Published in J Gene Med on October 01, 2009
Manufacture of tumor- and virus-specific T lymphocytes for adoptive cell therapies. Cancer Gene Ther (2015) 0.97
Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII. BMC Biotechnol (2011) 0.92
Efficient large volume lentiviral vector production using flow electroporation. Hum Gene Ther (2011) 0.83
Progress and challenges in viral vector manufacturing. Hum Mol Genet (2015) 0.83
Production of lentiviral vectors. Mol Ther Methods Clin Dev (2016) 0.82
A simple and effective method to generate lentiviral vectors for ex vivo gene delivery to mature human peripheral blood lymphocytes. Hum Gene Ther Methods (2012) 0.80
Lentiviral Vectors Mediate Long-Term and High Efficiency Transgene Expression in HEK 293T cells. Int J Med Sci (2015) 0.78
Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of human ORFs and identification of human genes affecting viral titer. PLoS One (2012) 0.78
High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors. Mol Ther Methods Clin Dev (2015) 0.75
High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res (2002) 6.64
MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci (2003) 1.54
Diastolic blood pressure and mortality in the elderly with cardiovascular disease. Hypertension (2007) 1.45
Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells. J Immunol (2013) 1.39
Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase. J Biol Chem (2004) 1.24
Large-scale transient transfection of serum-free suspension-growing HEK293 EBNA1 cells: peptone additives improve cell growth and transfection efficiency. Biotechnol Bioeng (2003) 1.18
Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Mol Ther (2008) 1.17
LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. J Neurosci (2010) 1.14
Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP. J Biol Chem (2006) 1.09
Development and optimization of an adenovirus production process. J Gene Med (2004) 1.09
Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. Carcinogenesis (2005) 1.06
Characterization of yeastolate fractions that promote insect cell growth and recombinant protein production. Cytotechnology (2007) 1.06
A novel Schistosoma mansoni G protein-coupled receptor is responsive to histamine. Mol Biochem Parasitol (2002) 1.06
Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound. Carcinogenesis (2005) 1.05
Improving glucose and glutamine metabolism of human HEK 293 and Trichoplusia ni insect cells engineered to express a cytosolic pyruvate carboxylase enzyme. Biotechnol Prog (2003) 1.04
Aortic pulse wave velocity: an independent marker of cardiovascular risk. Am J Geriatr Cardiol (2002) 1.04
Production of adenovirus vector for gene therapy. Biotechnol Adv (2003) 1.03
Inhibition of inflammatory mediators by polyphenolic plant extracts in human intestinal Caco-2 cells. Food Chem Toxicol (2009) 1.03
Transient expression and purification of chimeric heavy chain antibodies. Protein Expr Purif (2008) 1.03
Differential tumor-targeting abilities of three single-domain antibody formats. Cancer Lett (2009) 1.02
Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification. Biotechnol Bioeng (2007) 1.02
The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils. J Leukoc Biol (2009) 1.02
Identification of host proteins associated with retroviral vector particles by proteomic analysis of highly purified vector preparations. J Virol (2007) 1.01
Large-scale transfection of mammalian cells for the fast production of recombinant protein. Mol Biotechnol (2006) 0.99
Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells. J Virol Methods (2007) 0.99
Quantitation of baculovirus particles by flow cytometry. J Virol Methods (2002) 0.98
Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design. MAbs (2013) 0.98
Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells. BMC Biotechnol (2008) 0.97
Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing. Vaccine (2010) 0.97
Purification and characterization of a recombinant G-protein-coupled receptor, Saccharomyces cerevisiae Ste2p, transiently expressed in HEK293 EBNA1 cells. Biochemistry (2005) 0.96
Purification of recombinant proteins from mammalian cell culture using a generic double-affinity chromatography scheme. Protein Expr Purif (2005) 0.96
Epidermal growth factor and perlecan fragments produced by apoptotic endothelial cells co-ordinately activate ERK1/2-dependent antiapoptotic pathways in mesenchymal stem cells. Stem Cells (2010) 0.95
Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures. Biotechnol Bioeng (2004) 0.94
Stability of serum-free and purified baculovirus stocks under various storage conditions. Biotechnol Prog (2006) 0.93
R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea. Nat Commun (2013) 0.93
Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells. J Biotechnol (2006) 0.92
Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII. BMC Biotechnol (2011) 0.92
Effect of surface charge on the cellular uptake and cytotoxicity of fluorescent labeled cellulose nanocrystals. ACS Appl Mater Interfaces (2010) 0.92
Downstream processing of oncoretroviral and lentiviral gene therapy vectors. Biotechnol Adv (2006) 0.91
Efficient human hematopoietic cell transduction using RD114- and GALV-pseudotyped retroviral vectors produced in suspension and serum-free media. Hum Gene Ther (2009) 0.90
Moderate wine drinkers have lower hypertension-related mortality: a prospective cohort study in French men. Am J Clin Nutr (2004) 0.90
Transfection of HEK293-EBNA1 Cells in Suspension with Linear PEI for Production of Recombinant Proteins. CSH Protoc (2008) 0.89
A secreted enzyme reporter system for MRI. Angew Chem Int Ed Engl (2010) 0.89
Analytical technologies for influenza virus-like particle candidate vaccines: challenges and emerging approaches. Virol J (2013) 0.89
A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography. Biotechnol Bioeng (2005) 0.88
Primary recovery and chromatographic purification of adeno-associated virus type 2 produced by baculovirus/insect cell system. J Virol Methods (2006) 0.88
Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery. J Biol Chem (2008) 0.88
An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor. J Biol Chem (2014) 0.88
Insights into the central metabolism of Spodoptera frugiperda (Sf-9) and Trichoplusia ni BTI-Tn-5B1-4 (Tn-5) insect cells by radiolabeling studies. Biotechnol Prog (2005) 0.87
Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases. Prog Brain Res (2004) 0.86
Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability. Chem Biol Drug Des (2010) 0.86
The cell motility modulator Slit2 is a potent inhibitor of platelet function. Circulation (2012) 0.86
Analysis of baculovirus aggregates using flow cytometry. J Virol Methods (2005) 0.86
The perlecan fragment LG3 is a novel regulator of obliterative remodeling associated with allograft vascular rejection. Circ Res (2011) 0.86
IGFBP-4 anti-angiogenic and anti-tumorigenic effects are associated with anti-cathepsin B activity. Neoplasia (2013) 0.85
Size-exclusion chromatography purification of high-titer vesicular stomatitis virus G glycoprotein-pseudotyped retrovectors for cell and gene therapy applications. Hum Gene Ther (2003) 0.85
Production and formulation of adenovirus vectors. Adv Biochem Eng Biotechnol (2005) 0.84
Production of chimeric heavy-chain antibodies. Methods Mol Biol (2009) 0.84
New protocol for lentiviral vector mass production. Methods Mol Biol (2010) 0.84
Surface modification of nonviral nanocarriers for enhanced gene delivery. Nanomedicine (Lond) (2014) 0.84
Production of α2,6-sialylated IgG1 in CHO cells. MAbs (2015) 0.84
Enhanced glycoprotein production in HEK-293 cells expressing pyruvate carboxylase. Metab Eng (2011) 0.83
Purification and characterization of retrovirus vector particles by rate zonal ultracentrifugation. J Virol Methods (2005) 0.83
Very low oral doses of vitamin B-12 increase serum concentrations in elderly subjects with food-bound vitamin B-12 malabsorption. J Nutr (2007) 0.83
Salivary gland-sparing other than parotid-sparing in definitive head-and-neck intensity-modulated radiotherapy does not seem to jeopardize local control. Radiat Oncol (2013) 0.83
Plasminogen Kringle 5 blocks tumor progression by antiangiogenic and proinflammatory pathways. Mol Cancer Ther (2007) 0.83
Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis. Bioprocess Biosyst Eng (2010) 0.83
A simplified polyethylenimine-mediated transfection process for large-scale and high-throughput applications. Methods (2011) 0.82
Expressing full-length functional PfEMP1 proteins in the HEK293 expression system. Methods Mol Biol (2013) 0.82
Enhancement of the antagonistic potency of transforming growth factor-beta receptor extracellular domains by coiled coil-induced homo- and heterodimerization. J Biol Chem (2004) 0.82
A kinetic-metabolic model based on cell energetic state: study of CHO cell behavior under Na-butyrate stimulation. Bioprocess Biosyst Eng (2012) 0.82
Micro-quantitation of lipids in serum-free cell culture media: a critical aspect is the minimization of interference from medium components and chemical reagents. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.82
Probing inhibitory effects of Antrodia camphorata isolates using insect cell-based impedance spectroscopy: inhibition vs chemical structure. Chem Res Toxicol (2008) 0.82
High yield purification of functional baculovirus vectors by size exclusion chromatography. J Virol Methods (2007) 0.82
Insulin-like growth factor binding protein 7 exhibits tumor suppressive and vessel stabilization properties in U87MG and T98G glioblastoma cell lines. Cancer Biol Ther (2011) 0.82
VEGF increases the fibrinolytic activity of endothelial cells within fibrin matrices: involvement of VEGFR-2, tissue type plasminogen activator and matrix metalloproteinases. Thromb Res (2007) 0.82
Retroviral vector production using suspension-adapted 293GPG cells in a 3L acoustic filter-based perfusion bioreactor. Biotechnol Bioeng (2006) 0.81
Probing inhibitory effects of nanocrystalline cellulose: inhibition versus surface charge. Nanoscale (2012) 0.81
Recombinant protein production in large-scale agitated bioreactors using the baculovirus expression vector system. Methods Mol Biol (2007) 0.81
Probing the metabolism of an inducible mammalian expression system using extracellular isotopomer analysis. J Biotechnol (2013) 0.81
Exploiting heparin-binding properties of MoMLV-based retroviral vectors for affinity chromatography. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.80
Label-free detection of gliadin food allergen mediated by real-time apta-PCR. Anal Bioanal Chem (2013) 0.80
An efficient process for the purification of helper-dependent adenoviral vector and removal of helper virus by iodixanol ultracentrifugation. J Virol Methods (2010) 0.80
Engineering and therapeutic application of single-chain bivalent TGF-β family traps. Mol Cancer Ther (2012) 0.79
Stable expression of chimeric heavy chain antibodies in CHO cells. Methods Mol Biol (2012) 0.79
O-linked glycosylation leads to decreased thermal stability of interferon alpha 2b as measured by two orthogonal techniques. Pharm Res (2011) 0.79
Culture of HEK293-EBNA1 Cells for Production of Recombinant Proteins. CSH Protoc (2008) 0.79
Validation of a high-performance liquid chromatographic assay for the quantification of Reovirus particles type 3. J Pharm Biomed Anal (2007) 0.79
Impact of epidermal growth factor tethering strategy on cellular response. Bioconjug Chem (2010) 0.79