Published in J Am Chem Soc on August 19, 2009
Vicinal diboronates in high enantiomeric purity through tandem site-selective NHC-Cu-catalyzed boron-copper additions to terminal alkynes. J Am Chem Soc (2009) 1.51
Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to gamma-lactams. Nat Chem (2010) 1.44
Enantioselective construction of all-carbon quaternary centers by branch-selective Pd-catalyzed allyl-allyl cross-coupling. J Am Chem Soc (2011) 1.34
Site- and enantioselective formation of allene-bearing tertiary or quaternary carbon stereogenic centers through NHC-Cu-catalyzed allylic substitution. J Am Chem Soc (2012) 1.33
Enantioselective synthesis of homoallylic amines through reactions of (pinacolato)allylborons with aryl-, heteroaryl-, alkyl-, or alkene-substituted aldimines catalyzed by chiral C1-symmetric NHC-Cu complexes. J Am Chem Soc (2011) 1.21
Stereoisomerically pure trisubstituted vinylaluminum reagents and their utility in copper-catalyzed enantioselective synthesis of 1,4-dienes containing Z or E alkenes. Angew Chem Int Ed Engl (2010) 1.05
Quaternary carbon stereogenic centers through copper-catalyzed enantioselective allylic substitutions with readily accessible aryl- or heteroaryllithium reagents and aluminum chlorides. Angew Chem Int Ed Engl (2010) 1.00
Synthesis of quaternary carbon stereogenic centers through enantioselective Cu-catalyzed allylic substitutions with vinylaluminum reagents. J Am Chem Soc (2010) 0.99
Enantioselective synthesis of alkyne-substituted quaternary carbon stereogenic centers through NHC-Cu-catalyzed allylic substitution reactions with (i-Bu)2(alkynyl)aluminum reagents. J Am Chem Soc (2011) 0.96
Formation of vinyl-, vinylhalide- or acyl-substituted quaternary carbon stereogenic centers through NHC-Cu-catalyzed enantioselective conjugate additions of Si-containing vinylaluminums to β-substituted cyclic enones. J Am Chem Soc (2010) 0.91
A broadly applicable NHC-Cu-catalyzed approach for efficient, site-, and enantioselective coupling of readily accessible (pinacolato)alkenylboron compounds to allylic phosphates and applications to natural product synthesis. J Am Chem Soc (2014) 0.86
Catalytic SN 2'- and Enantioselective Allylic Substitution with a Diborylmethane Reagent and Application in Synthesis. Angew Chem Int Ed Engl (2016) 0.84
Enantioselective CuH-Catalyzed Hydroallylation of Vinylarenes. J Am Chem Soc (2016) 0.81
Enantioselective Palladium-Catalyzed Alkenylation of Trisubstituted Alkenols To Form Allylic Quaternary Centers. J Am Chem Soc (2016) 0.77
Highly efficient molybdenum-based catalysts for enantioselective alkene metathesis. Nature (2008) 3.36
Lewis base catalysis in organic synthesis. Angew Chem Int Ed Engl (2008) 2.76
Palladium complexes of N-heterocyclic carbenes as catalysts for cross-coupling reactions--a synthetic chemist's perspective. Angew Chem Int Ed Engl (2007) 2.11
A readily available chiral Ag-based N-heterocyclic carbene complex for use in efficient and highly enantioselective Ru-catalyzed olefin metathesis and Cu-catalyzed allylic alkylation reactions. J Am Chem Soc (2005) 1.78
All-carbon quaternary stereogenic centers by enantioselective cu-catalyzed conjugate additions promoted by a chiral N-heterocyclic carbene. Angew Chem Int Ed Engl (2007) 1.76
Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring beta-substituted cyclic enones. Angew Chem Int Ed Engl (2008) 1.59
Highly site- and enantioselective Cu-catalyzed allylic alkylation reactions with easily accessible vinylaluminum reagents. J Am Chem Soc (2007) 1.48
Cu-catalyzed asymmetric allylic alkylations of aromatic and aliphatic phosphates with alkylzinc reagents. An effective method for enantioselective synthesis of tertiary and quaternary carbons. J Am Chem Soc (2004) 1.44
Chiral N-heterocyclic carbenes in natural product synthesis: application of Ru-catalyzed asymmetric ring-opening/cross-metathesis and Cu-catalyzed allylic alkylation to total synthesis of baconipyrone C. Angew Chem Int Ed Engl (2007) 1.43
A practical method for enantioselective synthesis of all-carbon quaternary stereogenic centers through NHC-Cu-catalyzed conjugate additions of alkyl- and arylzinc reagents to beta-substituted cyclic enones. J Am Chem Soc (2006) 1.40
Enantioselective total synthesis of clavirolide C. Applications of Cu-catalyzed asymmetric conjugate additions and Ru-catalyzed ring-closing metathesis. J Am Chem Soc (2008) 1.33
Bidentate NHC-based chiral ligands for efficient Cu-catalyzed enantioselective allylic alkylations: structure and activity of an air-stable chiral Cu complex. J Am Chem Soc (2004) 1.32
Small peptides as ligands for catalytic asymmetric alkylations of olefins. Rational design of catalysts or of searches that lead to them? Chem Commun (Camb) (2004) 1.29
Recent progress in asymmetric allylic substitutions catalyzed by chiral copper complexes. Angew Chem Int Ed Engl (2005) 1.28
Copper-catalyzed asymmetric conjugate addition of Grignard reagents to trisubstituted enones. Construction of all-carbon quaternary chiral centers. J Am Chem Soc (2006) 1.26
Towards perfect catalytic asymmetric synthesis: dual activation of the electrophile and the nucleophile. Angew Chem Int Ed Engl (2004) 1.18
Bifunctional asymmetric catalysis: cooperative Lewis acid/base systems. Acc Chem Res (2008) 1.13
Lewis base activation of grignard reagents with N-heterocyclic carbenes. Cu-free catalytic enantioselective additions to gamma-chloro-alpha,beta-unsaturated esters. J Am Chem Soc (2006) 1.10
Enantioselective synthesis of allylsilanes bearing tertiary and quaternary Si-substituted carbons through Cu-catalyzed allylic alkylations with alkylzinc and arylzinc reagents. Angew Chem Int Ed Engl (2007) 1.06
Activation of organozinc reagents with t-Bu-P4 base for transition metal-free catalytic SN2' reaction. Chem Commun (Camb) (2008) 1.03
Asymmetric conjugate addition of organozinc compounds to alpha,beta-unsaturated aldehydes and ketones with [2.2]paracyclophaneketimine ligands without added copper salts. Angew Chem Int Ed Engl (2005) 0.97
Asymmetric lithium(I) and copper(II) alkoxy-N-heterocyclic carbene complexes; crystallographic characterisation and Lewis acid catalysis. Chem Commun (Camb) (2004) 0.95
A highly efficient and practical method for catalytic asymmetric vinylogous Mannich (AVM) reactions. Angew Chem Int Ed Engl (2006) 0.91
Aluminum-catalyzed asymmetric alkylations of pyridyl-substituted alkynyl ketones with dialkylzinc reagents. J Am Chem Soc (2008) 0.88
Direct Copper-Free Domino Conjugate Addition-Cycloallylation using Organozinc Reagents. Adv Synth Catal (2008) 0.80
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23
The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
Molybdenum and tungsten imido alkylidene complexes as efficient olefin-metathesis catalysts. Angew Chem Int Ed Engl (2003) 4.01
Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation. J Neurosci (2006) 3.84
Highly efficient molybdenum-based catalysts for enantioselective alkene metathesis. Nature (2008) 3.36
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature (2013) 3.22
Whole-genome sequence of Schistosoma haematobium. Nat Genet (2012) 2.91
Catalytic Z-selective olefin cross-metathesis for natural product synthesis. Nature (2011) 2.89
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Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Am J Respir Crit Care Med (2009) 2.53
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Nat Biotechnol (2011) 2.37
IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma. J Immunol (2008) 2.17
Highly Z- and enantioselective ring-opening/cross-metathesis reactions catalyzed by stereogenic-at-Mo adamantylimido complexes. J Am Chem Soc (2009) 2.17
Ascaris suum draft genome. Nature (2011) 2.16
Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model. Cardiovasc Drugs Ther (2014) 2.16
Enantioselective silyl protection of alcohols catalysed by an amino-acid-based small molecule. Nature (2006) 2.16
Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells. Proc Natl Acad Sci U S A (2011) 2.01
Highly Z-selective metathesis homocoupling of terminal olefins. J Am Chem Soc (2009) 2.01
PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. J Mol Cell Biol (2009) 2.00
Enhancement of learning and memory by elevating brain magnesium. Neuron (2010) 2.00
Incoherent-light temporal stretching of high-speed intensity waveforms. Opt Lett (2014) 1.96
Dipyrrolyl precursors to bisalkoxide molybdenum olefin metathesis catalysts. J Am Chem Soc (2006) 1.94
CH4 and N2O emissions from Spartina alterniflora and Phragmites australis in experimental mesocosms. Chemosphere (2007) 1.91
Experience-dependent modification of a central amygdala fear circuit. Nat Neurosci (2013) 1.88
A geminivirus-related DNA mycovirus that confers hypovirulence to a plant pathogenic fungus. Proc Natl Acad Sci U S A (2010) 1.87
Discovering transcription factor binding sites in highly repetitive regions of genomes with multi-read analysis of ChIP-Seq data. PLoS Comput Biol (2011) 1.86
Z-selective olefin metathesis processes catalyzed by a molybdenum hexaisopropylterphenoxide monopyrrolide complex. J Am Chem Soc (2009) 1.83
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A readily available chiral Ag-based N-heterocyclic carbene complex for use in efficient and highly enantioselective Ru-catalyzed olefin metathesis and Cu-catalyzed allylic alkylation reactions. J Am Chem Soc (2005) 1.78
Design and stereoselective preparation of a new class of chiral olefin metathesis catalysts and application to enantioselective synthesis of quebrachamine: catalyst development inspired by natural product synthesis. J Am Chem Soc (2009) 1.77
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. Am J Pathol (2005) 1.76
Competition between phasic and asynchronous release for recovered synaptic vesicles at developing hippocampal autaptic synapses. J Neurosci (2004) 1.76
All-carbon quaternary stereogenic centers by enantioselective cu-catalyzed conjugate additions promoted by a chiral N-heterocyclic carbene. Angew Chem Int Ed Engl (2007) 1.76
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights. PLoS Biol (2010) 1.74
Efficient boron-copper additions to aryl-substituted alkenes promoted by NHC-based catalysts. enantioselective Cu-catalyzed hydroboration reactions. J Am Chem Soc (2009) 1.74
Application of the level-set method to the implicit solvation of nonpolar molecules. J Chem Phys (2007) 1.73
ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. Cancer Cell (2012) 1.71
Human pregnancy up-regulates Tim-3 in innate immune cells for systemic immunity. J Immunol (2009) 1.68
Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation. J Biol Chem (2007) 1.65
Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS One (2009) 1.65
Optimal vaccination strategies for 2009 pandemic H1N1 and seasonal influenza vaccines in humans. Vaccine (2010) 1.65
SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood (2008) 1.63
Synthesis of monoalkoxide monopyrrolyl complexes Mo(NR)(CHR')(OR'')(pyrrolyl): enyne metathesis with high oxidation state catalysts. J Am Chem Soc (2007) 1.63
Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. J Immunol (2006) 1.62
Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. J Neurotrauma (2008) 1.62
Insights into salt tolerance from the genome of Thellungiella salsuginea. Proc Natl Acad Sci U S A (2012) 1.62
Immediate autotransplantation of mandibular third molar in China. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 1.60
Chiral Ru-based complexes for asymmetric olefin metathesis: enhancement of catalyst activity through steric and electronic modifications. J Am Chem Soc (2003) 1.60
Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring beta-substituted cyclic enones. Angew Chem Int Ed Engl (2008) 1.59
Ecosystem carbon stock influenced by plantation practice: implications for planting forests as a measure of climate change mitigation. PLoS One (2010) 1.51
Vicinal diboronates in high enantiomeric purity through tandem site-selective NHC-Cu-catalyzed boron-copper additions to terminal alkynes. J Am Chem Soc (2009) 1.51
Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis. Nature (2011) 1.50
Highly site- and enantioselective Cu-catalyzed allylic alkylation reactions with easily accessible vinylaluminum reagents. J Am Chem Soc (2007) 1.48
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Electrostatic free energy and its variations in implicit solvent models. J Phys Chem B (2008) 1.45
Enantioselective synthesis of allylboronates bearing a tertiary or quaternary B-substituted stereogenic carbon by NHC-Cu-catalyzed substitution reactions. J Am Chem Soc (2010) 1.44
Cu-catalyzed asymmetric allylic alkylations of aromatic and aliphatic phosphates with alkylzinc reagents. An effective method for enantioselective synthesis of tertiary and quaternary carbons. J Am Chem Soc (2004) 1.44
Chiral N-heterocyclic carbenes in natural product synthesis: application of Ru-catalyzed asymmetric ring-opening/cross-metathesis and Cu-catalyzed allylic alkylation to total synthesis of baconipyrone C. Angew Chem Int Ed Engl (2007) 1.43
Enantioselective synthesis of cyclic amides and amines through mo-catalyzed asymmetric ring-closing metathesis. J Am Chem Soc (2005) 1.42
Prophylaxis against hepatitis B virus recurrence after liver transplantation for hepatitis B virus-related end-stage liver diseases with severe hypersplenism and splenomegaly: role of splenectomy. J Surg Res (2012) 1.41
Small-for-size syndrome after living donor liver transplantation: successful treatment with a transjugular intrahepatic portosystemic shunt. Liver Transpl (2012) 1.41
Effects of temperature on the development and population growth of the sycamore lace bug, Corythucha ciliata. J Insect Sci (2011) 1.41
A practical method for enantioselective synthesis of all-carbon quaternary stereogenic centers through NHC-Cu-catalyzed conjugate additions of alkyl- and arylzinc reagents to beta-substituted cyclic enones. J Am Chem Soc (2006) 1.40
The significance of degenerate processes to enantioselective olefin metathesis reactions promoted by stereogenic-at-Mo complexes. J Am Chem Soc (2009) 1.37
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia. J Immunol (2004) 1.36
Responses of ecosystem nitrogen cycle to nitrogen addition: a meta-analysis. New Phytol (2010) 1.36
The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes Dev (2009) 1.35
Simple organic molecules as catalysts for enantioselective synthesis of amines and alcohols. Nature (2013) 1.34
Site- and enantioselective formation of allene-bearing tertiary or quaternary carbon stereogenic centers through NHC-Cu-catalyzed allylic substitution. J Am Chem Soc (2012) 1.33
Enantioselective total synthesis of clavirolide C. Applications of Cu-catalyzed asymmetric conjugate additions and Ru-catalyzed ring-closing metathesis. J Am Chem Soc (2008) 1.33
Chitosan modification and pharmaceutical/biomedical applications. Mar Drugs (2010) 1.33
Efficient enantioselective synthesis of functionalized tetrahydropyrans by Ru-catalyzed asymmetric ring-opening metathesis/cross-metathesis (AROM/CM). J Am Chem Soc (2004) 1.32
Comparison of Ru- and Mo-based chiral olefin metathesis catalysts. Complementarity in asymmetric ring-opening/cross-metathesis reactions of oxa- and azabicycles. Org Lett (2007) 1.32
Bidentate NHC-based chiral ligands for efficient Cu-catalyzed enantioselective allylic alkylations: structure and activity of an air-stable chiral Cu complex. J Am Chem Soc (2004) 1.32
Efficient and practical Ag-catalyzed cycloadditions between arylimines and the Danishefsky diene. J Am Chem Soc (2003) 1.30
Different responses of soil respiration and its components to nitrogen addition among biomes: a meta-analysis. Glob Chang Biol (2014) 1.28
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. EMBO Mol Med (2010) 1.27
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Inversion of configuration at the metal in diastereomeric imido alkylidene monoaryloxide monopyrrolide complexes of molybdenum. J Am Chem Soc (2009) 1.26
Monodentate non-C(2)-symmetric chiral N-heterocyclic carbene complexes for enantioselective synthesis. Cu-catalyzed conjugate additions of aryl- and alkenylsilylfluorides to cyclic enones. J Org Chem (2009) 1.24
Coupling the Level-Set Method with Molecular Mechanics for Variational Implicit Solvation of Nonpolar Molecules. J Chem Theory Comput (2009) 1.23
Enol ethers as substrates for efficient Z- and enantioselective ring-opening/cross-metathesis reactions promoted by stereogenic-at-Mo complexes: utility in chemical synthesis and mechanistic attributes. J Am Chem Soc (2012) 1.23
Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion. J Biol Chem (2009) 1.23
Inhaled ethyl nitrite prevents hyperoxia-impaired postnatal alveolar development in newborn rats. Am J Respir Crit Care Med (2007) 1.23
Room Temperature Z-Selective Homocoupling of α Olefins by Tungsten Catalysts. Organometallics (2011) 1.22
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Enantioselective synthesis of medium-ring heterocycles, tertiary ethers, and tertiary alcohols by Mo-catalyzed ring-closing metathesis. J Am Chem Soc (2002) 1.22
Interfaces and hydrophobic interactions in receptor-ligand systems: A level-set variational implicit solvent approach. J Chem Phys (2009) 1.22
Alpha-selective Ni-catalyzed hydroalumination of aryl- and alkyl-substituted terminal alkynes: practical syntheses of internal vinyl aluminums, halides, or boronates. J Am Chem Soc (2010) 1.22
Alkylidene and metalacyclic complexes of tungsten that contain a chiral biphenoxide ligand. synthesis, asymmetric ring-closing metathesis, and mechanistic investigations. J Am Chem Soc (2003) 1.21
Synthesis of Z-(pinacolato)allylboron and Z-(pinacolato)alkenylboron compounds through stereoselective catalytic cross-metathesis. J Am Chem Soc (2013) 1.21
Endo-selective enyne ring-closing metathesis promoted by stereogenic-at-Mo monoalkoxide and monoaryloxide complexes. Efficient synthesis of cyclic dienes not accessible through reactions with Ru carbenes. J Am Chem Soc (2009) 1.21
Diphenylamido Precursors to Bisalkoxide Molybdenum Olefin Metathesis Catalysts. Organometallics (2006) 1.21
Enantioselective synthesis of homoallylic amines through reactions of (pinacolato)allylborons with aryl-, heteroaryl-, alkyl-, or alkene-substituted aldimines catalyzed by chiral C1-symmetric NHC-Cu complexes. J Am Chem Soc (2011) 1.21