PubRank

Lingyun Wu

Author PubWeight™ 97.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science 2008 7.89
2 Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function. Proc Natl Acad Sci U S A 2011 1.82
3 Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2. Antioxid Redox Signal 2013 1.79
4 Sustained normalization of high blood pressure in spontaneously hypertensive rats by implanted hemin pump. Hypertension 2006 1.71
5 Pro-apoptotic effect of endogenous H2S on human aorta smooth muscle cells. FASEB J 2006 1.62
6 Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms. J Physiol 2005 1.59
7 H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem 2007 1.56
8 Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. J Biol Chem 2004 1.56
9 Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production. Proc Natl Acad Sci U S A 2012 1.49
10 Differentiation and hematopoietic-support of clonal cells in myelodysplastic syndromes. Leuk Lymphoma 2007 1.49
11 Increased expression of calcium-sensing receptors induced by ox-LDL amplifies apoptosis of cardiomyocytes during simulated ischaemia-reperfusion. Clin Exp Pharmacol Physiol 2010 1.45
12 Direct stimulation of K(ATP) channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells. Mol Pharmacol 2005 1.35
13 Interaction of hydrogen sulfide with ion channels. Clin Exp Pharmacol Physiol 2010 1.34
14 Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells. Biochem Biophys Res Commun 2006 1.31
15 Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose. Br J Pharmacol 2010 1.31
16 Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells. Cardiovasc Res 2010 1.31
17 Molecular mechanism for H(2)S-induced activation of K(ATP) channels. Antioxid Redox Signal 2010 1.28
18 Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis. Circulation 2013 1.26
19 Predicting DNA- and RNA-binding proteins from sequences with kernel methods. J Theor Biol 2009 1.23
20 Oxidative stress in hypertension. Clin Exp Hypertens 2005 1.23
21 Oxidative stress and aging: is methylglyoxal the hidden enemy? Can J Physiol Pharmacol 2010 1.16
22 Protective effect of hydrogen sulfide on balloon injury-induced neointima hyperplasia in rat carotid arteries. Am J Pathol 2007 1.13
23 Lipoic acid prevents hypertension, hyperglycemia, and the increase in heart mitochondrial superoxide production. Am J Hypertens 2003 1.12
24 Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. Ann Hematol 2010 1.11
25 Calcium and polyamine regulated calcium-sensing receptors in cardiac tissues. Eur J Biochem 2003 1.09
26 Methylglyoxal, protein binding and biological samples: are we getting the true measure? J Chromatogr B Analyt Technol Biomed Life Sci 2009 1.09
27 Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats. Diabetes 2011 1.06
28 Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats. J Hypertens 2008 1.06
29 Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase mediated by Lon protease. Proc Natl Acad Sci U S A 2013 1.06
30 Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors. Metabolism 2008 1.04
31 Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats. Mol Cell Biochem 2007 1.03
32 Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats. Kidney Int 2004 1.01
33 Hydrogen sulfide and the pathogenesis of atherosclerosis. Antioxid Redox Signal 2013 1.01
34 Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin Biochem 2007 1.00
35 Vascular methylglyoxal metabolism and the development of hypertension. J Hypertens 2005 1.00
36 Free radical generation by methylglyoxal in tissues. Drug Metabol Drug Interact 2008 0.99
37 Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells. Free Radic Biol Med 2005 0.99
38 Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats. Br J Pharmacol 2009 0.98
39 Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats. Nutr Res 2008 0.98
40 Methylglyoxal and advanced glycation endproducts: new therapeutic horizons? Recent Pat Cardiovasc Drug Discov 2007 0.98
41 Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome. Cardiovasc Res 2011 0.98
42 Structural and functional changes in human insulin induced by methylglyoxal. FASEB J 2006 0.98
43 H₂S is an endothelium-derived hyperpolarizing factor. Antioxid Redox Signal 2013 0.97
44 Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells. Biochem Pharmacol 2009 0.96
45 Increased neointimal formation in cystathionine gamma-lyase deficient mice: role of hydrogen sulfide in α5β1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells. J Mol Cell Cardiol 2011 0.95
46 Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats. Blood 2002 0.95
47 The pathogenic role of cystathionine γ-lyase/hydrogen sulfide in streptozotocin-induced diabetes in mice. Am J Pathol 2011 0.93
48 The role of endothelial cell adhesion molecules P-selectin, E-selectin and intercellular adhesion molecule-1 in leucocyte recruitment induced by exogenous methylglyoxal. Immunology 2012 0.91
49 Methylglyoxal mediates adipocyte proliferation by increasing phosphorylation of Akt1. PLoS One 2012 0.90
50 Altered expression of BK channel beta1 subunit in vascular tissues from spontaneously hypertensive rats. Am J Hypertens 2006 0.90
51 Methylglyoxal, oxidative stress, and hypertension. Can J Physiol Pharmacol 2006 0.90
52 Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells. Toxicol Appl Pharmacol 2011 0.89
53 Dietary approaches to positively influence fetal determinants of adult health. FASEB J 2005 0.89
54 Fructose-induced peroxynitrite production is mediated by methylglyoxal in vascular smooth muscle cells. Life Sci 2006 0.88
55 Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α. Br J Pharmacol 2012 0.87
56 Exogenous hydrogen sulfide attenuates diabetic myocardial injury through cardiac mitochondrial protection. Mol Cell Biochem 2012 0.87
57 Attenuation of hypertension development by aminoguanidine in spontaneously hypertensive rats: role of methylglyoxal. Am J Hypertens 2007 0.86
58 N-acetylcysteine improves nitric oxide and alpha-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats. Am J Hypertens 2003 0.85
59 Modulation of cardiac and aortic peroxisome proliferator-activated receptor-gamma expression by oxidative stress in chronically glucose-fed rats. Am J Hypertens 2006 0.85
60 Interaction of hydrogen sulfide and estrogen on the proliferation of vascular smooth muscle cells. PLoS One 2012 0.85
61 Melatonin alleviates secondary brain damage and neurobehavioral dysfunction after experimental subarachnoid hemorrhage: possible involvement of TLR4-mediated inflammatory pathway. J Pineal Res 2013 0.85
62 Arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an endothelial nitric-oxide synthase-independent mechanism. J Pharmacol Exp Ther 2012 0.84
63 Inhibition of vascular smooth muscle cell proliferation by chronic hemin treatment. Am J Physiol Heart Circ Physiol 2008 0.84
64 Cytogenetic response based on revised IPSS cytogenetic risk stratification and minimal residual disease monitoring by FISH in MDS patients treated with low-dose decitabine. Leuk Res 2013 0.84
65 Modification of Akt1 by methylglyoxal promotes the proliferation of vascular smooth muscle cells. FASEB J 2011 0.83
66 Increased methylglyoxal formation with upregulation of renin angiotensin system in fructose fed Sprague Dawley rats. PLoS One 2013 0.83
67 Interaction of methylglyoxal and hydrogen sulfide in rat vascular smooth muscle cells. Antioxid Redox Signal 2010 0.83
68 Modulation of methylglyoxal and glutathione by soybean isoflavones in mild streptozotocin-induced diabetic rats. Nutr Metab Cardiovasc Dis 2007 0.82
69 Flow cytometric scoring system (FCMSS) assisted diagnosis of myelodysplastic syndromes (MDS) and the biological significance of FCMSS-based immunophenotypes. Br J Haematol 2010 0.82
70 Aldolase B knockdown prevents high glucose-induced methylglyoxal overproduction and cellular dysfunction in endothelial cells. PLoS One 2012 0.81
71 Interaction of selective amino acid residues of K(ca) channels with carbon monoxide. Exp Biol Med (Maywood) 2003 0.81
72 Uncoupling of eNOS contributes to redox-sensitive leukocyte recruitment and microvascular leakage elicited by methylglyoxal. Biochem Pharmacol 2013 0.80
73 The dietary phase 2 protein inducer sulforaphane can normalize the kidney epigenome and improve blood pressure in hypertensive rats. Am J Hypertens 2011 0.80
74 Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes. Endocrinology 2012 0.80
75 A delayed yet durable response to very short lenalidomide therapy and unexpected clone redistribution in a case of myelodysplastic syndrome with del(5q) and del(20q). Leuk Res 2009 0.80
76 Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells. Cardiovasc Diabetol 2013 0.80
77 Hydrogen sulfide represses androgen receptor transactivation by targeting at the second zinc finger module. J Biol Chem 2014 0.80
78 Sulphonylureas induced vasorelaxation of mouse arteries. Eur J Pharmacol 2007 0.79
79 Hydrogen sulfide and the metabolic syndrome. Expert Rev Clin Pharmacol 2011 0.79
80 Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats. Can J Physiol Pharmacol 2011 0.79
81 Interleukin-17 enhances the production of interferon-γ and tumour necrosis factor-α by bone marrow T lymphocytes from patients with lower risk myelodysplastic syndromes. Eur J Haematol 2013 0.79
82 Overexpression of BMI1 confers clonal cells resistance to apoptosis and contributes to adverse prognosis in myelodysplastic syndrome. Cancer Lett 2011 0.78
83 Methylglyoxal, a reactive glucose metabolite, increases renin angiotensin aldosterone and blood pressure in male Sprague-Dawley rats. Am J Hypertens 2014 0.78
84 Involvement of dopamine D2 receptors activation in ischemic post-conditioning-induced cardioprotection through promoting PKC-ε particulate translocation in isolated rat hearts. Mol Cell Biochem 2013 0.78
85 Comparison of immunological abnormalities of lymphocytes in bone marrow in myelodysplastic syndrome (MDS) and aplastic anemia (AA). Intern Med 2010 0.77
86 The effect of the combination of bisphosphonates and conventional chemotherapy on bone metabolic markers in multiple myeloma patients. Hematology 2012 0.77
87 Increased renal methylglyoxal formation with down-regulation of PGC-1α-FBPase pathway in cystathionine γ-lyase knockout mice. PLoS One 2011 0.76
88 Tumor suppressor gene BLU is frequently downregulated by promoter hypermethylation in myelodysplastic syndrome. J Cancer Res Clin Oncol 2012 0.76
89 Pattern-selection based power analysis and discrimination of low- and high-grade myelodysplastic syndromes study using SNP arrays. PLoS One 2009 0.75
90 Up-regulation of aldolase A and methylglyoxal production in adipocytes. Br J Pharmacol 2013 0.75
91 The prevalence of carotid plaque with different stability and its association with metabolic syndrome in China: The Asymptomatic Polyvascular Abnormalities Community study. Medicine (Baltimore) 2016 0.75
92 The functional expression of calcium-sensing receptors in BRL cells and related signal transduction pathway responsible for intracellular calcium elevation. Mol Cell Biochem 2010 0.75
93 Conformational control in activation of an enediyne. J Am Chem Soc 2003 0.75
94 The effect of hydroxylamine on KATP channels in vascular smooth muscle and underlying mechanisms. Mol Pharmacol 2005 0.75
95 Ultrasound Standard Plane Detection Using a Composite Neural Network Framework. IEEE Trans Cybern 2017 0.75
96 Clonality investigation of morphologically dysplastic hematopoietic cells in myelodysplastic syndrome marrows. Int J Hematol 2008 0.75
97 The evaluation of iron overload through hepcidin level and its related factors in myelodysplastic syndromes. Hematology 2013 0.75
98 Isolation and structure characterization of related impurities in etimicin sulfate by LC/ESI-MS(n) and NMR. J Pharm Biomed Anal 2011 0.75
99 FUIQA: Fetal Ultrasound Image Quality Assessment With Deep Convolutional Networks. IEEE Trans Cybern 2017 0.75
100 Identification of a novel bacterial K(+) channel. J Membr Biol 2011 0.75
101 Wilms' tumor gene (WT1) is predominantly expressed in clonal hematopoietic cells in myelodysplastic syndromes. Leuk Lymphoma 2007 0.75