Published in J Org Chem on June 19, 2009
Enantioselective synthesis of allylboronates bearing a tertiary or quaternary B-substituted stereogenic carbon by NHC-Cu-catalyzed substitution reactions. J Am Chem Soc (2010) 1.44
Enantioselective synthesis of homoallylic amines through reactions of (pinacolato)allylborons with aryl-, heteroaryl-, alkyl-, or alkene-substituted aldimines catalyzed by chiral C1-symmetric NHC-Cu complexes. J Am Chem Soc (2011) 1.21
Enantioselective synthesis of boron-substituted quaternary carbons by NHC-Cu-catalyzed boronate conjugate additions to unsaturated carboxylic esters, ketones, or thioesters. J Am Chem Soc (2010) 1.20
Enantioselective conjugate silyl additions to cyclic and acyclic unsaturated carbonyls catalyzed by Cu complexes of chiral N-heterocyclic carbenes. J Am Chem Soc (2010) 1.16
Stereoisomerically pure trisubstituted vinylaluminum reagents and their utility in copper-catalyzed enantioselective synthesis of 1,4-dienes containing Z or E alkenes. Angew Chem Int Ed Engl (2010) 1.05
Quaternary carbon stereogenic centers through copper-catalyzed enantioselective allylic substitutions with readily accessible aryl- or heteroaryllithium reagents and aluminum chlorides. Angew Chem Int Ed Engl (2010) 1.00
Multifunctional organoboron compounds for scalable natural product synthesis. Nature (2014) 1.00
Synthesis of quaternary carbon stereogenic centers through enantioselective Cu-catalyzed allylic substitutions with vinylaluminum reagents. J Am Chem Soc (2010) 0.99
A robust, efficient, and highly enantioselective method for synthesis of homopropargyl amines. Angew Chem Int Ed Engl (2012) 0.99
Metal-free catalytic enantioselective C-B bond formation: (pinacolato)boron conjugate additions to α,β-unsaturated ketones, esters, Weinreb amides, and aldehydes promoted by chiral N-heterocyclic carbenes. J Am Chem Soc (2012) 0.96
Modular monodentate oxaphospholane ligands: utility in highly efficient and enantioselective 1,4-diboration of 1,3-dienes. Angew Chem Int Ed Engl (2011) 0.93
A broadly applicable NHC-Cu-catalyzed approach for efficient, site-, and enantioselective coupling of readily accessible (pinacolato)alkenylboron compounds to allylic phosphates and applications to natural product synthesis. J Am Chem Soc (2014) 0.86
NHC-Cu-Catalyzed Silyl Conjugate Additions to Acyclic and Cyclic Dienones and Dienoates. Efficient Site-, Diastereo- and Enantioselective Synthesis of Carbonyl-Containing Allylsilanes. Organometallics (2012) 0.79
Enantioselective synthesis of boron-substituted quaternary carbon stereogenic centers through NHC-catalyzed conjugate additions of (pinacolato)boron units to enones. Angew Chem Int Ed Engl (2014) 0.79
Palladium-catalyzed Hiyama cross-coupling of aryltrifluorosilanes with aryl and heteroaryl chlorides. J Org Chem (2011) 0.78
Molybdenum and tungsten imido alkylidene complexes as efficient olefin-metathesis catalysts. Angew Chem Int Ed Engl (2003) 4.01
Highly efficient molybdenum-based catalysts for enantioselective alkene metathesis. Nature (2008) 3.36
Catalytic Z-selective olefin cross-metathesis for natural product synthesis. Nature (2011) 2.89
Highly Z- and enantioselective ring-opening/cross-metathesis reactions catalyzed by stereogenic-at-Mo adamantylimido complexes. J Am Chem Soc (2009) 2.17
Enantioselective silyl protection of alcohols catalysed by an amino-acid-based small molecule. Nature (2006) 2.16
Highly Z-selective metathesis homocoupling of terminal olefins. J Am Chem Soc (2009) 2.01
Dipyrrolyl precursors to bisalkoxide molybdenum olefin metathesis catalysts. J Am Chem Soc (2006) 1.94
Z-selective olefin metathesis processes catalyzed by a molybdenum hexaisopropylterphenoxide monopyrrolide complex. J Am Chem Soc (2009) 1.83
A readily available chiral Ag-based N-heterocyclic carbene complex for use in efficient and highly enantioselective Ru-catalyzed olefin metathesis and Cu-catalyzed allylic alkylation reactions. J Am Chem Soc (2005) 1.78
Design and stereoselective preparation of a new class of chiral olefin metathesis catalysts and application to enantioselective synthesis of quebrachamine: catalyst development inspired by natural product synthesis. J Am Chem Soc (2009) 1.77
All-carbon quaternary stereogenic centers by enantioselective cu-catalyzed conjugate additions promoted by a chiral N-heterocyclic carbene. Angew Chem Int Ed Engl (2007) 1.76
Efficient boron-copper additions to aryl-substituted alkenes promoted by NHC-based catalysts. enantioselective Cu-catalyzed hydroboration reactions. J Am Chem Soc (2009) 1.74
Synthesis of monoalkoxide monopyrrolyl complexes Mo(NR)(CHR')(OR'')(pyrrolyl): enyne metathesis with high oxidation state catalysts. J Am Chem Soc (2007) 1.63
Chiral Ru-based complexes for asymmetric olefin metathesis: enhancement of catalyst activity through steric and electronic modifications. J Am Chem Soc (2003) 1.60
Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring beta-substituted cyclic enones. Angew Chem Int Ed Engl (2008) 1.59
Vicinal diboronates in high enantiomeric purity through tandem site-selective NHC-Cu-catalyzed boron-copper additions to terminal alkynes. J Am Chem Soc (2009) 1.51
Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis. Nature (2011) 1.50
Highly site- and enantioselective Cu-catalyzed allylic alkylation reactions with easily accessible vinylaluminum reagents. J Am Chem Soc (2007) 1.48
Enantioselective synthesis of allylboronates bearing a tertiary or quaternary B-substituted stereogenic carbon by NHC-Cu-catalyzed substitution reactions. J Am Chem Soc (2010) 1.44
Cu-catalyzed asymmetric allylic alkylations of aromatic and aliphatic phosphates with alkylzinc reagents. An effective method for enantioselective synthesis of tertiary and quaternary carbons. J Am Chem Soc (2004) 1.44
Chiral N-heterocyclic carbenes in natural product synthesis: application of Ru-catalyzed asymmetric ring-opening/cross-metathesis and Cu-catalyzed allylic alkylation to total synthesis of baconipyrone C. Angew Chem Int Ed Engl (2007) 1.43
Enantioselective synthesis of cyclic amides and amines through mo-catalyzed asymmetric ring-closing metathesis. J Am Chem Soc (2005) 1.42
A practical method for enantioselective synthesis of all-carbon quaternary stereogenic centers through NHC-Cu-catalyzed conjugate additions of alkyl- and arylzinc reagents to beta-substituted cyclic enones. J Am Chem Soc (2006) 1.40
The significance of degenerate processes to enantioselective olefin metathesis reactions promoted by stereogenic-at-Mo complexes. J Am Chem Soc (2009) 1.37
Simple organic molecules as catalysts for enantioselective synthesis of amines and alcohols. Nature (2013) 1.34
Site- and enantioselective formation of allene-bearing tertiary or quaternary carbon stereogenic centers through NHC-Cu-catalyzed allylic substitution. J Am Chem Soc (2012) 1.33
Enantioselective total synthesis of clavirolide C. Applications of Cu-catalyzed asymmetric conjugate additions and Ru-catalyzed ring-closing metathesis. J Am Chem Soc (2008) 1.33
Efficient enantioselective synthesis of functionalized tetrahydropyrans by Ru-catalyzed asymmetric ring-opening metathesis/cross-metathesis (AROM/CM). J Am Chem Soc (2004) 1.32
Comparison of Ru- and Mo-based chiral olefin metathesis catalysts. Complementarity in asymmetric ring-opening/cross-metathesis reactions of oxa- and azabicycles. Org Lett (2007) 1.32
Bidentate NHC-based chiral ligands for efficient Cu-catalyzed enantioselective allylic alkylations: structure and activity of an air-stable chiral Cu complex. J Am Chem Soc (2004) 1.32
Efficient and practical Ag-catalyzed cycloadditions between arylimines and the Danishefsky diene. J Am Chem Soc (2003) 1.30
Inversion of configuration at the metal in diastereomeric imido alkylidene monoaryloxide monopyrrolide complexes of molybdenum. J Am Chem Soc (2009) 1.26
Enol ethers as substrates for efficient Z- and enantioselective ring-opening/cross-metathesis reactions promoted by stereogenic-at-Mo complexes: utility in chemical synthesis and mechanistic attributes. J Am Chem Soc (2012) 1.23
Room Temperature Z-Selective Homocoupling of α Olefins by Tungsten Catalysts. Organometallics (2011) 1.22
Enantioselective synthesis of medium-ring heterocycles, tertiary ethers, and tertiary alcohols by Mo-catalyzed ring-closing metathesis. J Am Chem Soc (2002) 1.22
Alpha-selective Ni-catalyzed hydroalumination of aryl- and alkyl-substituted terminal alkynes: practical syntheses of internal vinyl aluminums, halides, or boronates. J Am Chem Soc (2010) 1.22
Synthesis of Z-(pinacolato)allylboron and Z-(pinacolato)alkenylboron compounds through stereoselective catalytic cross-metathesis. J Am Chem Soc (2013) 1.21
Alkylidene and metalacyclic complexes of tungsten that contain a chiral biphenoxide ligand. synthesis, asymmetric ring-closing metathesis, and mechanistic investigations. J Am Chem Soc (2003) 1.21
Endo-selective enyne ring-closing metathesis promoted by stereogenic-at-Mo monoalkoxide and monoaryloxide complexes. Efficient synthesis of cyclic dienes not accessible through reactions with Ru carbenes. J Am Chem Soc (2009) 1.21
Diphenylamido Precursors to Bisalkoxide Molybdenum Olefin Metathesis Catalysts. Organometallics (2006) 1.21
Enantioselective synthesis of homoallylic amines through reactions of (pinacolato)allylborons with aryl-, heteroaryl-, alkyl-, or alkene-substituted aldimines catalyzed by chiral C1-symmetric NHC-Cu complexes. J Am Chem Soc (2011) 1.21
Enantioselective synthesis of boron-substituted quaternary carbons by NHC-Cu-catalyzed boronate conjugate additions to unsaturated carboxylic esters, ketones, or thioesters. J Am Chem Soc (2010) 1.20
Isolation of pure disubstituted E olefins through Mo-catalyzed Z-selective ethenolysis of stereoisomeric mixtures. J Am Chem Soc (2011) 1.20
Kinetic resolution of 1,2-diols through highly site- and enantioselective catalytic silylation. Angew Chem Int Ed Engl (2007) 1.19
Enhancement of enantioselectivity by THF in asymmetric mo-catalyzed olefin metathesis. Catalytic enantioselective synthesis of cyclic tertiary ethers and spirocycles. J Am Chem Soc (2002) 1.17
A recyclable chiral Ru catalyst for enantioselective olefin metathesis. Efficient catalytic asymmetric ring-opening/cross metathesis in air. J Am Chem Soc (2002) 1.16
Enantioselective conjugate silyl additions to cyclic and acyclic unsaturated carbonyls catalyzed by Cu complexes of chiral N-heterocyclic carbenes. J Am Chem Soc (2010) 1.16
Highly selective methods for synthesis of internal (α-) vinylboronates through efficient NHC-Cu-catalyzed hydroboration of terminal alkynes. Utility in chemical synthesis and mechanistic basis for selectivity. J Am Chem Soc (2011) 1.16
Stereogenic-at-metal Zn- and Al-based N-heterocyclic carbene (NHC) complexes as bifunctional catalysts in Cu-free enantioselective allylic alkylations. J Am Chem Soc (2009) 1.15
Cu-catalyzed chemoselective preparation of 2-(pinacolato)boron-substituted allylcopper complexes and their in situ site-, diastereo-, and enantioselective additions to aldehydes and ketones. Angew Chem Int Ed Engl (2013) 1.15
Enantioselective synthesis of nitroalkanes bearing all-carbon quaternary stereogenic centers through Cu-catalyzed asymmetric conjugate additions. J Am Chem Soc (2005) 1.14
Total synthesis of anti-HIV agent chloropeptin I. J Am Chem Soc (2003) 1.11
Efficient catalytic enantioselective synthesis of unsaturated amines: preparation of small- and medium-ring cyclic amines through mo-catalyzed asymmetric ring-closing metathesis in the absence of solvent. J Am Chem Soc (2002) 1.10
Lewis base activation of grignard reagents with N-heterocyclic carbenes. Cu-free catalytic enantioselective additions to gamma-chloro-alpha,beta-unsaturated esters. J Am Chem Soc (2006) 1.10
Ethenolysis reactions catalyzed by imido alkylidene monoaryloxide monopyrrolide (MAP) complexes of molybdenum. J Am Chem Soc (2009) 1.09
Catalytic enantioselective alkylations of tetrasubstituted olefins. Synthesis of all-carbon quaternary stereogenic centers through Cu-catalyzed asymmetric conjugate additions of alkylzinc reagents to enones. J Am Chem Soc (2005) 1.09
NHC-Cu-catalyzed protoboration of monosubstituted allenes. Ligand-controlled site selectivity, application to synthesis and mechanism. Org Lett (2013) 1.08
Enantioselective synthesis of allylsilanes bearing tertiary and quaternary Si-substituted carbons through Cu-catalyzed allylic alkylations with alkylzinc and arylzinc reagents. Angew Chem Int Ed Engl (2007) 1.06
Stereoisomerically pure trisubstituted vinylaluminum reagents and their utility in copper-catalyzed enantioselective synthesis of 1,4-dienes containing Z or E alkenes. Angew Chem Int Ed Engl (2010) 1.05
Z-Selective olefin metathesis reactions promoted by tungsten oxo alkylidene complexes. J Am Chem Soc (2011) 1.04
Catalytic enantioselective silylation of acyclic and cyclic triols: application to total syntheses of cleroindicins D, F, and C. Angew Chem Int Ed Engl (2009) 1.04
Catalytic homologation of vinyltributylstannane to allyltributylstannane by Mo(IV) complexes in the presence of ethylene. J Am Chem Soc (2004) 1.03
Z-selective metathesis homocoupling of 1,3-dienes by molybdenum and tungsten monoaryloxide pyrrolide (MAP) complexes. J Am Chem Soc (2012) 1.00
Quaternary carbon stereogenic centers through copper-catalyzed enantioselective allylic substitutions with readily accessible aryl- or heteroaryllithium reagents and aluminum chlorides. Angew Chem Int Ed Engl (2010) 1.00
Regiodivergent reactions through catalytic enantioselective silylation of chiral diols. Synthesis of sapinofuranone A. Org Lett (2011) 0.99
Synthesis of quaternary carbon stereogenic centers through enantioselective Cu-catalyzed allylic substitutions with vinylaluminum reagents. J Am Chem Soc (2010) 0.99
Enantioselective synthesis of cyclic secondary amines through Mo-catalyzed asymmetric ring-closing metathesis (ARCM). Org Lett (2003) 0.99
Highly enantioselective Cu-catalyzed conjugate additions of dialkylzinc reagents to unsaturated furanones and pyranones: preparation of air-stable and catalytically active Cu-peptide complexes. Angew Chem Int Ed Engl (2005) 0.99
A robust, efficient, and highly enantioselective method for synthesis of homopropargyl amines. Angew Chem Int Ed Engl (2012) 0.99
An enantiomerically pure adamantylimido molybdenum alkylidene complex. An effective new catalyst for enantioselective olefin metathesis. J Am Chem Soc (2003) 0.98
Z- and enantioselective ring-opening/cross-metathesis with enol ethers catalyzed by stereogenic-at-Ru carbenes: reactivity, selectivity, and Curtin-Hammett kinetics. J Am Chem Soc (2012) 0.98
NHC-Cu-catalyzed enantioselective hydroboration of acyclic and exocyclic 1,1-disubstituted aryl alkenes. Angew Chem Int Ed Engl (2011) 0.97
Catalytic Z-selective cross-metathesis with secondary silyl- and benzyl-protected allylic ethers: mechanistic aspects and applications to natural product synthesis. Angew Chem Int Ed Engl (2013) 0.96
Enantioselective synthesis of alkyne-substituted quaternary carbon stereogenic centers through NHC-Cu-catalyzed allylic substitution reactions with (i-Bu)2(alkynyl)aluminum reagents. J Am Chem Soc (2011) 0.96
Metal-free catalytic enantioselective C-B bond formation: (pinacolato)boron conjugate additions to α,β-unsaturated ketones, esters, Weinreb amides, and aldehydes promoted by chiral N-heterocyclic carbenes. J Am Chem Soc (2012) 0.96
Directed catalytic asymmetric olefin metathesis. Selectivity control by enoate and ynoate groups in Ru-catalyzed asymmetric ring-opening/cross-metathesis. J Am Chem Soc (2007) 0.95
Copper-catalyzed enantioselective allylic substitution with readily accessible carbonyl- and acetal-containing vinylboron reagents. Angew Chem Int Ed Engl (2012) 0.95
Enantioselective total synthesis of erogorgiaene: applications of asymmetric Cu-catalyzed conjugate additions of alkylzincs to acyclic enones. J Am Chem Soc (2004) 0.95
Readily accessible and easily modifiable Ru-based catalysts for efficient and Z-selective ring-opening metathesis polymerization and ring-opening/cross-metathesis. J Am Chem Soc (2013) 0.93
Broadly applicable Z- and diastereoselective ring-opening/cross-metathesis catalyzed by a dithiolate ru complex. Angew Chem Int Ed Engl (2014) 0.92
Mo-catalyzed asymmetric olefin metathesis in target-oriented synthesis: enantioselective synthesis of (+)-africanol. Proc Natl Acad Sci U S A (2004) 0.92
Molybdenum-based complexes with two aryloxides and a pentafluoroimido ligand: catalysts for efficient Z-selective synthesis of a macrocyclic trisubstituted alkene by ring-closing metathesis. Angew Chem Int Ed Engl (2013) 0.92
Formation of vinyl-, vinylhalide- or acyl-substituted quaternary carbon stereogenic centers through NHC-Cu-catalyzed enantioselective conjugate additions of Si-containing vinylaluminums to β-substituted cyclic enones. J Am Chem Soc (2010) 0.91
A highly efficient and practical method for catalytic asymmetric vinylogous Mannich (AVM) reactions. Angew Chem Int Ed Engl (2006) 0.91
Enantioselective synthesis of cyclic enol ethers and all-carbon quaternary stereogenic centers through catalytic asymmetric ring-closing metathesis. J Am Chem Soc (2006) 0.91
Diastereo- and enantioselective reactions of bis(pinacolato)diboron, 1,3-enynes, and aldehydes catalyzed by an easily accessible bisphosphine-Cu complex. J Am Chem Soc (2014) 0.90
Metal-free catalytic C-Si bond formation in an aqueous medium. Enantioselective NHC-catalyzed silyl conjugate additions to cyclic and acyclic α,β-unsaturated carbonyls. J Am Chem Soc (2011) 0.90
Ag-catalyzed diastereo- and enantioselective vinylogous Mannich reactions of alpha-ketoimine esters. Development of a method and investigation of its mechanism. J Am Chem Soc (2009) 0.90
Supported chiral Mo-based complexes as efficient catalysts for enantioselective olefin metathesis. J Am Chem Soc (2004) 0.90
Synthesis of (±)-tetrapetalone A-Me aglycon. Angew Chem Int Ed Engl (2014) 0.90
Catalytic enantioselective protoboration of disubstituted allenes. Access to alkenylboron compounds in high enantiomeric purity. Org Lett (2014) 0.89
Catalytic Z-selective cross-metathesis in complex molecule synthesis: a convergent stereoselective route to disorazole C1. J Am Chem Soc (2014) 0.89
Synthesis of High Oxidation State Molybdenum Imido Heteroatom-Substituted Alkylidene Complexes. Organometallics (2013) 0.89
Aluminum-catalyzed asymmetric alkylations of pyridyl-substituted alkynyl ketones with dialkylzinc reagents. J Am Chem Soc (2008) 0.88
A chiral Ag-based catalyst for practical, efficient, and highly enantioselective additions of enolsilanes to alpha-ketoesters. J Am Chem Soc (2006) 0.88