Published in BMC Biochem on June 11, 2009
Identification of anziaic acid, a lichen depside from Hypotrachyna sp., as a new topoisomerase poison inhibitor. PLoS One (2013) 0.86
The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites. BMC Biochem (2010) 0.85
3,4-dimethoxyphenyl bis-benzimidazole, a novel DNA topoisomerase inhibitor that preferentially targets Escherichia coli topoisomerase I. J Antimicrob Chemother (2012) 0.85
A surface plasmon resonance study of the intermolecular interaction between Escherichia coli topoisomerase I and pBAD/Thio supercoiled plasmid DNA. Biochem Biophys Res Commun (2014) 0.83
Residues of E. coli topoisomerase I conserved for interaction with a specific cytosine base to facilitate DNA cleavage. Nucleic Acids Res (2012) 0.83
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Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I. Gene (2013) 0.78
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Inhibition of Zn(II) binding type IA topoisomerases by organomercury compounds and Hg(II). PLoS One (2015) 0.75
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Inhibition of Mg2+ binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region. Nucleic Acids Res (2008) 1.05
The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I. BMC Biochem (2002) 1.02
RNase HI overproduction is required for efficient full-length RNA synthesis in the absence of topoisomerase I in Escherichia coli. Mol Microbiol (2004) 0.98
Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I. Nucleic Acids Res (2007) 0.96
Hydroxyl radicals are involved in cell killing by the bacterial topoisomerase I cleavage complex. J Bacteriol (2009) 0.94
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Experimental and computational investigations of Ser10 and Lys13 in the binding and cleavage of DNA substrates by Escherichia coli DNA topoisomerase I. Nucleic Acids Res (2006) 0.93
Isolation and quantitation of topoisomerase complexes accumulated on Escherichia coli chromosomal DNA. Antimicrob Agents Chemother (2012) 0.90
SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway. J Bacteriol (2008) 0.90
The strictly conserved Arg-321 residue in the active site of Escherichia coli topoisomerase I plays a critical role in DNA rejoining. J Biol Chem (2011) 0.87
RNase H overproduction allows the expression of stress-induced genes in the absence of topoisomerase I. FEMS Microbiol Lett (2003) 0.87
Identification of anziaic acid, a lichen depside from Hypotrachyna sp., as a new topoisomerase poison inhibitor. PLoS One (2013) 0.86
Loss of topoisomerase I function affects the RpoS-dependent and GAD systems of acid resistance in Escherichia coli. Microbiology (2005) 0.85
The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites. BMC Biochem (2010) 0.85
Flexibility at Gly-194 is required for DNA cleavage and relaxation activity of Escherichia coli DNA topoisomerase I. J Biol Chem (2004) 0.85
3,4-dimethoxyphenyl bis-benzimidazole, a novel DNA topoisomerase inhibitor that preferentially targets Escherichia coli topoisomerase I. J Antimicrob Chemother (2012) 0.85
Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila. Dis Model Mech (2013) 0.84
Topoisomerase I function during Escherichia coli response to antibiotics and stress enhances cell killing from stabilization of its cleavage complex. J Antimicrob Chemother (2011) 0.84
Residues of E. coli topoisomerase I conserved for interaction with a specific cytosine base to facilitate DNA cleavage. Nucleic Acids Res (2012) 0.83
Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. Bioorg Med Chem Lett (2011) 0.81
SbcCD-mediated processing of covalent gyrase-DNA complex in Escherichia coli. Antimicrob Agents Chemother (2013) 0.78
Analysis of RuvABC and RecG involvement in the escherichia coli response to the covalent topoisomerase-DNA complex. J Bacteriol (2010) 0.78
Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I. Gene (2013) 0.78
[Serological investigations on patients with hemolytic uremic syndromes due to enterohemorrhagic Escherichia coli O157:H7 infection]. Zhonghua Liu Xing Bing Xue Za Zhi (2002) 0.77
Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. J Med Chem (2014) 0.77
Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR. BMC Microbiol (2011) 0.76
Changes in lipid distribution in E. coli strains in response to norfloxacin. J Mass Spectrom (2015) 0.76