Published in Osteoporos Int on June 03, 2009
Lactation is associated with greater maternal bone size and bone strength later in life. Osteoporos Int (2011) 2.19
The role of estrogen and androgen receptors in bone health and disease. Nat Rev Endocrinol (2013) 1.48
Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. J Bone Miner Res (2013) 1.16
Follicle-stimulating hormone increases bone mass in female mice. Proc Natl Acad Sci U S A (2010) 0.98
Hormonal modulation of connective tissue homeostasis and sex differences in risk for osteoarthritis of the knee. Biol Sex Differ (2013) 0.91
Role of direct estrogen receptor signaling in wear particle-induced osteolysis. Biomaterials (2012) 0.89
Functions and physiological roles of two types of estrogen receptors, ERα and ERβ, identified by estrogen receptor knockout mouse. Lab Anim Res (2012) 0.82
Estrogens and Androgens in Skeletal Physiology and Pathophysiology. Physiol Rev (2017) 0.81
The endocrine role of estrogens on human male skeleton. Int J Endocrinol (2015) 0.80
Effects of Deletion of ERα in Osteoblast-Lineage Cells on Bone Mass and Adaptation to Mechanical Loading Differ in Female and Male Mice. J Bone Miner Res (2015) 0.80
Repression of osteoblast maturation by ERRα accounts for bone loss induced by estrogen deficiency. PLoS One (2013) 0.80
Genetic and hormonal control of bone volume, architecture, and remodeling in XXY mice. J Bone Miner Res (2010) 0.78
Estrogen Receptor α Regulates Dlx3-Mediated Osteoblast Differentiation. Mol Cells (2015) 0.76
Psoralen and Isopsoralen Ameliorate Sex Hormone Deficiency-Induced Osteoporosis in Female and Male Mice. Biomed Res Int (2016) 0.76
Low bone mass in microscopic colitis. BMC Gastroenterol (2011) 0.75
Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med (1994) 6.59
Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Proc Natl Acad Sci U S A (1998) 5.86
Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development (2000) 5.03
Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. Cell (2001) 4.78
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell (2007) 4.71
The multifaceted mechanisms of estradiol and estrogen receptor signaling. J Biol Chem (2001) 4.67
Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene. Mol Endocrinol (1995) 3.21
Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc Natl Acad Sci U S A (1998) 3.06
Evidence of estrogen receptors in normal human osteoblast-like cells. Science (1988) 2.85
Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids. J Biol Chem (2007) 2.73
Effect of testosterone and estradiol in a man with aromatase deficiency. N Engl J Med (1997) 2.52
Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice. Mol Endocrinol (2003) 2.38
Estrogen receptors alpha and beta are differentially expressed in developing human bone. J Clin Endocrinol Metab (2001) 2.23
Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERbeta(-/-) mice. J Clin Invest (1999) 2.21
Sex steroids and bone. Recent Prog Horm Res (2002) 2.17
Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-beta in bone remodeling in females but not in males. Bone (2002) 2.13
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice. Endocrinology (2008) 2.09
An estrogen receptor (ER)alpha deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo. Mol Endocrinol (2002) 2.08
Estrogen receptor (ER) beta, a modulator of ERalpha in the uterus. Proc Natl Acad Sci U S A (2000) 1.97
Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J (2008) 1.96
Identification of an estrogen response element activated by metabolites of 17beta-estradiol and raloxifene. Science (1996) 1.95
Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice. Proc Natl Acad Sci U S A (2000) 1.90
Osteoporosis in men. Endocr Rev (2008) 1.80
Suppressive function of androgen receptor in bone resorption. Proc Natl Acad Sci U S A (2003) 1.72
Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. N Engl J Med (1998) 1.71
Estrogen inhibits bone resorption by directly inducing apoptosis of the bone-resorbing osteoclasts. J Exp Med (1997) 1.68
Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. J Biol Chem (1994) 1.62
Clinical review 144: Estrogen and the male skeleton. J Clin Endocrinol Metab (2002) 1.61
Estrogen receptor beta: the antimechanostat? Bone (2005) 1.54
A functional androgen receptor is not sufficient to allow estradiol to protect bone after gonadectomy in estradiol receptor-deficient mice. J Clin Invest (2003) 1.40
Expression of estrogen receptor beta in rat bone. Endocrinology (1997) 1.33
Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha. FASEB J (2008) 1.31
Estrogen receptor specificity in the regulation of the skeleton in female mice. J Endocrinol (2001) 1.31
Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology (2003) 1.28
The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-alpha and -beta. J Endocrinol (2004) 1.23
Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways. J Bone Miner Res (2005) 1.23
Differential contributions of ovarian and extraovarian factors to age-related reductions in plasma estradiol and progesterone during the estrous cycle of C57BL/6J mice. Endocrinology (1992) 1.22
The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice. Am J Physiol Endocrinol Metab (2008) 1.22
Expression and localization of estrogen receptor-beta in murine and human bone. J Bone Miner Res (1999) 1.22
Female estrogen receptor beta-/- mice are partially protected against age-related trabecular bone loss. J Bone Miner Res (2001) 1.20
A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction. J Biol Chem (2007) 1.19
Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model. J Bone Miner Res (2006) 1.17
Estrogens are essential for male pubertal periosteal bone expansion. J Clin Endocrinol Metab (2004) 1.16
Localization of estrogen receptor beta protein expression in adult human bone. J Bone Miner Res (2001) 1.15
Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice. Proc Natl Acad Sci U S A (2003) 1.11
Clinical Review: Sex steroids and the periosteum--reconsidering the roles of androgens and estrogens in periosteal expansion. J Clin Endocrinol Metab (2005) 1.10
Twenty-four-hour profiles of luteinizing hormone, follicle-stimulating hormone, testosterone, and estradiol levels: a semilongitudinal study throughout puberty in healthy boys. J Clin Endocrinol Metab (1997) 1.03
Bone has a sexually dimorphic response to aromatase deficiency. J Bone Miner Res (2000) 1.01
Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice. J Bone Miner Res (2000) 0.99
Sex- and age-related response to aromatase deficiency in bone. Biochem Biophys Res Commun (2001) 0.93
Effects of loss of classical estrogen response element signaling on bone in male mice. Endocrinology (2007) 0.93
Human osteoblasts' proliferative responses to strain and 17beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I. J Bone Miner Res (2002) 0.92
Oestrogen receptors and linear bone growth. Acta Paediatr (2007) 0.92
Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor-alpha-deficient male and female mice. Eur J Endocrinol (2005) 0.91
Mechanical strain activates estrogen response elements in bone cells. Bone (2000) 0.89
Diurnal rhythm of 17 beta-estradiol secretion throughout pubertal development in healthy girls: evaluation by a sensitive radioimmunoassay. J Clin Endocrinol Metab (1996) 0.89
The role of estrogen receptor-beta, in the early age-related bone gain and later age-related bone loss in female mice. J Musculoskelet Neuronal Interact (2002) 0.88
Growth without growth hormone receptor: estradiol is a major growth hormone-independent regulator of hepatic IGF-I synthesis. J Bone Miner Res (2005) 0.88
Estrogen and adiposity--utilizing models of aromatase deficiency to explore the relationship. J Steroid Biochem Mol Biol (2007) 0.87
Oral estradiol administration modulates continuous intravenous growth hormone (GH)-releasing peptide-2-driven GH secretion in postmenopausal women. J Clin Endocrinol Metab (2000) 0.79
Estrogen-induced osteogenesis in intact female mice lacking ERbeta. Am J Physiol Endocrinol Metab (2002) 0.79
Effects of growth hormone and insulinlike growth factor-I on body growth and adult bone metabolism. Curr Opin Rheumatol (2000) 0.75
Estrogen receptor beta: the antimechanostat? Bone (2005) 0.75
Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand. J Mol Endocrinol (2003) 1.48
Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1. Oncogene (2011) 0.96
Dimerization is required for transactivation by estrogen-receptor-related (ERR) orphan receptors: evidence from amphioxus ERR. J Mol Endocrinol (2004) 0.92
Characterization of oestrogen receptors in zebrafish (Danio rerio). J Mol Endocrinol (2002) 0.91
Expression of the orphan nuclear receptor ERRalpha is under circadian regulation in estrogen-responsive tissues. J Mol Endocrinol (2004) 0.91