PubRank

Lude Franke

Author PubWeight™ 136.03‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet 2007 8.50
2 Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 2011 7.98
3 Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet 2008 7.63
4 Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 2010 6.90
5 Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet 2011 6.36
6 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 2013 4.71
7 High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet 2012 4.46
8 Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genet 2011 3.68
9 Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet 2011 3.65
10 Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet 2010 3.55
11 Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing. Hum Mol Genet 2010 3.50
12 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
13 Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP. Am J Hum Genet 2008 3.11
14 Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases. Am J Hum Genet 2007 2.89
15 ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Lancet Neurol 2007 2.80
16 Seventy-five genetic loci influencing the human red blood cell. Nature 2012 2.77
17 Using genome-wide pathway analysis to unravel the etiology of complex diseases. Genet Epidemiol 2009 2.72
18 Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat Genet 2005 2.71
19 Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. Nat Genet 2007 2.63
20 Copy-number variation in sporadic amyotrophic lateral sclerosis: a genome-wide screen. Lancet Neurol 2008 2.54
21 Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet 2012 2.29
22 Wnt signaling and Dupuytren's disease. N Engl J Med 2011 2.02
23 Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet 2012 1.79
24 Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease. Hum Mol Genet 2010 1.78
25 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
26 Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. Am J Hum Genet 2010 1.71
27 Complex nature of SNP genotype effects on gene expression in primary human leucocytes. BMC Med Genomics 2009 1.64
28 MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects. Bioinformatics 2011 1.60
29 Human disease-associated genetic variation impacts large intergenic non-coding RNA expression. PLoS Genet 2013 1.59
30 Blood pressure loci identified with a gene-centric array. Am J Hum Genet 2011 1.44
31 Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet 2012 1.29
32 Gene-network analysis identifies susceptibility genes related to glycobiology in autism. PLoS One 2009 1.23
33 Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. Gut 2013 1.14
34 Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9. Hepatology 2011 1.09
35 Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine model. BMC Med Genomics 2014 1.02
36 Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene. Hum Reprod 2009 1.01
37 Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray study. BMC Med Genomics 2010 0.98
38 Combination of text-mining algorithms increases the performance. Bioinformatics 2006 0.98
39 A strategy to search for common obesity and type 2 diabetes genes. Trends Endocrinol Metab 2006 0.96
40 Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. PLoS One 2012 0.95
41 Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. PLoS Genet 2013 0.93
42 Neutrophil recruitment and barrier impairment in celiac disease: a genomic study. Clin Gastroenterol Hepatol 2007 0.93
43 HHEX gene polymorphisms are associated with type 2 diabetes in the Dutch Breda cohort. Eur J Hum Genet 2008 0.92
44 A genome-wide association study of circulating galectin-3. PLoS One 2012 0.89
45 Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant. Hum Mol Genet 2013 0.89
46 Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration. BMC Res Notes 2014 0.89
47 A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. Hum Mol Genet 2011 0.87
48 DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts. PLoS Genet 2013 0.86
49 Systematic genotype-phenotype analysis of autism susceptibility loci implicates additional symptoms to co-occur with autism. Eur J Hum Genet 2009 0.84
50 Copy number variants on the X chromosome in women with primary ovarian insufficiency. Fertil Steril 2011 0.84
51 No genetic association of the human prolyl endopeptidase gene in the Dutch celiac disease population. Am J Physiol Gastrointest Liver Physiol 2005 0.84
52 Genome-wide analysis shows no genomic predictors of ovarian response to stimulation by exogenous FSH for IVF. Reprod Biomed Online 2010 0.82
53 Proteomic studies related to genetic determinants of variability in protein concentrations. J Proteome Res 2013 0.82
54 Correlation of genetic risk and messenger RNA expression in a Th17/IL23 pathway analysis in inflammatory bowel disease. Inflamm Bowel Dis 2014 0.82
55 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.81
56 Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis. Arthritis Rheum 2010 0.80
57 Extraintestinal manifestations and complications in inflammatory bowel disease: from shared genetics to shared biological pathways. Inflamm Bowel Dis 2014 0.78
58 Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nat Genet 2016 0.77
59 Gene co-expression analysis for functional classification and gene-disease predictions. Brief Bioinform 2017 0.76
60 Corrigendum: Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi. Nat Med 2016 0.76
61 No evidence in a large UK collection for celiac disease risk variants reported by a Spanish study. Gastroenterology 2008 0.75
62 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest 2017 0.75
63 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
64 Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet 2016 0.75
65 Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Sci Transl Med 2022 0.75
66 Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun 2015 0.75