Curcumin inhibits pro-inflammatory mediators and metalloproteinase-3 production by chondrocytes.

PubWeight™: 1.00‹?› | Rank: Top 15%

🔗 View Article (PMID 19579007)

Published in Inflamm Res on July 05, 2009

Authors

M Mathy-Hartert1, I Jacquemond-Collet, F Priem, C Sanchez, C Lambert, Y Henrotin

Author Affiliations

1: Institute of Pathology, CHU Sart-Tilman, Liège, Belgium. mmathy@ulg.ac.be

Articles citing this

Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers. Br J Pharmacol (2013) 1.21

Potent anti-inflammatory effects of systemically administered curcumin modulate periodontal disease in vivo. J Periodontal Res (2011) 1.01

Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management. Springerplus (2013) 0.95

Current nutraceuticals in the management of osteoarthritis: a review. Ther Adv Musculoskelet Dis (2012) 0.94

Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis. Inflamm Res (2010) 0.93

Curcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitro. Genes Nutr (2010) 0.91

Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health. Int J Mol Sci (2012) 0.90

Nutraceuticals: potential for chondroprotection and molecular targeting of osteoarthritis. Int J Mol Sci (2013) 0.88

Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study. J Orthop Sci (2014) 0.88

Pharmacologic approaches to the aging athlete. Sports Health (2014) 0.82

Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis. Drug Des Devel Ther (2015) 0.81

Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model. Arthritis Res Ther (2016) 0.80

Cordycepin modulates inflammatory and catabolic gene expression in interleukin-1beta-induced human chondrocytes from advanced-stage osteoarthritis: an in vitro study. Int J Clin Exp Pathol (2014) 0.79

Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer. PLoS One (2015) 0.79

Comparative evaluation of the efficacy of curcumin gel with and without photo activation as an adjunct to scaling and root planing in the treatment of chronic periodontitis: A split mouth clinical and microbiological study. J Nat Sci Biol Med (2015) 0.78

UP1304, a Botanical Composition Containing Two Standardized Extracts of Curcuma longa and Morus alba, Mitigates Pain and Inflammation in Adjuvant-induced Arthritic Rats. Pharmacognosy Res (2016) 0.78

Therapeutic actions of curcumin in bone disorders. Bonekey Rep (2016) 0.77

The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis. Drug Des Devel Ther (2016) 0.76

Recent Advances in Nanoparticle-Mediated Delivery of Anti-Inflammatory Phytocompounds. Int J Mol Sci (2017) 0.75

Curcumin Inhibits Apoptosis of Chondrocytes through Activation ERK1/2 Signaling Pathways Induced Autophagy. Nutrients (2017) 0.75

Identification of Targets of a New Nutritional Mixture for Osteoarthritis Management Composed by Curcuminoids Extract, Hydrolyzed Collagen and Green Tea Extract. PLoS One (2016) 0.75

Articles cited by this

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem (1982) 27.26

A simple, rapid, and sensitive DNA assay procedure. Anal Biochem (1980) 23.88

OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage (2008) 10.99

Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res (2001) 5.78

Curcumin as "Curecumin": from kitchen to clinic. Biochem Pharmacol (2007) 5.13

A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J Immunol Methods (1988) 4.70

Curcumin: the story so far. Eur J Cancer (2005) 4.17

"Spicing up" of the immune system by curcumin. J Clin Immunol (2007) 2.43

Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol Biomarkers Prev (2002) 2.26

Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production. Cancer Res (2001) 2.05

Oxygen and reactive oxygen species in cartilage degradation: friends or foes? Osteoarthritis Cartilage (2005) 1.93

Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes. Matrix Biol (2002) 1.88

Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes. Exp Cell Res (2003) 1.79

Preliminary study on antirheumatic activity of curcumin (diferuloyl methane). Indian J Med Res (1980) 1.74

Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis. Biochem Pharmacol (2007) 1.73

Culture and growth characteristics of chondrocytes encapsulated in alginate beads. Connect Tissue Res (1989) 1.65

Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun (1995) 1.62

Comparison between chondroprotective effects of glucosamine, curcumin, and diacerein in IL-1beta-stimulated C-28/I2 chondrocytes. Osteoarthritis Cartilage (2008) 1.62

Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages. Biochem Pharmacol (2000) 1.48

Prostaglandin E2 exerts catabolic effects in osteoarthritis cartilage: evidence for signaling via the EP4 receptor. J Immunol (2008) 1.45

Interleukin-6 modulates production of T lymphocyte-derived cytokines in antigen-induced arthritis and drives inflammation-induced osteoclastogenesis. Arthritis Rheum (2006) 1.42

Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes. Am J Physiol Gastrointest Liver Physiol (2002) 1.34

Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown. Arthritis Rheum (2001) 1.31

Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis. J Nat Prod (2006) 1.30

Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis. Cytokines Cell Mol Ther (2000) 1.27

The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis. Inflamm Res (2006) 1.18

IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage. Matrix Biol (2000) 1.16

Involvement of IL-6, apart from its role in immunity, in mediating a chronic response during experimental arthritis. Am J Pathol (2000) 1.14

Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway. J Immunol (2001) 1.12

Imbalance between the mechanisms of activation and inhibition of metalloproteases in the early lesions of experimental osteoarthritis. Arthritis Rheum (1990) 1.10

Strontium ranelate increases cartilage matrix formation. J Bone Miner Res (2001) 1.08

Role of metalloproteinases in human osteoarthritis. J Rheumatol Suppl (1991) 1.04

Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study. Ann Anat (2005) 1.02

Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression. Inflamm Res (2008) 0.99

Antioxidant to treat osteoarthritis: dream or reality? Curr Drug Targets (2007) 0.98

Effects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytes. Ann N Y Acad Sci (2004) 0.98

Neutrophil accumulation and activation by homologous IL-8 in rabbits. IL-8 induces destruction of cartilage and production of IL-1 and IL-1 receptor antagonist in vivo. J Immunol (1995) 0.95

Role of eicosanoids in structural degradation in osteoarthritis. Curr Opin Rheumatol (2003) 0.89

Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs. J Rheumatol (2002) 0.88

Equine postanaesthetic myositis: thromboxanes, prostacyclin and prostaglandin E2 production. Vet Res Commun (1988) 0.78

Articles by these authors

Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet (2001) 9.02

Response by women aged 65-79 to invitation for screening for breast cancer by mammography: a pilot study. BMJ (1990) 2.51

OARSI recommended performance-based tests to assess physical function in people diagnosed with hip or knee osteoarthritis. Osteoarthritis Cartilage (2013) 2.49

Molecular genetic evidence of bacterial colonization of cholesterol gallstones. Gastroenterology (1995) 2.45

Chapter 2. European guidelines for prevention in low back pain : November 2004. Eur Spine J (2006) 2.31

Probing essential oil biosynthesis and secretion by functional evaluation of expressed sequence tags from mint glandular trichomes. Proc Natl Acad Sci U S A (2000) 2.19

The Old English Medical Vocabulary: (Section of the History of Medicine). Proc R Soc Med (1940) 2.09

Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis. Osteoarthritis Cartilage (2011) 1.89

Simple DNA extraction method for dried blood spots and comparison of two PCR assays for diagnosis of vertical human immunodeficiency virus type 1 transmission in Rwanda. J Clin Microbiol (2004) 1.77

Characterization of regulatory functions of the varicella-zoster virus gene 63-encoded protein. J Virol (1992) 1.68

Roseobacter gallaeciensis sp. nov., a new marine bacterium isolated from rearings and collectors of the scallop Pecten maximus. Int J Syst Bacteriol (1998) 1.57

Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription. Mol Cell (2001) 1.56

Decreased oxidative stress in patients with idiopathic dilated cardiomyopathy one year after immunoglobulin adsorption. J Am Coll Cardiol (2001) 1.55

An inhibitor of the toxicity of tumour necrosis factor in the serum of patients with sarcoidosis, tuberculosis and Crohn's disease. Clin Exp Immunol (1990) 1.53

Conserved interaction between distinct Krüppel-associated box domains and the transcriptional intermediary factor 1 beta. Proc Natl Acad Sci U S A (2001) 1.50

Soft-chemistry-based routes to epitaxial α-quartz thin films with tunable textures. Science (2013) 1.49

Efficacy of propafenone in preventing ventricular tachycardia: inverse correlation with rate-related prolongation of conduction time. J Am Coll Cardiol (1990) 1.40

Observation of B(0)(s)-->Psi(2S)Phi and measurement of the ratio of branching fractions Beta(B(0)(s)-->Psi(2S)Phi)/Beta(B(0)(s)-->J/PsiPhi). Phys Rev Lett (2006) 1.40

How to prevent low back pain. Best Pract Res Clin Rheumatol (2005) 1.38

In vitro assays of chondrocyte functions: the influence of drugs and hormones. Scand J Rheumatol Suppl (1990) 1.38

Attenuated signature-tagged mutagenesis mutants of Brucella melitensis identified during the acute phase of infection in mice. Infect Immun (2003) 1.38

Coronavirus derived expression systems. J Biotechnol (2001) 1.32

Diagnostic sensitivity of serum cystatin for impaired glomerular filtration rate. Pediatr Nephrol (1999) 1.32

An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin. Br J Clin Pharmacol (1988) 1.29

High sensitivity and specificity of serum procalcitonin levels in adults with bacterial meningitis. Clin Infect Dis (1999) 1.28

The role of oil and agalactosyl IgG in the induction of arthritis in rodent models. Eur J Immunol (1991) 1.25

Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart. Proc Natl Acad Sci U S A (1997) 1.25

Role of the mitochondrial DNA 16184-16193 poly-C tract in type 2 diabetes. Lancet (2005) 1.24

Emerging standards for diabetes care from a city-wide primary care audit. Diabet Med (1994) 1.24

Use of laser microdissection greatly improves the recovery of DNA from sperm on microscope slides. Forensic Sci Int (2003) 1.23

Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus type 1 drug resistance mutations in patients failing highly active antiretroviral therapy. J Clin Microbiol (2001) 1.22

Serum and ascitic procalcitonin levels in cirrhotic patients with spontaneous bacterial peritonitis: diagnostic value and relationship to pro-inflammatory cytokines. Intensive Care Med (2000) 1.19

Uptake of glutamate in Corynebacterium glutamicum. 1. Kinetic properties and regulation by internal pH and potassium. Eur J Biochem (1990) 1.18

[Breast carcinoma metastasis in ileum-colon and gallbladder simulating inflammatory diseases]. Rev Fac Cien Med Univ Nac Cordoba (1999) 1.13

Effects of endothelin receptor antagonists on the progression of diabetic nephropathy. Nephron (2001) 1.12

Residual renal function in a large cohort of peritoneal dialysis patients: change over time, impact on mortality and nutrition. Perit Dial Int (2001) 1.11

Uptake of glutamate in Corynebacterium glutamicum. 2. Evidence for a primary active transport system. Eur J Biochem (1990) 1.09

Preventive dental behavior of urban mothers. J Health Hum Behav (1965) 1.07

Stigmasterol: a phytosterol with potential anti-osteoarthritic properties. Osteoarthritis Cartilage (2009) 1.06

Interleukin-1beta and interleukin-6 disturb the antioxidant enzyme system in bovine chondrocytes: a possible explanation for oxidative stress generation. Osteoarthritis Cartilage (2008) 1.06

Subchondral tibial bone mineral density predicts future joint space narrowing at the medial femoro-tibial compartment in patients with knee osteoarthritis. Bone (2003) 1.05

Stress-induced signaling pathways in hyalin chondrocytes: inhibition by Avocado-Soybean Unsaponifiables (ASU). Osteoarthritis Cartilage (2007) 1.05

Osteoarthritic patients with high cartilage turnover show increased responsiveness to the cartilage protecting effects of glucosamine sulphate. Clin Exp Rheumatol (2004) 1.05

Serum cytokine changes in systemic vasculitis. Immunology (1989) 1.05

Adaptations to swimming training: influence of training volume. Med Sci Sports Exerc (1991) 1.04

Tissue distribution and bioactivity of amphotericin B administered in liposomes to cancer patients. J Antimicrob Chemother (1991) 1.04

High incidence of adeno- and polyomavirus-induced hemorrhagic cystitis in bone marrow allotransplantation for hematological malignancy following T cell depletion and cyclosporine. Bone Marrow Transplant (1998) 1.04

Peritoneal dialysis in liver disorders. Perit Dial Int (1996) 1.03

Nutraceuticals: do they represent a new era in the management of osteoarthritis? - a narrative review from the lessons taken with five products. Osteoarthritis Cartilage (2010) 1.03

Measurement of d sigma/dM and forward-backward charge asymmetry for high-mass Drell-Yan e(+)e(-) pairs from pp macro collisions at square root of s = 1.8 TeV. Phys Rev Lett (2001) 1.02

Efflux of compatible solutes in Corynebacterium glutamicum mediated by osmoregulated channel activity. Eur J Biochem (1997) 1.01

Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model. Br J Pharmacol (2008) 1.01

Relationship between conformational stability and lyophilization-induced structural changes in chymotrypsin. Biotechnol Appl Biochem (2000) 1.01

Structure and technofunctional properties of protein-polysaccharide complexes: a review. Crit Rev Food Sci Nutr (1998) 1.01

Sleep and circadian phase characteristics of adolescent and young adult males in a naturalistic summertime condition. Chronobiol Int (2000) 1.00

Reactive oxygen species downregulate the expression of pro-inflammatory genes by human chondrocytes. Inflamm Res (2003) 1.00

Variability in GWAS analysis: the impact of genotype calling algorithm inconsistencies. Pharmacogenomics J (2010) 1.00

Bone resorption in post-menopausal women with normal and low BMD assessed with biochemical markers specific for telopeptide derived degradation products of collagen type I. Calcif Tissue Int (2001) 1.00

Conditions that affect sleep alter the expression of molecules associated with synaptic plasticity. Am J Physiol Regul Integr Comp Physiol (2001) 0.98

Episodic ataxia and hemiplegia caused by the 8993T->C mitochondrial DNA mutation. J Med Genet (2007) 0.98

Columbian field epidemiology training program. Am J Public Health (1998) 0.98

Olanzapine-induced elevation of plasma triglyceride levels. Am J Psychiatry (1999) 0.97

Longitudinal follow-up of nutritional status and its influencing factors in adults undergoing allogeneic hematopoietic cell transplantation. Bone Marrow Transplant (2012) 0.97

Are cystatin C and beta 2-microglobulin better markers than serum creatinine for prediction of a normal glomerular filtration rate in pediatric subjects? Clin Chem (1997) 0.96

One-year follow-up of Coll2-1, Coll2-1NO2 and myeloperoxydase serum levels in osteoarthritis patients after hip or knee replacement. Ann Rheum Dis (2007) 0.96

Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes. Arthritis Rheum (2004) 0.96

In-vitro activity of SCH39304 in comparison with amphotericin B and fluconazole. J Antimicrob Chemother (1990) 0.95

JunD is involved in the antiproliferative effect of Delta9-tetrahydrocannabinol on human breast cancer cells. Oncogene (2008) 0.95

Time dependent changes in the concentration and type of bacterial sequences found in cholesterol gallstones. Hepatology (1998) 0.95

The role of physiotherapy after total knee arthroplasty in patients with haemophilia. Haemophilia (2008) 0.95

EfficientAgrobacterium-mediated transformation and recovery of transgenic plants from pear (Pyrus communis L.). Plant Cell Rep (1996) 0.94

Measurement of the strong coupling constant from inclusive jet production at the Tevatron pp collider. Phys Rev Lett (2002) 0.94

Relationship between semen quality and the seminal plasma components carnitine, alpha-glucosidase, fructose, citrate and granulocyte elastase in infertile men compared with a normal population. Hum Reprod (2000) 0.94

The expression of G250/mn/CA9 antigen by flow cytometry: its possible implication for detection of micrometastatic renal cancer cells. Clin Cancer Res (2001) 0.94

Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells. Eur J Biochem (1985) 0.94

Symptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. A double blind, prospective, placebo-controlled study. Scand J Rheumatol (2001) 0.94

First hemodialysis access selection varies with patient acuity. Adv Ren Replace Ther (2000) 0.94

A comparative study of the formation of chemically reactive drug metabolites by human liver microsomes. Br J Clin Pharmacol (1988) 0.94

Triggering Glutamate Excretion in Corynebacterium glutamicum by Modulating the Membrane State with Local Anesthetics and Osmotic Gradients. Appl Environ Microbiol (1995) 0.94

Mitochondrial DNA haplogroups and serum levels of proteolytic enzymes in patients with osteoarthritis. Ann Rheum Dis (2010) 0.94

Antiviral efficacy and resistance in patients on antiretroviral therapy in Kigali, Rwanda: the real-life situation in 2002. HIV Med (2006) 0.93

The biosynthetic gene cluster for the anticancer drug bleomycin from Streptomyces verticillus ATCC15003 as a model for hybrid peptide-polyketide natural product biosynthesis. J Ind Microbiol Biotechnol (2001) 0.93

Reduction in PINP, a marker of bone metabolism, with raloxifene treatment and its relationship with vertebral fracture risk. Bone (2004) 0.93

Collagen fibril disruption occurs early in primary guinea pig knee osteoarthritis. Osteoarthritis Cartilage (2009) 0.93

Genetic analysis of the Serratia marcescens N28b O4 antigen gene cluster. J Bacteriol (1999) 0.93

Search for gluinos and scalar quarks in pp collisions at square root[s] = 1.8 TeV using the missing energy plus multijets signature. Phys Rev Lett (2002) 0.93

Assessment of variability in GWAS with CRLMM genotyping algorithm on WTCCC coronary artery disease. Pharmacogenomics J (2010) 0.93

Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway. Circulation (2001) 0.91

In-vitro activity of cilofungin (LY121019) in comparison with amphotericin B. J Antimicrob Chemother (1989) 0.91

The development of monoclonal antibodies to the human mitochondrial 60-kd heat-shock protein, and their use in studying the expression of the protein in rheumatoid arthritis. Arthritis Rheum (1992) 0.91

Genotypic correlates of resistance to HIV-1 protease inhibitors on longitudinal data: the role of secondary mutations. Antivir Ther (2001) 0.91

Altered expression of angiogenesis and lymphangiogenesis markers in the uninvolved skin of plaque-type psoriasis. Br J Dermatol (2008) 0.91

In-vitro evaluation of drugs proposed as chondroprotective agents. Int J Tissue React (1992) 0.90

Schmallenberg virus cases identified in Ireland. Vet Rec (2012) 0.90

Search for Z' --> e+ e- using dielectron mass and angular distribution. Phys Rev Lett (2006) 0.90

Results of a collaborative study of the EDNAP group regarding mitochondrial DNA heteroplasmy and segregation in hair shafts. Forensic Sci Int (2004) 0.90

Variant human immunodeficiency virus type 1 proteases and response to combination therapy including a protease inhibitor. Antimicrob Agents Chemother (2001) 0.90

Mitochondrial DNA haplogroups modulate the serum levels of biomarkers in patients with osteoarthritis. Ann Rheum Dis (2009) 0.90