB, and Staphylococcus pore-forming toxins, but shows functional differences. PLoS One (2008) 1.01
Quantitative profiling of the detergent-resistant membrane proteome of iota-b toxin induced vero cells. J Proteome Res (2005) 1.00
Effect of epsilon toxin-GFP on MDCK cells and renal tubules in vivo. J Histochem Cytochem (2004) 0.98
Clostridium perfringens iota toxin: characterization of the cell-associated iota b complex. Biochem J (2002) 0.98
Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity. PLoS One (2010) 0.97
Binding of epsilon-toxin from Clostridium perfringens in the nervous system. Vet Microbiol (2008) 0.97
Genetic relatedness of Clostridium difficile isolates from various origins determined by triple-locus sequence analysis based on toxin regulatory genes tcdC, tcdR, and cdtR. J Clin Microbiol (2008) 0.96
Differential Involvement of ERK2 and p38 in platelet adhesion to collagen. J Biol Chem (2005) 0.95
Rac GTPase plays an essential role in exocytosis by controlling the fusion competence of release sites. J Neurosci (2002) 0.94
Differential requirement for the translocation of clostridial binary toxins: iota toxin requires a membrane potential gradient. FEBS Lett (2007) 0.94
Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors. Trends Cell Biol (2012) 0.94
Regulated expression of the beta2-toxin gene (cpb2) in Clostridium perfringens type a isolates from horses with gastrointestinal diseases. J Clin Microbiol (2005) 0.94
Detergent-resistant membrane microdomains facilitate Ib oligomer formation and biological activity of Clostridium perfringens iota-toxin. Infect Immun (2004) 0.93
Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release. PLoS One (2010) 0.93
Endocytosis and toxicity of clostridial binary toxins depend on a clathrin-independent pathway regulated by Rho-GDI. Cell Microbiol (2010) 0.92
Differential entry of botulinum neurotoxin A into neuronal and intestinal cells. Cell Microbiol (2008) 0.92
Purification and characterization of a UDP-glucosyltransferase produced by Legionella pneumophila. Infect Immun (2003) 0.91
Identification of the channel-forming domain of Clostridium perfringens Epsilon-toxin (ETX). Biochim Biophys Acta (2009) 0.91
Observing the confinement potential of bacterial pore-forming toxin receptors inside rafts with nonblinking Eu(3+)-doped oxide nanoparticles. Biophys J (2012) 0.91
Two-component systems are involved in the regulation of botulinum neurotoxin synthesis in Clostridium botulinum type A strain Hall. PLoS One (2012) 0.90
Clostridium perfringens iota toxin. Mapping of the Ia domain involved in docking with Ib and cellular internalization. J Biol Chem (2002) 0.90
Rac1 inactivation by lethal toxin from Clostridium sordellii modifies focal adhesions upstream of actin depolymerization. Cell Microbiol (2009) 0.89
Modification of epithelial cell barrier permeability and intercellular junctions by Clostridium sordellii lethal toxins. Cell Microbiol (2006) 0.89
Tailored ß-cyclodextrin blocks the translocation pores of binary exotoxins from C. botulinum and C. perfringens and protects cells from intoxication. PLoS One (2011) 0.89
Clostridium septicum alpha-toxin forms pores and induces rapid cell necrosis. Toxicon (2009) 0.89
Membrane Interaction of botulinum neurotoxin A translocation (T) domain. The belt region is a regulatory loop for membrane interaction. J Biol Chem (2008) 0.88
Distribution of Clostridium perfringens epsilon toxin in the brains of acutely intoxicated mice and its effect upon glial cells. Toxicon (2007) 0.88
Transcytosis of iota-toxin across polarized CaCo-2 cells. Mol Microbiol (2002) 0.87
Aeromonas exoenzyme T of Aeromonas salmonicida is a bifunctional protein that targets the host cytoskeleton. J Biol Chem (2007) 0.87
The long-lived nature of clostridium perfringens iota toxin in mammalian cells induces delayed apoptosis. Infect Immun (2009) 0.86
Preferential entry of botulinum neurotoxin A Hc domain through intestinal crypt cells and targeting to cholinergic neurons of the mouse intestine. PLoS Pathog (2012) 0.86
RhoA GTPase and F-actin dynamically regulate the permeability of Cx43-made channels in rat cardiac myocytes. J Biol Chem (2008) 0.86
Clostridial binary toxins: iota and C2 family portraits. Front Cell Infect Microbiol (2011) 0.86
CD44 Promotes intoxication by the clostridial iota-family toxins. PLoS One (2012) 0.85
Haemorrhagic toxin and lethal toxin from Clostridium sordellii strain vpi9048: molecular characterization and comparative analysis of substrate specificity of the large clostridial glucosylating toxins. Cell Microbiol (2014) 0.85
Production and characterisation of a neutralising chimeric antibody against botulinum neurotoxin A. PLoS One (2010) 0.85
Attack of the nervous system by Clostridium perfringens Epsilon toxin: from disease to mode of action on neural cells. Toxicon (2013) 0.84
Antibiotic-induced expression of a cryptic cpb2 gene in equine beta2-toxigenic Clostridium perfringens. Mol Microbiol (2005) 0.82
Interactions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins. Biophys J (2012) 0.82
Evidence that membrane rafts are not required for the action of Clostridium perfringens enterotoxin. Infect Immun (2008) 0.81
Involvement of a small GTP binding protein in HIV-1 release. Retrovirology (2005) 0.81
Fast changes in the functional status of release sites during short-term plasticity: involvement of a frequency-dependent bypass of Rac at Aplysia synapses. J Physiol (2007) 0.81
Epsilon toxin from Clostridium perfringens acts on oligodendrocytes without forming pores, and causes demyelination. Cell Microbiol (2014) 0.80
Bacterial protein toxins and lipids: role in toxin targeting and activity. Biol Cell (2006) 0.80
Characterization of botulinum neurotoxin type A subtypes by immunocapture enrichment and liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem (2015) 0.80
Cross-reactivity of anthrax and C2 toxin: protective antigen promotes the uptake of botulinum C2I toxin into human endothelial cells. PLoS One (2011) 0.80
Rapid quantification of clostridial epsilon toxin in complex food and biological matrixes by immunopurification and ultraperformance liquid chromatography-tandem mass spectrometry. Anal Chem (2012) 0.79
Residues involved in the pore-forming activity of the Clostridium perfringens iota toxin. Cell Microbiol (2014) 0.79
Structural Insights into Clostridium perfringens Delta Toxin Pore Formation. PLoS One (2013) 0.79
[Botulism: the agent, mode of action of the botulinum neurotoxins, forms of acquisition, treatment and prevention]. C R Biol (2002) 0.79
Detection and quantification of botulinum neurotoxin type a by a novel rapid in vitro fluorimetric assay. Appl Environ Microbiol (2009) 0.79
Challenging the roles of CD44 and lipolysis stimulated lipoprotein receptor in conveying Clostridium perfringens iota toxin cytotoxicity in breast cancer. Mol Cancer (2014) 0.78
Molecular characterization of Clostridium difficile clinical isolates in a geriatric hospital. J Med Microbiol (2007) 0.78
An atypical Clostridium strain related to the Clostridium botulinum group III strain isolated from a human blood culture. J Clin Microbiol (2013) 0.78
The large clostridial toxins from Clostridium sordellii and C. difficile repress glucocorticoid receptor activity. Infect Immun (2007) 0.78
Crystallization and preliminary X-ray diffraction studies of delta-toxin from Clostridium perfringens. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.78
Degeneration and regeneration of murine skeletal neuromuscular junctions after intramuscular injection with a sublethal dose of Clostridium sordellii lethal toxin. Infect Immun (2004) 0.78
Characterization of the enzymatic activity of Clostridium perfringens TpeL. Toxicon (2013) 0.77
Regulation of toxin synthesis in Clostridium botulinum and Clostridium tetani. Toxicon (2013) 0.77
Clostridium celerecrescens, often misidentified as "Clostridium clostridioforme group," is involved in rare human infection cases. Diagn Microbiol Infect Dis (2012) 0.75