Published in Toxicol Appl Pharmacol on April 08, 2009
Sexually immature male ERE-Luc reporter mice to assess low dose estrogen-like effects of CdCl2 versus dietary Cd. Am J Nucl Med Mol Imaging (2014) 0.75
In vivo imaging of transcriptionally active estrogen receptors. Nat Med (2002) 2.50
International Union of Pharmacology. LXIV. Estrogen receptors. Pharmacol Rev (2006) 2.15
Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J Clin Invest (2010) 1.90
Estrogen receptor-alpha mediates the brain antiinflammatory activity of estradiol. Proc Natl Acad Sci U S A (2003) 1.87
17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization. Mol Cell Biol (2005) 1.80
Silver paper: the future of health promotion and preventive actions, basic research, and clinical aspects of age-related disease--a report of the European Summit on Age-Related Disease. Aging Clin Exp Res (2009) 1.61
Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk. J Biol Chem (2001) 1.60
A lack of ovarian function increases neuroinflammation in aged mice. Endocrinology (2012) 1.53
Regulation of postnatal lung development and homeostasis by estrogen receptor beta. Mol Cell Biol (2003) 1.44
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One (2008) 1.44
Estrogens in the nervous system: mechanisms and nonreproductive functions. Annu Rev Physiol (2004) 1.32
Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor. Biochem Pharmacol (2004) 1.26
Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases. Front Neuroendocrinol (2008) 1.23
The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype. Cancer Res (2005) 1.19
Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proc Natl Acad Sci U S A (2006) 1.17
The endogenous estrogen status regulates microglia reactivity in animal models of neuroinflammation. Endocrinology (2006) 1.13
A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver. Mol Endocrinol (2006) 1.10
Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1. Cell Metab (2011) 1.10
Estrogen action in neuroprotection and brain inflammation. Ann N Y Acad Sci (2006) 0.99
Regulation of the lipopolysaccharide signal transduction pathway by 17beta-estradiol in macrophage cells. J Steroid Biochem Mol Biol (2004) 0.98
Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol. Endocr Relat Cancer (2010) 0.98
HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation. J Mol Endocrinol (2010) 0.98
In vivo imaging reveals selective peroxisome proliferator activated receptor modulator activity of the synthetic ligand 3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid (MK-886). Mol Pharmacol (2008) 0.95
Reporter mice and drug discovery and development. Nat Rev Drug Discov (2005) 0.95
Suppurative adenitis of preputial glands associated with Corynebacterium mastitidis infection in mice. J Am Assoc Lab Anim Sci (2010) 0.92
Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterus. J Steroid Biochem Mol Biol (2005) 0.91
Estrogen receptor-alpha as a drug target candidate for preventing lung inflammation. Endocrinology (2009) 0.89
Transgenic animal models in toxicology: historical perspectives and future outlook. Toxicol Sci (2011) 0.88
Tetradian oscillation of estrogen receptor α is necessary to prevent liver lipid deposition. Proc Natl Acad Sci U S A (2012) 0.86
Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals. Mol Biol Cell (2012) 0.86
Inducible nitric oxide synthase mediates bone loss in ovariectomized mice. Endocrinology (2003) 0.86
Selective agonists of estrogen receptor isoforms: new perspectives for cardiovascular disease. Arterioscler Thromb Vasc Biol (2006) 0.86
Techniques: reporter mice - a new way to look at drug action. Trends Pharmacol Sci (2004) 0.86
Estrogenic activities in rodent estrogen-free diets. Endocrinology (2005) 0.85
Alternative activation of human macrophages is rescued by estrogen treatment in vitro and impaired by menopausal status. J Clin Endocrinol Metab (2015) 0.85
An innovative method to classify SERMs based on the dynamics of estrogen receptor transcriptional activity in living animals. Mol Endocrinol (2010) 0.85
Estrogen receptor antagonist fulvestrant (ICI 182,780) inhibits the anti-inflammatory effect of glucocorticoids. Mol Pharmacol (2006) 0.85
The peroxisome proliferator-activated receptor γ (PPARγ) controls natural protective mechanisms against lipid peroxidation in amyotrophic lateral sclerosis. J Biol Chem (2012) 0.84
Genistein is an efficient estrogen in the whole-body throughout mouse development. Toxicol Sci (2008) 0.83
Identification of xenoestrogens in food additives by an integrated in silico and in vitro approach. Chem Res Toxicol (2009) 0.82
Molecular imaging provides novel insights on estrogen receptor activity in mouse brain. Mol Imaging (2009) 0.82
Novel insights on imaging sex-hormone-dependent tumourigenesis in vivo. Endocr Relat Cancer (2011) 0.81
Estrogen receptor-mediated signalling in female mice is locally activated in response to wounding. Mol Cell Endocrinol (2013) 0.81
European silver paper on the future of health promotion and preventive actions, basic research and clinical aspects of age-related disease. Endokrynol Pol (2009) 0.81
Looking at nuclear receptors from the heights of Erice. Workshop on nuclear receptor structure and function. EMBO Rep (2002) 0.81
The conundrum of estrogen receptor oscillatory activity in the search for an appropriate hormone replacement therapy. Endocrinology (2011) 0.81
Development of a bicistronic vector for multimodality imaging of estrogen receptor activity in a breast cancer model: preliminary application. Eur J Nucl Med Mol Imaging (2007) 0.81
Estrogen receptor alpha, a molecular switch converting transforming growth factor-alpha-mediated proliferation into differentiation in neuroblastoma cells. J Biol Chem (2003) 0.81
Molecular imaging of cytochrome P450 activity in mice. Pharmacol Res (2012) 0.80
Distinct roles of estrogen receptor-alpha and beta in the modulation of vascular inducible nitric-oxide synthase in diabetes. J Pharmacol Exp Ther (2008) 0.79
Cancer modeling: modern imaging applications in the generation of novel animal model systems to study cancer progression and therapy. Int J Biochem Cell Biol (2007) 0.79
Profiling of drug action using reporter mice and molecular imaging. Methods Mol Biol (2010) 0.79
Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPARγ Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen. Environ Health Perspect (2015) 0.78
Novel locally active estrogens accelerate cutaneous wound healing. A preliminary study. Mol Pharm (2009) 0.78
Estrogen-like effects of diet-derived cadmium differ from those of orally administered CdCl(2) in the ERE-luc estrogen reporter mouse model. Toxicol Lett (2010) 0.77
Genistein accumulates in body depots and is mobilized during fasting, reaching estrogenic levels in serum that counter the hormonal actions of estradiol and organochlorines. Toxicol Sci (2007) 0.77
Encompassing receptor flexibility in virtual screening using ensemble docking-based hybrid QSAR: discovery of novel phytochemicals for BACE1 inhibition. Mol Biosyst (2014) 0.76
Molecular imaging, an innovative methodology for whole-body profiling of endocrine disrupter action. Toxicol Sci (2008) 0.76
LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties. J Biol Chem (2014) 0.75
[European Silver Paper. European document on the future of health promotion and preventive measures, basic research and clinical aspects of aging-related diseases]. Rev Esp Geriatr Gerontol (2009) 0.75
Estrogen Receptor-α as a Drug Target Candidate for Preventing Lung Inflammation. Endocr Rev (2009) 0.75
Global profiling of TSEC proliferative potential by the use of a reporter mouse for proliferation. Reprod Sci (2012) 0.75
Reporter mice for the study of long-term effects of drugs and toxic compounds. Methods Mol Biol (2014) 0.75