Published in Mol Biosyst on June 19, 2009
On guanidinium and cellular uptake. J Org Chem (2014) 0.79
Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell (2012) 3.50
Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides. Proc Natl Acad Sci U S A (2005) 2.83
A high-throughput screen for compounds that inhibit aggregation of the Alzheimer's peptide. ACS Chem Biol (2006) 2.09
Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation. Immunity (2009) 2.00
Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase. Curr Biol (2002) 1.69
Identification of a novel protein regulating microtubule stability through a chemical approach. Chem Biol (2004) 1.64
RNA-selective, live cell imaging probes for studying nuclear structure and function. Chem Biol (2006) 1.63
A single-cell analysis of myogenic dedifferentiation induced by small molecules. Chem Biol (2005) 1.63
Dissection of melanogenesis with small molecules identifies prohibitin as a regulator. Chem Biol (2005) 1.48
Novel orthogonal strategy toward solid-phase synthesis of 1,3,5-substituted triazines. Org Lett (2003) 1.46
Triazine-based tyrosinase inhibitors identified by chemical genetic screening. Pigment Cell Res (2005) 1.40
Chemical genetics. Chem Rev (2006) 1.37
Cartoon distraction alleviates anxiety in children during induction of anesthesia. Anesth Analg (2012) 1.28
Combinatorial strategies in fluorescent probe development. Chem Rev (2012) 1.28
Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression. Cell Metab (2005) 1.23
Small molecule microarrays: recent advances and applications. Curr Opin Chem Biol (2005) 1.22
Forward chemical genetic approach identifies new role for GAPDH in insulin signaling. Nat Chem Biol (2006) 1.19
Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer detection. Angew Chem Int Ed Engl (2011) 1.18
Identification of radiation-specific responses from gene expression profile. Oncogene (2002) 1.16
Identification of a new class of prostaglandin transporter inhibitors and characterization of their biological effects on prostaglandin E2 transport. J Pharmacol Exp Ther (2005) 1.10
Surface-enhanced Raman scattering in cancer detection and imaging. Trends Biotechnol (2013) 1.09
Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening. J Am Chem Soc (2003) 1.07
Combinatorial rosamine library and application to in vivo glutathione probe. J Am Chem Soc (2007) 1.06
A chemical screen identifies novel compounds that overcome glial-mediated inhibition of neuronal regeneration. J Neurosci (2010) 1.05
Discovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility. Protein Sci (2009) 1.03
Development of photostable near-infrared cyanine dyes. Chem Commun (Camb) (2010) 1.01
A fluorescent rosamine compound selectively stains pluripotent stem cells. Angew Chem Int Ed Engl (2010) 1.01
Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem (2002) 1.01
Colorimetric identification of carbohydrates by a pH indicator/pH change inducer ensemble. Angew Chem Int Ed Engl (2006) 1.00
Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters. Chem Commun (Camb) (2011) 0.99
A novel zebrafish human tumor xenograft model validated for anti-cancer drug screening. Mol Biosyst (2012) 0.99
Novel use of fluorescent glucose analogues to identify a new class of triazine-based insulin mimetics possessing useful secondary effects. Mol Biosyst (2010) 0.98
Tools for target identification and validation. Curr Opin Chem Biol (2004) 0.98
Structural and functional modeling of human lysozyme reveals a unique nonapeptide, HL9, with anti-HIV activity. Biochemistry (2005) 0.97
Diversity-oriented optical imaging probe development. Curr Opin Chem Biol (2011) 0.96
Embryonic and induced pluripotent stem cell staining and sorting with the live-cell fluorescence imaging probe CDy1. Nat Protoc (2011) 0.96
Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1. Am J Hematol (2013) 0.96
Combinatorial approach to organelle-targeted fluorescent library based on the styryl scaffold. J Am Chem Soc (2003) 0.95
Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries. J Comb Chem (2007) 0.95
Intracellular glutathione detection using MnO(2)-nanosheet-modified upconversion nanoparticles. J Am Chem Soc (2011) 0.95
Establishment of a robust dengue virus NS3-NS5 binding assay for identification of protein-protein interaction inhibitors. Antiviral Res (2012) 0.95
Synthesis and anticancer activity studies of cyclopamine derivatives. Bioorg Med Chem Lett (2008) 0.95
Development of biocompatible SERS nanotag with increased stability by chemisorption of reporter molecule for in vivo cancer detection. Biosens Bioelectron (2010) 0.94
Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. Biochem Biophys Res Commun (2003) 0.94
Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells. Cancer Lett (2007) 0.94
Regulation of p53 by activated protein kinase C-delta during nitric oxide-induced dopaminergic cell death. J Biol Chem (2005) 0.93
Microarrays of tagged combinatorial triazine libraries in the discovery of small-molecule ligands of human IgG. J Comb Chem (2004) 0.93
A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. J Am Chem Soc (2002) 0.93
Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents. PLoS One (2010) 0.93
Diversity-oriented fluorescence library approaches for probe discovery and development. Curr Opin Chem Biol (2010) 0.93
Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1. J Biol Chem (2006) 0.93
Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2. J Biol Chem (2004) 0.92
Neural stem cell specific fluorescent chemical probe binding to FABP7. Proc Natl Acad Sci U S A (2012) 0.92
Diversity-oriented fluorescence library approach for the discovery of sensors and probes. Mol Biosyst (2009) 0.92
Guanidine-containing molecular transporters: sorbitol-based transporters show high intracellular selectivity toward mitochondria. Angew Chem Int Ed Engl (2007) 0.91
Phytic acid synthesis and vacuolar accumulation in suspension-cultured cells of Catharanthus roseus induced by high concentration of inorganic phosphate and cations. Plant Physiol (2005) 0.90
Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening. J Am Chem Soc (2008) 0.90
Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor. Chem Commun (Camb) (2011) 0.90
Diversity-driven chemical probe development for biomolecules: beyond hypothesis-driven approach. Chem Soc Rev (2011) 0.90
Investigations of the molecular mechanism of metal-induced Abeta (1-40) amyloidogenesis. Biochemistry (2007) 0.89
Styryl-based compounds as potential in vivo imaging agents for beta-amyloid plaques. Chembiochem (2007) 0.89
Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors. Chem Biol (2002) 0.89
Accelerating fluorescent sensor discovery: unbiased screening of a diversity-oriented BODIPY library. Chem Commun (Camb) (2010) 0.88
Synthesis of all stereoisomers of KRN7000, the CD1d-binding NKT cell ligand. Bioorg Med Chem Lett (2008) 0.88
Synthesis of a BODIPY library and its application to the development of live cell glucagon imaging probe. J Am Chem Soc (2009) 0.88
A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids. J Am Chem Soc (2011) 0.88
Syntheses of sphingosine-1-phosphate analogues and their interaction with EDG/S1P receptors. Bioorg Med Chem Lett (2004) 0.88
Solid-phase synthesis of styryl dyes and their application as amyloid sensors. Angew Chem Int Ed Engl (2004) 0.87
High-content live cell imaging with RNA probes: advancements in high-throughput antimalarial drug discovery. BMC Cell Biol (2009) 0.87
Development of a high-affinity inhibitor of the prostaglandin transporter. J Pharmacol Exp Ther (2011) 0.86
A unique small molecule inhibitor of enolase clarifies its role in fundamental biological processes. ACS Chem Biol (2013) 0.86
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. fusion [corrected] inhibition. Biochem Biophys Res Commun (2007) 0.86
Elimination of a hydroxyl group in FTY720 dramatically improves the phosphorylation rate. Mol Pharmacol (2010) 0.86
The preanesthetic interview by anesthesiology residents: analysis of time and content. Korean J Anesthesiol (2012) 0.86
The role of "disaggregation" in optical probe development. Chem Soc Rev (2014) 0.86
Diversity oriented fluorescence library approach (DOFLA) for live cell imaging probe development. Acc Chem Res (2014) 0.86
Combinatorial synthesis of benzimidazolium dyes and its diversity directed application toward GTP-selective fluorescent chemosensors. J Am Chem Soc (2006) 0.84
The synthesis and biological characterization of a ceramide library. J Am Chem Soc (2002) 0.84
Design, synthesis, and delivery properties of novel guanidine-containing molecular transporters built on dimeric inositol scaffolds. Chemistry (2007) 0.84
Development of novel cell-permeable DNA sensitive dyes using combinatorial synthesis and cell-based screening. Chem Commun (Camb) (2003) 0.84
A photostable near-infrared protein labeling dye for in vivo imaging. Chem Asian J (2011) 0.84
Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish. Mol Biosyst (2005) 0.84
Structure-activity relationships of dimethylsphingosine (DMS) derivatives and their effects on intracellular pH and Ca2+ in the U937 monocyte cell line. Arch Pharm Res (2006) 0.84
A macrophage-specific fluorescent probe for intraoperative lymph node staging. Cancer Res (2013) 0.83
Styryl-based and tricyclic compounds as potential anti-prion agents. PLoS One (2011) 0.83
Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging. Org Biomol Chem (2011) 0.83
Tagged small molecule library approach for facilitated chemical genetics. Acc Chem Res (2007) 0.83
Tagged library approach facilitates forward chemical genetics. Mol Biosyst (2007) 0.83
Design, synthesis, and membrane-translocation studies of inositol-based transporters. Angew Chem Int Ed Engl (2006) 0.83
In situ investigation of mammalian inorganic polyphosphate localization using novel selective fluorescent probes JC-D7 and JC-D8. ACS Chem Biol (2014) 0.82
Divergent syntheses of all stereoisomers of phytosphingosine and their use in the construction of a ceramide library. Bioorg Chem (2008) 0.82
Tagged library approach to chemical genomics and proteomics. Curr Opin Chem Biol (2004) 0.82
Vaccinia-related kinase 2 mediates accumulation of polyglutamine aggregates via negative regulation of the chaperonin TRiC. Mol Cell Biol (2013) 0.82
Inhibitory effect of Hsp70 on angiotensin II-induced vascular smooth muscle cell hypertrophy. Exp Mol Med (2006) 0.82