Jan van Benthem

Author PubWeight™ 29.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hazardous compounds in tobacco smoke. Int J Environ Res Public Health 2011 1.75
2 Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis. Mol Cell Biol 2006 1.63
3 Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010. Arch Toxicol 2011 1.46
4 New and emerging technologies for genetic toxicity testing. Environ Mol Mutagen 2010 1.28
5 How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop. Mutat Res 2007 1.22
6 Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach. Mutat Res 2009 1.17
7 Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop. Mutat Res 2009 0.94
8 Genotoxicity evaluation of amorphous silica nanoparticles of different sizes using the micronucleus and the plasmid lacZ gene mutation assay. Nanotoxicology 2010 0.91
9 lacZ mouse embryonic fibroblasts detect both clastogens and mutagens. Mutat Res 2009 0.89
10 DNA adduct kinetics in reproductive tissues of DNA repair proficient and deficient male mice after oral exposure to benzo(a)pyrene. Environ Mol Mutagen 2010 0.88
11 Evaluation of benzo(a)pyrene-induced gene mutations in male germ cells. Toxicol Sci 2010 0.86
12 ECVAM retrospective validation of in vitro micronucleus test (MNT). Mutagenesis 2008 0.85
13 Inactivation of RAD52 aggravates RAD54 defects in mice but not in Schizosaccharomyces pombe. DNA Repair (Amst) 2005 0.85
14 Can carcinogenic potency be predicted from in vivo genotoxicity data?: a meta-analysis of historical data. Environ Mol Mutagen 2011 0.84
15 p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice. Cancer Res 2004 0.83
16 Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice. Toxicol Appl Pharmacol 2012 0.81
17 Reproductive toxicants have a threshold of adversity. Crit Rev Toxicol 2011 0.81
18 In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop. Mutat Res 2011 0.80
19 A mode-of-action approach for the identification of genotoxic carcinogens. PLoS One 2013 0.80
20 2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair. DNA Repair (Amst) 2005 0.79
21 ECETOC workshop on the biological significance of DNA adducts: summary of follow-up from an expert panel meeting. Mutat Res 2009 0.78
22 New methods for assessing male germ line mutations in humans and genetic risks in their offspring. Mutagenesis 2008 0.78
23 A critical appraisal of the process of regulatory implementation of novel in vivo and in vitro methods for chemical hazard and risk assessment. Crit Rev Toxicol 2014 0.78
24 Evaluation of the Xpa-deficient transgenic mouse model for short-term carcinogenicity testing: 9-month studies with haloperidol, reserpine, phenacetin, and D-mannitol. Toxicol Pathol 2004 0.78
25 Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice. BMC Genomics 2010 0.77
26 DNA-repair-deficient Rad54/Rad54B mice are more sensitive to clastogens than wild-type mice. Toxicol Lett 2008 0.76
27 Follow-up actions from positive results of in vitro genetic toxicity testing. Environ Mol Mutagen 2010 0.76
28 Finding maximal transcriptome differences between reprotoxic and non-reprotoxic phthalate responses in rat testis. J Appl Toxicol 2010 0.76
29 Opportunities to integrate new approaches in genetic toxicology: an ILSI-HESI workshop report. Environ Mol Mutagen 2014 0.76
30 Detecting genotoxic effects of potential clastogens: an in vivo study using the transgenic lacZ plasmid and the MutaMouse model. Mutat Res 2008 0.76
31 Phenacetin acts as a weak genotoxic compound preferentially in the kidney of DNA repair deficient Xpa mice. Mutat Res 2006 0.76
32 Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells. BMC Genomics 2010 0.75
33 Opinion of the Scientific Committee on Consumer Safety (SCCS)--The safety of the use of formaldehyde in nail hardeners. Regul Toxicol Pharmacol 2015 0.75
34 The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development. Environ Mol Mutagen 2013 0.75
35 Is MutaMouse insensitive to clastogens? Mutat Res 2008 0.75
36 Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro. Environ Mol Mutagen 2012 0.75