Published in J Biol Chem on October 31, 2002
International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev (2006) 5.28
Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu Rev Physiol (2010) 3.38
Purinergic signalling in neuron-glia interactions. Nat Rev Neurosci (2006) 3.17
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J Neurosci (2006) 3.14
Identification of a vesicular nucleotide transporter. Proc Natl Acad Sci U S A (2008) 2.53
Connexin 43 hemichannels are permeable to ATP. J Neurosci (2008) 2.46
Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes. J Cell Physiol (2007) 2.24
Astrocyte calcium waves: what they are and what they do. Glia (2006) 2.17
Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine. Proc Natl Acad Sci U S A (2005) 2.06
ATP release from non-excitable cells. Purinergic Signal (2009) 1.78
TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP. Pflugers Arch (2009) 1.75
Intracellular calcium changes trigger connexin 32 hemichannel opening. EMBO J (2005) 1.69
Gliotransmission: Exocytotic release from astrocytes. Brain Res Rev (2009) 1.68
The TRPV4 cation channel mediates stretch-evoked Ca2+ influx and ATP release in primary urothelial cell cultures. J Biol Chem (2009) 1.61
Astrocyte-mediated distributed plasticity at hypothalamic glutamate synapses. Neuron (2009) 1.61
Cerebral blood flow response to functional activation. J Cereb Blood Flow Metab (2009) 1.60
Gap junctions. Compr Physiol (2012) 1.59
Coordinated release of nucleotides and mucin from human airway epithelial Calu-3 cells. J Physiol (2007) 1.59
ATP and purinergic receptor-dependent membrane traffic in bladder umbrella cells. J Clin Invest (2005) 1.58
Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade. Purinergic Signal (2005) 1.58
Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures. Proc Natl Acad Sci U S A (2003) 1.55
Vesicular and conductive mechanisms of nucleotide release. Purinergic Signal (2012) 1.49
Vesicular ATP is the predominant cause of intercellular calcium waves in astrocytes. J Gen Physiol (2007) 1.43
Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation. Biochem J (2004) 1.42
Circadian regulation of ATP release in astrocytes. J Neurosci (2011) 1.41
Astroglial excitability and gliotransmission: an appraisal of Ca2+ as a signalling route. ASN Neuro (2012) 1.40
Neurone-to-astrocyte signalling in the brain represents a distinct multifunctional unit. J Physiol (2004) 1.40
Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways. Nat Neurosci (2017) 1.38
Tripartite synapses: roles for astrocytic purines in the control of synaptic physiology and behavior. Neuropharmacology (2009) 1.35
Intercellular Ca(2+) waves: mechanisms and function. Physiol Rev (2012) 1.32
Gap junction hemichannels in astrocytes of the CNS. Acta Physiol Scand (2003) 1.31
Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor. Mol Biol Cell (2006) 1.30
Microglial migration mediated by ATP-induced ATP release from lysosomes. Cell Res (2012) 1.25
P2 receptors and neuronal injury. Pflugers Arch (2006) 1.18
PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine. Mol Pain (2011) 1.18
Exocytosis of ATP from astrocyte progenitors modulates spontaneous Ca2+ oscillations and cell migration. Glia (2007) 1.16
Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes. Am J Physiol Cell Physiol (2008) 1.13
Initiation of purinergic signaling by exocytosis of ATP-containing vesicles in liver epithelium. J Biol Chem (2010) 1.13
Astrocytic control of synaptic transmission and plasticity: a target for drugs of abuse? Neuropharmacology (2008) 1.11
Thrombin-promoted release of UDP-glucose from human astrocytoma cells. Br J Pharmacol (2008) 1.08
The purinergic neurotransmitter revisited: a single substance or multiple players? Pharmacol Ther (2014) 1.06
Synaptobrevin2-expressing vesicles in rat astrocytes: insights into molecular characterization, dynamics and exocytosis. J Physiol (2005) 1.06
Regulation of purinergic signaling in biliary epithelial cells by exocytosis of SLC17A9-dependent ATP-enriched vesicles. J Biol Chem (2011) 1.05
Fast subplasma membrane Ca2+ transients control exo-endocytosis of synaptic-like microvesicles in astrocytes. J Neurosci (2008) 1.04
The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects. Curr Top Med Chem (2011) 1.04
K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharmacol (2012) 1.04
Oxygen-glucose deprivation induces ATP release via maxi-anion channels in astrocytes. Purinergic Signal (2007) 1.04
Pathophysiology of astroglial purinergic signalling. Purinergic Signal (2012) 1.03
Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow. Am J Physiol Cell Physiol (2010) 1.02
P2X7 receptors trigger ATP exocytosis and modify secretory vesicle dynamics in neuroblastoma cells. J Biol Chem (2011) 0.98
Diffusion modeling of ATP signaling suggests a partially regenerative mechanism underlies astrocyte intercellular calcium waves. Front Neuroeng (2008) 0.98
Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP. Cell Death Differ (2010) 0.97
Astrocyte calcium signaling and epilepsy. Glia (2012) 0.96
A quantitative model of cortical spreading depression due to purinergic and gap-junction transmission in astrocyte networks. Biophys J (2008) 0.95
Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion. EMBO J (2016) 0.95
Trafficking and fusion of neuropeptide Y-containing dense-core granules in astrocytes. J Neurosci (2008) 0.95
A quantitative model of purinergic junctional transmission of calcium waves in astrocyte networks. Biophys J (2005) 0.95
Amyloid β-peptide directly induces spontaneous calcium transients, delayed intercellular calcium waves and gliosis in rat cortical astrocytes. ASN Neuro (2010) 0.95
Computational quest for understanding the role of astrocyte signaling in synaptic transmission and plasticity. Front Comput Neurosci (2012) 0.94
ATP as a multi-target danger signal in the brain. Front Neurosci (2015) 0.94
Differential sensitivity of brainstem versus cortical astrocytes to changes in pH reveals functional regional specialization of astroglia. J Neurosci (2013) 0.94
Purinergic mechanisms in gliovascular coupling. Semin Cell Dev Biol (2011) 0.94
Roles of P2 receptors in glial cells: focus on astrocytes. Purinergic Signal (2006) 0.92
Coupled ATP and potassium efflux from intercalated cells. Am J Physiol Renal Physiol (2011) 0.92
Detecting fluorescent protein expression and co-localisation on single secretory vesicles with linear spectral unmixing. Eur Biophys J (2006) 0.92
The P2X7 Receptor is an Important Regulator of Extracellular ATP Levels. Front Endocrinol (Lausanne) (2012) 0.92
An essential role for adenosine signaling in alcohol abuse. Curr Drug Abuse Rev (2010) 0.92
Astrocytes shed large membrane vesicles that contain mitochondria, lipid droplets and ATP. Histochem Cell Biol (2012) 0.92
Lrp4 in astrocytes modulates glutamatergic transmission. Nat Neurosci (2016) 0.90
PI3K, Rho, and ROCK play a key role in hypoxia-induced ATP release and ATP-stimulated angiogenic responses in pulmonary artery vasa vasorum endothelial cells. Am J Physiol Lung Cell Mol Physiol (2009) 0.90
ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner. Autophagy (2012) 0.90
Regulation of cell-to-cell communication mediated by astrocytic ATP in the CNS. Purinergic Signal (2005) 0.89
Hemichannels: new roles in astroglial function. Front Physiol (2014) 0.89
ATP synthesis and storage. Purinergic Signal (2012) 0.89
Rod and cone pathway signalling is altered in the P2X7 receptor knock out mouse. PLoS One (2012) 0.88
REST/NRSF governs the expression of dense-core vesicle gliosecretion in astrocytes. J Cell Biol (2011) 0.88
Functional Oxygen Sensitivity of Astrocytes. J Neurosci (2015) 0.88
Purinergic modulation of microglial cell activation. Purinergic Signal (2006) 0.87
Regulated exocytosis in astrocytic signal integration. Neurochem Int (2010) 0.87
5-Nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) stimulates cellular ATP release through exocytosis of ATP-enriched vesicles. J Biol Chem (2009) 0.87
A critical role for purinergic signalling in the mechanisms underlying generation of BOLD fMRI responses. J Neurosci (2015) 0.86
PAR1-activated astrocytes in the nucleus of the solitary tract stimulate adjacent neurons via NMDA receptors. J Neurosci (2015) 0.86
Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy? Front Cell Neurosci (2013) 0.86
ATP hydrolysis pathways and their contributions to pial arteriolar dilation in rats. Am J Physiol Heart Circ Physiol (2011) 0.86
Astrocytic adenosine: from synapses to psychiatric disorders. Philos Trans R Soc Lond B Biol Sci (2014) 0.85
Characterization of AMPA receptors targeted by the climbing fiber transmitter mediating presynaptic inhibition of GABAergic transmission at cerebellar interneuron-Purkinje cell synapses. J Neurosci (2006) 0.85
Neuroprotective roles of the P2Y(2) receptor. Purinergic Signal (2012) 0.84
Loss of calcium/calmodulin-dependent protein kinase II activity in cortical astrocytes decreases glutamate uptake and induces neurotoxic release of ATP. J Biol Chem (2013) 0.84
Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.84
P2 receptor-mediated modulation of neurotransmitter release-an update. Purinergic Signal (2007) 0.84
Peptidomic analyses of mouse astrocytic cell lines and rat primary cultured astrocytes. J Proteome Res (2012) 0.84
Enhanced Na+/H+ exchange activity contributes to the pathogenesis of muscular dystrophy via involvement of P2 receptors. Am J Pathol (2007) 0.84
Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death. Purinergic Signal (2012) 0.83
Different properties of P2X(7) receptor in hippocampal and cortical astrocytes. Purinergic Signal (2009) 0.83
Receptors, ion channels, and signaling mechanisms underlying microglial dynamics. J Biol Chem (2015) 0.82
The role of astroglia in the epileptic brain. Front Pharmacol (2012) 0.81
Micropit: A New Cell Culturing Approach for Characterization of Solitary Astrocytes and Small Networks of these Glial Cells. Front Neuroeng (2008) 0.81
Homeostatic control of brain function - new approaches to understand epileptogenesis. Front Cell Neurosci (2013) 0.81
Astrocytes increase ATP exocytosis mediated calcium signaling in response to microgroove structures. Sci Rep (2015) 0.81
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. Cell Stem Cell (2009) 2.81
Cell cycle control of mammalian neural stem cells: putting a speed limit on G1. Trends Cell Biol (2010) 2.66
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J Neurosci (2011) 2.52
Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels. Sci Signal (2008) 2.27
Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (2007) 2.21
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. EMBO J (2006) 2.17
Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia. J Immunol (2005) 2.09
Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). PLoS Biol (2009) 1.78
Acid sphingomyelinase activity triggers microparticle release from glial cells. EMBO J (2009) 1.78
Neural stem and progenitor cells shorten S-phase on commitment to neuron production. Nat Commun (2011) 1.75
Live imaging at the onset of cortical neurogenesis reveals differential appearance of the neuronal phenotype in apical versus basal progenitor progeny. PLoS One (2008) 1.75
Vesicular transmitter release from astrocytes. Glia (2006) 1.71
SNAP-25 modulation of calcium dynamics underlies differences in GABAergic and glutamatergic responsiveness to depolarization. Neuron (2004) 1.56
Cdks and cyclins link G1 length and differentiation of embryonic, neural and hematopoietic stem cells. Cell Cycle (2010) 1.54
Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors. Glia (2003) 1.54
Myosin II is required for interkinetic nuclear migration of neural progenitors. Proc Natl Acad Sci U S A (2009) 1.53
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One (2008) 1.44
Doxycycline-dependent photoactivated gene expression in eukaryotic systems. Nat Methods (2009) 1.30
Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells. J Biol Chem (2002) 1.28
Block of glutamate-glutamine cycle between astrocytes and neurons inhibits epileptiform activity in hippocampus. J Neurophysiol (2002) 1.28
Role of lipid microdomains in P/Q-type calcium channel (Cav2.1) clustering and function in presynaptic membranes. J Biol Chem (2003) 1.27
Myeloid microvesicles are a marker and therapeutic target for neuroinflammation. Ann Neurol (2012) 1.26
Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes. J Cell Biol (2008) 1.24
Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia. Brain Res Brain Res Rev (2005) 1.24
Regulation of cerebral cortex size and folding by expansion of basal progenitors. EMBO J (2013) 1.24
SYN1 loss-of-function mutations in autism and partial epilepsy cause impaired synaptic function. Hum Mol Genet (2011) 1.23
Single-cell detection of microRNAs in developing vertebrate embryos after acute administration of a dual-fluorescence reporter/sensor plasmid. Biotechniques (2006) 1.23
Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance. EMBO J (2006) 1.22
Transcriptome sequencing during mouse brain development identifies long non-coding RNAs functionally involved in neurogenic commitment. EMBO J (2013) 1.19
Cholesterol reduction impairs exocytosis of synaptic vesicles. J Cell Sci (2010) 1.18
Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels. Proc Natl Acad Sci U S A (2007) 1.17
Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism. EMBO J (2012) 1.16
Unique luminal localization of VGAT-C terminus allows for selective labeling of active cortical GABAergic synapses. J Neurosci (2008) 1.14
Microglial microvesicle secretion and intercellular signaling. Front Physiol (2012) 1.12
A role for P2X7 in microglial proliferation. J Neurochem (2006) 1.10
Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain. J Exp Med (2011) 1.09
Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein. Proc Natl Acad Sci U S A (2011) 1.07
The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury. Brain (2009) 1.07
Synaptobrevin2-expressing vesicles in rat astrocytes: insights into molecular characterization, dynamics and exocytosis. J Physiol (2005) 1.06
Purinoceptor-mediated calcium signaling in primary neuron-glia trigeminal cultures. Cell Calcium (2007) 1.05
Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation. J Biol Chem (2011) 1.05
Entering neurons: botulinum toxins and synaptic vesicle recycling. EMBO Rep (2006) 1.05
SNAP-25 in neuropsychiatric disorders. Ann N Y Acad Sci (2009) 1.05
Microvesicles: novel biomarkers for neurological disorders. Front Physiol (2012) 1.04
Mechanisms of transport and exocytosis of dense-core granules containing tissue plasminogen activator in developing hippocampal neurons. J Neurosci (2005) 1.04
Internalization and mechanism of action of clostridial toxins in neurons. Neurotoxicology (2005) 1.01
Endogenous SNAP-25 regulates native voltage-gated calcium channels in glutamatergic neurons. J Biol Chem (2010) 1.01
Oxytocin receptor elicits different EGFR/MAPK activation patterns depending on its localization in caveolin-1 enriched domains. Oncogene (2003) 1.00
Cracking down on inhibition: selective removal of GABAergic interneurons from hippocampal networks. J Neurosci (2012) 1.00
Defective secretion of islet hormones in chromogranin-B deficient mice. PLoS One (2010) 0.99
Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons. J Biol Chem (2002) 0.99
Regulated delivery of AMPA receptor subunits to the presynaptic membrane. EMBO J (2003) 0.98
Traffic of botulinum toxins A and E in excitatory and inhibitory neurons. Traffic (2007) 0.97
The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells. J Biol Chem (2013) 0.97
Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function. J Biol Chem (2010) 0.97
Heterogeneous expression of SNAP-25 in rat and human brain. J Comp Neurol (2008) 0.97
Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase beta interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis. J Cell Sci (2002) 0.97
The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage. Glia (2011) 0.96
Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 Subunit. Neuron (2012) 0.96
The H(+) vacuolar ATPase maintains neural stem cells in the developing mouse cortex. Stem Cells Dev (2011) 0.95
Age-related cognitive decline: can neural stem cells help us? Aging (Albany NY) (2012) 0.93
Cross talk between vestibular neurons and Schwann cells mediates BDNF release and neuronal regeneration. Brain Cell Biol (2007) 0.93
Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update. Neuron Glia Biol (2010) 0.93