Published in Nat Immunol on February 27, 2005
The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude. J Immunol (2012) 3.20
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J Exp Med (2008) 3.15
Heterologous immunity between viruses. Immunol Rev (2010) 2.20
A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies. Proc Natl Acad Sci U S A (2006) 2.00
Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity. J Clin Invest (2006) 1.64
A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition. J Exp Med (2006) 1.56
Early establishment of diverse T cell receptor profiles for influenza-specific CD8(+)CD62L(hi) memory T cells. Proc Natl Acad Sci U S A (2006) 1.33
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. Immunity (2015) 1.29
The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation. J Exp Med (2005) 1.28
Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides. Proc Natl Acad Sci U S A (2008) 1.24
Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populations. J Immunol (2010) 1.18
Contribution of T cell receptor affinity to overall avidity for virus-specific CD8+ T cell responses. Proc Natl Acad Sci U S A (2005) 1.16
Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition. Proc Natl Acad Sci U S A (2010) 1.13
The utility and limitations of current Web-available algorithms to predict peptides recognized by CD4 T cells in response to pathogen infection. J Immunol (2012) 1.13
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity. Mol Immunol (2007) 1.12
Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold. PLoS Pathog (2010) 1.06
Immune memory and aging: an infinite or finite resource? Curr Opin Immunol (2010) 1.05
Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope. J Immunol (2007) 1.01
Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses. Proc Natl Acad Sci U S A (2011) 0.98
Heterologous immunity: immunopathology, autoimmunity and protection during viral infections. Autoimmunity (2011) 0.98
Early priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and function. PLoS Pathog (2012) 0.95
Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides. J Virol (2011) 0.95
Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy. Proc Natl Acad Sci U S A (2008) 0.95
Random T-cell receptor recruitment in human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells from genetically identical twins infected with the same HIV-1 strain. J Virol (2007) 0.91
T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection. J Biol Chem (2010) 0.91
Real time detection of peptide-MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability. Mol Immunol (2010) 0.90
Limited maintenance of vaccine-induced simian immunodeficiency virus-specific CD8 T-cell receptor clonotypes after virus challenge. J Virol (2008) 0.89
Terminal deoxynucleotidyl transferase establishes and broadens antiviral CD8+ T cell immunodominance hierarchies. J Immunol (2008) 0.87
Expression, refolding and preliminary X-ray crystallographic analysis of equine MHC class I molecule complexed with an EIAV-Env CTL epitope. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.86
Effect of MHC class I diversification on influenza epitope-specific CD8+ T cell precursor frequency and subsequent effector function. J Immunol (2011) 0.85
Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proc Natl Acad Sci U S A (2013) 0.84
Tumors reveal their secrets to cytotoxic T cells. Proc Natl Acad Sci U S A (2006) 0.84
Reverse genetics modification of cytomegalovirus antigenicity and immunogenicity by CD8 T-cell epitope deletion and insertion. J Biomed Biotechnol (2010) 0.83
Paired TCRαβ analysis of virus-specific CD8(+) T cells exposes diversity in a previously defined 'narrow' repertoire. Immunol Cell Biol (2015) 0.83
Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Sci Rep (2014) 0.81
Accurate structure prediction of peptide-MHC complexes for identifying highly immunogenic antigens. Mol Immunol (2013) 0.80
Multiple distinct forms of CD8+ T cell cross-reactivity and specificities revealed after 2009 H1N1 influenza A virus infection in mice. PLoS One (2012) 0.79
Influence of dominant HIV-1 epitopes on HLA-A3/peptide complex formation. Proc Natl Acad Sci U S A (2006) 0.78
Predictable alphabeta T-cell receptor selection toward an HLA-B*3501-restricted human cytomegalovirus epitope. J Virol (2007) 0.78
Complex T-cell receptor repertoire dynamics underlie the CD8+ T-cell response to HIV-1. J Virol (2014) 0.77
Favorite flavors of surfaces. Nat Immunol (2005) 0.75
Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8(+) T cell epitope. Nat Struct Mol Biol (2017) 0.75
Epitope shifting of gp90-specific cellular immune responses in EIAV-infected ponies. Vet Immunol Immunopathol (2014) 0.75
Surgical mask vs N95 respirator for preventing influenza among health care workers: a randomized trial. JAMA (2009) 7.61
CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature (2007) 5.31
Linear ubiquitination prevents inflammation and regulates immune signalling. Nature (2011) 4.85
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity (2009) 4.51
Eight-plasmid system for rapid generation of influenza virus vaccines. Vaccine (2002) 4.45
Effect of influenza vaccination of children on infection rates in Hutterite communities: a randomized trial. JAMA (2010) 4.21
MR1 presents microbial vitamin B metabolites to MAIT cells. Nature (2012) 3.71
TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci U S A (2009) 3.70
A question of self-preservation: immunopathology in influenza virus infection. Immunol Cell Biol (2007) 3.65
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. Nature (2006) 3.65
Cell-mediated protection in influenza infection. Emerg Infect Dis (2006) 3.62
A common fold mediates vertebrate defense and bacterial attack. Science (2007) 3.43
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol (2012) 3.42
A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity. Immunity (2003) 3.41
Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell-deficient mice. J Virol (2002) 3.21
Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol (2007) 3.19
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity (2013) 3.15
Structural determinants of T-cell receptor bias in immunity. Nat Rev Immunol (2006) 3.01
Replication and transmission of H9N2 influenza viruses in ferrets: evaluation of pandemic potential. PLoS One (2008) 2.86
Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell (2009) 2.84
Autoregulation of Parkin activity through its ubiquitin-like domain. EMBO J (2011) 2.75
More than one reason to rethink the use of peptides in vaccine design. Nat Rev Drug Discov (2007) 2.68
Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity (2009) 2.61
A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule. Nat Immunol (2007) 2.55
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide. Nat Immunol (2005) 2.52
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature (2012) 2.46
Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature (2012) 2.44
Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nat Immunol (2011) 2.42
Ubiquitin signalling in DNA replication and repair. Nat Rev Mol Cell Biol (2010) 2.41
The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood (2005) 2.41
The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition. Nat Immunol (2005) 2.38
Swine outbreak of pandemic influenza A virus on a Canadian research farm supports human-to-swine transmission. Clin Infect Dis (2011) 2.28
Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity. J Immunol (2004) 2.26
T cell allorecognition via molecular mimicry. Immunity (2009) 2.25
Pause on avian flu transmission research. Science (2012) 2.24
The 2.0-A crystal structure of eqFP611, a far red fluorescent protein from the sea anemone Entacmaea quadricolor. J Biol Chem (2003) 2.23
The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature (2010) 2.23
Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses. J Gen Virol (2005) 2.15
Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proc Natl Acad Sci U S A (2004) 2.15
The MACPF/CDC family of pore-forming toxins. Cell Microbiol (2008) 2.15
The collagen binding alpha1beta1 integrin VLA-1 regulates CD8 T cell-mediated immune protection against heterologous influenza infection. Immunity (2004) 2.13
Protection and compensation in the influenza virus-specific CD8+ T cell response. Proc Natl Acad Sci U S A (2003) 2.13
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin. Nature (2008) 2.11
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity (2011) 2.11
Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections. J Exp Med (2003) 2.07
The shaping of T cell receptor recognition by self-tolerance. Immunity (2009) 2.06
Avian influenza among waterfowl hunters and wildlife professionals. Emerg Infect Dis (2006) 2.05
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J Exp Med (2013) 2.04
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65. PLoS Pathog (2010) 2.03
Optimization of the MHC class I peptide cargo is dependent on tapasin. Immunity (2002) 2.02
A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies. Proc Natl Acad Sci U S A (2006) 2.00
Methods for comparing the diversity of samples of the T cell receptor repertoire. J Immunol Methods (2007) 1.98
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nat Immunol (2013) 1.95
Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B. Nature (2011) 1.94
A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity (2011) 1.94
Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope. Proc Natl Acad Sci U S A (2004) 1.92
Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion. J Clin Invest (2010) 1.92
Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease. Sci Transl Med (2010) 1.90
The fidelity, occasional promiscuity, and versatility of T cell receptor recognition. Immunity (2008) 1.89
Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. J Clin Invest (2006) 1.88
Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J (2009) 1.88