Published in Am J Respir Cell Mol Biol on April 03, 2009
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. J Clin Invest (2012) 1.82
Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source. Proc Natl Acad Sci U S A (2012) 1.62
HB-EGF protects the lungs after intestinal ischemia/reperfusion injury. J Surg Res (2010) 1.51
Deficits in lung alveolarization and function after systemic maternal inflammation and neonatal hyperoxia exposure. J Appl Physiol (1985) (2010) 1.46
Neonatal oxygen adversely affects lung function in adult mice without altering surfactant composition or activity. Am J Physiol Lung Cell Mol Physiol (2009) 1.41
Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice. Part Fibre Toxicol (2011) 1.33
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis. J Allergy Clin Immunol (2013) 1.16
Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography. PLoS One (2012) 1.14
Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness. Respir Res (2010) 1.09
IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung. Nanotoxicology (2012) 1.09
Long-term nose-only cigarette smoke exposure induces emphysema and mild skeletal muscle dysfunction in mice. Dis Model Mech (2012) 1.08
Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model. Part Fibre Toxicol (2011) 1.03
Selective targeting of TGF-β activation to treat fibroinflammatory airway disease. Sci Transl Med (2014) 1.00
Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metab (2013) 1.00
The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis. PLoS One (2013) 0.96
The protease allergen Pen c 13 induces allergic airway inflammation and changes in epithelial barrier integrity and function in a murine model. J Biol Chem (2011) 0.95
Choice of mouse strain influences the outcome in a mouse model of chemical-induced asthma. PLoS One (2010) 0.95
Airway delivery of soluble factors from plastic-adherent bone marrow cells prevents murine asthma. Am J Respir Cell Mol Biol (2011) 0.95
Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis. Toxicol Sci (2012) 0.93
The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease. PLoS One (2011) 0.92
Electroporation-mediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusion. J Trauma Acute Care Surg (2012) 0.92
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success. J Thorac Dis (2012) 0.91
Modeling the influence of vitamin D deficiency on cigarette smoke-induced emphysema. Front Physiol (2013) 0.90
Diesel exhaust particulates exacerbate asthma-like inflammation by increasing CXC chemokines. Am J Pathol (2011) 0.90
Prolonged injury and altered lung function after ozone inhalation in mice with chronic lung inflammation. Am J Respir Cell Mol Biol (2012) 0.90
Lung-specific loss of the laminin α3 subunit confers resistance to mechanical injury. J Cell Sci (2011) 0.89
Pulmonary toxicity of instilled silver nanoparticles: influence of size, coating and rat strain. PLoS One (2015) 0.89
Static and dynamic mechanics of the murine lung after intratracheal bleomycin. BMC Pulm Med (2011) 0.87
Podocalyxin regulates murine lung vascular permeability by altering endothelial cell adhesion. PLoS One (2014) 0.87
Longitudinal in vivo microcomputed tomography of mouse lungs: No evidence for radiotoxicity. Am J Physiol Lung Cell Mol Physiol (2015) 0.85
Increased phospholipase A2 and lyso-phosphatidylcholine levels are associated with surfactant dysfunction in lung contusion injury in mice. Surgery (2012) 0.85
Pulmonary abnormalities in mice with paracoccidioidomycosis: a sequential study comparing high resolution computed tomography and pathologic findings. PLoS Negl Trop Dis (2010) 0.85
Neuroimmune semaphorin 4A as a drug and drug target for asthma. Int Immunopharmacol (2013) 0.83
Intravenous and intratracheal mesenchymal stromal cell injection in a mouse model of pulmonary emphysema. COPD (2013) 0.83
Xiao-Qing-Long-Tang shows preventive effect of asthma in an allergic asthma mouse model through neurotrophin regulation. BMC Complement Altern Med (2013) 0.82
Free DNA in cystic fibrosis airway fluids correlates with airflow obstruction. Mediators Inflamm (2015) 0.81
Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice. PLoS One (2012) 0.81
Vitamin D deficiency exacerbates COPD-like characteristics in the lungs of cigarette smoke-exposed mice. Respir Res (2015) 0.81
Alternative splicing and tissue-specific elastin misassembly act as biological modifiers of human elastin gene frameshift mutations associated with dominant cutis laxa. J Biol Chem (2012) 0.81
Herbal medicine treatment reduces inflammation in a murine model of cockroach allergen-induced asthma. Ann Allergy Asthma Immunol (2011) 0.81
Cellular senescence mediates fibrotic pulmonary disease. Nat Commun (2017) 0.81
Deficiency of the two-pore-domain potassium channel TREK-1 promotes hyperoxia-induced lung injury. Crit Care Med (2014) 0.80
Assessment of murine lung mechanics outcome measures: alignment with those made in asthmatics. Front Physiol (2013) 0.80
Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan. Am J Physiol Lung Cell Mol Physiol (2012) 0.80
Alveolar macrophage depletion increases the severity of acute inflammation following nonlethal unilateral lung contusion in mice. J Trauma Acute Care Surg (2014) 0.80
Airway-parenchymal interdependence. Compr Physiol (2012) 0.80
B-lymphocytes as key players in chemical-induced asthma. PLoS One (2013) 0.79
Persistence of asthmatic response after ammonium persulfate-induced occupational asthma in mice. PLoS One (2014) 0.78
Development and characterization of a long-term murine model of Streptococcus pneumoniae infection of the lower airways. Infect Immun (2014) 0.78
Early pulmonary events of nose-only water pipe (shisha) smoking exposure in mice. Physiol Rep (2015) 0.78
Enhancement of methacholine-evoked tracheal contraction induced by bacterial lipopolysaccharides depends on epithelium and tumor necrosis factor. J Allergy (Cairo) (2012) 0.78
Cardiopulmonary and histological characterization of an acute rat lung injury model demonstrating safety of mesenchymal stromal cell infusion. Cytotherapy (2016) 0.77
Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo. Fibrogenesis Tissue Repair (2014) 0.77
Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis. Respir Res (2015) 0.77
Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation. Mol Immunol (2013) 0.77
Sulfatases are determinants of alveolar formation. Matrix Biol (2012) 0.77
Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice. Sci Data (2016) 0.76
Inhalation toxicology methods: the generation and characterization of exposure atmospheres and inhalational exposures. Curr Protoc Toxicol (2015) 0.75
Role of IL-17A in murine models of COPD airway disease. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Benefits of 21% Oxygen Compared with 100% Oxygen for Delivery of Isoflurane to Mice (Mus musculus) and Rats (Rattus norvegicus). J Am Assoc Lab Anim Sci (2017) 0.75
X-Ray based Lung Function measurement-a sensitive technique to quantify lung function in allergic airway inflammation mouse models. Sci Rep (2016) 0.75
Effects of antenatal lipopolysaccharide and postnatal hyperoxia on airway reactivity and remodeling in a neonatal mouse model. Pediatr Res (2015) 0.75
Perinatal Immunization With Vaccine-Grade Listeria monocytogenes Provides Protection Against Murine Th2 Airway Inflammation. Allergy Asthma Immunol Res (2014) 0.75
Persistence of respiratory and inflammatory responses after dermal sensitization to persulfate salts in a mouse model of non-atopic asthma. Allergy Asthma Clin Immunol (2016) 0.75
Restrictive Lung Disease in the Cu/Zn Superoxide-Dismutase 1 G93A Amyotrophic Lateral Sclerosis Mouse Model. Am J Respir Cell Mol Biol (2017) 0.75
Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma. Acta Pharmacol Sin (2012) 0.75
Regulation of allergic lung inflammation by endothelial cell transglutaminase 2. Am J Physiol Lung Cell Mol Physiol (2015) 0.75
Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury. J Transl Med (2016) 0.75
Disruption of the Hepcidin/Ferroportin Regulatory System Causes Pulmonary Iron Overload and Restrictive Lung Disease. EBioMedicine (2017) 0.75
Posttreatment with Protectin DX ameliorates bleomycin-induced pulmonary fibrosis and lung dysfunction in mice. Sci Rep (2017) 0.75
Standardized Herbal Formula PM014 Inhibits Radiation-Induced Pulmonary Inflammation in Mice. Sci Rep (2017) 0.75
Nitric oxide prevents alveolar senescence and emphysema in a mouse model. PLoS One (2015) 0.75
Mechanical Stimulation by Postnasal Drip Evokes Cough. PLoS One (2015) 0.75
Combined Effects of in Utero and Adolescent Tobacco Smoke Exposure on Lung Function in C57Bl/6J Mice. Environ Health Perspect (2016) 0.75
IL-13 is a central mediator of chemical-induced airway hyperreactivity in mice. PLoS One (2017) 0.75
Receptor for advanced glycation end-products and World Trade Center particulate induced lung function loss: A case-cohort study and murine model of acute particulate exposure. PLoS One (2017) 0.75
Airway smooth muscle dysfunction in Pompe (Gaa-/-) mice. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model. Sci Rep (2017) 0.75
Effects of diesel exhaust particle exposure on a murine model of asthma due to soybean. PLoS One (2017) 0.75
A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med (2008) 17.19
Withdrawal of inhaled glucocorticoids and exacerbations of COPD. N Engl J Med (2014) 6.29
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat Med (2002) 5.10
Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax (2009) 4.86
Chronic obstructive pulmonary disease. Lancet (2012) 4.43
High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med (2012) 3.99
Public health importance of triggers of myocardial infarction: a comparative risk assessment. Lancet (2011) 3.81
Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 3.58
Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med (2009) 3.43
Office spirometry significantly improves early detection of COPD in general practice: the DIDASCO Study. Chest (2004) 3.09
Cardiovascular safety of tiotropium in patients with COPD. Chest (2009) 2.70
Resistance training prevents deterioration in quadriceps muscle function during acute exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 2.59
Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2009) 2.55
The sequential changes in myocardial thickness and thickening which occur during acute transmural infarction, infarct reperfusion and the resultant expression of reperfusion injury. Eur Heart J (2004) 2.25
Physical activity and hospitalization for exacerbation of COPD. Chest (2006) 2.24
Use of circulating galactomannan screening for early diagnosis of invasive aspergillosis in allogeneic stem cell transplant recipients. J Infect Dis (2002) 2.22
Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation (2003) 2.12
Ultrafine particles affect experimental thrombosis in an in vivo hamster model. Am J Respir Crit Care Med (2002) 2.06
Physical inactivity in patients with COPD, a controlled multi-center pilot-study. Respir Med (2010) 2.06
Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice. Circulation (2009) 2.05
Preventing COPD exacerbations with macrolides: a review and budget impact analysis. Respir Med (2013) 2.05
Minimal clinically important differences in pharmacological trials. Am J Respir Crit Care Med (2014) 2.00
Intermittent spontaneous breathing protects the rat diaphragm from mechanical ventilation effects. Crit Care Med (2005) 2.00
Pulmonary rehabilitation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 1.97
Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study. Crit Care (2010) 1.85
Impact of a stepwise introduction of smoke-free legislation on the rate of preterm births: analysis of routinely collected birth data. BMJ (2013) 1.85
Risk factors and comorbidities in the preclinical stages of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 1.78
The maximum uptake of (18)F-deoxyglucose on positron emission tomography scan correlates with survival, hypoxia inducible factor-1alpha and GLUT-1 in non-small cell lung cancer. Eur J Cancer (2007) 1.76
Leupeptin inhibits ventilator-induced diaphragm dysfunction in rats. Am J Respir Crit Care Med (2007) 1.74
An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 1.73
Childhood asthma and environmental exposures at swimming pools: state of the science and research recommendations. Environ Health Perspect (2008) 1.71
Differential effects of progenitor cell populations on left ventricular remodeling and myocardial neovascularization after myocardial infarction. J Am Coll Cardiol (2010) 1.70
Possible mechanisms of the cardiovascular effects of inhaled particles: systemic translocation and prothrombotic effects. Toxicol Lett (2004) 1.70
Are patients with COPD more active after pulmonary rehabilitation? Chest (2008) 1.69
Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med (2009) 1.63
An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2015) 1.63
The impact of traffic air pollution on bronchiolitis obliterans syndrome and mortality after lung transplantation. Thorax (2011) 1.62
Hypogonadism, quadriceps weakness, and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 1.61
N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation. Crit Care Med (2011) 1.54
Vitamin D supplementation did not prevent influenza-like illness as diagnosed retrospectively by questionnaires in subjects participating in randomized clinical trials. Scand J Infect Dis (2011) 1.52
Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction. Crit Care Med (2012) 1.51
Nicotine activates the chemosensory cation channel TRPA1. Nat Neurosci (2009) 1.44
Adverse health effects of child labor: high exposure to chromium and oxidative DNA damage in children manufacturing surgical instruments. Environ Health Perspect (2012) 1.44
Optimization of local methylprednisolone delivery to inhibit inflammatory reaction and neointimal hyperplasia of coated coronary stents. J Invasive Cardiol (2002) 1.44
Interleukin-6 causes myocardial failure and skeletal muscle atrophy in rats. Circulation (2005) 1.40
Activity monitoring for assessment of physical activities in daily life in patients with chronic obstructive pulmonary disease. Arch Phys Med Rehabil (2005) 1.39
Exacerbation frequency and course of COPD. Int J Chron Obstruct Pulmon Dis (2012) 1.38
Sevoflurane exposure prevents diaphragmatic oxidative stress during mechanical ventilation but reduces force and affects protein metabolism even during spontaneous breathing in a rat model. Anesth Analg (2015) 1.38
Gender differences in the management and experience of Chronic Obstructive Pulmonary Disease. Respir Med (2004) 1.37
The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema. Am J Respir Crit Care Med (2009) 1.36
External aortic root support: a histological and mechanical study in sheep. Interact Cardiovasc Thorac Surg (2013) 1.35
Expert elicitation on ultrafine particles: likelihood of health effects and causal pathways. Part Fibre Toxicol (2009) 1.35
Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge. Environ Health Perspect (2008) 1.32
Tiotropium HandiHaler in the treatment of COPD: a safety review. Int J Chron Obstruct Pulmon Dis (2009) 1.32
Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis. Toxicol Appl Pharmacol (2003) 1.30
Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters: role of histamine. Am J Respir Crit Care Med (2003) 1.29
Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation. Crit Care Med (2009) 1.26
Pharmacological stabilization of mast cells abrogates late thrombotic events induced by diesel exhaust particles in hamsters. Circulation (2004) 1.25
Daily physical activity in subjects with newly diagnosed COPD. Thorax (2013) 1.24
Detrimental effects of short-term mechanical ventilation on diaphragm function and IGF-I mRNA in rats. Intensive Care Med (2003) 1.24
The role of bronchodilator treatment in the prevention of exacerbations of COPD. Eur Respir J (2012) 1.23
Chronic obstructive pulmonary disease and comorbidities. Lancet Respir Med (2013) 1.19
Inhospital management of COPD exacerbations: a systematic review of the literature with regard to adherence to international guidelines. J Eval Clin Pract (2009) 1.16
Subclinical responses in healthy cyclists briefly exposed to traffic-related air pollution: an intervention study. Environ Health (2010) 1.15
Rocuronium exacerbates mechanical ventilation-induced diaphragm dysfunction in rats. Crit Care Med (2006) 1.15
Particulate matter in the environment: pulmonary and cardiovascular effects. Curr Opin Pulm Med (2007) 1.15
Quantification of lung fibrosis and emphysema in mice using automated micro-computed tomography. PLoS One (2012) 1.14
Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice. Toxicol Sci (2004) 1.14
Effects of particulate air pollution on hemostasis. Clin Occup Environ Med (2006) 1.14
Acetaminophen decreases intracellular glutathione levels and modulates cytokine production in human alveolar macrophages and type II pneumocytes in vitro. Int J Biochem Cell Biol (2005) 1.14
Concentration response functions for ultrafine particles and all-cause mortality and hospital admissions: results of a European expert panel elicitation. Environ Sci Technol (2010) 1.12
High human exposure to cobalt and other metals in Katanga, a mining area of the Democratic Republic of Congo. Environ Res (2009) 1.12
Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance. Eur Heart J (2008) 1.11
A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ. Antimicrob Agents Chemother (2013) 1.11
Air pollution related prothrombotic changes in persons with diabetes. Environ Health Perspect (2010) 1.11