Published in Clin Cancer Res on June 09, 2009
SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis. Oncogene (2012) 1.70
The emerging and diverse roles of sirtuins in cancer: a clinical perspective. Onco Targets Ther (2013) 1.57
Sorting out functions of sirtuins in cancer. Oncogene (2013) 1.47
Janus-faced role of SIRT1 in tumorigenesis. Ann N Y Acad Sci (2012) 1.43
SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability. PLoS Genet (2011) 1.41
Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients. Oncotarget (2016) 1.40
Identification of DBC1 as a transcriptional repressor for BRCA1. Br J Cancer (2010) 1.31
SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas. PLoS One (2012) 1.13
Expression of SIRT1 and DBC1 is associated with poor prognosis of soft tissue sarcomas. PLoS One (2013) 1.01
Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors. Cell Mol Life Sci (2010) 1.00
SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells. Prostate (2012) 1.00
DBC1 is over-expressed and associated with poor prognosis in colorectal cancer. Int J Clin Oncol (2013) 0.99
Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer. Biosci Rep (2013) 0.98
Enterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model. PLoS One (2013) 0.98
Expression of SIRT1 and DBC1 in Gastric Adenocarcinoma. Korean J Pathol (2012) 0.96
Low SIRT3 expression correlates with poor differentiation and unfavorable prognosis in primary hepatocellular carcinoma. PLoS One (2012) 0.96
SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer. Korean J Pathol (2013) 0.96
DBC1 functions as a tumor suppressor by regulating p53 stability. Cell Rep (2015) 0.95
RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response. Int J Genomics (2013) 0.95
SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer. Cancer Med (2014) 0.93
SIRT1 is highly expressed in brain metastasis tissues of non-small cell lung cancer (NSCLC) and in positive regulation of NSCLC cell migration. Int J Clin Exp Pathol (2013) 0.92
Sirt7 promotes gastric cancer growth and inhibits apoptosis by epigenetically inhibiting miR-34a. Sci Rep (2015) 0.92
DBC1 does not function as a negative regulator of SIRT1 in liver cancer. Oncol Lett (2012) 0.91
Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer. Exp Ther Med (2011) 0.91
Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancer. J Exp Clin Cancer Res (2014) 0.91
Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis. Cancer Prev Res (Phila) (2012) 0.90
Sirtuin-3 (SIRT3) and the Hallmarks of Cancer. Genes Cancer (2013) 0.88
Diverse roles of SIRT1 in cancer biology and lipid metabolism. Int J Mol Sci (2015) 0.88
The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas. PLoS One (2013) 0.88
Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis. Nucleic Acids Res (2014) 0.88
Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation. PLoS One (2014) 0.88
Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis. Mol Cancer (2014) 0.87
Expression of SIRT1 and DBC1 in Developing and Adult Retinas. Stem Cells Int (2012) 0.86
SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression. Mol Endocrinol (2013) 0.86
Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-κB. Mol Nutr Food Res (2011) 0.86
A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription. J Proteomics Bioinform (2013) 0.86
The expression and correlation of SIRT1 and Phospho-SIRT1 in colorectal cancer. Int J Clin Exp Med (2015) 0.84
Expression of DBC1 and Androgen Receptor Predict Poor Prognosis in Diffuse Large B Cell Lymphoma. Transl Oncol (2013) 0.84
SIRT1 expression is associated with poor prognosis of lung adenocarcinoma. Onco Targets Ther (2015) 0.84
Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction. Oncotarget (2015) 0.83
DBC1/CCAR2 is involved in the stabilization of androgen receptor and the progression of osteosarcoma. Sci Rep (2015) 0.82
Nicotinamide-mediated inhibition of SIRT1 deacetylase is associated with the viability of cancer cells exposed to antitumor agents and apoptosis. Oncol Lett (2013) 0.82
Clinicopathological and prognostic role of SIRT1 in breast cancer patients: a meta-analysis. Int J Clin Exp Med (2015) 0.81
The expression of DBC1/CCAR2 is associated with poor prognosis of ovarian carcinoma. J Ovarian Res (2015) 0.81
Frizzled 7 expression is positively regulated by SIRT1 and β-catenin in breast cancer cells. PLoS One (2014) 0.81
Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications. Oncotarget (2015) 0.81
Association of SIRT1 and HMGA1 expression in non-small cell lung cancer. Oncol Lett (2015) 0.78
High DBC1 (CCAR2) expression in gallbladder carcinoma is associated with favorable clinicopathological factors. Int J Clin Exp Pathol (2015) 0.77
Deleted in Breast Cancer 1 Suppresses B Cell Activation through RelB and Is Regulated by IKKα Phosphorylation. J Immunol (2015) 0.77
Association between SIRT1 Gene Polymorphisms and Breast Cancer in Egyptians. PLoS One (2016) 0.76
Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities. Int J Oncol (2014) 0.76
High-Throughput Sequencing of miRNAs Reveals a Tissue Signature in Gastric Cancer and Suggests Novel Potential Biomarkers. Bioinform Biol Insights (2015) 0.76
SIRT1 expression is associated with lymphangiogenesis, lymphovascular invasion and prognosis in pN0 esophageal squamous cell carcinoma. Cell Biosci (2014) 0.76
CCAR2 Is Required for Proliferation and Tumor Maintenance in Human Squamous Cell Carcinoma. J Invest Dermatol (2016) 0.75
Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1. Oncotarget (2016) 0.75
High glucose promotes gastric cancer chemoresistance in vivo and in vitro. Mol Med Rep (2015) 0.75
The Prognostic Role of SIRT1-Autophagy Axis in Gastric Cancer. Dis Markers (2016) 0.75
Co-ordinated overexpression of SIRT1 and STAT3 is associated with poor survival outcome in gastric cancer patients. Oncotarget (2017) 0.75
Association of FGFR2 rs2981582, SIRT1 rs12778366, STAT3 rs744166 gene polymorphisms with pituitary adenoma. Oncol Lett (2017) 0.75
Meta-analysis of SIRT1 expression as a prognostic marker for overall survival in gastrointestinal cancer. Oncotarget (2017) 0.75
The prognostic role of Sirt1 expression in solid malignancies: a meta-analysis. Oncotarget (2017) 0.75
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
Making insulin-deficient type 1 diabetic rodents thrive without insulin. Proc Natl Acad Sci U S A (2008) 2.12
Rapid transformation of white adipocytes into fat-oxidizing machines. Proc Natl Acad Sci U S A (2004) 2.03
Multiple gastrointestinal stromal tumors: Clinicopathologic and genetic analysis of 12 patients. Am J Surg Pathol (2007) 2.02
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway. Diabetes (2008) 2.00
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex. Nat Cell Biol (2004) 1.99
Telomerase regulation of myofibroblast differentiation. Am J Respir Cell Mol Biol (2006) 1.84
Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma. Hum Pathol (2010) 1.76
Current Trends of the Incidence and Pathological Diagnosis of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) in Korea 2000-2009: Multicenter Study. Cancer Res Treat (2012) 1.76
COMP-angiopoietin-1 ameliorates renal fibrosis in a unilateral ureteral obstruction model. J Am Soc Nephrol (2006) 1.74
Interstitial lung abnormalities in a CT lung cancer screening population: prevalence and progression rate. Radiology (2013) 1.72
Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis. Leuk Lymphoma (2008) 1.68
Negative regulation of hypoxic responses via induced Reptin methylation. Mol Cell (2010) 1.68
Roles of Mis18α in epigenetic regulation of centromeric chromatin and CENP-A loading. Mol Cell (2012) 1.59
O-GlcNAcase is essential for embryonic development and maintenance of genomic stability. Aging Cell (2012) 1.49
ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter. J Biol Chem (2005) 1.48
Overexpression of VEGF and angiopoietin 2: a key to high vascularity of hepatocellular carcinoma? Mod Pathol (2003) 1.45
Angiomyofibroblastoma of the vagina in a breast cancer patient. Pathology (2008) 1.45
SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma. Am J Surg Pathol (2008) 1.43
cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes. EMBO J (2013) 1.42
Hydrogen storage in ni nanoparticle-dispersed multiwalled carbon nanotubes. J Phys Chem B (2005) 1.39
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice. J Clin Invest (2007) 1.36
Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b+ macrophages in advanced ovarian cancer. Cancer Res (2008) 1.30
Expression and prognostic significance of SIRT1 in ovarian epithelial tumours. Pathology (2009) 1.29
Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin. Diabetes (2007) 1.26
Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway. Toxicol Appl Pharmacol (2008) 1.26
Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases. Hum Pathol (2010) 1.22
The centrosomal protein RAS association domain family protein 1A (RASSF1A)-binding protein 1 regulates mitotic progression by recruiting RASSF1A to spindle poles. J Biol Chem (2004) 1.21
Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. Proc Natl Acad Sci U S A (2004) 1.21
Diagnosis of gastric epithelial neoplasia: Dilemma for Korean pathologists. World J Gastroenterol (2011) 1.20
Gastrointestinal stromal tumors in Koreans: it's incidence and the clinical, pathologic and immunohistochemical findings. J Korean Med Sci (2005) 1.20
Wnt-β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice. Gastroenterology (2011) 1.19
Retropharyngeal spindle cell/pleomorphic lipoma. Korean J Radiol (2013) 1.15
Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Mol Cancer Res (2003) 1.15
Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme. Biochem Pharmacol (2008) 1.14
SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas. PLoS One (2012) 1.13
Expression of the serum response factor in hepatocellular carcinoma: implications for epithelial-mesenchymal transition. Int J Oncol (2007) 1.13
Gastric collision tumor of large cell neuroendocrine carcinoma and adenocarcinoma--a case report. Pathol Res Pract (2009) 1.11
Induction of apoptosis by diallyl disulfide through activation of caspase-3 in human leukemia HL-60 cells. Biochem Pharmacol (2002) 1.11
Estimation of standard liver volume for liver transplantation in the Korean population. Liver Transpl (2004) 1.10
Ileal angiomyolipoma manifested by small intestinal intussusception. World J Gastroenterol (2009) 1.08
Torsion of a mucocele of the vermiform appendix: a case report and review of the literature. J Korean Surg Soc (2011) 1.08
Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels. Pharmacol Res (2009) 1.08
A20 suppresses inflammatory responses and bone destruction in human fibroblast-like synoviocytes and in mice with collagen-induced arthritis. Arthritis Rheum (2010) 1.08
Tumor-infiltrating PD1-Positive Lymphocytes and FoxP3-Positive Regulatory T Cells Predict Distant Metastatic Relapse and Survival of Clear Cell Renal Cell Carcinoma. Transl Oncol (2013) 1.08
Expression of MUC1, MUC2, MUC5AC and MUC6 in cholangiocarcinoma: prognostic impact. Oncol Rep (2009) 1.08
Prospective randomized controlled trial (phase III) to comparing laparoscopic distal gastrectomy with open distal gastrectomy for gastric adenocarcinoma (KLASS 01). J Korean Surg Soc (2013) 1.08
Current trends in the epidemiological and pathological characteristics of gastrointestinal stromal tumors in Korea, 2003-2004. J Korean Med Sci (2010) 1.08
Alpha-lipoic acid prevents lipotoxic cardiomyopathy in acyl CoA-synthase transgenic mice. Biochem Biophys Res Commun (2006) 1.07
Rosiglitazone ameliorates cisplatin-induced renal injury in mice. Nephrol Dial Transplant (2006) 1.07
Pulmonary benign metastasizing leiomyoma in a postmenopausal woman. Am J Med Sci (2009) 1.06
COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury. Kidney Int (2009) 1.05
Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts. Am J Respir Cell Mol Biol (2011) 1.05