Published in Cell Cycle on May 02, 2009
DNA resection in eukaryotes: deciding how to fix the break. Nat Struct Mol Biol (2010) 2.81
CtIP links DNA double-strand break sensing to resection. Mol Cell (2009) 2.11
Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Mol Cell (2012) 1.91
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol (2009) 1.65
DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints. Trends Cell Biol (2010) 1.44
Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells. Cell Cycle (2012) 1.03
CtIP mediates replication fork recovery in a FANCD2-regulated manner. Hum Mol Genet (2014) 1.01
Prognostic value of CtIP/RBBP8 expression in breast cancer. Cancer Med (2013) 0.87
Joint surveillance of the replication foci by PCNA and CtIP. Cell Cycle (2009) 0.75
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science (2002) 6.32
Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells. Proc Natl Acad Sci U S A (2005) 1.91
Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts. Cancer Res (2002) 1.60
BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks. J Biol Chem (2002) 1.50
Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1. Cancer Res (2003) 1.36
NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage. J Biol Chem (2003) 1.34
Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. J Biol Chem (2002) 1.34
Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature. Cancer Cell (2006) 1.24
Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Res (2008) 1.23
Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality. J Biol Chem (2009) 1.23
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control. Cell Cycle (2008) 1.18
Retracted STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage. J Cell Sci (2005) 1.17
Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability. Cancer Res (2002) 1.12
NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response. Cancer Res (2004) 1.10
Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR. Cell Cycle (2011) 1.01
Purified human SUV3p exhibits multiple-substrate unwinding activity upon conformational change. Biochemistry (2004) 1.01
NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response. J Biol Chem (2002) 1.00
A novel role of the chromokinesin Kif4A in DNA damage response. Cell Cycle (2008) 0.97
Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability. Mol Cancer (2011) 0.96
A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia. EMBO Mol Med (2013) 0.95
Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. J Exp Med (2012) 0.95
Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J Med Chem (2009) 0.95
NFBD1/Mdc1 mediates ATR-dependent DNA damage response. Cancer Res (2005) 0.91
Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation. J Biol Chem (2011) 0.83
Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice. Cancer Res (2002) 0.82
Structural requirements of chromokinesin Kif4A for its proper function in mitosis. Biochem Biophys Res Commun (2008) 0.80
Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37. Front Biosci (2008) 0.78