Published in Mol Immunol on June 26, 2009
Evolution of the porcine (Sus scrofa domestica) immunoglobulin kappa locus through germline gene conversion. Immunogenetics (2011) 0.97
Evolutionary genomics of immunoglobulin-encoding Loci in vertebrates. Curr Genomics (2012) 0.82
Delineating Rearrangements in Single Yeast Artificial Chromosomes by Quantitative DNA Fiber Mapping. Open Genomics J (2009) 0.75
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell (1986) 20.08
MEME: discovering and analyzing DNA and protein sequence motifs. Nucleic Acids Res (2006) 15.32
TRANSFAC: a database on transcription factors and their DNA binding sites. Nucleic Acids Res (1996) 13.50
Correct transcription of an immunoglobulin kappa gene requires an upstream fragment containing conserved sequence elements. Nature (1984) 7.66
Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science (1987) 7.63
Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells. Nature (1981) 3.64
PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity. Mol Cell Biol (1992) 3.32
Two pairs of recombination signals are sufficient to cause immunoglobulin V-(D)-J joining. Science (1987) 2.74
Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain. Cell (1980) 2.68
A uniform deleting element mediates the loss of kappa genes in human B cells. Nature (1985) 2.65
B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits. Mol Cell Biol (1991) 2.28
A conserved sequence in the immunoglobulin J kappa-C kappa intron: possible enhancer element. Nature (1983) 2.24
Long-range interactions between three transcriptional enhancers, active Vkappa gene promoters, and a 3' boundary sequence spanning 46 kilobases. Mol Cell Biol (2005) 2.06
The new mutation theory of phenotypic evolution. Proc Natl Acad Sci U S A (2007) 1.97
Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement. Immunity (1996) 1.96
The human CK gene segment and the kappa deleting element are closely linked. Nucleic Acids Res (1986) 1.69
Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation. Nat Immunol (2002) 1.63
Deletions of kappa chain constant region genes in mouse lambda chain-producing B cells involve intrachromosomal DNA recombinations similar to V-J joining. Proc Natl Acad Sci U S A (1985) 1.61
Normal human B cells display ordered light chain gene rearrangements and deletions. J Exp Med (1982) 1.58
The importance of the 3'-enhancer region in immunoglobulin kappa gene expression. Nucleic Acids Res (1990) 1.56
Human immunoglobulin kappa gene enhancer: chromatin structure analysis at high resolution. Mol Cell Biol (1987) 1.29
The kappa-deleting element. Germline and rearranged, duplicated and dispersed forms. J Exp Med (1988) 1.23
Evolutionary dynamics of the immunoglobulin heavy chain variable region genes in vertebrates. Immunogenetics (2008) 1.09
Chromatin structural analyses of the mouse Igkappa gene locus reveal new hypersensitive sites specifying a transcriptional silencer and enhancer. J Biol Chem (2002) 1.08
Evolutionary redefinition of immunoglobulin light chain isotypes in tetrapods using molecular markers. Proc Natl Acad Sci U S A (2008) 1.05
Unraveling the consecutive recombination events in the human IGK locus. J Immunol (2004) 1.04
The human kappa deleting element and the mouse recombining segment share DNA sequence homology. Nucleic Acids Res (1987) 1.01
Different E-box regulatory sequences are functionally distinct when placed within the context of the troponin I enhancer. Nucleic Acids Res (1992) 1.01
Evolutionary origin and genomic organization of micro-RNA genes in immunoglobulin lambda variable region gene family. Mol Biol Evol (2009) 0.99
Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus. Blood (2001) 0.98
The Downstream Transcriptional Enhancer, Ed, positively regulates mouse Ig kappa gene expression and somatic hypermutation. J Immunol (2008) 0.98
Characterization of the human immunoglobulin kappa gene 3' enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints. Mol Cell Biol (1992) 0.96
Heterogeneity in junctional regions of immunoglobulin kappa deleting element rearrangements in B cell leukemias: a new molecular target for detection of minimal residual disease. Leukemia (1997) 0.92
Binding of USF to a non-canonical E-box following stress results in a cell-specific derepression of the lama3 gene. Nucleic Acids Res (2002) 0.91
Novel recombinations of the IG kappa-locus that result in allelic exclusion. J Immunol (1990) 0.89
Detection of immunoglobulin kappa light-chain gene rearrangement patterns by Southern blot analysis. Leukemia (1994) 0.88
Light chain isotype regulation in the horse. Characterization of Ig kappa genes. J Immunol (1994) 0.84
Organization of the transcription factor binding sites in the kappa Ig intron enhancer. Effects of position, orientation, and spacing. J Immunol (1994) 0.83
Immunoglobulin kappa gene rearrangements between the kappa deleting element and Jkappa recombination signal sequences in acute lymphoblastic leukemia and normal hematopoiesis. Leukemia (2000) 0.77
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol (2011) 220.97
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol (2007) 168.76
MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform (2004) 72.40
MEGA: a biologist-centric software for evolutionary analysis of DNA and protein sequences. Brief Bioinform (2008) 24.69
Prospects for inferring very large phylogenies by using the neighbor-joining method. Proc Natl Acad Sci U S A (2004) 20.53
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell (2005) 5.10
Estimation of divergence times for major lineages of primate species. Mol Biol Evol (2003) 3.52
POPTREE2: Software for constructing population trees from allele frequency data and computing other population statistics with Windows interface. Mol Biol Evol (2009) 2.68
Overcredibility of molecular phylogenies obtained by Bayesian phylogenetics. Proc Natl Acad Sci U S A (2002) 2.63
Extensive gains and losses of olfactory receptor genes in mammalian evolution. PLoS One (2007) 2.35
Evolutionary dynamics of olfactory receptor genes in fishes and tetrapods. Proc Natl Acad Sci U S A (2005) 2.32
Evolution of olfactory receptor genes in the human genome. Proc Natl Acad Sci U S A (2003) 1.97
Evolutionary dynamics of olfactory and other chemosensory receptor genes in vertebrates. J Hum Genet (2006) 1.94
Reliabilities of identifying positive selection by the branch-site and the site-prediction methods. Proc Natl Acad Sci U S A (2009) 1.94
Genomic drift and copy number variation of sensory receptor genes in humans. Proc Natl Acad Sci U S A (2007) 1.80
Acceleration of genomic evolution caused by enhanced mutation rate in endocellular symbionts. Proc Natl Acad Sci U S A (2002) 1.79
Origins and evolution of the recA/RAD51 gene family: evidence for ancient gene duplication and endosymbiotic gene transfer. Proc Natl Acad Sci U S A (2006) 1.72
Evolution of F-box genes in plants: different modes of sequence divergence and their relationships with functional diversification. Proc Natl Acad Sci U S A (2009) 1.70
False-positive selection identified by ML-based methods: examples from the Sig1 gene of the diatom Thalassiosira weissflogii and the tax gene of a human T-cell lymphotropic virus. Mol Biol Evol (2004) 1.64
Type I MADS-box genes have experienced faster birth-and-death evolution than type II MADS-box genes in angiosperms. Proc Natl Acad Sci U S A (2004) 1.62
Comparative evolutionary analysis of olfactory receptor gene clusters between humans and mice. Gene (2005) 1.55
One hundred twenty years of koala retrovirus evolution determined from museum skins. Mol Biol Evol (2012) 1.51
Simulation study of the reliability and robustness of the statistical methods for detecting positive selection at single amino acid sites. Mol Biol Evol (2002) 1.50
Molecular evolution of the nontandemly repeated genes of the histone 3 multigene family. Mol Biol Evol (2002) 1.50
Evolutionary dynamics of olfactory receptor genes in Drosophila species. Proc Natl Acad Sci U S A (2007) 1.48
Evolutionary change of the numbers of homeobox genes in bilateral animals. Mol Biol Evol (2005) 1.37
Evolutionary changes of the number of olfactory receptor genes in the human and mouse lineages. Gene (2004) 1.32
Origins and evolution of microRNA genes in Drosophila species. Genome Biol Evol (2010) 1.31
Reanalysis of Murphy et al.'s data gives various mammalian phylogenies and suggests overcredibility of Bayesian trees. J Mol Evol (2003) 1.30
MHC, TSP, and the origin of species: from immunogenetics to evolutionary genetics. Annu Rev Genet (2007) 1.26
Antiquity and evolution of the MADS-box gene family controlling flower development in plants. Mol Biol Evol (2003) 1.24
Heterogeneous but conserved natural killer receptor gene complexes in four major orders of mammals. Proc Natl Acad Sci U S A (2006) 1.21
Empirical tests of the reliability of phylogenetic trees constructed with microsatellite DNA. Genetics (2008) 1.20
Origins and evolution of microRNA genes in plant species. Genome Biol Evol (2012) 1.20
Origin and evolution of influenza virus hemagglutinin genes. Mol Biol Evol (2002) 1.19
Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization. Proc Natl Acad Sci U S A (2008) 1.19
Concerted and nonconcerted evolution of the Hsp70 gene superfamily in two sibling species of nematodes. Mol Biol Evol (2003) 1.17
Phospholipase C-gamma: diverse roles in receptor-mediated calcium signaling. Trends Biochem Sci (2005) 1.13
Birth-and-death evolution in primate MHC class I genes: divergence time estimates. Mol Biol Evol (2003) 1.11
The origins and early evolution of DNA mismatch repair genes--multiple horizontal gene transfers and co-evolution. Nucleic Acids Res (2007) 1.10
Purifying selection and birth-and-death evolution in the histone H4 gene family. Mol Biol Evol (2002) 1.09
Evolutionary dynamics of the immunoglobulin heavy chain variable region genes in vertebrates. Immunogenetics (2008) 1.09
Rapid expansion of killer cell immunoglobulin-like receptor genes in primates and their coevolution with MHC Class I genes. Gene (2005) 1.09
Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm. Front Microbiol (2013) 1.06
Evolutionary redefinition of immunoglobulin light chain isotypes in tetrapods using molecular markers. Proc Natl Acad Sci U S A (2008) 1.05
Origins and evolution of the formin multigene family that is involved in the formation of actin filaments. Mol Biol Evol (2008) 1.03
Biochemical analysis of expansin-like proteins from microbes. Carbohydr Polym (2013) 1.03
Structure-function analysis of the bacterial expansin EXLX1. J Biol Chem (2011) 1.01
Ultraconserved coding regions outside the homeobox of mammalian Hox genes. BMC Evol Biol (2008) 0.98
Origin and evolution of the Ig-like domains present in mammalian leukocyte receptors: insights from chicken, frog, and fish homologues. Immunogenetics (2005) 0.98
Adaptive evolution of variable region genes encoding an unusual type of immunoglobulin in camelids. Mol Biol Evol (2002) 0.97
Genomic organization and evolutionary analysis of Ly49 genes encoding the rodent natural killer cell receptors: rapid evolution by repeated gene duplication. Immunogenetics (2004) 0.96
Origin and evolution of the chicken leukocyte receptor complex. Proc Natl Acad Sci U S A (2005) 0.95
TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion. J Biol Chem (2008) 0.92
The descent of the antibody-based immune system by gradual evolution. Proc Natl Acad Sci U S A (2004) 0.91
Pregabalin induced neutropenia. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.91
Bacterial expansins and related proteins from the world of microbes. Appl Microbiol Biotechnol (2015) 0.89
Evolutionary changes of the target sites of two microRNAs encoded in the Hox gene cluster of Drosophila and other insect species. Genome Biol Evol (2010) 0.88
Analysis of the immunoglobulin light chain genes in zebra finch: evolutionary implications. Mol Biol Evol (2010) 0.86
Genomic drift and evolution of microsatellite DNAs in human populations. Mol Biol Evol (2009) 0.85
Organization, alternative splicing, polymorphism, and phylogenetic position of lamprey CD45 gene. Immunogenetics (2005) 0.83
Identification of several cytoplasmic HSP70 genes from the Mediterranean mussel (Mytilus galloprovincialis) and their long-term evolution in Mollusca and Metazoa. J Mol Evol (2006) 0.82
Evolutionary genomics of immunoglobulin-encoding Loci in vertebrates. Curr Genomics (2012) 0.82
Genetic variation at hair length candidate genes in elephants and the extinct woolly mammoth. BMC Evol Biol (2009) 0.81
Comparative genomics and evolution of the alpha-defensin multigene family in primates. Mol Biol Evol (2010) 0.80
Comparative genomics and evolution of immunoglobulin-encoding loci in tetrapods. Adv Immunol (2011) 0.80
Olanzapine-induced leucopenia and neutropenia. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.80
A simple method for predicting the functional differentiation of duplicate genes and its application to MIKC-type MADS-box genes. Nucleic Acids Res (2005) 0.79
Eighty percent of proteins are different between humans and chimpanzees. Gene (2005) 0.79
Is positive selection responsible for the evolution of a duplicate UV-sensitive opsin gene in Heliconius butterflies? Proc Natl Acad Sci U S A (2010) 0.78
Evolution of the sex-lethal gene in insects and origin of the sex-determination system in Drosophila. J Mol Evol (2013) 0.78
Random fluctuation of selection coefficients and the extent of nucleotide variation in human populations. Proc Natl Acad Sci U S A (2013) 0.75
Urinary hesitancy and retention caused by ziprasidone. Int Clin Psychopharmacol (2006) 0.75