Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMC 2755924)

Published in J Biol Chem on June 12, 2009

Authors

Shengli Xu1, Jianxin Huo, Merry Gunawan, I-Hsin Su, Kong-Peng Lam

Author Affiliations

1: Laboratory of Immunology, Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668. xu_shengli@bti.a-star.edu.sg

Articles citing this

Signaling by myeloid C-type lectin receptors in immunity and homeostasis. Annu Rev Immunol (2012) 1.95

Innate immune pattern recognition: a cell biological perspective. Annu Rev Immunol (2015) 1.66

Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome. Microbes Infect (2010) 1.06

Endocytosis of gene delivery vectors: from clathrin-dependent to lipid raft-mediated endocytosis. Mol Ther (2013) 1.03

Cholesterol-rich lipid rafts are required for release of infectious human respiratory syncytial virus particles. Virology (2011) 0.96

Inhibitory C-type lectin receptors in myeloid cells. Immunol Lett (2010) 0.94

Streptococcus suis capsular polysaccharide inhibits phagocytosis through destabilization of lipid microdomains and prevents lactosylceramide-dependent recognition. Infect Immun (2011) 0.91

Immunomodulation of Fungal β-Glucan in Host Defense Signaling by Dectin-1. Biomol Ther (Seoul) (2012) 0.90

Location, location, location: is membrane partitioning everything when it comes to innate immune activation? Mediators Inflamm (2011) 0.86

Galectin-3 modulates Th17 responses by regulating dendritic cell cytokines. Am J Pathol (2013) 0.85

Role of lipid rafts in liver health and disease. World J Gastroenterol (2011) 0.83

Oxidized LDLs inhibit TLR-induced IL-10 production by monocytes: a new aspect of pathogen-accelerated atherosclerosis. Inflammation (2012) 0.82

Clustering of pattern recognition receptors for fungal detection. PLoS Pathog (2014) 0.80

Taenia taeniaeformis in rat favors protracted skin lesions caused by Sporothrix schenckii infection: Dectin-1 and IL-17 are dispensable for clearance of this fungus. PLoS One (2012) 0.79

Activation of the NLRP3 inflammasome by vault nanoparticles expressing a chlamydial epitope. Vaccine (2014) 0.78

Plasma membrane lipids and their role in fungal virulence. Prog Lipid Res (2015) 0.78

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans. PLoS Pathog (2015) 0.77

CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway. PLoS Pathog (2015) 0.76

Fungus induces the release of IL-8 in human corneal epithelial cells, via Dectin-1-mediated protein kinase C pathways. Int J Ophthalmol (2015) 0.76

Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen Specific T Cell Responses. PLoS One (2015) 0.75

Plasma membrane Toll-like receptor activation increases bacterial uptake but abrogates endosomal Lactobacillus acidophilus induction of interferon-β. Immunology (2016) 0.75

Articles cited by this

Functional rafts in cell membranes. Nature (1997) 38.89

Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol (1998) 14.83

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol (2007) 8.92

Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med (2003) 7.38

Immune recognition. A new receptor for beta-glucans. Nature (2001) 6.54

Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol (2006) 6.36

Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity (2005) 6.21

Dectin-1 mediates the biological effects of beta-glucans. J Exp Med (2003) 5.82

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature (2006) 5.34

Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med (2002) 4.87

Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood (2005) 3.57

Membrane microdomains and caveolae. Curr Opin Cell Biol (1999) 3.34

Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting. J Biol Chem (2006) 2.90

Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood (2004) 2.84

Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. J Biol Chem (2000) 2.83

Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med (2006) 2.77

Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol. Mol Biol Cell (1997) 1.84

TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells. J Clin Invest (2004) 1.70

Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan. Eur J Immunol (2007) 1.69

Lipid rafts and B-cell activation. Nat Rev Immunol (2002) 1.68

Visualizing lipid raft dynamics and early signaling events during antigen receptor-mediated B-lymphocyte activation. Mol Biol Cell (2003) 1.66

Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex. Immunity (2000) 1.51

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells. J Biol Chem (2009) 1.38

Lipid rafts and B cell signaling. Semin Cell Dev Biol (2007) 1.29

Cholesterol-dependent clustering of IL-2Ralpha and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts. Proc Natl Acad Sci U S A (2000) 1.27

Colocalization of the IL-12 receptor and FcgammaRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-gamma. Blood (2008) 1.26

IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells. Proc Natl Acad Sci U S A (2004) 1.25

Lipid rafts and the initiation of T cell receptor signaling. Semin Immunol (2005) 1.14

Fc gamma RIIB1/SHIP-mediated inhibitory signaling in B cells involves lipid rafts. J Biol Chem (2001) 1.06

Lipid phosphatases in the regulation of T cell activation: living up to their PTEN-tial. Immunol Rev (2003) 1.04

Lipid rafts orchestrate signaling by the platelet receptor glycoprotein VI. J Biol Chem (2002) 1.02

Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development. Mol Cell Biol (2005) 1.02

IgA Fc receptor (FcalphaR) cross-linking recruits tyrosine kinases, phosphoinositide kinases and serine/threonine kinases to glycolipid rafts. Biochem J (2002) 0.92

Articles by these authors

TACI and BAFF-R mediate isotype switching in B cells. J Exp Med (2005) 3.31

Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development (2003) 2.91

Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J Immunol (2008) 2.38

B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity (2007) 2.28

Macrophage polarization to a unique phenotype driven by B cells. Eur J Immunol (2010) 2.25

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nat Immunol (2003) 2.04

ICOS controls the pool size of effector-memory and regulatory T cells. J Immunol (2008) 1.62

RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection. PLoS Negl Trop Dis (2011) 1.50

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells. PLoS Biol (2005) 1.47

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells. J Biol Chem (2009) 1.38

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response. Proc Natl Acad Sci U S A (2012) 1.22

Peritoneal CD5+ B-1 cells have signaling properties similar to tolerant B cells. J Biol Chem (2002) 1.19

BAFF costimulation of Toll-like receptor-activated B-1 cells. Eur J Immunol (2006) 1.16

The RNase III enzyme Dicer is essential for germinal center B-cell formation. Blood (2011) 1.10

The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs. FEBS J (2010) 1.06

Impaired germinal center formation and recall T-cell-dependent immune responses in mice lacking the costimulatory ligand B7-H2. Blood (2003) 1.05

Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells. Diabetes (2011) 1.04

Bruton's tyrosine kinase separately regulates NFkappaB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B Cells. J Biol Chem (2008) 1.02

Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development. Mol Cell Biol (2005) 1.02

A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming. Stem Cells (2013) 1.01

Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells. J Biol Chem (2006) 0.99

Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells. J Allergy Clin Immunol (2009) 0.98

Deficiency in TNFRSF13B (TACI) expands T-follicular helper and germinal center B cells via increased ICOS-ligand expression but impairs plasma cell survival. Proc Natl Acad Sci U S A (2012) 0.95

Leupaxin negatively regulates B cell receptor signaling. J Biol Chem (2007) 0.95

Pharmacologic inhibition of MEK-ERK signaling enhances Th17 differentiation. J Immunol (2010) 0.93

Dok-3 plays a nonredundant role in negative regulation of B-cell activation. Blood (2007) 0.91

Combined deficiencies in Bruton tyrosine kinase and phospholipase Cgamma2 arrest B-cell development at a pre-BCR+ stage. Blood (2006) 0.90

Comprehensive analysis of CD4+ T cells in the decision between tolerance and immunity in vivo reveals a pivotal role for ICOS. J Immunol (2012) 0.84

Fas apoptosis inhibitory molecule regulates T cell receptor-mediated apoptosis of thymocytes by modulating Akt activation and Nur77 expression. J Biol Chem (2010) 0.82

Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo. Int Immunol (2005) 0.80

Delayed cellular maturation and decreased immunoglobulin kappa light chain production in immature B lymphocytes lacking B cell linker protein. J Exp Med (2002) 0.80

T helper cell-specific regulation of inducible costimulator expression via distinct mechanisms mediated by T-bet and GATA-3. J Biol Chem (2007) 0.79

Functional hierarchy and relative contribution of the CD28/B7 and ICOS/B7-H2 costimulatory pathways to T cell-mediated delayed-type hypersensitivity. Cell Immunol (2009) 0.78

Phospholipase Cgamma2 dosage is critical for B cell development in the absence of adaptor protein BLNK. J Immunol (2006) 0.78

Proteomic analysis of the SH2 domain-containing leukocyte protein of 76 kDa (SLP76) interactome in resting and activated primary mast cells [corrected]. Mol Cell Proteomics (2013) 0.77

Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation. Eur J Med Chem (2011) 0.76

Computer-aided drug design for AMP-activated protein kinase activators. Curr Comput Aided Drug Des (2011) 0.76

Integrative analysis workflow for the structural and functional classification of C-type lectins. BMC Bioinformatics (2011) 0.75

Population of Monocyte-Derived Macrophages. Immunity (2015) 0.75