Published in Cancer Sci on June 23, 2009
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miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC). Br J Cancer (2010) 1.61
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Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients. Breast Cancer Res (2012) 1.43
Current findings for recurring mutations in acute myeloid leukemia. J Hematol Oncol (2011) 1.33
Turnover of focal adhesions and cancer cell migration. Int J Cell Biol (2012) 1.22
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion. Oncogene (2011) 1.18
SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans. J Clin Invest (2011) 1.16
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The tumor suppressor role of Src homology phosphotyrosine phosphatase 2 in hepatocellular carcinoma. J Cancer Res Clin Oncol (2012) 0.90
Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma. Biochem Biophys Res Commun (2013) 0.88
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation. J Immunol (2012) 0.87
Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes. Exp Hematol (2012) 0.86
Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun (2015) 0.85
Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium. PLoS One (2014) 0.84
Vinculin functions as regulator of chondrogenesis. J Biol Chem (2012) 0.84
A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth. Oncotarget (2016) 0.84
Deletion of SHP-2 in mesenchymal stem cells causes growth retardation, limb and chest deformity, and calvarial defects in mice. Dis Model Mech (2013) 0.83
Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice. Mol Cell Biol (2015) 0.83
Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice. PLoS One (2014) 0.83
Prolactin receptor-integrin cross-talk mediated by SIRPα in breast cancer cells. Mol Cancer Res (2010) 0.82
Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4. J Lipid Res (2011) 0.81
The Mitogen-Activated Protein Kinase (MAPK) Pathway: Role in Immune Evasion by Trypanosomatids. Front Microbiol (2016) 0.80
Role of SH2-containing tyrosine phosphatase Shp2 in mouse corneal epithelial stratification. Invest Ophthalmol Vis Sci (2013) 0.80
SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans. Oncogene (2016) 0.80
N-Acetyl-seryl-aspartyl-lysyl-proline inhibits ET-1-induced collagen production by preserving Src homology 2-containing protein tyrosine phosphatase-2 activity in cardiac fibroblasts. Pflugers Arch (2012) 0.79
Discovery of a Novel Inhibitor of the Protein Tyrosine Phosphatase Shp2. Sci Rep (2015) 0.78
Reactive oxygen species and epidermal growth factor are antagonistic cues controlling SHP-2 dimerization. Mol Cell Biol (2012) 0.78
Vascular endothelial growth factor (VEGF) and platelet (PF-4) factor 4 inputs modulate human microvascular endothelial signaling in a three-dimensional matrix migration context. Mol Cell Proteomics (2013) 0.77
Role of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function. Front Endocrinol (Lausanne) (2016) 0.76
Novel CagA ELISA exhibits enhanced sensitivity of Helicobacter pylori CagA antibody. World J Gastroenterol (2017) 0.75
Research progress of neuroblastoma related gene variations. Oncotarget (2016) 0.75
Peripheral blood cells from children with RASopathies show enhanced spontaneous colonies growth in vitro and hyperactive RAS signaling. Blood Cancer J (2015) 0.75
Identification of novel genetic loci for osteoporosis and/or rheumatoid arthritis using cFDR approach. PLoS One (2017) 0.75
Increased PTPRA expression leads to poor prognosis through c-Src activation and G1 phase progression in squamous cell lung cancer. Int J Oncol (2017) 0.75
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature (2004) 4.92
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev (2010) 3.37
The muscle protein Dok-7 is essential for neuromuscular synaptogenesis. Science (2006) 2.26
Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway. Trends Cell Biol (2009) 2.19
Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system. J Immunol (2005) 1.86
Estrogen determines sex differences in airway responsiveness after allergen exposure. Am J Respir Cell Mol Biol (2007) 1.63
Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis. Gastroenterology (2012) 1.43
Structure of the cadherin-related neuronal receptor/protocadherin-alpha first extracellular cadherin domain reveals diversity across cadherin families. J Biol Chem (2006) 1.38
Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1. J Biol Chem (2002) 1.30
Promotion of neurite and filopodium formation by CD47: roles of integrins, Rac, and Cdc42. Mol Biol Cell (2004) 1.16
Stress-evoked tyrosine phosphorylation of signal regulatory protein α regulates behavioral immobility in the forced swim test. J Neurosci (2010) 1.10
Role of the CD47-SHPS-1 system in regulation of cell migration. EMBO J (2003) 1.10
Dendritic cell-specific ablation of the protein tyrosine phosphatase Shp1 promotes Th1 cell differentiation and induces autoimmunity. J Immunol (2012) 1.09
SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages. Blood (2005) 1.08
Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation. J Exp Med (2008) 1.05
Positive regulation of phagocytosis by SIRPbeta and its signaling mechanism in macrophages. J Biol Chem (2004) 1.05
Virus-specific IgE enhances airway responsiveness on reinfection with respiratory syncytial virus in newborn mice. J Allergy Clin Immunol (2008) 1.03
SIRPα/CD172a regulates eosinophil homeostasis. J Immunol (2011) 1.03
CD47 promotes neuronal development through Src- and FRG/Vav2-mediated activation of Rac and Cdc42. J Neurosci (2006) 1.03
Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues. Blood (2010) 1.02
Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes. Blood (2011) 1.02
Expression, localization, and biological function of the R3 subtype of receptor-type protein tyrosine phosphatases in mammals. Cell Signal (2010) 1.00
Src family kinases: modulators of neurotransmitter receptor function and behavior. Trends Neurosci (2011) 0.99
Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system. J Cell Sci (2008) 0.98
Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids. J Allergy Clin Immunol (2013) 0.97
Hemoperitoneum secondary to spontaneous rupture of hepatic metastasis from lung cancer. Intern Med (2005) 0.96
Cadherin-related neuronal receptor 1 (CNR1) has cell adhesion activity with beta1 integrin mediated through the RGD site of CNR1. Exp Cell Res (2004) 0.96
Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins. J Cell Physiol (2010) 0.96
SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress. J Neurochem (2012) 0.94
Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation. Am J Respir Cell Mol Biol (2008) 0.93
Genomic organization and transcripts of the zebrafish Protocadherin genes. Gene (2004) 0.93
Leukotriene B4 receptor 1 expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway hyperresponsiveness. J Immunol (2008) 0.92
Differential localization of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 and CD47 and its molecular mechanisms in cultured hippocampal neurons. J Neurosci (2005) 0.90
Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation. J Biol Chem (2012) 0.90
Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction. Proc Natl Acad Sci U S A (2007) 0.89
A Nationwide Survey of Hepatitis E Virus Infection and Chronic Hepatitis E in Liver Transplant Recipients in Japan. EBioMedicine (2015) 0.89
SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis. Genes Cells (2009) 0.89
Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice. J Immunol (2007) 0.89
Enhanced phagocytosis of CD47-deficient red blood cells by splenic macrophages requires SHPS-1. Biochem Biophys Res Commun (2006) 0.89
A multi-institutional survey of the effectiveness of chemotherapy combined with radiotherapy for patients with nasopharyngeal carcinoma. Jpn J Clin Oncol (2004) 0.89
Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes. J Immunol (2004) 0.89
Lack of benefit of spinal irradiation in the primary treatment of intracranial germinoma: a multiinstitutional, retrospective review of 180 patients. Cancer (2005) 0.89
Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain. Biochem Biophys Res Commun (2003) 0.88
Structural insight into the specific interaction between murine SHPS-1/SIRP alpha and its ligand CD47. J Mol Biol (2007) 0.87
Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn. Genes Cells (2010) 0.87
Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages. Genes Cells (2008) 0.87
Ectodomain shedding of SHPS-1 and its role in regulation of cell migration. J Biol Chem (2004) 0.85
Signal regulatory protein α regulates the homeostasis of T lymphocytes in the spleen. J Immunol (2011) 0.85
CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease. J Immunol (2010) 0.85
CD47 regulation of epithelial cell spreading and migration, and its signal transduction. Cancer Sci (2006) 0.85
Inflammation-induced proteolytic processing of the SIRPα cytoplasmic ITIM in neutrophils propagates a proinflammatory state. Nat Commun (2013) 0.85
Regulation of multiple functions of SHPS-1, a transmembrane glycoprotein, by its cytoplasmic region. Biochem Biophys Res Commun (2003) 0.85
Ubiquitination-mediated regulation of biosynthesis of the adhesion receptor SHPS-1 in response to endoplasmic reticulum stress. J Biol Chem (2003) 0.84
CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity. Neuroreport (2004) 0.84
Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the induction of Langerhans cell maturation. Eur J Immunol (2006) 0.84
Results of radiation therapy for superficial esophageal cancer using the standard radiotherapy method recommended by the Japanese Society of Therapeutic Radiology and Oncology (JASTRO) Study Group. Anticancer Res (2006) 0.84
Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of alpha-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells. J Immunol (2007) 0.83