PubRank

Ian N M Day

Author PubWeight™ 160.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
2 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
3 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
4 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
5 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
6 C-reactive protein and its role in metabolic syndrome: mendelian randomisation study. Lancet 2005 5.51
7 Hardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studies. Am J Epidemiol 2009 4.70
8 Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models. Hum Mutat 2012 3.60
9 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
10 Association of C-reactive protein with blood pressure and hypertension: life course confounding and mendelian randomization tests of causality. Arterioscler Thromb Vasc Biol 2005 2.42
11 Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol 2013 2.18
12 Predicting the functional consequences of cancer-associated amino acid substitutions. Bioinformatics 2013 2.12
13 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet 2012 1.96
14 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
15 IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children. Biol Psychiatry 2011 1.59
16 The association of oestrogen receptor alpha-haplotypes with cardiovascular risk factors in the British Women's Heart and Health Study. Eur Heart J 2006 1.57
17 Dependence of deodorant usage on ABCC11 genotype: scope for personalized genetics in personal hygiene. J Invest Dermatol 2013 1.51
18 Use of genotype frequencies in medicated groups to investigate prescribing practice: APOE and statins as a proof of principle. Clin Chem 2011 1.49
19 Blood pressure loci identified with a gene-centric array. Am J Hum Genet 2011 1.44
20 Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. Eur Heart J 2012 1.30
21 The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants. PLoS One 2008 1.28
22 Genetic association study of BDNF in depression: finding from two cohort studies and a meta-analysis. Am J Med Genet B Neuropsychiatr Genet 2008 1.24
23 MIDAS: software for analysis and visualisation of interallelic disequilibrium between multiallelic markers. BMC Bioinformatics 2006 1.24
24 Influences of matrix metalloproteinase-3 gene variation on extent of coronary atherosclerosis and risk of myocardial infarction. J Am Coll Cardiol 2003 1.24
25 Lactase persistence-related genetic variant: population substructure and health outcomes. Eur J Hum Genet 2008 1.13
26 The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis. BMC Genet 2004 1.12
27 ACTN3 genotype, athletic status, and life course physical capability: meta-analysis of the published literature and findings from nine studies. Hum Mutat 2011 1.10
28 Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease. Hum Genet 2007 1.06
29 Genetic variants in the vitamin d receptor are associated with advanced prostate cancer at diagnosis: findings from the prostate testing for cancer and treatment study and a systematic review. Cancer Epidemiol Biomarkers Prev 2009 1.02
30 Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI. Eur J Hum Genet 2009 1.02
31 Exonization of AluYa5 in the human ACE gene requires mutations in both 3' and 5' splice sites and is facilitated by a conserved splicing enhancer. Nucleic Acids Res 2005 1.02
32 Prevalence and functionality of paucimorphic and private MC4R mutations in a large, unselected European British population, scanned by meltMADGE. Hum Mutat 2007 1.02
33 Variants in the human insulin gene that affect pre-mRNA splicing: is -23HphI a functional single nucleotide polymorphism at IDDM2? Diabetes 2006 1.01
34 Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits. Hum Mol Genet 2004 1.00
35 Independent effects of the -219 G>T and epsilon 2/ epsilon 3/ epsilon 4 polymorphisms in the apolipoprotein E gene on coronary artery disease: the Southampton Atherosclerosis Study. Eur J Hum Genet 2003 1.00
36 Evidence of multiple causal sites affecting weight in the IGF2-INS-TH region of human chromosome 11. Hum Genet 2002 0.99
37 Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circ Cardiovasc Genet 2011 0.99
38 Refining associations between TAS2R38 diplotypes and the 6-n-propylthiouracil (PROP) taste test: findings from the Avon Longitudinal Study of Parents and Children. BMC Genet 2007 0.99
39 A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes. Nucleic Acids Res 2002 0.98
40 CYP2A6, MAOA, DBH, DRD4, and 5HT2A genotypes, smoking behaviour and cotinine levels in 1518 UK adolescents. Pharmacogenet Genomics 2005 0.98
41 Ranking non-synonymous single nucleotide polymorphisms based on disease concepts. Hum Genomics 2014 0.98
42 Molecular and population analysis of natural selection on the human haptoglobin duplication. Ann Hum Genet 2012 0.98
43 Association between interleukin 1-beta promoter (-511) polymorphism and depressive symptoms in Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 2004 0.95
44 A pathway-based data integration framework for prediction of disease progression. Bioinformatics 2013 0.95
45 The association of the PON1 Q192R polymorphism with complications and outcomes of pregnancy: findings from the British Women's Heart and Health cohort study. Paediatr Perinat Epidemiol 2006 0.94
46 From a single whole exome read to notions of clinical screening: primary ciliary dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula. Ann Hum Genet 2012 0.94
47 Replication of IGF2-INS-TH*5 haplotype effect on obesity in older men and study of related phenotypes. Eur J Hum Genet 2006 0.94
48 Manual 768 or 384 well microplate gel 'dry' electrophoresis for PCR checking and SNP genotyping. Nucleic Acids Res 2003 0.92
49 Integrated single-label liquid-phase assay of APOE codons 112 and 158 and a lipoprotein study in British women. Clin Chem 2006 0.90
50 Polymorphism of the IGF2 gene, birth weight and grip strength in adult men. Age Ageing 2002 0.89
51 Evidence of admixture from haplotyping in an epidemiological study of UK Caucasian males: implications for association analyses. Hum Hered 2004 0.89
52 Molecular pathogenesis of subarachnoid haemorrhage. Int J Biochem Cell Biol 2003 0.88
53 Mutation scanning by meltMADGE: validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population. Genome Res 2005 0.87
54 Inflammation and not cardiovascular risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents. Arterioscler Thromb Vasc Biol 2012 0.86
55 Amplification ratio control system for copy number variation genotyping. Nucleic Acids Res 2011 0.85
56 An expectation-maximization program for determining allelic spectrum from CNV data (CoNVEM): insights into population allelic architecture and its mutational history. Hum Mutat 2010 0.82
57 A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array. Eur J Hum Genet 2012 0.82
58 A study of TH01 and IGF2-INS-TH haplotypes in relation to smoking initiation in three independent surveys. Pharmacogenet Genomics 2006 0.82
59 Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme. Aging Cell 2011 0.82
60 Microplate array diagonal gel electrophoresis for cohort studies of microsatellite loci. Biotechniques 2002 0.82
61 Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol. Gene 2012 0.82
62 The association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British Women's Heart and Health Study. J Epidemiol Community Health 2007 0.82
63 Quantitated transcript haplotypes (QTH) of AGTR1, reduced abundance of mRNA haplotypes containing 1166C (rs5186:A>C), and relevance to metabolic syndrome traits. Hum Mutat 2007 0.82
64 Very low PSA concentrations and deletions of the KLK3 gene. Clin Chem 2012 0.82
65 Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS). Dis Markers 2008 0.81
66 Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients. Hum Mol Genet 2007 0.81
67 A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme. PLoS One 2012 0.80
68 Non-replication of an association of Apolipoprotein E2 with sinistrality. Laterality 2012 0.80
69 Non-recombining chromosome Y haplogroups and centromeric HindIII RFLP in relation to blood pressure in 2,743 middle-aged Caucasian men from the UK. Hum Genet 2005 0.79
70 Insulin-like growth factor-I genotype and birthweight. Lancet 2002 0.79
71 Null mutation in human ciliary neurotrophic factor gene confers higher body mass index in males. Eur J Hum Genet 2002 0.79
72 Nonsense mutation in coiled-coil domain containing 151 gene (CCDC151) causes primary ciliary dyskinesia. Hum Mutat 2014 0.79
73 Interaction between birthweight and polymorphism in the calcium-sensing receptor gene in determination of adult bone mass: the Hertfordshire cohort study. J Rheumatol 2007 0.79
74 Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip. Circ Cardiovasc Genet 2012 0.79
75 Structural and population-based evaluations of TBC1D1 p.Arg125Trp. PLoS One 2013 0.79
76 Associations between a polymorphism in the pleiotropic GCKR and Age-related phenotypes: the HALCyon programme. PLoS One 2013 0.79
77 Associations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme. Age (Dordr) 2014 0.78
78 Haplotype of growth hormone and angiotensin I-converting enzyme genes, serum angiotensin I-converting enzyme and ventricular growth: pathway inference in pharmacogenetics. Pharmacogenet Genomics 2007 0.78
79 A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study. J Rheumatol 2009 0.78
80 Questioning INS VNTR role in obesity and diabetes: subclasses tag IGF2-INS-TH haplotypes; and -23HphI as a STEP (splicing and translational efficiency polymorphism). Physiol Genomics 2006 0.78
81 Typing dinucleotide repeat loci using microplate array diagonal gel electrophoresis: proof of principle. Electrophoresis 2004 0.77
82 Genome-wide data-mining of candidate human splice translational efficiency polymorphisms (STEPs) and an online database. PLoS One 2010 0.77
83 Sequential sentinel SNP Regional Association Plots (SSS-RAP): an approach for testing independence of SNP association signals using meta-analysis data. Ann Hum Genet 2013 0.77
84 Genetic markers of bone and joint health and physical capability in older adults: the HALCyon programme. Bone 2012 0.77
85 Comment on: Marchand and Polychronakos (2007) Evaluation of polymorphic splicing in the mechanism of the association of the insulin gene with diabetes: Diabetes 56:709-713. Diabetes 2007 0.76
86 MeltMADGE for mutation scanning of specific genes in population studies. Nat Protoc 2010 0.75
87 Genetic variants influencing biomarkers of nutrition are not associated with cognitive capability in middle-aged and older adults. J Nutr 2013 0.75
88 Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort. PLoS One 2009 0.75
89 Combination of His-tagged T4 endonuclease VII with microplate array diagonal gel electrophoresis for high-throughput mutation scanning. Clin Chem 2005 0.75
90 Population mutation scanning of human GHR by meltMADGE and identification of a paucimorphic variant. Genet Test Mol Biomarkers 2011 0.75
91 Analysis of potential genomic confounding in genetic association studies and an online genomic confounding browser (GCB). Ann Hum Genet 2011 0.75
92 Combination of 768-well microplate array diagonal gel electrophoresis with duplex PCR of X and Y chromosome markers for quality control of epidemiological DNA banks. Electrophoresis 2006 0.75