Published in Sci Am on May 01, 2009
Cell-laden microengineered gelatin methacrylate hydrogels. Biomaterials (2010) 3.72
Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett (2010) 2.35
Directed 3D cell alignment and elongation in microengineered hydrogels. Biomaterials (2010) 1.94
Electrospun nanofibers for regenerative medicine. Adv Healthc Mater (2011) 1.44
Synthesis and characterization of tunable poly(ethylene glycol): gelatin methacrylate composite hydrogels. Tissue Eng Part A (2011) 1.44
Fiber-based tissue engineering: Progress, challenges, and opportunities. Biotechnol Adv (2012) 1.42
Cell origami: self-folding of three-dimensional cell-laden microstructures driven by cell traction force. PLoS One (2012) 1.34
Sequential assembly of cell-laden hydrogel constructs to engineer vascular-like microchannels. Biotechnol Bioeng (2011) 1.28
Nanocomposite hydrogels for biomedical applications. Biotechnol Bioeng (2013) 1.15
Building vascular networks. Sci Transl Med (2012) 1.14
Hyaluronic Acid-Based Hydrogels: from a Natural Polysaccharide to Complex Networks. Soft Matter (2012) 1.12
Potential feasibility of dental stem cells for regenerative therapies: stem cell transplantation and whole-tooth engineering. Odontology (2011) 1.11
Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels. Acta Biomater (2011) 1.10
The integration of 3-D cell printing and mesoscopic fluorescence molecular tomography of vascular constructs within thick hydrogel scaffolds. Biomaterials (2012) 1.08
Hybrid PGS-PCL microfibrous scaffolds with improved mechanical and biological properties. J Tissue Eng Regen Med (2011) 1.07
Injectable graphene oxide/hydrogel-based angiogenic gene delivery system for vasculogenesis and cardiac repair. ACS Nano (2014) 1.03
Engineered contractile skeletal muscle tissue on a microgrooved methacrylated gelatin substrate. Tissue Eng Part A (2012) 1.03
Directed assembly of cell-laden hydrogels for engineering functional tissues. Organogenesis (2011) 1.03
Exploitation of physical and chemical constraints for three-dimensional microtissue construction in microfluidics. Biomicrofluidics (2011) 1.03
Potential therapeutic applications of muscle-derived mesenchymal stem and progenitor cells. Expert Opin Biol Ther (2010) 1.00
Interface-directed self-assembly of cell-laden microgels. Small (2010) 1.00
Controlling the fibroblastic differentiation of mesenchymal stem cells via the combination of fibrous scaffolds and connective tissue growth factor. Tissue Eng Part A (2011) 0.99
Cell-laden microengineered and mechanically tunable hybrid hydrogels of gelatin and graphene oxide. Adv Mater (2013) 0.97
Creation of bony microenvironment with CaP and cell-derived ECM to enhance human bone-marrow MSC behavior and delivery of BMP-2. Biomaterials (2011) 0.96
Osteoblastic/cementoblastic and neural differentiation of dental stem cells and their applications to tissue engineering and regenerative medicine. Tissue Eng Part B Rev (2012) 0.93
Highly elastomeric poly(glycerol sebacate)-co-poly(ethylene glycol) amphiphilic block copolymers. Biomaterials (2013) 0.92
The expanding world of tissue engineering: the building blocks and new applications of tissue engineered constructs. IEEE Rev Biomed Eng (2012) 0.92
Controlling the spatial organization of cells and extracellular matrix proteins in engineered tissues using ultrasound standing wave fields. Ultrasound Med Biol (2010) 0.91
The osteogenic differentiation of human bone marrow MSCs on HUVEC-derived ECM and β-TCP scaffold. Biomaterials (2012) 0.91
Directed differentiation of size-controlled embryoid bodies towards endothelial and cardiac lineages in RGD-modified poly(ethylene glycol) hydrogels. Adv Healthc Mater (2012) 0.90
Microscale Strategies for Generating Cell-Encapsulating Hydrogels. Polymers (Basel) (2012) 0.90
Microscale technologies and modular approaches for tissue engineering: moving toward the fabrication of complex functional structures. ACS Nano (2011) 0.89
Thermoresponsive Platforms for Tissue Engineering and Regenerative Medicine. AIChE J (2011) 0.89
Endothelial progenitor cells promote directional three-dimensional endothelial network formation by secreting vascular endothelial growth factor. PLoS One (2013) 0.86
Bioengineering: Cellular control in two clicks. Nature (2009) 0.86
Electrical stimulation as a biomimicry tool for regulating muscle cell behavior. Organogenesis (2013) 0.85
Hyperbranched polyester hydrogels with controlled drug release and cell adhesion properties. Biomacromolecules (2013) 0.85
Biomimetic poly(ethylene glycol)-based hydrogels as scaffolds for inducing endothelial adhesion and capillary-like network formation. Biomacromolecules (2012) 0.83
Rational design of nanofiber scaffolds for orthopedic tissue repair and regeneration. Nanomedicine (Lond) (2013) 0.83
Can bone tissue engineering contribute to therapy concepts after resection of musculoskeletal sarcoma? Sarcoma (2013) 0.81
3D Bioprinting for Tissue and Organ Fabrication. Ann Biomed Eng (2016) 0.80
Hydrogels for Engineering of Perfusable Vascular Networks. Int J Mol Sci (2015) 0.80
Advancing Tissue Engineering: A Tale of Nano-, Micro-, and Macroscale Integration. Small (2015) 0.80
Vascularization of three-dimensional collagen hydrogels using ultrasound standing wave fields. Ultrasound Med Biol (2011) 0.80
Monitoring fibrous scaffold guidance of three-dimensional collagen organisation using minimally-invasive second harmonic generation. PLoS One (2014) 0.79
Nanoclay-enriched poly(ɛ-caprolactone) electrospun scaffolds for osteogenic differentiation of human mesenchymal stem cells. Tissue Eng Part A (2014) 0.79
Chemistry and material science at the cell surface. Mater Today (Kidlington) (2010) 0.79
Amphiphilic beads as depots for sustained drug release integrated into fibrillar scaffolds. J Control Release (2014) 0.78
Adult Stem Cell Responses to Nanostimuli. J Funct Biomater (2015) 0.78
Multiscale tissue engineering for liver reconstruction. Organogenesis (2014) 0.78
Repair of sciatic nerve defects using tissue engineered nerves. Neural Regen Res (2013) 0.78
Cell-adhesive and mechanically tunable glucose-based biodegradable hydrogels. Acta Biomater (2010) 0.78
Micro/Nano Multilayered Scaffolds of PLGA and Collagen by Alternately Electrospinning for Bone Tissue Engineering. Nanoscale Res Lett (2016) 0.78
REGENERATIVE ENGINEERING: APPROACHES TO LIMB REGENERATION AND OTHER GRAND CHALLENGES. Regen Eng Transl Med (2015) 0.77
Engineering a biocompatible scaffold with either micrometre or nanometre scale surface topography for promoting protein adsorption and cellular response. Int J Biomater (2013) 0.77
[Mesenchymal stem cells and their interaction with biomaterials: potential applications in tissue engineering]. Pathologe (2011) 0.77
Recent advances of biomaterials in biotherapy. Regen Biomater (2016) 0.76
Cold Water Fish Gelatin Methacryloyl Hydrogel for Tissue Engineering Application. PLoS One (2016) 0.75
Expression of COLLAGEN 1 and ELASTIN Genes in Mitral Valvular Interstitial Cells within Microfiber Reinforced Hydrogel. Cell J (2015) 0.75
Transformation of Breast Reconstruction via Additive Biomanufacturing. Sci Rep (2016) 0.75
Microporous membrane-based liver tissue engineering for the reconstruction of three-dimensional functional liver tissues in vitro. Biomatter (2013) 0.75
Engineering complex tissue-like microgel arrays for evaluating stem cell differentiation. Sci Rep (2016) 0.75
Cell Culture, Technology: Enhancing the Culture of Diagnosing Human Diseases. J Clin Diagn Res (2016) 0.75
Spatial patterning of endothelial cells and vascular network formation using ultrasound standing wave fields. J Acoust Soc Am (2013) 0.75
Graphene-based materials for tissue engineering. Adv Drug Deliv Rev (2016) 0.75
A road map for a tissue engineering concept for restoring structure and function after limb loss. J Mater Sci Mater Med (2013) 0.75
Adaptive responses of murine osteoblasts subjected to coupled mechanical stimuli. J Mech Behav Biomed Mater (2017) 0.75
Anti-fibronectin aptamers improve the colonization of chitosan films modified with D-(+) Raffinose by murine osteoblastic cells. J Mater Sci Mater Med (2017) 0.75
Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol (2007) 17.80
Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov (2009) 12.46
Engineering vascularized skeletal muscle tissue. Nat Biotechnol (2005) 7.73
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci U S A (2006) 6.90
Impact of nanotechnology on drug delivery. ACS Nano (2009) 6.87
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat Biotechnol (2008) 6.81
Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci U S A (2006) 6.66
Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Sci Transl Med (2012) 5.92
Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med (2010) 5.59
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nat Biotechnol (2004) 5.51
Regeneration and experimental orthotopic transplantation of a bioengineered kidney. Nat Med (2013) 5.36
Transdermal drug delivery. Nat Biotechnol (2008) 5.11
Adipose tissue mass can be regulated through the vasculature. Proc Natl Acad Sci U S A (2002) 4.77
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc Natl Acad Sci U S A (2008) 4.57
Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res (2004) 4.56
Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial. Am J Epidemiol (2005) 4.55
Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events. Nat Biotechnol (2008) 4.46
A tough biodegradable elastomer. Nat Biotechnol (2002) 4.35
Lipid-like materials for low-dose, in vivo gene silencing. Proc Natl Acad Sci U S A (2010) 4.25
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proc Natl Acad Sci U S A (2004) 4.13
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials (2006) 4.09
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J Gene Med (2005) 4.04
Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat Mater (2008) 4.00
A reversibly switching surface. Science (2003) 3.97
Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol (2011) 3.95
Small-scale systems for in vivo drug delivery. Nat Biotechnol (2003) 3.90
Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci U S A (2008) 3.80
Nanoparticle delivery of cancer drugs. Annu Rev Med (2011) 3.75
Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 3.66
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles. Proc Natl Acad Sci U S A (2008) 3.62
First-in-human testing of a wirelessly controlled drug delivery microchip. Sci Transl Med (2012) 3.56
Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks. Biomacromolecules (2005) 3.44
Current status and future potential of transdermal drug delivery. Nat Rev Drug Discov (2004) 3.41
Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat Neurosci (2006) 3.35
Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci U S A (2002) 3.35
Treating metastatic cancer with nanotechnology. Nat Rev Cancer (2011) 3.30
Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells. Proc Natl Acad Sci U S A (2007) 3.19
Outbreak of adverse reactions associated with contaminated heparin. N Engl J Med (2008) 3.16
Nanotechnological strategies for engineering complex tissues. Nat Nanotechnol (2010) 3.15
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nat Mater (2010) 3.11
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat Nanotechnol (2012) 3.09
Engineering substrate topography at the micro- and nanoscale to control cell function. Angew Chem Int Ed Engl (2009) 3.09
Microengineered hydrogels for tissue engineering. Biomaterials (2007) 2.87
Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc Natl Acad Sci U S A (2003) 2.86
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. Angew Chem Int Ed Engl (2003) 2.83
The inflammatory responses to silk films in vitro and in vivo. Biomaterials (2005) 2.79
Biodegradable, elastic shape-memory polymers for potential biomedical applications. Science (2002) 2.79
Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform. ACS Nano (2008) 2.76
Nanomedicine: developing smarter therapeutic and diagnostic modalities. Adv Drug Deliv Rev (2006) 2.69
Multi-pulse drug delivery from a resorbable polymeric microchip device. Nat Mater (2003) 2.65
A combinatorial polymer library approach yields insight into nonviral gene delivery. Acc Chem Res (2008) 2.63
A biodegradable and biocompatible gecko-inspired tissue adhesive. Proc Natl Acad Sci U S A (2008) 2.58
Macroporous nanowire nanoelectronic scaffolds for synthetic tissues. Nat Mater (2012) 2.57
Light-induced shape-memory polymers. Nature (2005) 2.52
Risk of cardiovascular disease by hysterectomy status, with and without oophorectomy: the Women's Health Initiative Observational Study. Circulation (2005) 2.49
Medium perfusion enables engineering of compact and contractile cardiac tissue. Am J Physiol Heart Circ Physiol (2003) 2.42
Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett (2007) 2.40
A vector-free microfluidic platform for intracellular delivery. Proc Natl Acad Sci U S A (2013) 2.40
Development of lipidoid-siRNA formulations for systemic delivery to the liver. Mol Ther (2009) 2.39
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem Int Ed Engl (2006) 2.38
Bio-inspired polymer composite actuator and generator driven by water gradients. Science (2013) 2.38
Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett (2010) 2.35
Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip (2007) 2.30
Biocompatibility and biofouling of MEMS drug delivery devices. Biomaterials (2003) 2.27
Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow. Ann Biomed Eng (2004) 2.26
Endothelialized microvasculature based on a biodegradable elastomer. Tissue Eng (2005) 2.23
Silk implants for the healing of critical size bone defects. Bone (2005) 2.22
PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery. Biomaterials (2008) 2.21
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci U S A (2010) 2.21
Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds. Tissue Eng (2006) 2.20
Micromolding of shape-controlled, harvestable cell-laden hydrogels. Biomaterials (2006) 2.12
Nanostructured materials for applications in drug delivery and tissue engineering. J Biomater Sci Polym Ed (2007) 2.12
Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo. Circ Res (2007) 2.12
In vivo engineering of organs: the bone bioreactor. Proc Natl Acad Sci U S A (2005) 2.04
Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines. Nat Mater (2004) 2.03
Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proc Natl Acad Sci U S A (2004) 2.03
Oxygen gradients correlate with cell density and cell viability in engineered cardiac tissue. Biotechnol Bioeng (2006) 2.01
In vivo degradation characteristics of poly(glycerol sebacate). J Biomed Mater Res A (2003) 2.01
Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane). Biomed Microdevices (2004) 1.97
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling. Nat Biotechnol (2013) 1.97
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds. J Biomed Mater Res A (2004) 1.94
Biocompatibility analysis of poly(glycerol sebacate) as a nerve guide material. Biomaterials (2005) 1.93
Measurement and predictors of resilience among community-dwelling older women. J Psychiatr Res (2008) 1.91
Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab Chip (2005) 1.89
Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters). Mol Ther (2005) 1.87
Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery. Bioconjug Chem (2003) 1.87
Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery. Nano Lett (2009) 1.86
Quantitative and comparative studies of the vocal fold extracellular matrix II: collagen. Ann Otol Rhinol Laryngol (2006) 1.85
A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning. Biomaterials (2004) 1.84
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles. Proc Natl Acad Sci U S A (2009) 1.83
New opportunities: the use of nanotechnologies to manipulate and track stem cells. Cell Stem Cell (2008) 1.82
Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. J Am Chem Soc (2003) 1.81
Microfluidic platform for controlled synthesis of polymeric nanoparticles. Nano Lett (2008) 1.80
A polymer library approach to suicide gene therapy for cancer. Proc Natl Acad Sci U S A (2004) 1.79
Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates. Biomaterials (2006) 1.79
Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction. Biomaterials (2005) 1.78
Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics. Biomaterials (2005) 1.78
High-density seeding of myocyte cells for cardiac tissue engineering. Biotechnol Bioeng (2003) 1.77