Published in Nat Genet on November 13, 2005
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet (2006) 15.63
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet (2007) 8.50
Celiac disease: pathogenesis of a model immunogenetic disease. J Clin Invest (2007) 2.28
Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis. Gut (2009) 1.65
Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms. PLoS One (2008) 1.64
Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics. Front Immunol (2013) 1.41
Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms. Ann N Y Acad Sci (2009) 1.39
Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness. Am J Respir Crit Care Med (2009) 1.35
Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays. Am J Hum Genet (2008) 1.27
The myosin superfamily at a glance. J Cell Sci (2012) 1.23
Novel immune response to gluten in individuals with schizophrenia. Schizophr Res (2009) 1.16
Growth factor-like activity of gliadin, an alimentary protein: implications for coeliac disease. Gut (2006) 1.12
Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin. PLoS One (2009) 1.06
IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease. BMC Med Genet (2009) 1.06
Pathophysiology of celiac disease. Gastrointest Endosc Clin N Am (2012) 1.05
Review article: coeliac disease, new approaches to therapy. Aliment Pharmacol Ther (2012) 1.04
Inflammatory bowel disease: genetic and epidemiologic considerations. World J Gastroenterol (2008) 1.03
Zonulin, regulation of tight junctions, and autoimmune diseases. Ann N Y Acad Sci (2012) 1.00
MAGI2 genetic variation and inflammatory bowel disease. Inflamm Bowel Dis (2009) 0.93
IBD candidate genes and intestinal barrier regulation. Inflamm Bowel Dis (2014) 0.92
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. Eur J Hum Genet (2009) 0.92
Epithelial junctions and Rho family GTPases: the zonular signalosome. Small GTPases (2014) 0.91
Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease. Clin Exp Immunol (2008) 0.90
Myosins in cell junctions. Bioarchitecture (2012) 0.89
Lack of association of MYO9B genetic variants with coeliac disease in a British cohort. Gut (2006) 0.88
Functional classification of 15 million SNPs detected from diverse chicken populations. DNA Res (2015) 0.87
MYO9B polymorphisms in patients with inflammatory bowel disease. Gut (2007) 0.87
Multiple independent variants in 6q21-22 associated with susceptibility to celiac disease in the Dutch, Finnish and Hungarian populations. Eur J Hum Genet (2011) 0.87
A nationwide study of the association between celiac disease and the risk of autistic spectrum disorders. JAMA Psychiatry (2013) 0.86
Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis. Cytoskeleton (Hoboken) (2014) 0.85
A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation. Mol Biol Cell (2012) 0.85
Gliadin fragments promote migration of dendritic cells. J Cell Mol Med (2011) 0.85
Wheat-related disorders: A broad spectrum of 'evolving' diseases. United European Gastroenterol J (2014) 0.85
The SPINK gene family and celiac disease susceptibility. Immunogenetics (2007) 0.84
Altered gene expression in highly purified enterocytes from patients with active coeliac disease. BMC Genomics (2008) 0.83
Therapeutic approaches for celiac disease. Best Pract Res Clin Gastroenterol (2015) 0.81
Dermatitis herpetiformis: from the genetics to the development of skin lesions. Clin Dev Immunol (2012) 0.80
Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability. Gastroenterol Res Pract (2016) 0.79
Active and passive involvement of claudins in the pathophysiology of intestinal inflammatory diseases. Pflugers Arch (2016) 0.79
Meta-analysis of genome-wide linkage studies in celiac disease. Hum Hered (2009) 0.79
The intestinal epithelial barrier: a therapeutic target? Nat Rev Gastroenterol Hepatol (2016) 0.78
Current and emerging therapy for celiac disease. Front Med (Lausanne) (2014) 0.78
Association analysis of genetic variants in the myosin IXB gene in acute pancreatitis. PLoS One (2013) 0.78
Association of MYO9B gene polymorphisms with inflammatory bowel disease in Chinese Han population. World J Gastroenterol (2014) 0.77
The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity. PLoS One (2014) 0.76
Recent computational approaches to understand gene regulation: mining gene regulation in silico. Curr Genomics (2007) 0.76
MYO9B polymorphisms in multiple sclerosis. Eur J Hum Genet (2009) 0.75
Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon. Sci Rep (2016) 0.75
Zonulin transgenic mice show altered gut permeability and increased morbidity/mortality in the DSS colitis model. Ann N Y Acad Sci (2017) 0.75
MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases. Oncotarget (2016) 0.75
Genetic association analysis of LARS2 with type 2 diabetes. Diabetologia (2009) 0.75
Celiac disease resolution after allogeneic bone marrow transplantation is associated with absence of gliadin-specific memory response by donor-derived intestinal T-cells. J Clin Immunol (2013) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet (2011) 59.36
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet (2003) 53.59
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
The structure of haplotype blocks in the human genome. Science (2002) 50.88
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Genome-wide association studies for common diseases and complex traits. Nat Rev Genet (2005) 33.96
Structure validation by Calpha geometry: phi,psi and Cbeta deviation. Proteins (2003) 32.38
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
The landscape of somatic copy-number alteration across human cancers. Nature (2010) 31.88
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Efficiency and power in genetic association studies. Nat Genet (2005) 25.56
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature (2005) 23.04
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet (2008) 19.55
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet (2008) 15.89
SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics (2008) 15.77
Common deletion polymorphisms in the human genome. Nat Genet (2006) 15.66
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet (2006) 15.63
Genetic mapping in human disease. Science (2008) 15.12
Calibrating a coalescent simulation of human genome sequence variation. Genome Res (2005) 15.04
Evaluating and improving power in whole-genome association studies using fixed marker sets. Nat Genet (2006) 14.76
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Pooled association tests for rare variants in exon-resequencing studies. Am J Hum Genet (2010) 13.18
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
Efficient control of population structure in model organism association mapping. Genetics (2008) 12.32
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet (2008) 12.07
Methods for high-density admixture mapping of disease genes. Am J Hum Genet (2004) 12.02
Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet Epidemiol (2008) 11.28
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet (2010) 9.90
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med (2007) 9.80
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science (2010) 9.61
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet (2008) 9.52
Testing for an unusual distribution of rare variants. PLoS Genet (2011) 9.28
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet (2007) 8.50
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet (2009) 8.39
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med (2006) 7.75
Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med (2008) 7.66
Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet (2008) 7.63
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet (2006) 7.49
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet (2009) 7.16
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
Multiple common variants for celiac disease influencing immune gene expression. Nat Genet (2010) 6.90
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. N Engl J Med (2010) 6.84