Published in Hum Pathol on November 05, 2010
SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis. Oncogene (2012) 1.70
The emerging and diverse roles of sirtuins in cancer: a clinical perspective. Onco Targets Ther (2013) 1.57
The dual role of sirtuins in cancer. Genes Cancer (2011) 1.45
SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas. PLoS One (2012) 1.13
Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy. Nucleic Acids Res (2011) 1.09
Expression of SIRT1 and DBC1 is associated with poor prognosis of soft tissue sarcomas. PLoS One (2013) 1.01
Derailed estrogen signaling and breast cancer: an authentic couple. Endocr Rev (2012) 1.01
SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells. Prostate (2012) 1.00
DBC1 is over-expressed and associated with poor prognosis in colorectal cancer. Int J Clin Oncol (2013) 0.99
High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients. BMC Cancer (2014) 0.98
Enterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model. PLoS One (2013) 0.98
SIRT1 expression is associated with the chemotherapy response and prognosis of patients with advanced NSCLC. PLoS One (2013) 0.98
Expression of SIRT1 and DBC1 in Gastric Adenocarcinoma. Korean J Pathol (2012) 0.96
SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer. Korean J Pathol (2013) 0.96
SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer. Cancer Med (2014) 0.93
DBC1 does not function as a negative regulator of SIRT1 in liver cancer. Oncol Lett (2012) 0.91
Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancer. J Exp Clin Cancer Res (2014) 0.91
Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer. Exp Ther Med (2011) 0.91
Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-κB. Apoptosis (2013) 0.91
Sirtuin 1 (SIRT1) and steroid hormone receptor activity in cancer. J Endocrinol (2011) 0.91
Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis. Cancer Prev Res (Phila) (2012) 0.90
Diverse roles of SIRT1 in cancer biology and lipid metabolism. Int J Mol Sci (2015) 0.88
Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis. Nucleic Acids Res (2014) 0.88
The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration. Oncogene (2013) 0.88
Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach. Oncotarget (2014) 0.87
Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis. Mol Cancer (2014) 0.87
Class III-specific HDAC inhibitor Tenovin-6 induces apoptosis, suppresses migration and eliminates cancer stem cells in uveal melanoma. Sci Rep (2016) 0.86
SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression. Mol Endocrinol (2013) 0.86
A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription. J Proteomics Bioinform (2013) 0.86
Expression of sirtuin 1 and 2 is associated with poor prognosis in non-small cell lung cancer patients. PLoS One (2015) 0.86
Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target. Lab Invest (2015) 0.84
Retracted Regulation of estrogen receptor signaling in breast carcinogenesis and breast cancer therapy. Cell Mol Life Sci (2014) 0.84
SIRT1 expression is associated with poor prognosis of lung adenocarcinoma. Onco Targets Ther (2015) 0.84
Expression of DBC1 and Androgen Receptor Predict Poor Prognosis in Diffuse Large B Cell Lymphoma. Transl Oncol (2013) 0.84
SIRT1 catalytic activity has little effect on tumor formation and metastases in a mouse model of breast cancer. PLoS One (2013) 0.84
A positive role of DBC1 in PEA3-mediated progression of estrogen receptor-negative breast cancer. Oncogene (2014) 0.83
DBC1/CCAR2 is involved in the stabilization of androgen receptor and the progression of osteosarcoma. Sci Rep (2015) 0.82
Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity. Open Biol (2013) 0.82
SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth. Cell Death Dis (2014) 0.81
Clinicopathological and prognostic role of SIRT1 in breast cancer patients: a meta-analysis. Int J Clin Exp Med (2015) 0.81
The expression of DBC1/CCAR2 is associated with poor prognosis of ovarian carcinoma. J Ovarian Res (2015) 0.81
Potential Modulation of Sirtuins by Oxidative Stress. Oxid Med Cell Longev (2015) 0.81
Frizzled 7 expression is positively regulated by SIRT1 and β-catenin in breast cancer cells. PLoS One (2014) 0.81
CARP-1/CCAR1: a biphasic regulator of cancer cell growth and apoptosis. Oncotarget (2015) 0.80
Genetic variation in SIRT1 affects susceptibility of lung squamous cell carcinomas in former uranium miners from the Colorado plateau. Carcinogenesis (2013) 0.80
rhEPO affects apoptosis in hippocampus of aging rats by upregulating SIRT1. Int J Clin Exp Pathol (2015) 0.80
Association of SIRT1 and HMGA1 expression in non-small cell lung cancer. Oncol Lett (2015) 0.78
Expression of FOXM1 and related proteins in breast cancer molecular subtypes. Int J Exp Pathol (2016) 0.78
High DBC1 (CCAR2) expression in gallbladder carcinoma is associated with favorable clinicopathological factors. Int J Clin Exp Pathol (2015) 0.77
Oncogenic role of SIRT1 associated with tumor invasion, lymph node metastasis, and poor disease-free survival in triple negative breast cancer. Clin Exp Metastasis (2015) 0.76
Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer. Virchows Arch (2015) 0.76
Association between SIRT1 Gene Polymorphisms and Breast Cancer in Egyptians. PLoS One (2016) 0.76
Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities. Int J Oncol (2014) 0.76
Functional characterization of NAD dependent de-acetylases SIRT1 and SIRT2 in B-Cell Chronic Lymphocytic Leukemia (CLL). Cancer Biol Ther (2016) 0.75
Modulation of tumorigenesis by dietary intervention is not mediated by SIRT1 catalytic activity. PLoS One (2014) 0.75
Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1. Oncotarget (2016) 0.75
Co-ordinated overexpression of SIRT1 and STAT3 is associated with poor survival outcome in gastric cancer patients. Oncotarget (2017) 0.75
SIRT1 controls cell proliferation by regulating contact inhibition. Biochem Biophys Res Commun (2016) 0.75
The prognostic role of Sirt1 expression in solid malignancies: a meta-analysis. Oncotarget (2017) 0.75
Making insulin-deficient type 1 diabetic rodents thrive without insulin. Proc Natl Acad Sci U S A (2008) 2.12
Rapid transformation of white adipocytes into fat-oxidizing machines. Proc Natl Acad Sci U S A (2004) 2.03
Multiple gastrointestinal stromal tumors: Clinicopathologic and genetic analysis of 12 patients. Am J Surg Pathol (2007) 2.02
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway. Diabetes (2008) 2.00
Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Clin Cancer Res (2009) 1.87
Telomerase regulation of myofibroblast differentiation. Am J Respir Cell Mol Biol (2006) 1.84
Current Trends of the Incidence and Pathological Diagnosis of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) in Korea 2000-2009: Multicenter Study. Cancer Res Treat (2012) 1.76
COMP-angiopoietin-1 ameliorates renal fibrosis in a unilateral ureteral obstruction model. J Am Soc Nephrol (2006) 1.74
Interstitial lung abnormalities in a CT lung cancer screening population: prevalence and progression rate. Radiology (2013) 1.72
Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis. Leuk Lymphoma (2008) 1.68
ERK1/2-dependent activation of transcription factors required for acute and chronic effects of glucose on the insulin gene promoter. J Biol Chem (2005) 1.48
SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma. Am J Surg Pathol (2008) 1.43
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice. J Clin Invest (2007) 1.36
Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b+ macrophages in advanced ovarian cancer. Cancer Res (2008) 1.30
Expression and prognostic significance of SIRT1 in ovarian epithelial tumours. Pathology (2009) 1.29
Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin. Diabetes (2007) 1.26
Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway. Toxicol Appl Pharmacol (2008) 1.26
Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases. Hum Pathol (2010) 1.22
Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. Proc Natl Acad Sci U S A (2004) 1.21
Diagnosis of gastric epithelial neoplasia: Dilemma for Korean pathologists. World J Gastroenterol (2011) 1.20
Gastrointestinal stromal tumors in Koreans: it's incidence and the clinical, pathologic and immunohistochemical findings. J Korean Med Sci (2005) 1.20
Wnt-β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice. Gastroenterology (2011) 1.19
Retropharyngeal spindle cell/pleomorphic lipoma. Korean J Radiol (2013) 1.15
Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme. Biochem Pharmacol (2008) 1.14
SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas. PLoS One (2012) 1.13
Expression of the serum response factor in hepatocellular carcinoma: implications for epithelial-mesenchymal transition. Int J Oncol (2007) 1.13
Gastric collision tumor of large cell neuroendocrine carcinoma and adenocarcinoma--a case report. Pathol Res Pract (2009) 1.11
Induction of apoptosis by diallyl disulfide through activation of caspase-3 in human leukemia HL-60 cells. Biochem Pharmacol (2002) 1.11
Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels. Pharmacol Res (2009) 1.08
A20 suppresses inflammatory responses and bone destruction in human fibroblast-like synoviocytes and in mice with collagen-induced arthritis. Arthritis Rheum (2010) 1.08
Tumor-infiltrating PD1-Positive Lymphocytes and FoxP3-Positive Regulatory T Cells Predict Distant Metastatic Relapse and Survival of Clear Cell Renal Cell Carcinoma. Transl Oncol (2013) 1.08
Expression of MUC1, MUC2, MUC5AC and MUC6 in cholangiocarcinoma: prognostic impact. Oncol Rep (2009) 1.08
Current trends in the epidemiological and pathological characteristics of gastrointestinal stromal tumors in Korea, 2003-2004. J Korean Med Sci (2010) 1.08
Alpha-lipoic acid prevents lipotoxic cardiomyopathy in acyl CoA-synthase transgenic mice. Biochem Biophys Res Commun (2006) 1.07
Rosiglitazone ameliorates cisplatin-induced renal injury in mice. Nephrol Dial Transplant (2006) 1.07
Pulmonary benign metastasizing leiomyoma in a postmenopausal woman. Am J Med Sci (2009) 1.06
COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury. Kidney Int (2009) 1.05
Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts. Am J Respir Cell Mol Biol (2011) 1.05
PKCtheta expression in gastrointestinal stromal tumor. Mod Pathol (2006) 1.05
Overexpression of discoidin domain receptor 1 increases the migration and invasion of hepatocellular carcinoma cells in association with matrix metalloproteinase. Oncol Rep (2007) 1.05
Alpha-lipoic acid attenuates cisplatin-induced acute kidney injury in mice by suppressing renal inflammation. Nephrol Dial Transplant (2009) 1.04
Effects of delay in the snap freezing of colorectal cancer tissues on the quality of DNA and RNA. J Korean Soc Coloproctol (2010) 1.03
Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung carcinomas. Oncol Rep (2010) 1.03
Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/beta-catenin complex. Oncol Rep (2009) 1.02
Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells. Biochem Biophys Res Commun (2005) 1.02
Genistein protects pancreatic beta cells against cytokine-mediated toxicity. Mol Cell Endocrinol (2007) 1.01
Expression of SIRT1 and DBC1 is associated with poor prognosis of soft tissue sarcomas. PLoS One (2013) 1.01
Clear cell "sugar" tumor of the lung: a well-enhanced mass with an early washout pattern on dynamic contrast-enhanced computed tomography. J Korean Med Sci (2008) 1.01
Benign intercostal schwannoma mimicking a solitary metastasis from lung cancer. Thorax (2010) 1.01