Published in Biochimie on May 20, 2009
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Locking and unlocking of ribosomal motions. Cell (2003) 6.59
The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell (2003) 6.01
Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy. Nat Struct Biol (2003) 3.77
The cryo-EM structure of a translation initiation complex from Escherichia coli. Cell (2005) 2.91
Selective charging of tRNA isoacceptors explains patterns of codon usage. Science (2003) 2.81
Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis. Proc Natl Acad Sci U S A (2009) 2.69
Fast evaluation of fluctuations in biochemical networks with the linear noise approximation. Genome Res (2003) 2.63
Structure of the Escherichia coli ribosomal termination complex with release factor 2. Nature (2003) 2.54
Selective charging of tRNA isoacceptors induced by amino-acid starvation. EMBO Rep (2005) 2.48
A cryo-electron microscopic study of ribosome-bound termination factor RF2. Nature (2003) 2.42
Regulatory nascent peptides in the ribosomal tunnel. Cell (2002) 2.41
The hemK gene in Escherichia coli encodes the N(5)-glutamine methyltransferase that modifies peptide release factors. EMBO J (2002) 2.37
Peptidyl-tRNA regulates the GTPase activity of translation factors. Cell (2003) 2.25
The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol (2003) 2.23
Termination of translation: interplay of mRNA, rRNAs and release factors? EMBO J (2003) 2.20
Slow peptide bond formation by proline and other N-alkylamino acids in translation. Proc Natl Acad Sci U S A (2008) 2.11
Release of peptide promoted by the GGQ motif of class 1 release factors regulates the GTPase activity of RF3. Mol Cell (2002) 1.98
Near-critical phenomena in intracellular metabolite pools. Biophys J (2003) 1.92
RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors. Cell (2007) 1.89
The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life. PLoS One (2011) 1.70
The kinetics of ribosomal peptidyl transfer revisited. Mol Cell (2008) 1.70
Splitting of the posttermination ribosome into subunits by the concerted action of RRF and EF-G. Mol Cell (2005) 1.69
Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs. J Biol (2005) 1.67
How initiation factors tune the rate of initiation of protein synthesis in bacteria. EMBO J (2006) 1.67
Ribosome rescue by tmRNA requires truncated mRNAs. J Mol Biol (2004) 1.63
Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol Cell (2005) 1.58
How initiation factors maximize the accuracy of tRNA selection in initiation of bacterial protein synthesis. Mol Cell (2006) 1.58
Ribosome formation from subunits studied by stopped-flow and Rayleigh light scattering. Biol Proced Online (2004) 1.55
The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesis. EMBO J (2003) 1.54
The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure. Mol Cell (2005) 1.53
The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer. FEBS Lett (2005) 1.52
Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset. J Struct Biol (2004) 1.46
Lys34 of translation elongation factor EF-P is hydroxylated by YfcM. Nat Chem Biol (2012) 1.45
Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome. J Cell Biol (2003) 1.45
Cell division in Escherichia coli cultures monitored at single cell resolution. BMC Microbiol (2008) 1.41
Age of inoculum strongly influences persister frequency and can mask effects of mutations implicated in altered persistence. J Bacteriol (2011) 1.38
Phylogenetic distribution of translational GTPases in bacteria. BMC Genomics (2007) 1.35
Genetic code translation displays a linear trade-off between efficiency and accuracy of tRNA selection. Proc Natl Acad Sci U S A (2011) 1.31
Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P. Proc Natl Acad Sci U S A (2013) 1.30
The essential role of the invariant GGQ motif in the function and stability in vivo of bacterial release factors RF1 and RF2. Mol Microbiol (2003) 1.29
Pre-binding of small protein B to a stalled ribosome triggers trans-translation. J Biol Chem (2004) 1.29
Translation initiation region sequence preferences in Escherichia coli. BMC Mol Biol (2007) 1.28
Rate and accuracy of bacterial protein synthesis revisited. Curr Opin Microbiol (2008) 1.26
pH-sensitivity of the ribosomal peptidyl transfer reaction dependent on the identity of the A-site aminoacyl-tRNA. Proc Natl Acad Sci U S A (2010) 1.23
The frequency of persisters in Escherichia coli reflects the kinetics of awakening from dormancy. J Bacteriol (2010) 1.22
Over expression of a tRNA(Leu) isoacceptor changes charging pattern of leucine tRNAs and reveals new codon reading. J Mol Biol (2005) 1.22
Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. EMBO J (2008) 1.21
Preferred and avoided codon pairs in three domains of life. BMC Genomics (2008) 1.19
Complementary roles of initiation factor 1 and ribosome recycling factor in 70S ribosome splitting. EMBO J (2008) 1.17
A time-resolved investigation of ribosomal subunit association. J Mol Biol (2005) 1.16
Class-1 release factor eRF1 promotes GTP binding by class-2 release factor eRF3. Biochimie (2006) 1.14
Near-critical behavior of aminoacyl-tRNA pools in E. coli at rate-limiting supply of amino acids. Biophys J (2004) 1.11
Interactions of the release factor RF1 with the ribosome as revealed by cryo-EM. J Mol Biol (2006) 1.11
The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome. RNA (2007) 1.10
Erythromycin- and chloramphenicol-induced ribosomal assembly defects are secondary effects of protein synthesis inhibition. Antimicrob Agents Chemother (2008) 1.09
Mapping the interaction of SmpB with ribosomes by footprinting of ribosomal RNA. Nucleic Acids Res (2005) 1.08
Comment on "The mechanism for activation of GTP hydrolysis on the ribosome". Science (2011) 1.07
The Escherichia coli mqsR and ygiT genes encode a new toxin-antitoxin pair. J Bacteriol (2010) 1.06
Kinetics of macrolide action: the josamycin and erythromycin cases. J Biol Chem (2004) 1.06
Cofactor dependent conformational switching of GTPases. Biophys J (2008) 1.04
Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits. J Mol Biol (2007) 1.00
Positive allosteric feedback regulation of the stringent response enzyme RelA by its product. EMBO Rep (2012) 0.99
The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form. Proc Natl Acad Sci U S A (2008) 0.98
Thermodynamic characterization of ppGpp binding to EF-G or IF2 and of initiator tRNA binding to free IF2 in the presence of GDP, GTP, or ppGpp. J Mol Biol (2010) 0.98
The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy. Dement Geriatr Cogn Disord (2004) 0.97
Ribosome degradation in growing bacteria. EMBO Rep (2011) 0.97
Stop codon recognition and interactions with peptide release factor RF3 of truncated and chimeric RF1 and RF2 from Escherichia coli. Mol Microbiol (2003) 0.97
What makes ribosome-mediated transcriptional attenuation sensitive to amino acid limitation? PLoS Comput Biol (2005) 0.97
Trigger factor binding to ribosomes with nascent peptide chains of varying lengths and sequences. J Biol Chem (2006) 0.97
Transcriptional cross-activation between toxin-antitoxin systems of Escherichia coli. BMC Microbiol (2013) 0.96
Targeting and insertion of heterologous membrane proteins in E. coli. Biochimie (2003) 0.94
Highly expressed proteins have an increased frequency of alanine in the second amino acid position. BMC Genomics (2006) 0.93
Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. Mol Microbiol (2011) 0.93
Distinction between the Cfr methyltransferase conferring antibiotic resistance and the housekeeping RlmN methyltransferase. Antimicrob Agents Chemother (2013) 0.93
The molecular mechanism of peptide-mediated erythromycin resistance. J Biol Chem (2006) 0.92
Bistable bacterial growth rate in response to antibiotics with low membrane permeability. Phys Rev Lett (2006) 0.92
tmRNA.SmpB complex mimics native aminoacyl-tRNAs in the A site of stalled ribosomes. J Struct Biol (2009) 0.92
The impact of aminoglycosides on the dynamics of translation elongation. Cell Rep (2013) 0.92
A Swedish family with de novo alpha-synuclein A53T mutation: evidence for early cortical dysfunction. Parkinsonism Relat Disord (2009) 0.91
Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits. EMBO J (2010) 0.91
Structure probing of tmRNA in distinct stages of trans-translation. RNA (2007) 0.91
tmRNA-induced release of messenger RNA from stalled ribosomes. J Mol Biol (2005) 0.91
Single molecule tracking fluorescence microscopy in mitochondria reveals highly dynamic but confined movement of Tom40. Sci Rep (2011) 0.90
GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding. Nucleic Acids Res (2009) 0.90
tmRNA decreases the bactericidal activity of aminoglycosides and the susceptibility to inhibitors of cell wall synthesis. RNA Biol (2005) 0.90
Erythromycin resistance by L4/L22 mutations and resistance masking by drug efflux pump deficiency. EMBO J (2009) 0.89
Inefficient delivery but fast peptide bond formation of unnatural L-aminoacyl-tRNAs in translation. J Am Chem Soc (2012) 0.87