Published in Eur J Immunol on July 01, 2009
A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma. Blood (2010) 1.89
Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection. Mucosal Immunol (2010) 1.78
IL-17 family member cytokines: regulation and function in innate immunity. Cytokine Growth Factor Rev (2010) 1.76
Tc17 CD8 T cells: functional plasticity and subset diversity. J Immunol (2009) 1.54
CD8(+) T cells mediate RAS-induced psoriasis-like skin inflammation through IFN-γ. J Invest Dermatol (2012) 1.49
IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections. J Immunol (2010) 1.43
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest (2012) 1.40
Mechanisms controlling Th17 cytokine expression and host defense. J Leukoc Biol (2011) 1.33
Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses. Proc Natl Acad Sci U S A (2011) 1.31
Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers. J Virol (2010) 1.15
Cytokines and the inception of CD8 T cell responses. Trends Immunol (2011) 1.07
The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells. Proc Natl Acad Sci U S A (2013) 1.07
CD8 positive T cells express IL-17 in patients with chronic obstructive pulmonary disease. Respir Res (2011) 1.07
Intestinal T-cell responses in celiac disease - impact of celiac disease associated bacteria. PLoS One (2013) 1.07
Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype. J Immunol (2010) 1.06
CD161-expressing human T cells. Front Immunol (2011) 1.05
Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms. J Immunol (2013) 0.96
IL-17 in the rheumatologist's line of sight. Biomed Res Int (2013) 0.95
Increased number of Tc17 and correlation with Th17 cells in patients with immune thrombocytopenia. PLoS One (2011) 0.94
Characteristics of IL-17 induction by Schistosoma japonicum infection in C57BL/6 mouse liver. Immunology (2013) 0.92
Diversity of IL-17-producing T lymphocytes. Cell Mol Life Sci (2012) 0.91
Inflammatory cytokines determine the susceptibility of human CD8 T cells to Fas-mediated activation-induced cell death through modulation of FasL and c-FLIP(S) expression. J Biol Chem (2011) 0.90
T cell responses: naive to memory and everything in between. Adv Physiol Educ (2013) 0.89
Interleukin-1 receptor and caspase-1 are required for the Th17 response in nitrogen dioxide-promoted allergic airway disease. Am J Respir Cell Mol Biol (2013) 0.88
CD8(+) T-Cells as Immune Regulators of Multiple Sclerosis. Front Immunol (2015) 0.86
Persistence of Th17/Tc17 cell expression upon smoking cessation in mice with cigarette smoke-induced emphysema. Clin Dev Immunol (2013) 0.86
CD8(+) T cells in multiple sclerosis. Expert Opin Ther Targets (2013) 0.86
CD8+ T cells induce thyroid epithelial cell hyperplasia and fibrosis. J Immunol (2011) 0.85
Secretion of interleukin-17 by CD8+ T cells expressing CD146 (MCAM). Clin Immunol (2014) 0.83
Distribution and functional plasticity of peripheral blood Th(c)17 and Th(c)1 in rheumatoid arthritis. Rheumatol Int (2013) 0.83
Antigen-specific CD8(+) T cells fail to respond to Shigella flexneri. Infect Immun (2011) 0.82
The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development. PLoS One (2014) 0.82
Praziquantel facilitates IFN-γ-producing CD8+ T cells (Tc1) and IL-17-producing CD8+ T cells (Tc17) responses to DNA vaccination in mice. PLoS One (2011) 0.82
Effect of chronic morphine administration on circulating T cell population dynamics in rhesus macaques. J Neuroimmunol (2013) 0.80
Development of autoimmune diabetes in the absence of detectable IL-17A in a CD8-driven virally induced model. J Immunol (2011) 0.80
The inducible costimulator augments Tc17 cell responses to self and tumor tissue. J Immunol (2015) 0.80
Tc17 cells in patients with uterine cervical cancer. PLoS One (2014) 0.79
Epitope-specific CD8+ T cells play a differential pathogenic role in the development of a viral disease model for multiple sclerosis. J Virol (2012) 0.79
Exploring the roles of CD8(+) T lymphocytes in the pathogenesis of autoimmune demyelination. Semin Immunopathol (2010) 0.79
Role of interleukin-22 in inflammatory bowel disease. World J Gastroenterol (2014) 0.78
Use of praziquantel as an adjuvant enhances protection and Tc-17 responses to killed H5N1 virus vaccine in mice. PLoS One (2012) 0.78
Dendritic Cell-Induced Th1 and Th17 Cell Differentiation for Cancer Therapy. Vaccines (Basel) (2013) 0.78
CXCR4 inhibitor attenuates ovalbumin-induced airway inflammation and hyperresponsiveness by inhibiting Th17 and Tc17 cell immune response. Exp Ther Med (2016) 0.78
IL-17+ CD8+ T cells: Differentiation, phenotype and role in inflammatory disease. Immunol Lett (2016) 0.78
Anti-inflammatory effect of qingpeng ointment in atopic dermatitis-like murine model. Evid Based Complement Alternat Med (2013) 0.78
Change of paradigm: CD8+ T cells as important helper for CD4+ T cells during asthma and autoimmune encephalomyelitis. Allergo J Int (2015) 0.77
IL-17A expression in HIV-specific CD8 T cells is regulated by IL-4/IL-13 following HIV-1 prime-boost immunization. J Interferon Cytokine Res (2014) 0.77
Nocardia brasiliensis induces an immunosuppressive microenvironment that favors chronic infection in BALB/c mice. Infect Immun (2012) 0.77
Distinctive expression of interleukin-23 receptor subunits on human Th17 and γδ T cells. Immunol Cell Biol (2016) 0.76
Infiltration of IL-17-Producing T Cells and Treg Cells in a Mouse Model of Smoke-Induced Emphysema. Inflammation (2016) 0.76
IL-17-expressing CD4⁺ and CD8⁺ T lymphocytes in human toxoplasmosis. Mediators Inflamm (2014) 0.76
Role of interferon-γ and cytotoxic T lymphocytes in intraocular tumor rejection. J Leukoc Biol (2015) 0.76
Translational utility of experimental autoimmune encephalomyelitis: recent developments. J Inflamm Res (2015) 0.76
IL-21R signaling suppresses IL-17+ gamma delta T cell responses and production of IL-17 related cytokines in the lung at steady state and after Influenza A virus infection. PLoS One (2015) 0.75
Interleukin-17A and Neutrophils in a Murine Model of Bird-Related Hypersensitivity Pneumonitis. PLoS One (2015) 0.75
Blockade of IL-23 ameliorates allergic lung inflammation via decreasing the infiltration of Tc17 cells. Arch Med Sci (2016) 0.75
Effects of Low-Dose and Long-Term Treatment with Erythromycin on Interleukin-17 and Interleukin-23 in Peripheral Blood and Induced Sputum in Patients with Stable Chronic Obstructive Pulmonary Disease. Mediators Inflamm (2016) 0.75
The role of IL-23/Th17 pathway in patients with primary immune thrombocytopenia. PLoS One (2015) 0.75
The differentiation and plasticity of Tc17 cells are regulated by CTLA-4-mediated effects on STATs. Oncoimmunology (2017) 0.75
CD73-mediated adenosine production promotes stem cell-like properties in mouse Tc17 cells. Immunology (2015) 0.75
Differential Frequency of CD8+ T Cell Subsets in Multiple Sclerosis Patients with Various Clinical Patterns. PLoS One (2016) 0.75
Human lymph-node CD8(+) T cells display an altered phenotype during systemic autoimmunity. Clin Transl Immunology (2016) 0.75
Peripheral Tc17 and Tc17/Interferon-γ Cells are Increased and Associated with Lung Function in Patients with Chronic Obstructive Pulmonary Disease. Chin Med J (Engl) (2016) 0.75
Single-cell analysis reveals sexually dimorphic repertoires of Interferon-γ and IL-17A producing T cells in salivary glands of Sjögren's syndrome mice. Sci Rep (2017) 0.75
Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy. Cell Metab (2017) 0.75
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol (2007) 5.83
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol (2003) 5.07
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature (2012) 4.04
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity (2010) 3.64
Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol (2010) 2.70
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4. Proc Natl Acad Sci U S A (2002) 2.61
γδ T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism. Immunity (2010) 2.54
Crystal structure of a soluble CD28-Fab complex. Nat Immunol (2005) 2.46
Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis. J Immunol (2007) 2.43
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17. J Exp Med (2009) 2.28
Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses. J Exp Med (2002) 2.20
IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype. Proc Natl Acad Sci U S A (2008) 2.13
Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412. Blood (2011) 2.12
The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis. J Am Soc Nephrol (2009) 2.06
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity. Proc Natl Acad Sci U S A (2011) 1.98
Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation. Immunity (2011) 1.96
Th memory for interleukin-17 expression is stable in vivo. Eur J Immunol (2008) 1.94
Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo. J Immunol (2005) 1.85
IL-27 inhibits the development of regulatory T cells via STAT3. Int Immunol (2007) 1.84
Assessment of unspecific near-infrared dyes in laser-induced fluorescence imaging of experimental arthritis. Acad Radiol (2006) 1.80
Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. J Exp Med (2005) 1.79
Lymphocyte-derived ACh regulates local innate but not adaptive immunity. Proc Natl Acad Sci U S A (2013) 1.78
Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice. J Immunol (2004) 1.77
Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE. J Exp Med (2011) 1.72
Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing. Immunol Rev (2005) 1.71
Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists. J Exp Med (2003) 1.70
Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist. Eur J Immunol (2003) 1.70
Cell-intrinsic and -extrinsic control of Treg-cell homeostasis and function revealed by induced CD28 deletion. Eur J Immunol (2012) 1.66
Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08. Eur J Immunol (2014) 1.61
In vivo molecular imaging of experimental joint inflammation by combined (18)F-FDG positron emission tomography and computed tomography. Arthritis Res Ther (2010) 1.60
Type 1 diabetes in BioBreeding rats is critically linked to an imbalance between Th17 and regulatory T cells and an altered TCR repertoire. J Immunol (2010) 1.59
Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes. J Immunol (2003) 1.54
Oligodendrocytes enforce immune tolerance of the uninfected brain by purging the peripheral repertoire of autoreactive CD8+ T cells. Immunity (2012) 1.50
Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice. PLoS One (2009) 1.44
Autoregulation of Th1-mediated inflammation by twist1. J Exp Med (2008) 1.43
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest (2012) 1.40
Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences. Proc Natl Acad Sci U S A (2005) 1.38
CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis. J Am Soc Nephrol (2010) 1.34
CD28 superagonists put a break on autoimmunity by preferentially activating CD4+CD25+ regulatory T cells. Autoimmun Rev (2005) 1.32
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation. Proc Natl Acad Sci U S A (2012) 1.32
IFN-gamma represses IL-4 expression via IRF-1 and IRF-2. Immunity (2002) 1.32
IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells. Eur J Immunol (2010) 1.31
CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis. J Immunol (2009) 1.29
IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease. J Immunol (2012) 1.26
CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis. J Immunol (2011) 1.25
CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis. J Clin Invest (2014) 1.24
The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6. J Clin Invest (2008) 1.24
CC chemokine receptor 7 expression by effector/memory CD4+ T cells depends on antigen specificity and tissue localization during influenza A virus infection. J Virol (2004) 1.23
Organ-specific CD4+ T cell response during Listeria monocytogenes infection. J Immunol (2002) 1.22
A role for IL-18 in protective immunity against Mycobacterium tuberculosis. Eur J Immunol (2010) 1.22
Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection. Eur J Immunol (2004) 1.20
Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium. Proc Natl Acad Sci U S A (2002) 1.18
The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum. EMBO Rep (2007) 1.18
Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection. J Exp Med (2005) 1.15
c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells. Eur J Immunol (2010) 1.14
DNA methylation of TH1/TH2 cytokine genes affects sensitization and progress of experimental asthma. J Allergy Clin Immunol (2012) 1.14
Characterization of the renal CD4+ T-cell response in experimental autoimmune glomerulonephritis. Kidney Int (2012) 1.13
The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands. Int Immunol (2006) 1.13
Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits. FEBS Lett (2003) 1.12
IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss. J Immunol (2011) 1.12
Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis. Ann Rheum Dis (2010) 1.12
Epstein-barr virus: environmental trigger of multiple sclerosis? J Virol (2007) 1.11
Mast cell-mediated antigen presentation regulates CD8+ T cell effector functions. Immunity (2009) 1.10
Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells. J Immunol (2002) 1.09
Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system. Brain (2008) 1.08
Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritis. Kidney Int (2012) 1.08
Mitogenic CD28 signals require the exchange factor Vav1 to enhance TCR signaling at the SLP-76-Vav-Itk signalosome. J Immunol (2007) 1.08
IL-2 and autoimmune disease. Cytokine Growth Factor Rev (2002) 1.07
Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss. Am J Pathol (2009) 1.07
Antigen targeting to plasmacytoid dendritic cells via Siglec-H inhibits Th cell-dependent autoimmunity. J Immunol (2011) 1.07
IRF4 regulates IL-17A promoter activity and controls RORγt-dependent Th17 colitis in vivo. Inflamm Bowel Dis (2011) 1.07
The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells. Proc Natl Acad Sci U S A (2013) 1.07
Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis. Ann Rheum Dis (2010) 1.06
Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells. J Immunol (2005) 1.06
IRF4 at the crossroads of effector T-cell fate decision. Eur J Immunol (2014) 1.04
The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast cells. Blood (2010) 1.04
Enhanced TCR-induced apoptosis in interferon regulatory factor 4-deficient CD4(+) Th cells. J Exp Med (2004) 1.04