Published in Angew Chem Int Ed Engl on January 01, 2009
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med (2010) 27.12
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell (2007) 4.71
Retracted DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol (2007) 4.45
Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III trial. Lancet Oncol (2009) 3.69
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature (2003) 3.49
The Selaginella genome identifies genetic changes associated with the evolution of vascular plants. Science (2011) 3.10
Retracted DNA demethylation in hormone-induced transcriptional derepression. Nature (2009) 2.90
Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice. Nat Med (2005) 2.59
Visualization by comprehensive microarray analysis of gene expression programs during transdifferentiation of mesophyll cells into xylem cells. Proc Natl Acad Sci U S A (2002) 2.05
Active trifluoromethylating agents from well-defined Copper(I)-CF3 complexes. J Am Chem Soc (2008) 1.89
Phase II trial of amrubicin for treatment of refractory or relapsed small-cell lung cancer: Thoracic Oncology Research Group Study 0301. J Clin Oncol (2006) 1.88
Computed tomography findings in pathological usual interstitial pneumonia: relationship to survival. Am J Respir Crit Care Med (2007) 1.85
Suppressive function of androgen receptor in bone resorption. Proc Natl Acad Sci U S A (2003) 1.72
Spectroscopic characterization of a hydroperoxo-heme intermediate: conversion of a side-on peroxo to an end-on hydroperoxo complex. Angew Chem Int Ed Engl (2009) 1.71
A functional [NiFe]hydrogenase mimic that catalyzes electron and hydride transfer from H2. Science (2013) 1.63
Vascular-related NAC-DOMAIN7 is involved in the differentiation of all types of xylem vessels in Arabidopsis roots and shoots. Plant J (2008) 1.62
Prediction of coronary artery disease in patients undergoing carotid endarterectomy. J Neurosurg (2005) 1.55
Brain masculinization requires androgen receptor function. Proc Natl Acad Sci U S A (2004) 1.51
A low-spin ruthenium(IV)-oxo complex: does the spin state have an impact on the reactivity? Angew Chem Int Ed Engl (2010) 1.48
Overexpression of miR165 affects apical meristem formation, organ polarity establishment and vascular development in Arabidopsis. Plant Cell Physiol (2007) 1.47
Immunoglobulin G4-related lung disease: clinicoradiological and pathological features. Respirology (2013) 1.47
Premature ovarian failure in androgen receptor-deficient mice. Proc Natl Acad Sci U S A (2005) 1.44
ANXUR1 and 2, sister genes to FERONIA/SIRENE, are male factors for coordinated fertilization. Curr Biol (2009) 1.44
VND-INTERACTING2, a NAC domain transcription factor, negatively regulates xylem vessel formation in Arabidopsis. Plant Cell (2010) 1.44
A peroxide bridge between Fe and Cu ions in the O2 reduction site of fully oxidized cytochrome c oxidase could suppress the proton pump. Proc Natl Acad Sci U S A (2009) 1.37
R1R2R3-Myb proteins positively regulate cytokinesis through activation of KNOLLE transcription in Arabidopsis thaliana. Development (2007) 1.36
Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell proliferation and alters leaf shape in Arabidopsis thaliana. Plant J (2004) 1.34
Axial ligand effects on the geometric and electronic structures of nonheme oxoiron(IV) complexes. J Am Chem Soc (2008) 1.32
Central control of bone remodeling by neuromedin U. Nat Med (2007) 1.32
Late onset of obesity in male androgen receptor-deficient (AR KO) mice. Biochem Biophys Res Commun (2003) 1.30
Efficacy of inhaled N-acetylcysteine monotherapy in patients with early stage idiopathic pulmonary fibrosis. Respirology (2012) 1.27
Mononuclear copper(II)-superoxo complexes that mimic the structure and reactivity of the active centers of PHM and DbetaM. J Am Chem Soc (2009) 1.27
Synthesis, characterization, and reactivities of manganese(V)-oxo porphyrin complexes. J Am Chem Soc (2007) 1.25
Spectroscopic definition of the ferroxidase site in M ferritin: comparison of binuclear substrate vs cofactor active sites. J Am Chem Soc (2008) 1.24
SOUL in mouse eyes is a new hexameric heme-binding protein with characteristic optical absorption, resonance Raman spectral, and heme-binding properties. Biochemistry (2004) 1.23
A phase II study of S-1 in gemcitabine-refractory metastatic pancreatic cancer. Cancer Chemother Pharmacol (2008) 1.20
A SiPM-based isotropic-3D PET detector X'tal cube with a three-dimensional array of 1 mm(3) crystals. Phys Med Biol (2011) 1.20
Androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin II-induced cardiac fibrosis. J Biol Chem (2005) 1.20
Geometric and electronic structure and reactivity of a mononuclear "side-on" nickel(III)-peroxo complex. Nat Chem (2009) 1.19
Structural and spectroscopic characterization of (mu-hydroxo or mu-oxo)(mu-peroxo)diiron(III) complexes: models for peroxo intermediates of non-heme diiron proteins. J Am Chem Soc (2005) 1.18
Ablation therapy guided by contrast-enhanced sonography with Sonazoid for hepatocellular carcinoma lesions not detected by conventional sonography. J Ultrasound Med (2008) 1.17
Metastatic brain tumors from non-small cell lung cancer with EGFR mutations: distinguishing influence of exon 19 deletion on radiographic features. Lung Cancer (2012) 1.17
VASCULAR-RELATED NAC-DOMAIN6 and VASCULAR-RELATED NAC-DOMAIN7 effectively induce transdifferentiation into xylem vessel elements under control of an induction system. Plant Physiol (2010) 1.16
Primary protein response after ligand photodissociation in carbonmonoxy myoglobin. Proc Natl Acad Sci U S A (2007) 1.14
Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia. Mol Endocrinol (2009) 1.12
Axial ligand substituted nonheme FeIV=O complexes: observation of near-UV LMCT bands and Fe=O Raman vibrations. J Am Chem Soc (2005) 1.11
Current status and evaluation of transnasal esophagogastroduodenoscopy. Dig Endosc (2009) 1.10
Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J Biol Chem (2004) 1.09
Regioselective hydroxylation of the xylyl linker in a diiron(III) complex having a carboxylate-rich ligand with H2O2. Chem Commun (Camb) (2003) 1.09
Detection of the His-heme Fe2+-NO species in the reduction of NO to N2O by ba3-oxidase from thermus thermophilus. J Am Chem Soc (2005) 1.07
Retracted Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF). Proc Natl Acad Sci U S A (2009) 1.06
Roles of the proximal hydrogen bonding network in cytochrome P450cam-catalyzed oxygenation. J Am Chem Soc (2002) 1.06
The ATE genes are responsible for repression of transdifferentiation into xylem cells in Arabidopsis. Plant Physiol (2004) 1.06
Physcomitrella cyclin-dependent kinase A links cell cycle reactivation to other cellular changes during reprogramming of leaf cells. Plant Cell (2011) 1.06
para-Bridged symmetrical pillar[5]arenes: their Lewis acid catalyzed synthesis and host-guest property. J Am Chem Soc (2008) 1.06
The interaction of covalently bound heme with the cytochrome c maturation protein CcmE. J Biol Chem (2004) 1.06
Class III homeodomain leucine-zipper proteins regulate xylem cell differentiation. Plant Cell Physiol (2005) 1.06
The clinical significance of 5% change in vital capacity in patients with idiopathic pulmonary fibrosis: extended analysis of the pirfenidone trial. Respir Res (2011) 1.06
Contribution of NAC transcription factors to plant adaptation to land. Science (2014) 1.06
Investigations of vibrational coherence in the low-frequency region of ferric heme proteins. Biophys J (2007) 1.05
Construction of a square-planar hydroperoxo-copper(II) complex inducing a higher catalytic reactivity. Chem Commun (Camb) (2003) 1.04
A polycomb repressive complex 2 gene regulates apogamy and gives evolutionary insights into early land plant evolution. Proc Natl Acad Sci U S A (2009) 1.04
Structural characterization and remarkable axial ligand effect on the nucleophilic reactivity of a nonheme manganese(III)-peroxo complex. Angew Chem Int Ed Engl (2009) 1.04
Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells. Am J Pathol (2010) 1.04
An inducible RNA interference system in Physcomitrella patens reveals a dominant role of augmin in phragmoplast microtubule generation. Plant Cell (2012) 1.03
Mutations in MYB3R1 and MYB3R4 cause pleiotropic developmental defects and preferential down-regulation of multiple G2/M-specific genes in Arabidopsis. Plant Physiol (2011) 1.03
Moving Iron through ferritin protein nanocages depends on residues throughout each four α-helix bundle subunit. J Biol Chem (2011) 1.03
Estrogens maintain bone mass by regulating expression of genes controlling function and life span in mature osteoclasts. Ann N Y Acad Sci (2009) 1.03
Reactivity of hydroperoxide bound to a mononuclear non-heme iron site. Inorg Chem (2002) 1.02
Coherence spectroscopy investigations of the low-frequency vibrations of heme: effects of protein-specific perturbations. J Am Chem Soc (2008) 1.01
Synthesis, structural, and spectroscopic characterization and reactivities of mononuclear cobalt(III)-peroxo complexes. J Am Chem Soc (2010) 1.01
Ferritins for Chemistry and for Life. Coord Chem Rev (2012) 1.00
Identification of an "end-on" nickel-superoxo adduct, [Ni(tmc)(O2)]+. J Am Chem Soc (2006) 1.00
Crystallographic and spectroscopic studies of peroxide-derived myoglobin compound II and occurrence of protonated FeIV O. J Biol Chem (2007) 1.00
Feasibility and tolerance of 2-way and 4-way angulation videoscopes for unsedated patients undergoing transnasal EGD in GI cancer screening. Gastrointest Endosc (2008) 0.99
The structure of the hyponitrite species in a heme Fe-Cu binuclear center. Angew Chem Int Ed Engl (2007) 0.99
Efficacy of a novel class of RNA interference therapeutic agents. PLoS One (2012) 0.99
Structural characterization of the proximal and distal histidine environment of cytoglobin and neuroglobin. Biochemistry (2005) 0.99
Exploratory analysis of a phase III trial of pirfenidone identifies a subpopulation of patients with idiopathic pulmonary fibrosis as benefiting from treatment. Respir Res (2011) 0.98
Steric and hydrogen-bonding effects on the stability of copper complexes with small molecules. Inorg Chem (2004) 0.98
FT-IR approaches on amyloid fibril structure. Biochim Biophys Acta (2005) 0.98
Structural and Electrochemical Comparison of Copper(II) Complexes with Tripodal Ligands. Inorg Chem (1996) 0.98
CO-dependent activity-controlling mechanism of heme-containing CO-sensor protein, neuronal PAS domain protein 2. J Biol Chem (2005) 0.97
Fluorescent zinc sensor with minimized proton-induced interferences: photophysical mechanism for fluorescence turn-on response and detection of endogenous free zinc ions. Inorg Chem (2012) 0.97
The pituitary function of androgen receptor constitutes a glucocorticoid production circuit. Mol Cell Biol (2007) 0.97
Low frequency spectral density of ferrous heme: perturbations induced by axial ligation and protein insertion. Biophys J (2007) 0.97
[Fe(IV)═O(TBC)(CH3CN)]2+: comparative reactivity of iron(IV)-oxo species with constrained equatorial cyclam ligation. J Am Chem Soc (2012) 0.96
Regioselective arene hydroxylation mediated by a (mu-peroxo)diiron(III) complex: a functional model for toluene monooxygenase. J Am Chem Soc (2007) 0.96