Published in Hepatology on July 01, 2009
High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology (2010) 4.11
Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition. Am J Physiol Gastrointest Liver Physiol (2011) 1.85
Metabolic syndrome and coronary artery disease in Ossabaw compared with Yucatan swine. Comp Med (2010) 1.61
Shock wave lithotripsy targeting of the kidney and pancreas does not increase the severity of metabolic syndrome in a porcine model. J Urol (2014) 1.47
Exercise training decreases store-operated Ca2+entry associated with metabolic syndrome and coronary atherosclerosis. Cardiovasc Res (2009) 1.43
Bond-selective imaging of deep tissue through the optical window between 1600 and 1850 nm. J Biophotonics (2011) 1.20
Ca2+ regulatory mechanisms of exercise protection against coronary artery disease in metabolic syndrome and diabetes. J Appl Physiol (1985) (2011) 1.14
Morbid obesity and metabolic syndrome in Ossabaw miniature swine are associated with increased platelet reactivity. Diabetes Metab Syndr Obes (2011) 1.09
Characterisation of gut microbiota in Ossabaw and Göttingen minipigs as models of obesity and metabolic syndrome. PLoS One (2013) 1.04
In vitro and in vivo models of non-alcoholic fatty liver disease (NAFLD). Int J Mol Sci (2013) 0.97
Implications of diet on nonalcoholic fatty liver disease. Curr Opin Gastroenterol (2010) 0.96
Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype. J Hepatol (2010) 0.96
A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer. J Hepatol (2016) 0.94
Effect of diet-induced obesity and metabolic syndrome on skeletal muscles of Ossabaw miniature swine. Am J Physiol Endocrinol Metab (2011) 0.93
Animal Models of Nonalcoholic Steatohepatitis: Eat, Delete, and Inflame. Dig Dis Sci (2015) 0.91
Epicardial adipose excision slows the progression of porcine coronary atherosclerosis. J Cardiothorac Surg (2014) 0.90
Biphasic alterations in coronary smooth muscle Ca(2+) regulation in a repeat cross-sectional study of coronary artery disease severity in metabolic syndrome. Atherosclerosis (2016) 0.88
Adipose tissue remodeling in a novel domestic porcine model of diet-induced obesity. Obesity (Silver Spring) (2014) 0.88
Cholesterol-induced non-alcoholic fatty liver disease and atherosclerosis aggravated by systemic inflammation. PLoS One (2014) 0.87
Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. Am J Physiol Gastrointest Liver Physiol (2010) 0.85
Glucan-rich polysaccharides from Pleurotus sajor-caju (Fr.) Singer prevents glucose intolerance, insulin resistance and inflammation in C57BL/6J mice fed a high-fat diet. BMC Complement Altern Med (2012) 0.85
Inflammation in response to n3 fatty acids in a porcine obesity model. Comp Med (2012) 0.84
Transcriptomic analysis of hepatic responses to testosterone deficiency in miniature pigs fed a high-cholesterol diet. BMC Genomics (2015) 0.84
Evaluating the mechanisms of improved glucose homeostasis after bariatric surgery in Ossabaw miniature swine. J Diabetes Res (2014) 0.82
Effects of diet-induced obesity on metabolic parameters and reproductive function in female Ossabaw minipigs. Comp Med (2014) 0.81
Effect of different obesogenic diets on pancreatic histology in Ossabaw miniature swine. Pancreas (2011) 0.80
Hyperinsulinemia shifted energy supply from glucose to ketone bodies in early nonalcoholic steatohepatitis from high-fat high-sucrose diet induced Bama minipigs. Sci Rep (2015) 0.79
Cholesterol induces lipoprotein lipase expression in a tree shrew (Tupaia belangeri chinensis) model of non-alcoholic fatty liver disease. Sci Rep (2015) 0.79
Dietary sugars: their detection by the gut-brain axis and their peripheral and central effects in health and diseases. Eur J Nutr (2014) 0.79
Metabolic syndrome impairs notch signaling and promotes apoptosis in chronically ischemic myocardium. J Thorac Cardiovasc Surg (2014) 0.79
Sustained release nitrite therapy results in myocardial protection in a porcine model of metabolic syndrome with peripheral vascular disease. Am J Physiol Heart Circ Physiol (2015) 0.79
Shock wave lithotripsy does not impair renal function in a Swine model of metabolic syndrome. J Endourol (2014) 0.78
Liver injury and fibrosis induced by dietary challenge in the Ossabaw miniature Swine. PLoS One (2015) 0.77
Effect of renal shock wave lithotripsy on the development of metabolic syndrome in a juvenile swine model: a pilot study. J Urol (2014) 0.77
Farm animal serum proteomics and impact on human health. Int J Mol Sci (2014) 0.77
Challenging the rodent hegemony: a new rabbit model of nonalcoholic steatohepatitis. Am J Pathol (2010) 0.77
Strategies to rescue steatotic livers before transplantation in clinical and experimental studies. World J Gastroenterol (2013) 0.76
Age- and Sex-Associated Effects on Acute-Phase Proteins in Göttingen Minipigs. Comp Med (2015) 0.76
Energy dense, protein restricted diet increases adiposity and perturbs metabolism in young, genetically lean pigs. PLoS One (2013) 0.76
Atorvastatin regulates apoptosis in chronically ischemic myocardium. J Card Surg (2014) 0.76
Comparative Evaluation of Two Venous Sampling Techniques for the Assessment of Pancreatic Insulin and Zinc Release upon Glucose Challenge. J Diabetes Res (2015) 0.75
Tree shrew (Tupaia belangeri chinensis), a novel non-obese animal model of non-alcoholic fatty liver disease. Biol Open (2016) 0.75
Metabolic markers in Ossabaw pigs fed high fat diets enriched in regular or low α-linolenic acid soy oil. Nutr Metab (Lond) (2013) 0.75
Investigating the Metabolic Syndrome: Contributions of Swine Models. Toxicol Pathol (2016) 0.75
Effects of Obesity and Metabolic Syndrome on Steroidogenesis and Folliculogenesis in the Female Ossabaw Mini-Pig. PLoS One (2015) 0.75
Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals. J Transl Med (2015) 0.75
Compensatory Enlargement of Ossabaw Miniature Swine Coronary Arteries in Diffuse Atherosclerosis. Int J Cardiol Heart Vasc (2015) 0.75
Effects of Chronic Consumption of Sugar-Enriched Diets on Brain Metabolism and Insulin Sensitivity in Adult Yucatan Minipigs. PLoS One (2016) 0.75
A Large Animal Survival Model to Evaluate Bariatric Surgery Mechanisms. Surg Sci (2015) 0.75
One What? Why GI Researchers Should Know and Care About the One Health Initiative. Cell Mol Gastroenterol Hepatol (2016) 0.75
Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase. J Diabetes Complications (2017) 0.75
Enhanced colorectal cancer metastases in the alcohol-injured liver. Clin Exp Metastasis (2017) 0.75
Effects of coconut oil on glycemia, inflammation, and urogenital microbial parameters in female Ossabaw mini-pigs. PLoS One (2017) 0.75
Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology (2005) 29.57
Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med (1999) 26.42
Nonalcoholic fatty liver disease. N Engl J Med (2002) 22.41
Steatohepatitis: a tale of two "hits"? Gastroenterology (1998) 13.21
The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol (2003) 8.23
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest (2000) 3.17
Non-alcoholic fatty liver disease: the mist gradually clears. J Hepatol (2008) 3.03
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. J Hepatol (2004) 2.96
Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management. Hepatology (2009) 2.92
Mechanisms of disease progression in nonalcoholic fatty liver disease. Semin Liver Dis (2008) 2.35
Animal models of NASH: getting both pathology and metabolic context right. J Gastroenterol Hepatol (2008) 2.33
Diagnosis and therapy of nonalcoholic steatohepatitis. Gastroenterology (2008) 2.23
Components of metabolic syndrome and coronary artery disease in female Ossabaw swine fed excess atherogenic diet. Comp Med (2006) 2.04
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology (1996) 1.83
Steatohepatitis induced by intragastric overfeeding in mice. Hepatology (2005) 1.73
A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury. Am J Pathol (2006) 1.70
Hepatic triglyceride synthesis and nonalcoholic fatty liver disease. Curr Opin Lipidol (2008) 1.62
Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem (2003) 1.51
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. J Hepatol (2005) 1.40
Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high-fat diet. Hepatol Res (2007) 1.34
Pathology of nonalcoholic steatohepatitis. Hepatol Res (2005) 1.28
Dietary ratio of n-6/n-3 PUFAs and docosahexaenoic acid: actions on bone mineral and serum biomarkers in ovariectomized rats. J Nutr Biochem (2005) 1.23
Feeding apolipoprotein E-knockout mice with cholesterol and fat enriched diets may be a model of non-alcoholic steatohepatitis. Mol Cell Biochem (2005) 1.19
Relationship among histologic, radiologic, and biochemical assessments of hepatic steatosis: a study of human liver samples. J Clin Gastroenterol (2007) 1.18
Soy protein ameliorates metabolic abnormalities in liver and adipose tissue of rats fed a high fat diet. J Nutr (2008) 1.12
Hyperglycemia-induced insulin resistance in diabetic dyslipidemic Yucatan swine. Comp Med (2003) 1.07
Mild hepatic fibrosis in cholesterol and sodium cholate diet-fed rats. J Vet Med Sci (2005) 1.06
Determination of malondialdehyde by liquid chromatography as the 2,4-dinitrophenylhydrazone derivative: a marker for oxidative stress in cell cultures of human hepatoma HepG2. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.91
Hepatic sinusoidal fibrosis induced by cholesterol and stilbestrol in the rabbit: 1. Morphology and inhibition of fibrogenesis by dipyridamole. Hepatology (1996) 0.90
Centrolobular liver fibrosis in the hypercholesterolemic rabbit. Hepatology (1996) 0.88
Impact of dietary protein on lipid metabolism in hamsters is source-dependent and associated with changes in hepatic gene expression. Br J Nutr (2008) 0.87
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med (2010) 13.33
Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr (2005) 6.50
Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct. Drug Saf (2009) 3.48
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. JAMA (2011) 3.37
Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers. Hepatology (2004) 3.00
Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease. Hepatology (2011) 2.97
Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management. Hepatology (2009) 2.92
Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease. Hepatology (2010) 2.86
Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: search for signals. Hepatology (2008) 2.66
Endpoints and clinical trial design for nonalcoholic steatohepatitis. Hepatology (2011) 2.44
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol (2007) 2.37
Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method. Hepatology (2010) 2.30
Initial experience with EUS-guided Tru-cut biopsy of benign liver disease. Gastrointest Endosc (2009) 2.30
Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury. Gastroenterology (2011) 2.25
Smooth muscle cell plasticity: fact or fiction? Circ Res (2012) 2.18
Components of metabolic syndrome and coronary artery disease in female Ossabaw swine fed excess atherogenic diet. Comp Med (2006) 2.04
Label-free bond-selective imaging by listening to vibrationally excited molecules. Phys Rev Lett (2011) 2.01
Crossmatch-positive liver transplantation in patients receiving thymoglobulin-rituximab induction. Transplantation (2014) 2.00
Endoscopic therapy with 2-octyl-cyanoacrylate for the treatment of gastric varices. Dig Dis Sci (2014) 1.99
Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease. Hepatology (2010) 1.91
Impaired function of coronary BK(Ca) channels in metabolic syndrome. Am J Physiol Heart Circ Physiol (2009) 1.89
Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow. Exp Hematol (2002) 1.88
Flipped classroom model improves graduate student performance in cardiovascular, respiratory, and renal physiology. Adv Physiol Educ (2013) 1.88
An assessment of statin safety by hepatologists. Am J Cardiol (2006) 1.78
Unexplained elevations in alanine aminotransferase in individuals with the metabolic syndrome: results from the third National Health and Nutrition Survey (NHANES III). Am J Med Sci (2005) 1.76
Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis. Toxicol Sci (2006) 1.75
Indinavir impairs endothelial function in healthy HIV-negative men. Am Heart J (2005) 1.71
Relationship between hepatitis C and microalbuminuria: results from the NHANES III. Kidney Int (2005) 1.71
Low circulating levels of dehydroepiandrosterone in histologically advanced nonalcoholic fatty liver disease. Hepatology (2008) 1.70
Biliary tract complications after orthotopic liver transplantation with choledochocholedochostomy anastomosis: endoscopic findings and results of therapy. Gastrointest Endosc (2002) 1.70
Lymphangiogenesis does not occur in breast cancer. Am J Surg Pathol (2005) 1.65
Fatty pancreas: a factor in postoperative pancreatic fistula. Ann Surg (2007) 1.62
Metabolic syndrome and coronary artery disease in Ossabaw compared with Yucatan swine. Comp Med (2010) 1.61
HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis. Hepatology (2007) 1.60
Variability in the upper limit of normal for serum alanine aminotransferase levels: a statewide study. Hepatology (2009) 1.59
Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events. Hepatology (2010) 1.58
Lipid-lowering agents that cause drug-induced hepatotoxicity. Clin Liver Dis (2007) 1.56
Label-free molecular imaging of atherosclerotic lesions using multimodal nonlinear optical microscopy. J Biomed Opt (2007) 1.53
Hepatic effects of 2-butoxyethanol in rodents. Toxicol Sci (2002) 1.53
Serum vitamin D concentrations and unexplained elevation in ALT among US adults. Dig Dis Sci (2011) 1.52
Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis. Clin Gastroenterol Hepatol (2004) 1.48
Incidence and predictors of 30-day readmission among patients hospitalized for advanced liver disease. Clin Gastroenterol Hepatol (2010) 1.48
Inverse relationship between long-chain n-3 fatty acids and risk of sudden cardiac death in patients starting hemodialysis. Kidney Int (2013) 1.48
Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr (2015) 1.46
Langerhans' cell histiocytosis involving the pituitary, thyroid, lung, and liver. Endocr Pract (2002) 1.45
Nonalcoholic fatty pancreas disease. HPB (Oxford) (2007) 1.44
Relationship between unexplained elevations in alanine aminotransferase and serum leptin in U.S. adults: results from the Third National Health and Nutrition Examination Survey (NHANES III). J Clin Gastroenterol (2004) 1.43
Exercise training decreases store-operated Ca2+entry associated with metabolic syndrome and coronary atherosclerosis. Cardiovasc Res (2009) 1.43
Imaging and quantitative analysis of atherosclerotic lesions by CARS-based multimodal nonlinear optical microscopy. Arterioscler Thromb Vasc Biol (2009) 1.40
Nonalcoholic fatty liver disease: an emerging threat to obese and diabetic individuals. Ann N Y Acad Sci (2013) 1.40
Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. J Clin Gastroenterol (2011) 1.38
Value of diffusion-weighted MRI for assessing liver fibrosis and cirrhosis. AJR Am J Roentgenol (2009) 1.36
Epicardial perivascular adipose-derived leptin exacerbates coronary endothelial dysfunction in metabolic syndrome via a protein kinase C-beta pathway. Arterioscler Thromb Vasc Biol (2010) 1.35
Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome. Am J Physiol Heart Circ Physiol (2008) 1.32
The impact of videorecording on the quality of colonoscopy performance: a pilot study. Am J Gastroenterol (2010) 1.28
Functional P2Y2 nucleotide receptors mediate uridine 5'-triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries. Circulation (2002) 1.27
Overfed Ossabaw swine with early stage metabolic syndrome have normal coronary collateral development in response to chronic ischemia. Basic Res Cardiol (2012) 1.26
Etiology of new-onset jaundice: how often is it caused by idiosyncratic drug-induced liver injury in the United States? Am J Gastroenterol (2007) 1.24
Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling. Hepatology (2010) 1.23
Perivascular adipose tissue potentiates contraction of coronary vascular smooth muscle: influence of obesity. Circulation (2013) 1.22
Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics (2012) 1.21
Bond-selective imaging of deep tissue through the optical window between 1600 and 1850 nm. J Biophotonics (2011) 1.20
Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network. Hepatology (2014) 1.19
Ectopic expression of IGF-I and Shh by skeletal muscle inhibits disuse-mediated skeletal muscle atrophy and bone osteopenia in vivo. FASEB J (2003) 1.19
Hepatic and extrahepatic cancer in cirrhosis: a longitudinal cohort study. Am J Gastroenterol (2010) 1.19
Marvels, mysteries, and misconceptions of vascular compensation to peripheral artery occlusion. Microcirculation (2010) 1.18
Pancreatic steatosis promotes dissemination and lethality of pancreatic cancer. J Am Coll Surg (2009) 1.18
Relationship among histologic, radiologic, and biochemical assessments of hepatic steatosis: a study of human liver samples. J Clin Gastroenterol (2007) 1.18
Mechanisms of coronary dysfunction in obesity and insulin resistance. Microcirculation (2007) 1.16
Validation of a multivariate model predicting presence and size of varices. J Clin Gastroenterol (2007) 1.15
A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals. Kidney Int (2011) 1.15
Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca(2+). Am J Physiol Endocrinol Metab (2002) 1.14
Is hypothyroidism a risk factor for non-alcoholic steatohepatitis? J Clin Gastroenterol (2003) 1.14
A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis. Hepatology (2011) 1.12
Characteristics of idiosyncratic drug-induced liver injury in children: results from the DILIN prospective study. J Pediatr Gastroenterol Nutr (2011) 1.12
Exercise training prevents Ca2+ dysregulation in coronary smooth muscle from diabetic dyslipidemic yucatan swine. J Appl Physiol (1985) (2006) 1.11
Diversifying Biomedical Training: A Synergistic Intervention. J Women Minor Sci Eng (2010) 1.10
Drug-induced liver injury: a clinical update. Curr Opin Gastroenterol (2010) 1.10
Deep vein thrombosis and pulmonary embolism in cirrhosis patients. Dig Dis Sci (2008) 1.10
Epidemiology of idiosyncratic drug-induced liver injury. Semin Liver Dis (2009) 1.10
Correlation of CT enteroclysis with surgical pathology in Crohn's disease. Am J Gastroenterol (2007) 1.10
Morbid obesity and metabolic syndrome in Ossabaw miniature swine are associated with increased platelet reactivity. Diabetes Metab Syndr Obes (2011) 1.09
Nonalcoholic fatty liver disease in individuals with severe obesity. Clin Liver Dis (2004) 1.09
NAFLD fibrosis score: is it ready for wider use in clinical practice and for clinical trials? Gastroenterology (2013) 1.08
Effects of liver biopsy sample length and number of readings on sampling variability in nonalcoholic Fatty liver disease. Clin Gastroenterol Hepatol (2008) 1.08
Re: Waalkes et al.: Lung tumors in mice induced by "whole-life" inorganic arsenic exposure at human-relevant doses, Arch Toxicol, 2014. Arch Toxicol (2014) 1.08
Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma. Mol Cancer (2010) 1.08
Patients with elevated baseline liver enzymes do not have higher frequency of hepatotoxicity from lovastatin than those with normal baseline liver enzymes. Am J Med Sci (2005) 1.07
Hyperglycemia-induced insulin resistance in diabetic dyslipidemic Yucatan swine. Comp Med (2003) 1.07
Linear low-dose extrapolation for noncancer heath effects is the exception, not the rule. Crit Rev Toxicol (2011) 1.07
Dyslipidemia in patients with nonalcoholic fatty liver disease. Semin Liver Dis (2012) 1.06
Evaluating uncertainty to strengthen epidemiologic data for use in human health risk assessments. Environ Health Perspect (2014) 1.06