Published in Crit Care Med on December 01, 2006
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Mechanical ventilation induces diaphragmatic mitochondrial dysfunction and increased oxidant production. Free Radic Biol Med (2009) 1.50
Prolonged mechanical ventilation alters diaphragmatic structure and function. Crit Care Med (2009) 1.41
Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse. Am J Respir Crit Care Med (2010) 1.16
Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis. FASEB J (2011) 1.15
Effects of acute administration of corticosteroids during mechanical ventilation on rat diaphragm. Am J Respir Crit Care Med (2008) 1.09
Diaphragm muscle weakness in an experimental porcine intensive care unit model. PLoS One (2011) 1.03
Plasma from septic shock patients induces loss of muscle protein. Crit Care (2011) 0.96
Clinical review: Acute respiratory distress syndrome - clinical ventilator management and adjunct therapy. Crit Care (2013) 0.96
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Titin-based mechanosensing and signaling: role in diaphragm atrophy during unloading? Am J Physiol Lung Cell Mol Physiol (2010) 0.82
Bench-to-bedside review: Diaphragm muscle function in disuse and acute high-dose corticosteroid treatment. Crit Care (2009) 0.81
Recent advances in mechanical ventilation in patients without acute respiratory distress syndrome. F1000Prime Rep (2014) 0.79
A fresh look at paralytics in the critically ill: real promise and real concern. Ann Intensive Care (2012) 0.78
Therapeutic range of spontaneous breathing during mechanical ventilation. Anesthesiology (2014) 0.76
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Muscle weakness after administration of neuromuscular blocking agents: do not immobilize the diaphragm unnecessarily. Crit Care Med (2007) 0.75
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Kinetics of ventilation-induced changes in diaphragmatic metabolism by bilateral phrenic pacing in a piglet model. Sci Rep (2016) 0.75
Critical illness-associated diaphragm weakness. Intensive Care Med (2017) 0.75
The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells. J Anesth (2012) 0.75
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A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med (2008) 17.19
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell (2006) 12.72
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature (2006) 9.31
Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation. Genome Res (2003) 7.86
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. N Engl J Med (2005) 6.33
Withdrawal of inhaled glucocorticoids and exacerbations of COPD. N Engl J Med (2014) 6.29
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell (2008) 5.47
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer (2006) 4.92
Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax (2009) 4.86
A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. Science (2009) 4.16
Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol (2013) 4.04
High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med (2012) 3.99
Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants. Gastroenterology (2005) 3.90
Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer. Proc Natl Acad Sci U S A (2007) 3.84
Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 3.58
A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nat Biotechnol (2009) 3.44
Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med (2009) 3.43
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A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A (2012) 2.85
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat Genet (2011) 2.74
Cardiovascular safety of tiotropium in patients with COPD. Chest (2009) 2.70
DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes Dev (2008) 2.60
Resistance training prevents deterioration in quadriceps muscle function during acute exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 2.59
Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening. Cancer Cell (2011) 2.56
Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2009) 2.55
Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. Cancer Cell (2009) 2.54
gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease. Science (2009) 2.43
Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases. Am J Respir Cell Mol Biol (2009) 2.26
Physical activity and hospitalization for exacerbation of COPD. Chest (2006) 2.24
Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate. Clin Cancer Res (2006) 2.23
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23. Nat Genet (2002) 2.23
Physical inactivity in patients with COPD, a controlled multi-center pilot-study. Respir Med (2010) 2.06
Preventing COPD exacerbations with macrolides: a review and budget impact analysis. Respir Med (2013) 2.05
Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme. Clin Cancer Res (2008) 2.04
HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. Int J Radiat Oncol Biol Phys (2002) 2.00
Intermittent spontaneous breathing protects the rat diaphragm from mechanical ventilation effects. Crit Care Med (2005) 2.00
Minimal clinically important differences in pharmacological trials. Am J Respir Crit Care Med (2014) 2.00
Pulmonary rehabilitation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 1.97
Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes. Lancet Oncol (2011) 1.95
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes Dev (2010) 1.95
MYC high level gene amplification is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema. Am J Pathol (2009) 1.92
Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study. Crit Care (2010) 1.85
Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. Proc Natl Acad Sci U S A (2005) 1.82
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma. Sci Transl Med (2011) 1.79
Risk factors and comorbidities in the preclinical stages of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 1.78
DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours. Histopathology (2010) 1.78
Cyfip1 is a putative invasion suppressor in epithelial cancers. Cell (2009) 1.77
Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell (2003) 1.76
Leupeptin inhibits ventilator-induced diaphragm dysfunction in rats. Am J Respir Crit Care Med (2007) 1.74
An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 1.73
Are patients with COPD more active after pulmonary rehabilitation? Chest (2008) 1.69
Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients. Hum Mol Genet (2006) 1.68
Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity. J Pathol (2004) 1.65
Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med (2009) 1.63
An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2015) 1.63
Towards patient-based cancer therapeutics. Nat Biotechnol (2010) 1.63
Hypogonadism, quadriceps weakness, and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 1.61
Tight glycemic control protects the myocardium and reduces inflammation in neonatal heart surgery. Ann Thorac Surg (2010) 1.59
PRCC-TFE3 renal carcinomas: morphologic, immunohistochemical, ultrastructural, and molecular analysis of an entity associated with the t(X;1)(p11.2;q21). Am J Surg Pathol (2002) 1.59
N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation. Crit Care Med (2011) 1.54
Performance analysis of interactive multimodal CME retraining on attitude toward and application of OPCAB. J Thorac Cardiovasc Surg (2006) 1.52
Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction. Crit Care Med (2012) 1.51
Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials. J Clin Oncol (2010) 1.48
Clustering of deletions on chromosome 13 in benign and low-malignant lipomatous tumors. Int J Cancer (2003) 1.45
Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: a report of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer (2002) 1.45
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. Arch Neurol (2007) 1.42
HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB. Mol Cancer Res (2007) 1.42
Identification of driver genes in hepatocellular carcinoma by exome sequencing. Hepatology (2013) 1.41
Clinicopathologic and molecular genetic characterization of low-grade fibromyxoid sarcoma, and cloning of a novel FUS/CREB3L1 fusion gene. Lab Invest (2005) 1.41
Interleukin-6 causes myocardial failure and skeletal muscle atrophy in rats. Circulation (2005) 1.40
Activity monitoring for assessment of physical activities in daily life in patients with chronic obstructive pulmonary disease. Arch Phys Med Rehabil (2005) 1.39
Exacerbation frequency and course of COPD. Int J Chron Obstruct Pulmon Dis (2012) 1.38
Sevoflurane exposure prevents diaphragmatic oxidative stress during mechanical ventilation but reduces force and affects protein metabolism even during spontaneous breathing in a rat model. Anesth Analg (2015) 1.38
Near-infrared spectroscopy for monitoring spinal cord ischemia during hybrid thoracoabdominal aortic aneurysm repair. J Endovasc Ther (2011) 1.38
Gender differences in the management and experience of Chronic Obstructive Pulmonary Disease. Respir Med (2004) 1.37
Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors. Genes Chromosomes Cancer (2011) 1.36
The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema. Am J Respir Crit Care Med (2009) 1.36
EWSR1-CREB1 and EWSR1-ATF1 fusion genes in angiomatoid fibrous histiocytoma. Clin Cancer Res (2007) 1.33
Tiotropium HandiHaler in the treatment of COPD: a safety review. Int J Chron Obstruct Pulmon Dis (2009) 1.32
Neuronal inclusion protein TDP-43 has no primary genetic role in FTD and ALS. Neurobiol Aging (2008) 1.31
Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor. Genes Chromosomes Cancer (2013) 1.29
Array CGH analysis in primary gastrointestinal stromal tumors: cytogenetic profile correlates with anatomic site and tumor aggressiveness, irrespective of mutational status. Genes Chromosomes Cancer (2007) 1.27
Accuracy of MRI in characterization of soft tissue tumors and tumor-like lesions. A prospective study in 548 patients. Eur Radiol (2004) 1.26
Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation. Crit Care Med (2009) 1.26