Published in Proc Natl Acad Sci U S A on August 30, 2010
The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis. EMBO J (2010) 1.41
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting. Proc Natl Acad Sci U S A (2012) 1.34
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1. Cell Death Differ (2011) 1.07
The many faces of C/EBPδ and their relevance for inflammation and cancer. Int J Biol Sci (2013) 1.06
Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells. Mol Cell Biol (2011) 0.97
Towards a molecular understanding of the fanconi anemia core complex. Anemia (2012) 0.84
Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal. PLoS One (2013) 0.78
Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma. Oncotarget (2015) 0.78
C/EBPδ deficiency sensitizes mice to ionizing radiation-induced hematopoietic and intestinal injury. PLoS One (2014) 0.78
C/EBPδ: friend or foe? a novel role for C/EBPδ in metastasis. EMBO J (2010) 0.76
Identification of novel exonic mobile element insertions in epithelial ovarian cancers. Hum Genome Var (2015) 0.75
GammaH2AX and cancer. Nat Rev Cancer (2008) 9.77
CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J (2002) 6.83
The Fanconi anaemia/BRCA pathway. Nat Rev Cancer (2003) 5.89
How the fanconi anemia pathway guards the genome. Annu Rev Genet (2009) 4.94
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science (2009) 4.85
gammaH2AX: a sensitive molecular marker of DNA damage and repair. Leukemia (2010) 3.46
A gene-expression signature to predict survival in breast cancer across independent data sets. Oncogene (2006) 3.21
Fanconi anemia (cross)linked to DNA repair. Cell (2005) 2.78
Molecular markers in ductal carcinoma in situ of the breast. Mol Cancer Res (2003) 2.55
DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem (1996) 2.38
A SAGE (serial analysis of gene expression) view of breast tumor progression. Cancer Res (2001) 2.22
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. EMBO J (2002) 2.17
Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processing. Mol Cell Biol (1999) 2.06
The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. Blood (2007) 1.84
Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights. Mutat Res (2009) 1.80
Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein alpha. J Biol Chem (2003) 1.79
Genetic basis of Fanconi anemia. Curr Opin Hematol (2003) 1.76
Selectively enhanced contextual fear conditioning in mice lacking the transcriptional regulator CCAAT/enhancer binding protein delta. Proc Natl Acad Sci U S A (1998) 1.59
The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase. Mol Genet Metab (2001) 1.46
Importins and beyond: non-conventional nuclear transport mechanisms. Traffic (2009) 1.41
BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines. Cancer Res (2007) 1.33
Generation of truncated C/EBPbeta isoforms by in vitro proteolysis. J Biol Chem (2000) 1.21
Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex. J Biol Chem (2008) 1.21
Checkpoint mechanisms at the intersection between DNA damage and repair. DNA Repair (Amst) (2009) 1.18
Loss of CCAAT/enhancer binding protein delta promotes chromosomal instability. Oncogene (2004) 1.16
Flow cytometric characterization of the response of Fanconi's anemia cells to mitomycin C treatment. Cytometry (1982) 1.15
Fanconi anemia. Hematol Oncol Clin North Am (2009) 1.11
C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression. Proc Natl Acad Sci U S A (2010) 1.09
Promoter methylation reduces C/EBPdelta (CEBPD) gene expression in the SUM-52PE human breast cancer cell line and in primary breast tumors. Breast Cancer Res Treat (2005) 1.08
Regulation of the Fanconi anemia pathway by monoubiquitination. Semin Cancer Biol (2003) 1.08
C/EBP proteins contain nuclear localization signals imbedded in their basic regions. Gene Expr (1997) 1.02
Significance of the Fanconi anemia FANCD2 protein in sporadic and metastatic human breast cancer. Am J Pathol (2010) 0.94
FANCD2 associated with sporadic breast cancer risk. Carcinogenesis (2006) 0.93
Transcriptional up-regulation of SOD1 by CEBPD: a potential target for cisplatin resistant human urothelial carcinoma cells. Biochem Pharmacol (2010) 0.92
The Fanconi anaemia genome stability and tumour suppressor network. Mutagenesis (2002) 0.92
Importin 4 is responsible for ligand-independent nuclear translocation of vitamin D receptor. J Biol Chem (2005) 0.91
Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7. Biochem Biophys Res Commun (2009) 0.90
Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus. Mol Cell Biol (2007) 0.88
The cell growth inhibitory transcription factor C/EBPdelta is expressed in human meningiomas in association with low histological grade and proliferation index. J Neurooncol (2009) 0.86
Temporal and spatial profiling of nuclei-associated proteins upon TNF-alpha/NF-kappaB signaling. Cell Res (2009) 0.85
Schistosoma mansoni: the IMP4 gene is involved in DNA repair/tolerance after treatment with alkylating agent methyl methane sulfonate. Exp Parasitol (2006) 0.80
The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature (2002) 18.30
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell (2003) 15.43
Regulation of Raf-1 by direct feedback phosphorylation. Mol Cell (2005) 5.88
Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program. Cancer Res (2004) 5.88
Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. J Clin Oncol (2008) 5.27
alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer. JAMA (2002) 5.07
HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. Nat Immunol (2008) 5.01
The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol Cell Proteomics (2004) 4.48
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc Natl Acad Sci U S A (2007) 4.20
An accurate mass tag strategy for quantitative and high-throughput proteome measurements. Proteomics (2002) 4.10
Telomerase modulates Wnt signalling by association with target gene chromatin. Nature (2009) 3.96
The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. Am J Surg Pathol (2013) 3.68
Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages. J Virol (2006) 3.59
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Mol Cell (2006) 3.38
Characterization of the low molecular weight human serum proteome. Mol Cell Proteomics (2003) 3.34
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Science (2009) 3.34
Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell (2006) 3.16
Renal mass biopsy--a renaissance? J Urol (2007) 3.12
MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility. Science (2009) 2.86
An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma. Cancer Cell (2011) 2.78
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell (2011) 2.73
Importance of communication between producers and consumers of publicly available experimental data. J Natl Cancer Inst (2005) 2.63
Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Res (2010) 2.61
Unlocking the code of 14-3-3. J Cell Sci (2004) 2.58
Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol (2002) 2.54
The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification. Biochem Biophys Res Commun (2002) 2.51
Surgical resection of renal cell carcinoma after targeted therapy. J Urol (2009) 2.29
An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide. Proc Natl Acad Sci U S A (2004) 2.28
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metab (2009) 2.27
Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly. Cell (2008) 2.20
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism. J Biol Chem (2010) 2.20
Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs. Nature (2009) 2.19
CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling. Proc Natl Acad Sci U S A (2001) 2.15
Structural and thermodynamic properties of selective ion binding in a K+ channel. PLoS Biol (2007) 2.10
Circulating estrogens and estrogens within the breast among postmenopausal BRCA1/2 mutation carriers. Breast Cancer Res Treat (2014) 2.10
Renal angiomyolipoma: clinicopathologic study of 194 cases with emphasis on the epithelioid histology and tuberous sclerosis association. Am J Surg Pathol (2009) 2.10
TMPRSS2-ERG gene fusion prevalence and class are significantly different in prostate cancer of Caucasian, African-American and Japanese patients. Prostate (2010) 2.05
Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. J Clin Oncol (2008) 2.00
Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites. Curr Biol (2003) 1.98
NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J Neurosci (2007) 1.95
An investigation into the human serum "interactome". Electrophoresis (2004) 1.93
Proteomic analysis of formalin-fixed prostate cancer tissue. Mol Cell Proteomics (2005) 1.91
Quantitative measurement of endogenous estrogens and estrogen metabolites in human serum by liquid chromatography-tandem mass spectrometry. Anal Chem (2007) 1.91
Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival. Nature (2008) 1.91
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. J Clin Invest (2013) 1.89
Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling. PLoS Negl Trop Dis (2009) 1.88
von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma. J Urol (2008) 1.87
Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy. Am J Surg Pathol (2010) 1.87
Fusion of ALK to the Ran-binding protein 2 (RANBP2) gene in inflammatory myofibroblastic tumor. Genes Chromosomes Cancer (2003) 1.86
Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry. Anal Chem (2005) 1.85
Proteomic analysis of laser-captured paraffin-embedded tissues: a molecular portrait of head and neck cancer progression. Clin Cancer Res (2008) 1.83
The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation. Nat Med (2007) 1.81
Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling. Mol Cell Biol (2009) 1.81
An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis. Neuron (2002) 1.79
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination. Cancer Cell (2009) 1.77
Signaling dynamics of the KSR1 scaffold complex. Proc Natl Acad Sci U S A (2009) 1.76
FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res (2013) 1.76
Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis. J Biol Chem (2008) 1.73
Detection of bladder cancer in human urine by metabolomic profiling using high performance liquid chromatography/mass spectrometry. J Urol (2008) 1.72
Increased serum levels of complement C3a anaphylatoxin indicate the presence of colorectal tumors. Gastroenterology (2006) 1.72
CK2 Is a component of the KSR1 scaffold complex that contributes to Raf kinase activation. Curr Biol (2006) 1.69
A sulfilimine bond identified in collagen IV. Science (2009) 1.69
Coupling morphogenesis to mitotic entry. Proc Natl Acad Sci U S A (2004) 1.68
Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin. Nat Cell Biol (2009) 1.68
Concerted mechanism of Swe1/Wee1 regulation by multiple kinases in budding yeast. EMBO J (2005) 1.67
A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma. Cancer Res (2004) 1.65
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat Cell Biol (2010) 1.64
Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation. Genes Dev (2009) 1.62
Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin. J Cell Biol (2007) 1.61
Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast. Proc Natl Acad Sci U S A (2009) 1.60
Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy. Genes Dev (2012) 1.60
microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network. Carcinogenesis (2010) 1.59
Recommendations for biomarker identification and qualification in clinical proteomics. Sci Transl Med (2010) 1.59
Can saturation biopsy predict prostate cancer localization in radical prostatectomy specimens: a correlative study and implications for focal therapy. Urology (2010) 1.58
A preoperative prognostic nomogram for solid enhancing renal tumors 7 cm or less amenable to partial nephrectomy. J Urol (2007) 1.57
Characterization and quantitation of membrane proteomes using multidimensional MS-based proteomic technologies. Expert Rev Proteomics (2004) 1.56
Serum and plasma proteomics. Chem Rev (2007) 1.56
Gleason 6 prostate tumors diagnosed in the PSA era do not demonstrate the capacity for metastatic spread at the time of radical prostatectomy. Urology (2013) 1.56
Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells. Dev Cell (2009) 1.55
Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid. J Urol (2008) 1.55
The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells. Cancer Res (2007) 1.55
Proteomic profiling of differentiating osteoblasts. Expert Rev Proteomics (2006) 1.54
KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity. Cell Metab (2009) 1.53
Estrogen metabolism and risk of breast cancer in postmenopausal women. J Natl Cancer Inst (2012) 1.53
Analytical and statistical approaches to metabolomics research. J Sep Sci (2009) 1.52
Expression of PTEN and mTOR in sacral chordoma and association with poor prognosis. Med Oncol (2014) 1.50