Published in Biochem Biophys Res Commun on April 14, 2009
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PLoS One (2010) 1.62
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proc Natl Acad Sci U S A (2010) 1.38
Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biol (2010) 1.07
Role of renal DJ-1 in the pathogenesis of hypertension associated with increased reactive oxygen species production. Hypertension (2012) 0.99
Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression. J Biol Chem (2010) 0.94
Cross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for Cancer. Oncoscience (2014) 0.94
SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegeneration. Oxid Med Cell Longev (2013) 0.93
DAMTC regulates cytoskeletal reorganization and cell motility in human lung adenocarcinoma cell line: an integrated proteomics and transcriptomics approach. Cell Death Dis (2012) 0.88
Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease. Cell Signal (2014) 0.86
The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production. Cell Death Differ (2012) 0.83
DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress. PLoS One (2014) 0.78
Preoperative serum 8-hydroxydeoxyguanosine is associated with chemoresistance and is a powerful prognostic factor in endometrioid-type epithelial ovarian cancer. BMC Cancer (2015) 0.75
Epidermal Growth Factor-dependent Activation of the Extracellular Signal-regulated Kinase Pathway by DJ-1 Protein through Its Direct Binding to c-Raf Protein. J Biol Chem (2015) 0.75
NaHS Protects against the Impairments Induced by Oxygen-Glucose Deprivation in Different Ages of Primary Hippocampal Neurons. Front Cell Neurosci (2017) 0.75
Crystallization and preliminary X-ray data analysis of a DJ-1 homologue from Arabidopsis thaliana (AtDJ-1D). Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75
Cytoprotective mechanisms of DJ-1 against oxidative stress through modulating ERK1/2 and ASK1 signal transduction. Redox Biol (2017) 0.75
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell (2013) 24.00
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature (2011) 6.73
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system. Cell Res (2013) 3.50
Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia. Blood (2006) 3.48
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res (2006) 2.81
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes Dev (2012) 2.70
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits. Neuron (2010) 2.53
Shear stress induces endothelial differentiation from a murine embryonic mesenchymal progenitor cell line. Arterioscler Thromb Vasc Biol (2005) 2.51
Randomized open-label phase II study of decitabine in patients with low- or intermediate-risk myelodysplastic syndromes. J Clin Oncol (2013) 2.42
High-efficiency InGaN-based LEDs grown on patterned sapphire substrates. Opt Express (2011) 2.14
Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia. Blood (2008) 2.04
Essential role of microRNA-155 in regulating endothelium-dependent vasorelaxation by targeting endothelial nitric oxide synthase. Hypertension (2012) 1.92
Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Mol Biol Evol (2003) 1.82
The common inhalational anesthetic isoflurane induces apoptosis via activation of inositol 1,4,5-trisphosphate receptors. Anesthesiology (2008) 1.79
Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure (2012) 1.77
Local zones of endoplasmic reticulum complexity confine cargo in neuronal dendrites. Cell (2012) 1.75
Isoflurane preconditioning inhibited isoflurane-induced neurotoxicity. Neurosci Lett (2007) 1.53
[Effects of different statin regimens on lipid profile and serum metalloproteinases in patients with coronary heart disease]. Zhonghua Xin Xue Guan Bing Za Zhi (2009) 1.50
An orthophosphate semiconductor with photooxidation properties under visible-light irradiation. Nat Mater (2010) 1.46
Adipokine resistin promotes in vitro angiogenesis of human endothelial cells. Cardiovasc Res (2006) 1.45
The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation. J Biol Chem (2006) 1.43
HIV prevalence and correlates of unprotected anal intercourse among men who have sex with men, Jinan, China. AIDS Behav (2008) 1.41
Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers. Clin Cancer Res (2008) 1.41
Left atrial dyssynchrony time measured by tissue Doppler imaging to predict atrial fibrillation recurrences after pulmonary vein isolation. Anatol J Cardiol (2014) 1.40
Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation. Cell Res (2012) 1.39
Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics (2010) 1.37
Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia. Leuk Res (2009) 1.37
Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence. Aging (Albany NY) (2010) 1.33
Rising HIV prevalence among married and unmarried among men who have sex with men: Jinan, China. AIDS Behav (2009) 1.32
The association of serotonin transporter genetic polymorphisms and irritable bowel syndrome and its influence on tegaserod treatment in Chinese patients. Dig Dis Sci (2007) 1.32
Phosphorylated α-synuclein in Parkinson's disease. Sci Transl Med (2012) 1.29
Diversity of rotavirus strains among children with acute diarrhea in China: 1998-2000 surveillance study. J Clin Microbiol (2002) 1.29
Genome-wide analysis reveals gene expression and metabolic network dynamics during embryo development in Arabidopsis. Plant Physiol (2011) 1.29
The substantial hospitalization burden of influenza in central China: surveillance for severe, acute respiratory infection, and influenza viruses, 2010-2012. Influenza Other Respir Viruses (2013) 1.28
Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii. Phytochemistry (2007) 1.26
Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana. BMC Genomics (2010) 1.23
Which Chinese men who have sex with men miss out on HIV testing? Sex Transm Infect (2011) 1.22
Pancreatic carcinoma cells express neuropilins and vascular endothelial growth factor, but not vascular endothelial growth factor receptors. Cancer (2004) 1.22
Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor. Blood (2006) 1.22
Bioactive novel polyphenols from the fruit of Manilkara zapota (Sapodilla). J Nat Prod (2003) 1.22
Molecular basis of spectral tuning in the red- and green-sensitive (M/LWS) pigments in vertebrates. Genetics (2008) 1.21
Public perceptions of private health care in socialist China. Health Aff (Millwood) (2004) 1.20
Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation. Circulation (2012) 1.20
Adjuvant gonadotropin-releasing hormone analogues for the prevention of chemotherapy induced premature ovarian failure in premenopausal women. Cochrane Database Syst Rev (2011) 1.18
Modulation of macrophage activation and programming in immunity. J Cell Physiol (2013) 1.17
Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia. Blood (2010) 1.14
Roles of cyclophilins in cancers and other organ systems. World J Surg (2005) 1.14
Stem cells from human-exfoliated deciduous teeth can differentiate into dopaminergic neuron-like cells. Stem Cells Dev (2010) 1.13
Evolutionary dynamics of the interferon-induced transmembrane gene family in vertebrates. PLoS One (2012) 1.13
Intensity-modulated microbend fiber optic sensor for respiratory monitoring and gating during MRI. IEEE Trans Biomed Eng (2013) 1.13
Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20. Mol Immunol (2009) 1.12
Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate. Blood (2010) 1.12
Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry (2006) 1.12
Analysis of polyphenolic antioxidants from the fruits of three pouteria species by selected ion monitoring liquid chromatography-mass spectrometry. J Agric Food Chem (2004) 1.11
Ectodermal Wnt/β-catenin signaling shapes the mouse face. Dev Biol (2010) 1.10
Phase II trial of vorinostat with idarubicin and cytarabine for patients with newly diagnosed acute myelogenous leukemia or myelodysplastic syndrome. J Clin Oncol (2012) 1.10
Oncogenic functions of the transcription factor Nrf2. Free Radic Biol Med (2013) 1.10
An integrated microfluidic array system for evaluating toxicity and teratogenicity of drugs on embryonic zebrafish developmental dynamics. Biomicrofluidics (2011) 1.10
Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells. Cancer Chemother Pharmacol (2008) 1.09
The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy. Clin Cancer Res (2010) 1.08
Viral infection and focal cortical dysplasia. Ann Neurol (2014) 1.08
Quantitative analysis of antiradical phenolic constituents from fourteen edible Myrtaceae fruits. Food Chem (2008) 1.08
Adaptive diversification of vomeronasal receptor 1 genes in rodents. J Mol Evol (2005) 1.07
Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora). J Nat Prod (2006) 1.07
alpha-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity. Neurosci Lett (2009) 1.07
A metal-based inhibitor of tumor necrosis factor-α. Angew Chem Int Ed Engl (2012) 1.06
Effects of 5 HIV protease inhibitors on vasomotor function and superoxide anion production in porcine coronary arteries. J Acquir Immune Defic Syndr (2005) 1.06
Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people. J Gastroenterol Hepatol (2010) 1.05
Semi-quantitative analysis of alpha-synuclein in subcellular pools of rat brain neurons: an immunogold electron microscopic study using a C-terminal specific monoclonal antibody. Brain Res (2008) 1.04
Epigenetics of acute lymphocytic leukemia. Semin Hematol (2009) 1.04
USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription. PLoS Genet (2013) 1.03
Genome-wide association study of meat quality traits in a White Duroc×Erhualian F2 intercross and Chinese Sutai pigs. PLoS One (2013) 1.03
Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response. Int J Cancer (2008) 1.03
Bioactive benzophenones from Garcinia xanthochymus fruits. J Nat Prod (2005) 1.03
Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv. J Proteome Res (2010) 1.02
NaV1.4 mutations cause hypokalaemic periodic paralysis by disrupting IIIS4 movement during recovery. Brain (2014) 1.02
China's evolving health care market: how doctors feel and what they think. Health Policy (2004) 1.02
The activation of HMGB1 as a progression factor on inflammation response in normal human bronchial epithelial cells through RAGE/JNK/NF-κB pathway. Mol Cell Biochem (2013) 1.01
Association of bone morphogenetic protein-2 gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the spine and its severity in Chinese patients. Eur Spine J (2008) 1.00
[Transported fluxes of the riverine carbon and seasonal variation in Pearl River basin]. Huan Jing Ke Xue (2013) 1.00
Controlling assembly of paired gold clusters within apoferritin nanoreactor for in vivo kidney targeting and biomedical imaging. J Am Chem Soc (2011) 1.00
YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation. J Cell Biol (2007) 1.00
A TetR-like regulator broadly affects the expressions of diverse genes in Mycobacterium smegmatis. Nucleic Acids Res (2011) 1.00
A past Haff disease outbreak associated with eating freshwater pomfret in South China. BMC Public Health (2013) 0.99
Roles of neuropilins in neuronal development, angiogenesis, and cancers. World J Surg (2005) 0.98
Genetic alterations in microRNAs in medulloblastomas. Brain Pathol (2011) 0.98
Activation of Erk1/2 and Akt in astrocytes under ischemia. Biochem Biophys Res Commun (2002) 0.98
Differential regulation of CFTRDeltaF508 degradation by ubiquitin ligases gp78 and Hrd1. Int J Biochem Cell Biol (2009) 0.98
Factors affecting the implementation of health legislation and its impact on the rural poor in China: a case study of implementation of the maternal and infant health care law in two poor counties. Int J Health Plann Manage (2004) 0.98
Comparison of the labeling efficiency of BrdU, DiI and FISH labeling techniques in bone marrow stromal cells. Brain Res (2007) 0.97
Role of spinal cord in regulating mouse kidney: a virally mediated trans-synaptic tracing study. Urology (2012) 0.97
Dramatic reduction of liver cancer incidence in young adults: 28 year follow-up of etiological interventions in an endemic area of China. Carcinogenesis (2013) 0.97
α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator. Int J Biochem Cell Biol (2011) 0.96