Published in Biotechnol Bioeng on November 01, 2007
Replication-competent lentivirus analysis of clinical grade vector products. Mol Ther (2010) 1.04
Role of the feline immunodeficiency virus L-domain in the presence or absence of Gag processing: involvement of ubiquitin and Nedd4-2s ligase in viral egress. J Cell Physiol (2009) 0.92
Simplified production and concentration of HIV-1-based lentiviral vectors using HYPERFlask vessels and anion exchange membrane chromatography. BMC Biotechnol (2009) 0.91
Viral vectors for in vivo gene transfer in Parkinson's disease: properties and clinical grade production. Exp Neurol (2007) 0.86
Efficient large volume lentiviral vector production using flow electroporation. Hum Gene Ther (2011) 0.83
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Manufacturing genetically modified T cells for clinical trials. Cancer Gene Ther (2015) 0.77
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E2F-1 overexpression inhibits human gastric cancer MGC-803 cell growth in vivo. World J Gastroenterol (2015) 0.76
High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors. Mol Ther Methods Clin Dev (2015) 0.75
Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen. Sci Rep (2017) 0.75
High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res (2002) 6.64
Polyploid megakaryocytes can complete cytokinesis. Cell Cycle (2010) 1.57
MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci (2003) 1.54
Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase. J Biol Chem (2004) 1.24
Large-scale transient transfection of serum-free suspension-growing HEK293 EBNA1 cells: peptone additives improve cell growth and transfection efficiency. Biotechnol Bioeng (2003) 1.18
Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Mol Ther (2008) 1.17
LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. J Neurosci (2010) 1.14
Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP. J Biol Chem (2006) 1.09
Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference, Lausanne, Switzerland, January 22-24, 2008. J Allergy Clin Immunol (2008) 1.08
Characterization of yeastolate fractions that promote insect cell growth and recombinant protein production. Cytotechnology (2007) 1.06
Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation. Carcinogenesis (2005) 1.06
A novel Schistosoma mansoni G protein-coupled receptor is responsive to histamine. Mol Biochem Parasitol (2002) 1.06
Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound. Carcinogenesis (2005) 1.05
Improving glucose and glutamine metabolism of human HEK 293 and Trichoplusia ni insect cells engineered to express a cytosolic pyruvate carboxylase enzyme. Biotechnol Prog (2003) 1.04
Production of adenovirus vector for gene therapy. Biotechnol Adv (2003) 1.03
Transient expression and purification of chimeric heavy chain antibodies. Protein Expr Purif (2008) 1.03
Differential tumor-targeting abilities of three single-domain antibody formats. Cancer Lett (2009) 1.02
The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils. J Leukoc Biol (2009) 1.02
Identification of host proteins associated with retroviral vector particles by proteomic analysis of highly purified vector preparations. J Virol (2007) 1.01
Large-scale transfection of mammalian cells for the fast production of recombinant protein. Mol Biotechnol (2006) 0.99
Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells. J Virol Methods (2007) 0.99
Quantitation of baculovirus particles by flow cytometry. J Virol Methods (2002) 0.98
Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design. MAbs (2013) 0.98
High-titer adenovirus vector production in 293S cell perfusion culture. Biotechnol Prog (2004) 0.97
Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells. BMC Biotechnol (2008) 0.97
Purification and characterization of a recombinant G-protein-coupled receptor, Saccharomyces cerevisiae Ste2p, transiently expressed in HEK293 EBNA1 cells. Biochemistry (2005) 0.96
Purification of recombinant proteins from mammalian cell culture using a generic double-affinity chromatography scheme. Protein Expr Purif (2005) 0.96
Epidermal growth factor and perlecan fragments produced by apoptotic endothelial cells co-ordinately activate ERK1/2-dependent antiapoptotic pathways in mesenchymal stem cells. Stem Cells (2010) 0.95
Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures. Biotechnol Bioeng (2004) 0.94
Stability of serum-free and purified baculovirus stocks under various storage conditions. Biotechnol Prog (2006) 0.93
R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea. Nat Commun (2013) 0.93
Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells. J Biotechnol (2006) 0.92
Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII. BMC Biotechnol (2011) 0.92
Effect of surface charge on the cellular uptake and cytotoxicity of fluorescent labeled cellulose nanocrystals. ACS Appl Mater Interfaces (2010) 0.92
Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design. Exp Hematol (2005) 0.91
Downstream processing of oncoretroviral and lentiviral gene therapy vectors. Biotechnol Adv (2006) 0.91
Selection and tuning of a fast and simple phase-contrast microscopy image segmentation algorithm for measuring myoblast growth kinetics in an automated manner. Microsc Microanal (2013) 0.91
Efficient human hematopoietic cell transduction using RD114- and GALV-pseudotyped retroviral vectors produced in suspension and serum-free media. Hum Gene Ther (2009) 0.90
Transfection of HEK293-EBNA1 Cells in Suspension with Linear PEI for Production of Recombinant Proteins. CSH Protoc (2008) 0.89
Peptidoglycan lytic activity of the Pseudomonas aeruginosa phage phiKZ gp144 lytic transglycosylase. FEMS Microbiol Lett (2007) 0.89
A secreted enzyme reporter system for MRI. Angew Chem Int Ed Engl (2010) 0.89
Megakaryocyte and platelet production from human cord blood stem cells. Methods Mol Biol (2012) 0.89
Overview of current scalable methods for purification of viral vectors. Methods Mol Biol (2011) 0.88
Primary recovery and chromatographic purification of adeno-associated virus type 2 produced by baculovirus/insect cell system. J Virol Methods (2006) 0.88
A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography. Biotechnol Bioeng (2005) 0.88
An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor. J Biol Chem (2014) 0.88
Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery. J Biol Chem (2008) 0.88
High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch. Biotechnol Bioeng (2010) 0.87
Insights into the central metabolism of Spodoptera frugiperda (Sf-9) and Trichoplusia ni BTI-Tn-5B1-4 (Tn-5) insect cells by radiolabeling studies. Biotechnol Prog (2005) 0.87
Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases. Prog Brain Res (2004) 0.86
Development of a scalable process for high-yield lentiviral vector production by transient transfection of HEK293 suspension cultures. J Gene Med (2009) 0.86
Analysis of baculovirus aggregates using flow cytometry. J Virol Methods (2005) 0.86
The perlecan fragment LG3 is a novel regulator of obliterative remodeling associated with allograft vascular rejection. Circ Res (2011) 0.86
The cell motility modulator Slit2 is a potent inhibitor of platelet function. Circulation (2012) 0.86
New developments in lentiviral vector design, production and purification. Expert Opin Biol Ther (2013) 0.86
Single-cell level analysis of megakaryocyte growth and development. Differentiation (2012) 0.86
Individual and synergistic cytokine effects controlling the expansion of cord blood CD34(+) cells and megakaryocyte progenitors in culture. Cytotherapy (2010) 0.85
High-level recombinant protein production in CHO cells using an adenoviral vector and the cumate gene-switch. Biotechnol Prog (2007) 0.85
Size-exclusion chromatography purification of high-titer vesicular stomatitis virus G glycoprotein-pseudotyped retrovectors for cell and gene therapy applications. Hum Gene Ther (2003) 0.85
IGFBP-4 anti-angiogenic and anti-tumorigenic effects are associated with anti-cathepsin B activity. Neoplasia (2013) 0.85
New protocol for lentiviral vector mass production. Methods Mol Biol (2010) 0.84
Production of chimeric heavy-chain antibodies. Methods Mol Biol (2009) 0.84
Production of α2,6-sialylated IgG1 in CHO cells. MAbs (2015) 0.84
Production and formulation of adenovirus vectors. Adv Biochem Eng Biotechnol (2005) 0.84
Surface modification of nonviral nanocarriers for enhanced gene delivery. Nanomedicine (Lond) (2014) 0.84
Purification and characterization of retrovirus vector particles by rate zonal ultracentrifugation. J Virol Methods (2005) 0.83
Enhanced glycoprotein production in HEK-293 cells expressing pyruvate carboxylase. Metab Eng (2011) 0.83
Plasminogen Kringle 5 blocks tumor progression by antiangiogenic and proinflammatory pathways. Mol Cancer Ther (2007) 0.83
Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis. Bioprocess Biosyst Eng (2010) 0.83
Expressing full-length functional PfEMP1 proteins in the HEK293 expression system. Methods Mol Biol (2013) 0.82
Probing inhibitory effects of Antrodia camphorata isolates using insect cell-based impedance spectroscopy: inhibition vs chemical structure. Chem Res Toxicol (2008) 0.82
A simplified polyethylenimine-mediated transfection process for large-scale and high-throughput applications. Methods (2011) 0.82
VEGF increases the fibrinolytic activity of endothelial cells within fibrin matrices: involvement of VEGFR-2, tissue type plasminogen activator and matrix metalloproteinases. Thromb Res (2007) 0.82
Ex vivo megakaryocyte expansion and platelet production from human cord blood stem cells. Methods Mol Biol (2009) 0.82
Insulin-like growth factor binding protein 7 exhibits tumor suppressive and vessel stabilization properties in U87MG and T98G glioblastoma cell lines. Cancer Biol Ther (2011) 0.82
Enhancement of the antagonistic potency of transforming growth factor-beta receptor extracellular domains by coiled coil-induced homo- and heterodimerization. J Biol Chem (2004) 0.82
High yield purification of functional baculovirus vectors by size exclusion chromatography. J Virol Methods (2007) 0.82
Micro-quantitation of lipids in serum-free cell culture media: a critical aspect is the minimization of interference from medium components and chemical reagents. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.82
Retroviral vector production using suspension-adapted 293GPG cells in a 3L acoustic filter-based perfusion bioreactor. Biotechnol Bioeng (2006) 0.81
Recombinant protein production in large-scale agitated bioreactors using the baculovirus expression vector system. Methods Mol Biol (2007) 0.81
Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteins. BMC Biotechnol (2009) 0.81
Probing inhibitory effects of nanocrystalline cellulose: inhibition versus surface charge. Nanoscale (2012) 0.81
Exploiting heparin-binding properties of MoMLV-based retroviral vectors for affinity chromatography. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.80