Leo L M Poon

Author PubWeight™ 136.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol 2005 9.13
2 Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol 2003 9.09
3 Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS One 2008 6.98
4 A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 2011 5.66
5 Three Indonesian clusters of H5N1 virus infection in 2005. N Engl J Med 2006 5.14
6 Lung pathology of fatal severe acute respiratory syndrome. Lancet 2003 5.02
7 Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol 2013 4.98
8 Dating the emergence of pandemic influenza viruses. Proc Natl Acad Sci U S A 2009 4.36
9 Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans. J Clin Virol 2009 4.10
10 MERS coronaviruses in dromedary camels, Egypt. Emerg Infect Dis 2014 3.64
11 The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature 2013 3.60
12 Highly conserved protective epitopes on influenza B viruses. Science 2012 3.47
13 Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. Nat Genet 2005 2.82
14 MERS coronavirus in dromedary camel herd, Saudi Arabia. Emerg Infect Dis 2014 2.47
15 Long-term evolution and transmission dynamics of swine influenza A virus. Nature 2011 2.39
16 Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets. Proc Natl Acad Sci U S A 2011 2.04
17 Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. J Virol 2005 1.76
18 Avian coronavirus in wild aquatic birds. J Virol 2011 1.73
19 Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures. J Virol 2013 1.68
20 Tropism and innate host responses of the 2009 pandemic H1N1 influenza virus in ex vivo and in vitro cultures of human conjunctiva and respiratory tract. Am J Pathol 2010 1.67
21 Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK. J Immunol 2009 1.66
22 The nsp9 replicase protein of SARS-coronavirus, structure and functional insights. Structure 2004 1.55
23 Detection of diverse astroviruses from bats in China. J Gen Virol 2009 1.46
24 Hyperinduction of cyclooxygenase-2-mediated proinflammatory cascade: a mechanism for the pathogenesis of avian influenza H5N1 infection. J Infect Dis 2008 1.46
25 Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants. PLoS Med 2006 1.34
26 Mass extinctions, biodiversity and mitochondrial function: are bats 'special' as reservoirs for emerging viruses? Curr Opin Virol 2011 1.33
27 Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS. PLoS Med 2006 1.31
28 Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus. BMC Evol Biol 2010 1.28
29 Influenza A virus expresses high levels of an unusual class of small viral leader RNAs in infected cells. MBio 2010 1.27
30 Characterization of a novel gyrovirus in human stool and chicken meat. J Clin Virol 2012 1.26
31 Full factorial analysis of mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation. PLoS One 2009 1.22
32 Reliable universal RT-PCR assays for studying influenza polymerase subunit gene sequences from all 16 haemagglutinin subtypes. J Virol Methods 2007 1.20
33 Absence of MERS-Coronavirus in Bactrian Camels, Southern Mongolia, November 2014. Emerg Infect Dis 2015 1.17
34 Development of a safe neutralization assay for SARS-CoV and characterization of S-glycoprotein. Virology 2004 1.17
35 Detection of novel astroviruses in urban brown rats and previously known astroviruses in humans. J Gen Virol 2010 1.17
36 Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans. J Gen Virol 2009 1.16
37 Comparison of the NucliSens easyMAG and Qiagen BioRobot 9604 nucleic acid extraction systems for detection of RNA and DNA respiratory viruses in nasopharyngeal aspirate samples. J Clin Microbiol 2008 1.13
38 The viruses of wild pigeon droppings. PLoS One 2013 1.12
39 A case for the ancient origin of coronaviruses. J Virol 2013 1.12
40 Initial viral load and the outcomes of SARS. CMAJ 2004 1.11
41 Emergence and dissemination of a swine H3N2 reassortant influenza virus with 2009 pandemic H1N1 genes in pigs in China. J Virol 2011 1.09
42 Biology of influenza a virus. Ann N Y Acad Sci 2007 1.07
43 Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma). J Interferon Cytokine Res 2004 1.05
44 Loop-mediated isothermal amplification for influenza A (H5N1) virus. Emerg Infect Dis 2007 1.04
45 Detection of highly pathogenic influenza and pandemic influenza virus in formalin fixed tissues by immunohistochemical methods. J Virol Methods 2011 1.03
46 Lack of middle East respiratory syndrome coronavirus transmission from infected camels. Emerg Infect Dis 2015 1.01
47 Serial analysis of the plasma concentration of SARS coronavirus RNA in pediatric patients with severe acute respiratory syndrome. Clin Chem 2003 0.99
48 The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5' to 3' viral helicases. J Biol Chem 2003 0.98
49 Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels in Nigeria, 2015. Euro Surveill 2015 0.97
50 A novel small-molecule inhibitor of the avian influenza H5N1 virus determined through computational screening against the neuraminidase. J Med Chem 2009 0.97
51 Tissue tropism of swine influenza viruses and reassortants in ex vivo cultures of the human respiratory tract and conjunctiva. J Virol 2011 0.93
52 A novel group of avian astroviruses in wild aquatic birds. J Virol 2012 0.90
53 SARS coronavirus 8b reduces viral replication by down-regulating E via an ubiquitin-independent proteasome pathway. Microbes Infect 2010 0.90
54 Viral reassortment as an information exchange between viral segments. Proc Natl Acad Sci U S A 2012 0.90
55 Entry of influenza A Virus with a α2,6-linked sialic acid binding preference requires host fibronectin. J Virol 2012 0.89
56 Rapid genotyping of swine influenza viruses. Emerg Infect Dis 2011 0.89
57 Swine influenza in Sri Lanka. Emerg Infect Dis 2013 0.89
58 The evolving threat of influenza viruses of animal origin and the challenges in developing appropriate diagnostics. Clin Chem 2012 0.88
59 Inhibition of SARS-associated coronavirus infection and replication by RNA interference. JAMA 2003 0.88
60 Genogroup I and II picobirnaviruses in respiratory tracts of pigs. Emerg Infect Dis 2011 0.87
61 Molecular detection of human H7N9 influenza A virus causing outbreaks in China. Clin Chem 2013 0.87
62 Evaluation of novel H1N1-specific primer-probe sets using commercial RT-PCR mixtures and a premixed reaction stored in a lyophilized format. J Virol Methods 2010 0.86
63 Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans. Virol J 2008 0.85
64 IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection. Proc Natl Acad Sci U S A 2014 0.85
65 Asymptomatic MERS-CoV Infection in Humans Possibly Linked to Infected Dromedaries Imported from Oman to United Arab Emirates, May 2015. Emerg Infect Dis 2015 0.84
66 BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses. J Antimicrob Chemother 2010 0.83
67 The emergence of human coronavirus EMC: how scared should we be? MBio 2013 0.80
68 Transgenic plant-derived siRNAs can suppress propagation of influenza virus in mammalian cells. FEBS Lett 2004 0.79
69 A statistical strategy to identify recombinant viral ribonucleoprotein of avian, human, and swine influenza A viruses with elevated polymerase activity. Influenza Other Respir Viruses 2013 0.79
70 The ins and outs of fetal DNA in maternal plasma. Lancet 2003 0.78
71 Molecular epidemiology of influenza A(H1N1)pdm09 virus among humans and swine, Sri Lanka. Emerg Infect Dis 2014 0.76
72 Detection of SARS coronavirus in humans and animals by conventional and quantitative (real time) reverse transcription polymerase chain reactions. Methods Mol Biol 2008 0.76
73 Transmissibility of pandemic H1N1 and genetically related swine influenza viruses in ferrets. Influenza Other Respir Viruses 2011 0.76
74 MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea, 2015. Emerg Infect Dis 2017 0.76
75 A novel molecular test for influenza B virus detection and lineage differentiation. J Med Virol 2014 0.75
76 Use of fractional factorial design to study the compatibility of viral ribonucleoprotein gene segments of human H7N9 virus and circulating human influenza subtypes. Influenza Other Respir Viruses 2014 0.75
77 DNA intercalator stimulates influenza transcription and virus replication. Virol J 2011 0.75
78 Detection of SARS coronavirus. Methods Mol Biol 2011 0.75
79 Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virus. Mol Pharm 2015 0.75