Published in J Cell Biochem on September 01, 2009
Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol (2012) 1.93
Host-pathogen interactions made transparent with the zebrafish model. Curr Drug Targets (2011) 1.60
Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol (2012) 1.32
Zebrafish as a model for normal and malignant hematopoiesis. Dis Model Mech (2011) 1.28
Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development. Development (2012) 1.22
Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. J Exp Med (2015) 1.09
Platelets: covert regulators of lymphatic development. Arterioscler Thromb Vasc Biol (2010) 1.06
Understanding vascular development. Wiley Interdiscip Rev Dev Biol (2012) 1.02
Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model. Breast Cancer Res (2013) 1.02
Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries. Adv Hematol (2012) 1.01
The negative impact of Wnt signaling on megakaryocyte and primitive erythroid progenitors derived from human embryonic stem cells. Stem Cell Res (2013) 0.94
Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols. Proc Natl Acad Sci U S A (2012) 0.92
Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5. Oncotarget (2013) 0.91
Hematopoiesis. Cold Spring Harb Perspect Biol (2012) 0.91
Differential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish. PLoS One (2015) 0.88
Cell signaling pathways involved in hematopoietic stem cell specification. Exp Cell Res (2014) 0.84
Haematopoiesis in the head kidney of common carp (Cyprinus carpio L.): a morphological study. Fish Physiol Biochem (2010) 0.84
Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells. Proc Natl Acad Sci U S A (2016) 0.84
How mitochondrial dysfunction affects zebrafish development and cardiovascular function: an in vivo model for testing mitochondria-targeted drugs. Br J Pharmacol (2013) 0.83
Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model. Genome Med (2011) 0.83
Ginger stimulates hematopoiesis via Bmp pathway in zebrafish. PLoS One (2012) 0.83
Novel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish models. Adv Hematol (2012) 0.80
Small zebrafish in a big chemical pond. J Cell Biochem (2012) 0.79
Zebrafish hoxd4a acts upstream of meis1.1 to direct vasculogenesis, angiogenesis and hematopoiesis. PLoS One (2013) 0.78
Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish. J Hematol Oncol (2014) 0.78
Methionine aminopeptidase 2 is required for HSC initiation and proliferation. Blood (2011) 0.78
Zebrafish scube1 (signal peptide-CUB (complement protein C1r/C1s, Uegf, and Bmp1)-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis. J Biol Chem (2012) 0.78
CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. J Exp Med (2017) 0.78
Optimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolites. PLoS One (2013) 0.77
Biology of Bony Fish Macrophages. Biology (Basel) (2015) 0.77
Zebrafish as a model for leukemia and other hematopoietic disorders. J Hematol Oncol (2015) 0.77
HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation. Exp Hematol (2016) 0.76
In vivo chemical screening for modulators of hematopoiesis and hematological diseases. Adv Hematol (2012) 0.76
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin. BioDrugs (2015) 0.76
Characterization of a weak allele of zebrafish cloche mutant. PLoS One (2011) 0.76
mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in haematopoietic tissues. Br J Haematol (2010) 0.76
Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis. Sci Rep (2016) 0.75
Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence. EMBO J (2016) 0.75
Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis. Sci Rep (2016) 0.75
TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. PLoS Genet (2015) 0.75
Znf45l affects primitive hematopoiesis by regulating transforming growth factor-β signaling. BMB Rep (2014) 0.75
Intronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemia. Sci Rep (2016) 0.75
Cyp2aa9 regulates haematopoietic stem cell development in zebrafish. Sci Rep (2016) 0.75
Hematopoiesis: an evolving paradigm for stem cell biology. Cell (2008) 11.95
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature (2007) 7.55
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol (2003) 5.73
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab (2005) 5.32
Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell (2008) 5.09
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell (2009) 4.69
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (2010) 4.37
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proc Natl Acad Sci U S A (2005) 4.15
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell (2012) 4.04
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol (2005) 3.68
Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. Nat Genet (2005) 3.66
Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes Dev (2007) 3.45
Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE). Nat Biotechnol (2008) 3.43
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature (2011) 3.37
Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev (2005) 3.27
Myc-induced T cell leukemia in transgenic zebrafish. Science (2003) 3.15
The use of zebrafish to understand immunity. Immunity (2004) 3.09
Mitoferrin is essential for erythroid iron assimilation. Nature (2006) 2.99
SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Mol Cell (2002) 2.93
Hematopoietic stem cell development is dependent on blood flow. Cell (2009) 2.77
Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood (2005) 2.65
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell Stem Cell (2007) 2.56
The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene (2004) 2.54
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell (2011) 2.53
Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood (2004) 2.46
TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell (2010) 2.33
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature (2005) 2.25
DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature (2011) 2.23
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc Natl Acad Sci U S A (2005) 2.19
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell (2008) 2.17
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature (2003) 2.16
Mutant-specific gene programs in the zebrafish. Blood (2005) 2.15
Zebrafish as a cancer model system. Cancer Cell (2002) 2.12
Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Dev Cell (2005) 2.12
Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (2011) 2.11
An Mll-dependent Hox program drives hematopoietic progenitor expansion. Curr Biol (2004) 2.10
Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell (2011) 2.04
Use of the zebrafish system to study primitive and definitive hematopoiesis. Annu Rev Genet (2005) 2.02
Hooked! Modeling human disease in zebrafish. J Clin Invest (2012) 2.00
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell (2012) 1.96
The zebrafish as a model organism to study development of the immune system. Adv Immunol (2003) 1.96
Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Dev Biol (2005) 1.93
Hematopoiesis and stem cells: plasticity versus developmental heterogeneity. Nat Immunol (2002) 1.90
APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Dev Biol (2008) 1.90
Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors. Nat Methods (2007) 1.90
Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nat Chem Biol (2005) 1.87
T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell (2010) 1.85
In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proc Natl Acad Sci U S A (2004) 1.85
SUMO-1 protease-1 regulates gene transcription through PML. Mol Cell (2002) 1.80
The clinical potential of stem cells. Curr Opin Cell Biol (2004) 1.73
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood (2013) 1.72
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell (2012) 1.71
Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proc Natl Acad Sci U S A (2007) 1.70
Resolving the controversy about N-cadherin and hematopoietic stem cells. Cell Stem Cell (2010) 1.70
Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Dev Biol (2002) 1.70
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell (2013) 1.68
Organogenesis--heart and blood formation from the zebrafish point of view. Science (2002) 1.67
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol (2004) 1.64
The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome Biol (2013) 1.54
Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron (2007) 1.52
Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Curr Top Dev Biol (2003) 1.51
A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chem Biol Drug Des (2006) 1.50
The pu.1 promoter drives myeloid gene expression in zebrafish. Blood (2004) 1.49
The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization. Mol Cell Biol (2007) 1.47
Definition of the zebrafish genome using flow cytometry and cytogenetic mapping. BMC Genomics (2007) 1.46
Cancer genetics and drug discovery in the zebrafish. Nat Rev Cancer (2003) 1.45
Zebrafish scl functions independently in hematopoietic and endothelial development. Dev Biol (2005) 1.45
Hematopoietic development in the zebrafish. Int J Dev Biol (2010) 1.44
The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development (2003) 1.43
Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet (2003) 1.40
Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood (2007) 1.39
The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Dev Biol (2006) 1.39
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood (2010) 1.34
Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol (2012) 1.32
Melanocytes in development, regeneration, and cancer. Cell Stem Cell (2008) 1.31
Hematopoietic gene expression profile in zebrafish kidney marrow. Proc Natl Acad Sci U S A (2004) 1.31
New waves of discovery: modeling cancer in zebrafish. J Clin Oncol (2007) 1.31
The Zon laboratory guide to positional cloning in zebrafish. Methods Cell Biol (2004) 1.30
The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Hum Mol Genet (2011) 1.30
AlphaA-crystallin expression prevents gamma-crystallin insolubility and cataract formation in the zebrafish cloche mutant lens. Development (2006) 1.28
Zebrafish as a model for normal and malignant hematopoiesis. Dis Model Mech (2011) 1.28
Ferroportin1 is required for normal iron cycling in zebrafish. J Clin Invest (2005) 1.27
A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood (2009) 1.27
Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proc Natl Acad Sci U S A (2007) 1.24
The zebrafish spi1 promoter drives myeloid-specific expression in stable transgenic fish. Blood (2003) 1.24
Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish. Zebrafish (2009) 1.24
Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a. PLoS Genet (2007) 1.24
A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes Dev (2007) 1.23
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proc Natl Acad Sci U S A (2010) 1.21
The zebrafish runzel muscular dystrophy is linked to the titin gene. Dev Biol (2007) 1.20
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proc Natl Acad Sci U S A (2006) 1.19
Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood (2009) 1.19
The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood (2002) 1.16
Swimming into the future of drug discovery: in vivo chemical screens in zebrafish. ACS Chem Biol (2010) 1.16
Melanocytes in development and cancer. J Cell Physiol (2010) 1.15
Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proc Natl Acad Sci U S A (2012) 1.14
Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish. Development (2002) 1.14
SnapShot: hematopoiesis. Cell (2008) 1.14
A critical role for calponin 2 in vascular development. J Biol Chem (2005) 1.14