Published in FEBS Lett on February 07, 2005
Simulating movement of tRNA into the ribosome during decoding. Proc Natl Acad Sci U S A (2005) 2.91
GTPase activation of elongation factor EF-Tu by the ribosome during decoding. EMBO J (2009) 2.71
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Structure of the mammalian 80S ribosome at 8.7 A resolution. Structure (2008) 2.11
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Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome. J Mol Biol (2010) 1.47
Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu. Q Rev Biophys (2009) 1.45
Controlling RNA self-assembly to form filaments. Nucleic Acids Res (2006) 1.33
Exploration of parameters in cryo-EM leading to an improved density map of the E. coli ribosome. J Struct Biol (2008) 1.28
Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. EMBO J (2008) 1.21
The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift. Nucleic Acids Res (2007) 1.21
Biomolecular dynamics: order-disorder transitions and energy landscapes. Rep Prog Phys (2012) 1.12
Release factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies. Nucleic Acids Res (2007) 1.09
Accommodation of tmRNA-SmpB into stalled ribosomes: a cryo-EM study. RNA (2009) 1.04
Mg2+ binding and archaeosine modification stabilize the G15 C48 Levitt base pair in tRNAs. RNA (2007) 1.03
Participation of the tRNA A76 hydroxyl groups throughout translation. Biochemistry (2006) 1.01
Perturbation of the tRNA tertiary core differentially affects specific steps of the elongation cycle. J Biol Chem (2008) 0.99
The ribosome structure controls and directs mRNA entry, translocation and exit dynamics. Phys Biol (2008) 0.93
Examinations of tRNA Range of Motion Using Simulations of Cryo-EM Microscopy and X-Ray Data. J Biophys (2011) 0.92
Simulating movement of tRNA through the ribosome during hybrid-state formation. J Chem Phys (2013) 0.87
Elastic properties of ribosomal RNA building blocks: molecular dynamics of the GTPase-associated center rRNA. Nucleic Acids Res (2007) 0.87
Mechanistic role of structurally dynamic regions in Dicistroviridae IGR IRESs. J Mol Biol (2009) 0.86
Steric complementarity in the decoding center is important for tRNA selection by the ribosome. J Mol Biol (2013) 0.86
Mutations of highly conserved bases in the peptidyltransferase center induce compensatory rearrangements in yeast ribosomes. RNA (2011) 0.86
tRNA residues evolved to promote translational accuracy. RNA (2013) 0.81
Capturing transition paths and transition states for conformational rearrangements in the ribosome. Biophys J (2014) 0.81
Steric interactions lead to collective tilting motion in the ribosome during mRNA-tRNA translocation. Nat Commun (2016) 0.80
Biochemical aspects of bacterial strategies for handling the incomplete translation processes. Front Microbiol (2014) 0.80
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Codon-dependent tRNA fluctuations monitored with fluorescence polarization. Biophys J (2010) 0.78
Molecular dynamics of ribosomal elongation factors G and Tu. Eur Biophys J (2010) 0.76
Functional interaction between bases C1049 in domain II and G2751 in domain VI of 23S rRNA in Escherichia coli ribosomes. Nucleic Acids Res (2008) 0.76
Exploring the balance between folding and functional dynamics in proteins and RNA. Int J Mol Sci (2015) 0.75
Movement in ribosome translocation. J Biol (2005) 0.75
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell (2010) 7.94
Locking and unlocking of ribosomal motions. Cell (2003) 6.59
The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell (2003) 6.01
Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization. Nat Methods (2006) 5.73
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell (2009) 5.49
Draft genome of the filarial nematode parasite Brugia malayi. Science (2007) 5.28
SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs. Nat Protoc (2008) 4.60
Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy. Nat Struct Biol (2003) 3.77
Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy. Proc Natl Acad Sci U S A (2003) 3.64
Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. EMBO J (2002) 3.57
Study of the structural dynamics of the E coli 70S ribosome using real-space refinement. Cell (2003) 3.03
Maximum-likelihood multi-reference refinement for electron microscopy images. J Mol Biol (2005) 3.00
The cryo-EM structure of a translation initiation complex from Escherichia coli. Cell (2005) 2.91
Structure of ratcheted ribosomes with tRNAs in hybrid states. Proc Natl Acad Sci U S A (2008) 2.77
Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis. Proc Natl Acad Sci U S A (2009) 2.69
Fast evaluation of fluctuations in biochemical networks with the linear noise approximation. Genome Res (2003) 2.63
Structure of the Escherichia coli ribosomal termination complex with release factor 2. Nature (2003) 2.54
Selective charging of tRNA isoacceptors induced by amino-acid starvation. EMBO Rep (2005) 2.48
The process of mRNA-tRNA translocation. Proc Natl Acad Sci U S A (2007) 2.45
A cryo-electron microscopic study of ribosome-bound termination factor RF2. Nature (2003) 2.42
Regulatory nascent peptides in the ribosomal tunnel. Cell (2002) 2.41
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. J Proteome Res (2008) 2.41
The hemK gene in Escherichia coli encodes the N(5)-glutamine methyltransferase that modifies peptide release factors. EMBO J (2002) 2.37
The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development. Proc Natl Acad Sci U S A (2004) 2.34
Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome. EMBO Rep (2004) 2.28
Peptidyl-tRNA regulates the GTPase activity of translation factors. Cell (2003) 2.25
The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol (2003) 2.23
Termination of translation: interplay of mRNA, rRNAs and release factors? EMBO J (2003) 2.20
Generation of induced pluripotent stem cell lines from Tibetan miniature pig. J Biol Chem (2009) 2.17
Risk factors for ERCP-related complications: a prospective multicenter study. Am J Gastroenterol (2009) 2.12
Slow peptide bond formation by proline and other N-alkylamino acids in translation. Proc Natl Acad Sci U S A (2008) 2.11
Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex. Proc Natl Acad Sci U S A (2007) 2.09
Release of peptide promoted by the GGQ motif of class 1 release factors regulates the GTPase activity of RF3. Mol Cell (2002) 1.98
RelB, a new partner of aryl hydrocarbon receptor-mediated transcription. Mol Endocrinol (2007) 1.95
Near-critical phenomena in intracellular metabolite pools. Biophys J (2003) 1.92
RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors. Cell (2007) 1.89
Fast maximum-likelihood refinement of electron microscopy images. Bioinformatics (2005) 1.83
Determination of signal-to-noise ratios and spectral SNRs in cryo-EM low-dose imaging of molecules. J Struct Biol (2009) 1.81
MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities. Arterioscler Thromb Vasc Biol (2011) 1.80
Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Ann Neurol (2003) 1.72
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9. Hepatol Res (2009) 1.70
The kinetics of ribosomal peptidyl transfer revisited. Mol Cell (2008) 1.70
Splitting of the posttermination ribosome into subunits by the concerted action of RRF and EF-G. Mol Cell (2005) 1.69
Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs. J Biol (2005) 1.67
How initiation factors tune the rate of initiation of protein synthesis in bacteria. EMBO J (2006) 1.67
Ribosome rescue by tmRNA requires truncated mRNAs. J Mol Biol (2004) 1.63
Structure of the connector of bacteriophage T7 at 8A resolution: structural homologies of a basic component of a DNA translocating machinery. J Mol Biol (2005) 1.63
Averaging of electron subtomograms and random conical tilt reconstructions through likelihood optimization. Structure (2009) 1.59
Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol Cell (2005) 1.58
How initiation factors maximize the accuracy of tRNA selection in initiation of bacterial protein synthesis. Mol Cell (2006) 1.58
A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res (2007) 1.58
The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesis. EMBO J (2003) 1.54
The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure. Mol Cell (2005) 1.53
Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2. Hepatology (2014) 1.53
ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy. EMBO Rep (2014) 1.49
Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming. Nat Cell Biol (2013) 1.47
Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation. Glia (2004) 1.47
Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset. J Struct Biol (2004) 1.46
Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome. J Cell Biol (2003) 1.45
Over-expression of AEG-1 significantly associates with tumour aggressiveness and poor prognosis in human non-small cell lung cancer. J Pathol (2009) 1.43
Bead-based microarray analysis of microRNA expression in hepatocellular carcinoma: miR-338 is downregulated. Hepatol Res (2009) 1.42
Flexible fitting in 3D-EM guided by the structural variability of protein superfamilies. Structure (2006) 1.41
Generation of human induced pluripotent stem cells from umbilical cord matrix and amniotic membrane mesenchymal cells. J Biol Chem (2010) 1.41
Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: direct evidence for load-induced fluid flow. J Bone Miner Res (2011) 1.40
miR-124 inhibits cell proliferation in gastric cancer through down-regulation of SPHK1. J Pathol (2012) 1.38
Bier spots: six case reports. J Am Acad Dermatol (2009) 1.37
The Cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli. PLoS Biol (2011) 1.35
Mutant ADA2 in vasculopathies. N Engl J Med (2014) 1.33
Unsupervised classification of single particles by cluster tracking in multi-dimensional space. J Struct Biol (2006) 1.31
Genetic code translation displays a linear trade-off between efficiency and accuracy of tRNA selection. Proc Natl Acad Sci U S A (2011) 1.31
Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes. Cancer Res (2005) 1.30
Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication. EMBO J (2003) 1.30
The essential role of the invariant GGQ motif in the function and stability in vivo of bacterial release factors RF1 and RF2. Mol Microbiol (2003) 1.29
Pre-binding of small protein B to a stalled ribosome triggers trans-translation. J Biol Chem (2004) 1.29
Apoptotic cells protect mice against lipopolysaccharide-induced shock. J Immunol (2008) 1.29
Characteristics of organic phosphorus fractions in different trophic sediments of lakes from the middle and lower reaches of Yangtze River region and Southwestern Plateau, China. Environ Pollut (2007) 1.29
Exploration of parameters in cryo-EM leading to an improved density map of the E. coli ribosome. J Struct Biol (2008) 1.28
Lamina propria CD4+ T lymphocytes synergize with murine intestinal epithelial cells to enhance proinflammatory response against an intracellular pathogen. J Immunol (2002) 1.27
MicroRNA-9 reduces cell invasion and E-cadherin secretion in SK-Hep-1 cell. Med Oncol (2009) 1.26
Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors. Hum Mol Genet (2003) 1.26
Interleukin-8 modulates growth and invasiveness of estrogen receptor-negative breast cancer cells. Int J Cancer (2007) 1.26
Rate and accuracy of bacterial protein synthesis revisited. Curr Opin Microbiol (2008) 1.26
A symmetrical tetramer for S. aureus pyruvate carboxylase in complex with coenzyme A. Structure (2009) 1.26