Deborah K Morrison

Author PubWeight™ 47.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Regulation of Raf-1 by direct feedback phosphorylation. Mol Cell 2005 5.88
2 Unlocking the code of 14-3-3. J Cell Sci 2004 2.58
3 Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol 2002 2.54
4 Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites. Curr Biol 2003 1.98
5 Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling. Mol Cell Biol 2009 1.81
6 Signaling dynamics of the KSR1 scaffold complex. Proc Natl Acad Sci U S A 2009 1.76
7 CK2 Is a component of the KSR1 scaffold complex that contributes to Raf kinase activation. Curr Biol 2006 1.69
8 AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat Cell Biol 2010 1.64
9 Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy. Genes Dev 2012 1.60
10 KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity. Cell Metab 2009 1.53
11 KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals. Mol Cell 2009 1.39
12 Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling. Mol Cell 2013 1.37
13 14-3-3 Proteins: diverse functions in cell proliferation and cancer progression. Semin Cell Dev Biol 2011 1.31
14 Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway. J Biol Chem 2002 1.30
15 Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation. Neuron 2006 1.26
16 RAF inhibitor-induced KSR1/B-RAF binding and its effects on ERK cascade signaling. Curr Biol 2011 1.22
17 Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR). J Mol Biol 2002 1.14
18 Morphogenesis during Xenopus gastrulation requires Wee1-mediated inhibition of cell proliferation. Development 2004 1.09
19 The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling. Genes Dev 2010 1.05
20 Signal transduction: implications for Ras-dependent ERK signaling. Curr Biol 2004 1.04
21 Functional analysis of C-TAK1 substrate binding and identification of PKP2 as a new C-TAK1 substrate. EMBO J 2003 1.01
22 Inhibition of lysophosphatidic acid acyltransferase beta disrupts proliferative and survival signals in normal cells and induces apoptosis of tumor cells. Mol Cancer Ther 2003 1.00
23 FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4. Nat Commun 2013 0.99
24 Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells. Mol Cell Biol 2011 0.97
25 BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation. J Biol Chem 2003 0.96
26 CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage. Proc Natl Acad Sci U S A 2010 0.94
27 Caspase-dependent cleavage disrupts the ERK cascade scaffolding function of KSR1. J Biol Chem 2007 0.93
28 dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila. Biochem J 2003 0.92
29 LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation. Mol Cell 2012 0.91
30 Overexpression of kinase suppressor of Ras upregulates the high-molecular-weight tropomyosin isoforms in ras-transformed NIH 3T3 fibroblasts. Mol Cell Biol 2003 0.90
31 KSR regulation of the Raf-MEK-ERK cascade. Methods Enzymol 2006 0.80
32 Complexity in KSR function revealed by Raf inhibitor and KSR structure studies. Small GTPases 2011 0.79
33 A CC-SAM, for coiled coil-sterile α motif, domain targets the scaffold KSR-1 to specific sites in the plasma membrane. Sci Signal 2012 0.79
34 Proteomic analysis of scaffold proteins in the ERK cascade. Methods Mol Biol 2010 0.79
35 Assay of Raf-1 activity. Methods Enzymol 2002 0.75
36 Cancer: enzymes play molecular tag. Nature 2004 0.75